{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.metabolism","code":"thing-q1057","url":"https://ver.cy/models/thing/q1057/","name":"metabolism","alternateNames":[],"kind":"thing","status":"published","version":"0.2.0-wave.1","language":"en","classifiers":{"family":"Thing Registry","category":"Activities and processes","entryKind":"thing","plane":"ACT","domain":["ACT.PRC"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"The set of chemical reactions in living organisms that convert food into energy and building blocks, and eliminate waste, including catabolism and anabolism.","purpose":"Let an agent explain metabolism accurately, separate scientific facts from diet marketing, and direct individual metabolic health questions to clinicians.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["All chemical reactions of life","Catabolism breaks down; anabolism builds up","Regulated by enzymes and hormones","Popular claims about boosting metabolism are often unsupported"],"structure":{"bundles":[{"id":"pathways","name":"Pathways","description":"What reactions.","layers":[{"id":"pathway","name":"Pathway","description":"Named pathway.","findings":[{"id":"pathway-finding","name":"Pathway","description":"Pathway.","questions":[{"text":"Which metabolic pathway is involved?","kind":"definition"},{"text":"What does it produce?","kind":"definition"}]}]},{"id":"regulation","name":"Regulation","description":"Control.","findings":[{"id":"regulation-finding","name":"Regulation","description":"Regulation.","questions":[{"text":"How is the pathway regulated?","kind":"definition"},{"text":"Which hormones affect it?","kind":"definition"}]}]}]},{"id":"measurement","name":"Measurement","description":"Metabolic rate and tests.","layers":[{"id":"rate","name":"Rate","description":"Energy use.","findings":[{"id":"rate-finding","name":"Rate","description":"Metabolic rate.","questions":[{"text":"How is metabolic rate measured?","kind":"definition"},{"text":"What affects it?","kind":"definition"}]}]},{"id":"tests","name":"Tests","description":"Blood tests.","findings":[{"id":"tests-finding","name":"Tests","description":"Clinical tests.","questions":[{"text":"Which tests assess metabolism clinically?","kind":"definition"},{"text":"Who should interpret them?","kind":"action"}]}]}]},{"id":"health","name":"Health","description":"Disorders.","layers":[{"id":"disorders","name":"Disorders","description":"Metabolic disease.","findings":[{"id":"disorders-finding","name":"Disorders","description":"Metabolic disorders.","questions":[{"text":"Which disorders affect metabolism?","kind":"definition"},{"text":"When should someone see a doctor?","kind":"action"}]}]},{"id":"claims","name":"Claims","description":"Diet marketing.","findings":[{"id":"claims-finding","name":"Claims","description":"Evaluating claims.","questions":[{"text":"Is a claim to boost metabolism supported by evidence?","kind":"boundary"},{"text":"Which authority assessed it?","kind":"provenance"}]}]}]},{"id":"applications","name":"Applications","description":"Biotech and drugs.","layers":[{"id":"drugs","name":"Drug metabolism","description":"Interactions.","findings":[{"id":"drugs-finding","name":"Drug metabolism","description":"How drugs are processed.","questions":[{"text":"How is a medicine metabolised?","kind":"definition"},{"text":"Which interactions matter?","kind":"boundary"}]}]},{"id":"biotech","name":"Biotechnology","description":"Engineering.","findings":[{"id":"biotech-finding","name":"Biotech","description":"Metabolic engineering.","questions":[{"text":"How is metabolism engineered in industry?","kind":"definition"},{"text":"Which rules apply?","kind":"provenance"}]}]}]}]},"agentConduct":{"may":["Explain metabolism and its pathways from established sources.","Help a person track diet and activity data they choose to share."],"mustNot":["Promise to change a person's metabolism through products or regimes without evidence.","Recommend extreme diets, fasting or supplements without medical supervision.","Diagnose a metabolic disorder or adjust treatment such as insulin.","Use metabolic or body data to shame or discriminate against a person."],"requiresHuman":["Changing medication or nutrition for a person with a metabolic disease."]},"ethics":{"considerations":["Claims about metabolism are widely used to sell ineffective or harmful weight-loss products.","Body and health data are sensitive and can stigmatize people."],"affectedParties":["People seeking health advice","People with metabolic disorders"]},"owners":{"steward":"Nobody owns the concept; clinicians answer for each patient's care.","roles":[],"masterSystems":[]},"relations":[{"target":"Q2996394","type":"parent","note":"registry parent class"},{"target":"biological process","type":"related","note":"process"},{"target":"protein","type":"related","note":"enzymes"},{"target":"energy","type":"related","note":"ATP"},{"target":"autosomal recessive disease","type":"related","note":"metabolic disorders"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.metabolism","Wikidata: Q1057 (https://www.wikidata.org/wiki/Q1057)","KEGG pathway id: map plus digits metabolic pathways","GO biological process: GO:0008152 metabolic process"]},"properties":{"applicability":"not-applicable","items":["adult basal metabolic rate: about 1200-2000 kcal per day - varies with body size and sex"]},"recognition":{"applicability":"optional","items":["Metabolic pathways in diagrams","Basal metabolic rate measurements","Metabolic disorders named in medicine","Not visible; measured through energy use, blood tests and biochemical assays."]},"capabilities":{"applicability":"required","items":["study it in biochemistry","measure metabolic rate","diagnose metabolic disorders, by clinicians","engineer it in biotechnology"]},"hazards":{"applicability":"required","items":["Unsupported diet claims","Individual medical advice","Oversimplifying metabolic disease"]},"interfaces":{"applicability":"required","items":["Health claims regulation for foods such as EU Regulation 1924/2006"]},"context":{"applicability":"required","items":["Metabolism keeps organisms alive; understanding it informs nutrition, medicine and biotechnology.","energy metabolism","carbohydrate, lipid and protein metabolism","drug metabolism","inborn errors of metabolism"]}},"sources":[{"title":"Wikidata item Q1057: metabolism","url":"https://www.wikidata.org/wiki/Q1057","note":"identity and sense of the item"},{"title":"Wikipedia: Metabolism","url":"https://en.wikipedia.org/wiki/Metabolism","note":"general description of the item"}],"openQuestions":["Should pathways be separate entries?","How should diet claims be checked?","How should metabolic disorders be linked?"],"resources":{"spec":"/models/things/publications/thing-q1057/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q1057/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-11T06:19:07Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"not-applicable","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-06T19:51:53+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass","interaction.properties":"Plane ACT: no invented physical properties."},"score":1.0}}