{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.breast-cancer","code":"thing-q128581","url":"https://ver.cy/models/thing/q128581/","name":"breast cancer","alternateNames":["metastatic cancer to the breast","breast papillary neoplasm","cutaneous breast cancer","metastatic breast cancer","breast malignant phyllodes tumor","non-metastatic breast cancer","early-stage breast cancer","invasive ductal carcinoma","female breast cancer","estrogen-receptor negative breast cancer","progesterone-receptor negative breast cancer","Her2-receptor negative breast cancer"],"kind":"thing","status":"published","version":"0.2.0-wave.2","language":"en","classifiers":{"family":"Thing Registry","category":"Physical world and living systems","entryKind":"thing","plane":"PHY","domain":["PHY.LIV"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"A cancer that forms in the tissues of the breast, most commonly in the ducts or lobules, affecting mainly women but also men, with types ranging from ductal carcinoma in situ to invasive and metastatic disease; it is the most common cancer in women worldwide, detected by screening and symptoms, and treated with surgery, radiotherapy, chemotherapy, hormone and targeted therapies.","purpose":"Let an agent give accurate general information on breast cancer, encourage screening and prompt assessment of changes, explain diagnosis and treatment pathways in general terms, and point to specialist care and support without individual medical advice.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Breast tissue origin","Several subtypes by receptors","Screening-detectable","Hereditary risk in some families"],"structure":{"bundles":[{"id":"symptoms","name":"Symptoms","description":"Changes to check.","layers":[{"id":"changes","name":"Changes","description":"Breast changes.","findings":[{"id":"changes-finding","name":"Changes","description":"Changes.","questions":[{"text":"Has the person noticed a lump, skin change, nipple discharge or other breast change?","kind":"boundary"},{"text":"Should they see a doctor promptly for assessment?","kind":"action"}]}]},{"id":"screening","name":"Screening","description":"Screening programmes.","findings":[{"id":"screening-finding","name":"Screening","description":"Screening.","questions":[{"text":"Who is invited for screening here, at what ages and intervals?","kind":"provenance"},{"text":"What are the benefits and limitations of screening, according to health authorities?","kind":"provenance"}]}]}]},{"id":"understand","name":"Understand","description":"The disease.","layers":[{"id":"types","name":"Types","description":"Types and stages.","findings":[{"id":"types-finding","name":"Types","description":"Types.","questions":[{"text":"What type, subtype and stage is being discussed, in general terms?","kind":"definition"},{"text":"Is the user asking about their own diagnosis or results?","kind":"boundary"}]}]},{"id":"risk","name":"Risk","description":"Risk factors.","findings":[{"id":"risk-finding","name":"Risk","description":"Risk factors.","questions":[{"text":"What do health authorities say about risk factors and hereditary variants?","kind":"provenance"},{"text":"Who is eligible for genetic counselling?","kind":"provenance"}]}]}]},{"id":"treatment","name":"Treatment","description":"Care pathway.","layers":[{"id":"pathway","name":"Pathway","description":"Diagnosis and treatment.","findings":[{"id":"pathway-finding","name":"Pathway","description":"Pathway.","questions":[{"text":"How is breast cancer diagnosed and treated, according to guidelines, in general terms?","kind":"provenance"},{"text":"Which questions should be asked of the oncology team?","kind":"action"}]}]},{"id":"trials","name":"Trials","description":"Clinical trials.","findings":[{"id":"trials-finding","name":"Trials","description":"Trials.","questions":[{"text":"Which trials are recruiting, according to registries?","kind":"provenance"},{"text":"How can a patient discuss trials with their team?","kind":"action"}]}]}]},{"id":"support","name":"Support","description":"Living with it.","layers":[{"id":"orgs","name":"Organisations","description":"Patient groups.","findings":[{"id":"orgs-finding","name":"Organisations","description":"Patient groups.","questions":[{"text":"Which patient organisations support people with breast cancer here, including men?","kind":"provenance"},{"text":"Which services do they offer?","kind":"provenance"}]}]},{"id":"life","name":"Life","description":"After treatment.","findings":[{"id":"life-finding","name":"Life","description":"After treatment.","questions":[{"text":"What follow-up and survivorship support is available?","kind":"provenance"},{"text":"How can carers be supported?","kind":"provenance"}]}]}]}]},"agentConduct":{"may":["Give general information on breast cancer, symptoms, screening and risk factors, citing health sources.","Encourage people with symptoms such as a new lump to see a clinician promptly."],"mustNot":["Diagnose breast cancer in a specific person or predict their prognosis.","Recommend unproven cures or advise against treatment a clinician has offered.","Disclose a person's diagnosis or genetic test results without consent.","Ignore that men can also develop breast cancer."],"requiresHuman":["Treatment decisions.","Sharing genetic risk information with a patient's relatives."]},"ethics":{"considerations":["Breast cancer affects body image, fertility and identity as well as health.","Access to screening and treatment is unequal across countries and groups."],"affectedParties":["Patients","Families and relatives with shared genetic risk","Carers"]},"owners":{"steward":"The patient; their care team answers for diagnosis and treatment.","roles":[],"masterSystems":["Patient health records","National cancer registries"]},"relations":[{"target":"Q18556617","type":"parent","note":"registry parent class"},{"target":"Q23929670","type":"parent","note":"registry parent class"},{"target":"breast neoplasm","type":"related","note":"category"},{"target":"thoracic cancer","type":"related","note":"category"},{"target":"health care","type":"related","note":"services"},{"target":"ovarian cancer","type":"related","note":"shared hereditary risk"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.breast-cancer","Wikidata: Q128581 (https://www.wikidata.org/wiki/Q128581)"]},"properties":{"applicability":"not-applicable","items":[]},"recognition":{"applicability":"required","items":["Breast lumps, skin or nipple changes","Diagnosed by mammography, ultrasound and biopsy","Most breast lumps are benign","Not physical as a concept; a diagnosis from imaging and pathology."]},"capabilities":{"applicability":"required","items":["explain symptoms and screening","describe types and stages in general terms","explain treatment pathways and genetic risk","find specialist centres and patient organisations"]},"hazards":{"applicability":"required","items":["Delayed assessment of symptoms","Agents giving individual medical advice","Unproven treatments"]},"interfaces":{"applicability":"required","items":["Clinical guidelines from oncology societies","National screening programmes","Genetic testing guidelines for BRCA variants"]},"context":{"applicability":"required","items":["A cancer requiring screening, diagnosis, treatment and support.","ductal carcinoma in situ","invasive ductal and lobular carcinoma","hormone receptor positive, HER2 positive and triple negative subtypes","metastatic breast cancer","male breast cancer and rare types such as phyllodes tumours"]}},"sources":[{"title":"Wikidata item Q128581: breast cancer","url":"https://www.wikidata.org/wiki/Q128581","note":"identity and sense of the item"},{"title":"Wikipedia: Breast cancer","url":"https://en.wikipedia.org/wiki/Breast_cancer","note":"general description of the item"}],"openQuestions":["Should each subtype be a separate entry?","How should screening programmes be localised?","How should support organisations be linked?"],"resources":{"spec":"/models/things/publications/thing-q128581/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q128581/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-11T19:39:11Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"not-applicable","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-07T10:10:25+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass","interaction.properties":"Breast cancer is a disease category rather than a physical object or material with shared measurable physical properties."},"score":1.0}}