{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.hormone","code":"thing-q11364","url":"https://ver.cy/models/thing/q11364/","name":"hormone","alternateNames":["sugar hormone","Neurohormone","synthetic hormone","Happy hormone","incretins","happiness hormone","melatonin","thyroid-stimulating hormone","stress hormone","hormone  of the thymus gland","bovine somatotropin","estrogen"],"kind":"thing","status":"published","version":"0.2.0-wave.1","language":"en","classifiers":{"family":"Thing Registry","category":"Physical world and living systems","entryKind":"thing","plane":"PHY","domain":["PHY.LIV"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"A signalling molecule produced by glands or cells and carried, often in the blood, to act on distant target cells, regulating growth, metabolism, reproduction, mood and other functions; examples include insulin, cortisol, oestrogen, testosterone and thyroid hormones.","purpose":"Let an agent explain hormones in general terms by source, target and function, and point to clinicians for testing and treatment, without personal medical advice.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Chemical messenger","Acts on distant targets","Regulated by feedback","Some used as medicines"],"structure":{"bundles":[{"id":"biology","name":"Biology","description":"Function.","layers":[{"id":"source","name":"Source","description":"Gland.","findings":[{"id":"source-finding","name":"Source","description":"Source and target.","questions":[{"text":"Which gland produces this hormone and what does it act on?","kind":"definition"},{"text":"Which sources describe it?","kind":"provenance"}]}]},{"id":"regulation","name":"Regulation","description":"Feedback.","findings":[{"id":"regulation-finding","name":"Regulation","description":"Regulation.","questions":[{"text":"How is its level regulated by feedback?","kind":"definition"},{"text":"What affects it?","kind":"definition"}]}]}]},{"id":"health","name":"Health","description":"Clinical care.","layers":[{"id":"testing","name":"Testing","description":"Tests.","findings":[{"id":"testing-finding","name":"Testing","description":"Hormone tests.","questions":[{"text":"Is the user asking to interpret their own hormone results?","kind":"boundary"},{"text":"How should they discuss them with a clinician?","kind":"action"}]}]},{"id":"therapy","name":"Therapy","description":"Treatments.","findings":[{"id":"therapy-finding","name":"Therapy","description":"Hormone therapy.","questions":[{"text":"What hormone therapies exist, in general terms?","kind":"definition"},{"text":"Who prescribes them?","kind":"provenance"}]}]}]},{"id":"safety","name":"Safety","description":"Products.","layers":[{"id":"products","name":"Products","description":"Supplements.","findings":[{"id":"products-finding","name":"Products","description":"Unregulated products.","questions":[{"text":"Is a product claiming to change hormones regulated?","kind":"boundary"},{"text":"Which regulator can confirm?","kind":"provenance"}]}]},{"id":"sport","name":"Sport","description":"Doping.","findings":[{"id":"sport-finding","name":"Sport","description":"Doping rules.","questions":[{"text":"Is this hormone prohibited in sport?","kind":"provenance"},{"text":"Which list applies?","kind":"provenance"}]}]}]},{"id":"clarity","name":"Clarity","description":"Accurate language.","layers":[{"id":"claims","name":"Claims","description":"Pop science.","findings":[{"id":"claims-finding","name":"Claims","description":"Popular claims.","questions":[{"text":"Is a popular claim, such as happy hormones, oversimplified?","kind":"boundary"},{"text":"What does evidence say?","kind":"provenance"}]}]},{"id":"plants","name":"Plants","description":"Plant hormones.","findings":[{"id":"plants-finding","name":"Plants","description":"Plant hormones.","questions":[{"text":"Are plant hormones such as auxins meant?","kind":"boundary"},{"text":"Which entry fits?","kind":"action"}]}]}]}]},"agentConduct":{"may":["Explain what hormones do in the body, citing medical sources.","Help a patient track their own prescribed hormone doses at their request."],"mustNot":["Recommend starting, stopping or changing hormone treatment for a person.","Help obtain hormones without a prescription or for doping.","Disclose a person's hormone treatment or levels without consent.","Make health claims for hormone products that the evidence does not support."],"requiresHuman":["Any decision on hormone therapy."]},"ethics":{"considerations":["Hormone treatments are linked to sensitive matters such as fertility, menopause and gender.","Misuse of hormones harms health and undermines fair sport."],"affectedParties":["Patients","Athletes","Children and adolescents"]},"owners":{"steward":"Nobody: a class of biological molecules; prescribers and medicines regulators answer for therapeutic use.","roles":[],"masterSystems":[]},"relations":[{"target":"Q12140","type":"parent","note":"registry parent class"},{"target":"Q1993433","type":"parent","note":"registry parent class"},{"target":"Q206229","type":"parent","note":"registry parent class"},{"target":"Q420168","type":"parent","note":"registry parent class"},{"target":"Q50430050","type":"parent","note":"registry parent class"},{"target":"Q522244","type":"parent","note":"registry parent class"},{"target":"signalling molecule","type":"related","note":"category"},{"target":"endocrine gland","type":"related","note":"source"},{"target":"endocrinology","type":"related","note":"field"},{"target":"medication","type":"related","note":"therapy"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.hormone","Wikidata: Q11364 (https://www.wikidata.org/wiki/Q11364)"]},"properties":{"applicability":"required","items":["Molar mass:  grams per mole - Molar mass is established for the identified hormone and molecular form using chemical composition or mass spectrometry.","Amount concentration:  moles per liter - Concentration is measured in a specified sample using a validated assay, with results dependent on the hormone, sample matrix and collection conditions.","Solubility:  grams per liter - Solubility is measured in a specified solvent at stated temperature and pH because hormones differ substantially in chemical structure."]},"recognition":{"applicability":"required","items":["Peptide, steroid and amine hormones","Glands such as thyroid, adrenal, pituitary","Plant hormones are a related category","Invisible molecules; measured in blood, urine or saliva."]},"capabilities":{"applicability":"required","items":["explain what a hormone does in general terms","identify glands and targets","understand hormone tests at a general level","find endocrinology services"]},"hazards":{"applicability":"required","items":["Agents giving personal hormone advice","Unregulated hormone products","Oversimplified happy hormone claims"]},"interfaces":{"applicability":"required","items":["Medicines regulation for hormone therapies","Anti-doping rules on hormones in sport"]},"context":{"applicability":"required","items":["Coordinating body functions.","peptide hormones such as insulin","steroid hormones such as cortisol","amine hormones such as thyroid hormones","neurohormones","plant hormones (related)"]}},"sources":[{"title":"Wikidata item Q11364: hormone","url":"https://www.wikidata.org/wiki/Q11364","note":"identity and sense of the item"},{"title":"Wikipedia: Hormone","url":"https://en.wikipedia.org/wiki/Hormone","note":"general description of the item"}],"openQuestions":["Should each hormone be a separate entry?","How should reference ranges be handled safely?","How should plant hormones be split off?"],"resources":{"spec":"/models/things/publications/thing-q11364/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q11364/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-11T10:13:09Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"filled","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-07T10:10:25+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass"},"score":1.0}}