{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.cholera","code":"thing-q12090","url":"https://ver.cy/models/thing/q12090/","name":"cholera","alternateNames":["cholera infantum","Vibrio cholerae O139 cholera","El Tor cholera"],"kind":"thing","status":"published","version":"0.2.0-wave.5","language":"en","classifiers":{"family":"Thing Registry","category":"Activities and processes","entryKind":"thing","plane":"ACT","domain":["ACT.ACT"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"An acute diarrhoeal infection of the small intestine caused by toxigenic strains of the bacterium Vibrio cholerae (serogroups O1 and O139), spread through contaminated water and food; severe cases cause rapid dehydration and can be fatal within hours without treatment, which is mainly oral or intravenous rehydration.","purpose":"Let an agent explain cholera, transmission, prevention and treatment in general terms, and point to WHO and public health guidance, without diagnosing.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Most infected people have mild or no symptoms but can spread the bacteria.","Oral rehydration solution can treat most cases; antibiotics are added for severe cases.","Oral cholera vaccines are WHO-prequalified and used in outbreaks through a global stockpile."],"structure":{"bundles":[{"id":"disease","name":"Disease","description":"Which form.","layers":[{"id":"agent","name":"Agent","description":"Serogroup.","findings":[{"id":"agent","name":"Agent","description":"Serogroup and biotype.","questions":[{"text":"Which serogroup?","kind":"provenance"},{"text":"Per which laboratory?","kind":"provenance"}]}]},{"id":"setting","name":"Setting","description":"Endemic or outbreak.","findings":[{"id":"setting","name":"Setting","description":"Type.","questions":[{"text":"Endemic or outbreak?","kind":"boundary"},{"text":"Per which agency?","kind":"provenance"}]}]}]},{"id":"transmission","name":"Transmission","description":"Spread.","layers":[{"id":"sources","name":"Sources","description":"Contamination.","findings":[{"id":"source","name":"Source","description":"Description.","questions":[{"text":"What is the likely source?","kind":"provenance"},{"text":"Per which investigation?","kind":"provenance"}]}]},{"id":"prevention","name":"Prevention","description":"Measures.","findings":[{"id":"prevention","name":"Prevention","description":"Measure.","questions":[{"text":"Which prevention measures?","kind":"provenance"},{"text":"Per WHO guidance?","kind":"provenance"}]}]}]},{"id":"care","name":"Care","description":"Treatment.","layers":[{"id":"rehydration","name":"Rehydration","description":"Fluids.","findings":[{"id":"rehydration","name":"Rehydration","description":"Approach.","questions":[{"text":"Which rehydration approach?","kind":"provenance"},{"text":"Per which guideline?","kind":"provenance"}]}]},{"id":"vaccines","name":"Vaccines","description":"Prevention.","findings":[{"id":"vaccine","name":"Vaccine","description":"Name.","questions":[{"text":"Which vaccines are available?","kind":"provenance"},{"text":"Per WHO prequalification?","kind":"provenance"}]}]}]},{"id":"surveillance","name":"Surveillance","description":"Data.","layers":[{"id":"cases","name":"Cases","description":"Counts.","findings":[{"id":"cases","name":"Cases","description":"Suspected, probable and confirmed cases, with reporting authority, case definition and period.","questions":[{"text":"How many cases?","kind":"measurement"},{"text":"Per which report?","kind":"provenance"}]}]},{"id":"response","name":"Response","description":"Actions.","findings":[{"id":"response","name":"Response","description":"Action.","questions":[{"text":"What response is under way?","kind":"provenance"},{"text":"By which agency?","kind":"provenance"}]}]}]}]},"agentConduct":{"may":["give general information and point to WHO guidance"],"mustNot":["diagnose or prescribe"],"requiresHuman":["suspected cases to health services urgently"]},"ethics":{"considerations":["health equity","access to clean water"],"affectedParties":["affected communities"]},"owners":{"steward":"nobody; a disease","roles":[],"masterSystems":["WHO","ICD (WHO)"]},"relations":[{"target":"Q1049711","type":"parent","note":"registry parent class"},{"target":"Q131345497","type":"parent","note":"registry parent class"},{"target":"Q18553247","type":"parent","note":"registry parent class"},{"target":"Q2006636","type":"parent","note":"registry parent class"},{"target":"Q2970970","type":"parent","note":"registry parent class"},{"target":"Q936236","type":"parent","note":"registry parent class"},{"target":"Vibrio cholerae","type":"related","note":"bacterium"},{"target":"water, sanitation and hygiene","type":"related","note":"measures"},{"target":"oral rehydration therapy","type":"related","note":"treatment"},{"target":"Global Task Force on Cholera Control","type":"related","note":"coordination"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.cholera","Wikidata: Q12090 (https://www.wikidata.org/wiki/Q12090)","ICD-10: A00 cholera","ICD-11: 1A00 cholera"]},"properties":{"applicability":"not-applicable","items":["incubation period: about 12 hours to 5 days - per WHO"]},"recognition":{"applicability":"optional","items":["Profuse watery 'rice-water' diarrhoea; diagnosis by clinicians and laboratories"]},"capabilities":{"applicability":"required","items":["explain causes and transmission","explain prevention (water, sanitation, vaccines)","explain treatment principles (rehydration)","point to outbreak information from WHO"]},"hazards":{"applicability":"required","items":["Rapid death from dehydration","Large outbreaks after disasters and conflict"]},"interfaces":{"applicability":"required","items":["International Health Regulations (2005), with notification decided through the Annex 2 assessment","WHO cholera guidelines and Ending Cholera roadmap 2030"]},"context":{"applicability":"required","items":["Vibrio cholerae O1 (classical and El Tor biotypes)","Vibrio cholerae O139","endemic cholera","epidemic cholera"]}},"sources":[{"title":"Q12090","url":"https://www.wikidata.org/wiki/Q12090","note":"identity of the registry item, labels and sitelinks"},{"title":"Cholera","url":"https://en.wikipedia.org/wiki/Cholera","note":"general description of the subject"},{"title":"Cholera","url":"https://www.who.int/news-room/fact-sheets/detail/cholera","note":"Transmission, incubation, symptoms, dehydration, general treatment principles, prevention, vaccination and the 2030 roadmap."},{"title":"Cholera - CDC Yellow Book","url":"https://www.cdc.gov/yellow-book/hcp/travel-associated-infections-diseases/cholera.html","note":"Toxigenic O1 and O139, classical and El Tor biotypes, and distinction from other cholera-like infections."},{"title":"WHO guidance for the use of Annex 2","url":"https://www.who.int/docs/default-source/documents/emergencies/who-guidance-for-use-of-annex-2.pdf","note":"Conditional IHR notification; includes a cholera outbreak example that does not meet notification criteria."},{"title":"National case definition: Cholera","url":"https://www.canada.ca/en/public-health/services/diseases/cholera/professionals/national-case-definition.html","note":"Clinical and laboratory distinctions; ICD-11 1A00 and ICD-10 A00 subcategories."},{"title":"Cholera Outbreak Toolbox","url":"https://www.who.int/emergencies/outbreak-toolkit/disease-outbreak-toolboxes/cholera-outbreak-toolbox","note":"Suspected, probable and confirmed outbreak definitions."},{"title":"Cholera Infantum","url":"https://www.ncbi.nlm.nih.gov/medgen/327988","note":"Separate concept for cholera infantum; supports retaining the draft's merge-review question."}],"openQuestions":["The registry merges cholera infantum, a historical term for infant diarrhoea not caused by Vibrio cholerae; it needs review."],"resources":{"spec":"/models/things/publications/thing-q12090/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q12090/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-10-22T12:45:01Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"not-applicable","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-22T12:54:35+00:00: completeness 1.00; sense: Wikidata description; 8 live sources; review by codex: pass","interaction.properties":"Plane ACT: no invented physical properties."},"score":1.0}}