{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.parkinson-s-disease","code":"thing-q11085","url":"https://ver.cy/models/thing/q11085/","name":"Parkinson's disease","alternateNames":["Parkinson’s disease dementia","dopamine dysregulation syndrome","young-onset Parkinson disease","Parkinson’s disease psychosis","late-onset Parkinson disease","Parkinson disease, mitochondrial","PARK16","Parkinson disease 22, autosomal dominant; PARK22","Parkinson's disease 3"],"kind":"thing","status":"published","version":"0.2.0-wave.2","language":"en","classifiers":{"family":"Thing Registry","category":"Cross-cutting context","entryKind":"thing","plane":"XCT","domain":["XCT.STA"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"A progressive neurodegenerative disorder characterised by tremor, slowness of movement, rigidity and postural instability, with non-motor features such as sleep disturbance, mood changes, and in some people cognitive decline, psychosis or dopamine dysregulation, caused by loss of dopamine-producing neurons and the accumulation of alpha-synuclein, in young-onset, late-onset and genetic forms; the disease is managed with medication, therapies and sometimes surgery, and this entry gives general information only, not personal medical advice.","purpose":"Let an agent explain Parkinson disease in general terms with attribution to medical sources, describe symptoms, diagnosis, treatments and support as documented, and route personal questions to clinicians.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Progressive","Motor and non-motor features","Alpha-synuclein pathology","Treatable symptoms"],"structure":{"bundles":[{"id":"understand","name":"Understand","description":"What Parkinson disease is.","layers":[{"id":"features","name":"Features","description":"Symptoms and course.","findings":[{"id":"features-finding","name":"Features","description":"Features.","questions":[{"text":"What are the motor and non-motor features of Parkinson disease, and how does it progress, according to medical sources?","kind":"provenance"},{"text":"Is the user asking about their own or a relative health, which needs a clinician?","kind":"boundary"}]}]},{"id":"causes","name":"Causes","description":"Causes and forms.","findings":[{"id":"causes-finding","name":"Causes","description":"Causes.","questions":[{"text":"What is known about causes, including genetics, environment and alpha-synuclein, and how do young-onset and late-onset forms differ?","kind":"provenance"},{"text":"Which entry fits a specific form?","kind":"action"}]}]}]},{"id":"care","name":"Care","description":"Diagnosis and treatment.","layers":[{"id":"diagnosis","name":"Diagnosis","description":"Diagnosis.","findings":[{"id":"diagnosis-finding","name":"Diagnosis","description":"Diagnosis.","questions":[{"text":"How is Parkinson disease diagnosed and distinguished from other causes of parkinsonism, in general terms?","kind":"provenance"},{"text":"Which specialists are involved?","kind":"provenance"}]}]},{"id":"treatment","name":"Treatment","description":"Treatments.","findings":[{"id":"treatment-finding","name":"Treatment","description":"Treatments.","questions":[{"text":"What treatments are documented, including medication, therapies and deep brain stimulation, and what complications such as dopamine dysregulation are described?","kind":"provenance"},{"text":"Which entry fits a specific treatment?","kind":"action"}]}]}]},{"id":"support","name":"Support","description":"Living with the disease.","layers":[{"id":"support","name":"Support","description":"Support resources.","findings":[{"id":"support-finding","name":"Support","description":"Support.","questions":[{"text":"What support exists for people with Parkinson disease and carers, and what do organisations offer?","kind":"provenance"},{"text":"Is someone in crisis, needing urgent help?","kind":"boundary"}]}]},{"id":"daily","name":"Daily","description":"Daily life.","findings":[{"id":"daily-finding","name":"Daily","description":"Daily life.","questions":[{"text":"What is documented about exercise, nutrition and daily living with the disease?","kind":"provenance"},{"text":"Which entry fits neurological rehabilitation?","kind":"action"}]}]}]},{"id":"learn","name":"Learn","description":"Research and history.","layers":[{"id":"research","name":"Research","description":"Research.","findings":[{"id":"research-finding","name":"Research","description":"Research.","questions":[{"text":"What are current research directions, and which claims are premature?","kind":"provenance"},{"text":"Which findings are contested?","kind":"boundary"}]}]},{"id":"history","name":"History","description":"History.","findings":[{"id":"history-finding","name":"History","description":"History.","questions":[{"text":"How was the disease described by James Parkinson, and how has understanding developed?","kind":"provenance"},{"text":"Which references are standard?","kind":"provenance"}]}]}]}]},"agentConduct":{"may":["Explain Parkinson's disease, its symptoms and care from health authorities and research bodies.","Point people to specialist services and patient support organisations."],"mustNot":["Give personal diagnosis, prognosis or medication advice.","Promote unproven cures or suggest stopping prescribed medicines.","Mock tremor, movement or speech changes, or use the condition as an insult.","Disclose a person's diagnosis without consent."],"requiresHuman":["Any decision about treatment, surgery or trial enrolment for a specific person."]},"ethics":{"considerations":["People with the disease face loss of independence and stigma for visible symptoms.","Some medicines can cause compulsive behaviour that patients and families must be told about."],"affectedParties":["People with Parkinson's","Carers and families"]},"owners":{"steward":"Nobody owns the condition; clinicians answer for care.","roles":[],"masterSystems":[]},"relations":[{"target":"Q2376264","type":"parent","note":"registry parent class"},{"target":"synucleinopathy","type":"related","note":"category"},{"target":"thought disorder","type":"related","note":"psychiatric features"},{"target":"memory","type":"related","note":"cognitive changes"},{"target":"psychologist","type":"related","note":"supporting care"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.parkinson-s-disease","Wikidata: Q11085 (https://www.wikidata.org/wiki/Q11085)"]},"properties":{"applicability":"not-applicable","items":[]},"recognition":{"applicability":"optional","items":["Tremor, slowness, rigidity","Dopamine neuron loss","Parkinsonism from other causes and essential tremor are distinct","Not visible as a disease; motor signs observed clinically."]},"capabilities":{"applicability":"required","items":["explain the condition generally","describe diagnosis and treatment","point to support","route personal questions"]},"hazards":{"applicability":"required","items":["Agents giving personal medical advice","Misinformation about cures","Stigma"]},"interfaces":{"applicability":"required","items":["Clinical guidelines from neurology bodies","Drug regulation for treatments","Disability and care support frameworks"]},"context":{"applicability":"required","items":["A neurodegenerative movement disorder.","typical late-onset Parkinson disease","young-onset Parkinson disease","genetic and mitochondrial forms","Parkinson disease with dementia or psychosis","related syndromes such as dopamine dysregulation"]}},"sources":[{"title":"Wikidata item Q11085: Parkinson's disease","url":"https://www.wikidata.org/wiki/Q11085","note":"identity and sense of the item"},{"title":"Wikipedia: Parkinson's disease","url":"https://en.wikipedia.org/wiki/Parkinson%27s_disease","note":"general description of the item"}],"openQuestions":["Should each form be a separate entry?","How should guidelines be linked?","How should support organisations be linked?"],"resources":{"spec":"/models/things/publications/thing-q11085/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q11085/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-12T02:02:12Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"not-applicable","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-06T19:51:53+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass","interaction.properties":"Plane XCT: no invented physical properties."},"score":1.0}}