{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.vaccine","code":"thing-q134808","url":"https://ver.cy/models/thing/q134808/","name":"vaccine","alternateNames":["attenuated vaccine","genetically modified vaccine","Zostavax","Sabin vaccine","M-M-RVAXPRO","M-M-R II","TRIVIVAC","DNA vaccine","V451","vector-based vaccine","Nasal vaccine","Misinformation related to vaccination"],"kind":"thing","status":"published","version":"0.2.0-wave.2","language":"en","classifiers":{"family":"Thing Registry","category":"Physical world and living systems","entryKind":"thing","plane":"PHY","domain":["PHY.OBJ"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"A biological preparation that provides active acquired immunity to a particular infectious disease by exposing the immune system to an antigen, in forms including live attenuated vaccines such as the Sabin oral polio vaccine and measles-mumps-rubella vaccines, inactivated, subunit, toxoid, conjugate, viral vector and nucleic acid vaccines, and genetically engineered vaccines; vaccines are among the most effective public health tools, are licensed and monitored by regulators, and are recommended through immunisation schedules.","purpose":"Let an agent explain vaccines and how they work, describe types and immunisation schedules, relay safety, effectiveness and recommendation information from health authorities and regulators, address misinformation with evidence, and route personal medical questions to clinicians.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Active immunity","Antigen-based","Regulated and monitored","Population-level protection"],"structure":{"bundles":[{"id":"understand","name":"Understand","description":"How vaccines work.","layers":[{"id":"mechanism","name":"Mechanism","description":"Mechanism.","findings":[{"id":"mechanism-finding","name":"Mechanism","description":"Mechanism.","questions":[{"text":"How do vaccines train the immune system, and what is herd immunity?","kind":"definition"},{"text":"Is the user asking about their own vaccination, which needs a clinician?","kind":"boundary"}]}]},{"id":"types","name":"Types","description":"Types.","findings":[{"id":"types-finding","name":"Types","description":"Types.","questions":[{"text":"How do live attenuated, inactivated, subunit, conjugate, vector and nucleic acid vaccines differ?","kind":"definition"},{"text":"Which entry fits a specific vaccine?","kind":"action"}]}]}]},{"id":"use","name":"Use","description":"Schedules and access.","layers":[{"id":"schedules","name":"Schedules","description":"Immunisation schedules.","findings":[{"id":"schedules-finding","name":"Schedules","description":"Schedules.","questions":[{"text":"What do national immunisation schedules recommend for children, adults and travellers, according to health authorities?","kind":"provenance"},{"text":"Is the information current for this jurisdiction?","kind":"boundary"}]}]},{"id":"access","name":"Access","description":"Access.","findings":[{"id":"access-finding","name":"Access","description":"Access.","questions":[{"text":"How can vaccines be obtained, and what programmes support access?","kind":"provenance"},{"text":"Which entry fits immunisation programmes?","kind":"action"}]}]}]},{"id":"safety","name":"Safety","description":"Safety and evidence.","layers":[{"id":"safety","name":"Safety","description":"Safety monitoring.","findings":[{"id":"safety-finding","name":"Safety","description":"Safety.","questions":[{"text":"How are vaccine safety and effectiveness assessed before and after licensing, according to regulators?","kind":"provenance"},{"text":"Which entry fits pharmacovigilance?","kind":"action"}]}]},{"id":"misinformation","name":"Misinformation","description":"Addressing misinformation.","findings":[{"id":"misinformation-finding","name":"Misinformation","description":"Misinformation.","questions":[{"text":"What does evidence say about common vaccine claims, and how do health authorities respond to misinformation?","kind":"provenance"},{"text":"Is the presentation grounded in evidence from authorities?","kind":"boundary"}]}]}]},{"id":"learn","name":"Learn","description":"History and development.","layers":[{"id":"history","name":"History","description":"History.","findings":[{"id":"history-finding","name":"History","description":"History.","questions":[{"text":"How did vaccines develop from Jenner and Pasteur to modern platforms, and what diseases have been controlled?","kind":"provenance"},{"text":"Which references are standard?","kind":"provenance"}]}]},{"id":"development","name":"Development","description":"Development and manufacturing.","findings":[{"id":"development-finding","name":"Development","description":"Development.","questions":[{"text":"How are vaccines developed, tested and manufactured?","kind":"provenance"},{"text":"Which misconceptions arise?","kind":"provenance"}]}]}]}]},"agentConduct":{"may":["Explain how vaccines work and how they are tested and approved, with sources.","Direct people to their health service or clinician for vaccination advice."],"mustNot":["Give personal advice on whether a person should be vaccinated.","Spread or amplify vaccine misinformation.","Downplay or exaggerate known side effects.","Disclose a person's vaccination status without consent."],"requiresHuman":["Any decision on administering a vaccine to a person."]},"ethics":{"considerations":["Vaccines protect communities, and misinformation costs lives.","Rare side effects are real and deserve honesty."],"affectedParties":["Children","Immunocompromised people","The public"]},"owners":{"steward":"The authorisation holder; medicines regulators approve vaccines.","roles":[],"masterSystems":["National immunisation registers"]},"relations":[{"target":"Q12140","type":"parent","note":"registry parent class"},{"target":"Q679692","type":"parent","note":"registry parent class"},{"target":"medication","type":"related","note":"category"},{"target":"biopharmaceutical","type":"related","note":"category"},{"target":"innate immune response","type":"related","note":"immune mechanisms engaged"},{"target":"pathogen","type":"related","note":"targets of vaccines"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.vaccine","Wikidata: Q134808 (https://www.wikidata.org/wiki/Q134808)"]},"properties":{"applicability":"required","items":["Liquid fill volume:  mL - Measure the liquid volume in a container and distinguish it from the labeled administration volume.","Storage temperature:  degrees Celsius - Measure product storage conditions with a calibrated temperature monitor and compare them with the product-specific label.","pH:  dimensionless - Measure a liquid formulation using a validated method appropriate to the specific product."]},"recognition":{"applicability":"required","items":["Induces active immunity by antigen exposure","Live, inactivated, subunit, vector, nucleic acid","Antibody treatments give passive immunity; antibiotics treat bacterial infection","Injectable, oral or nasal preparations in vials and doses."]},"capabilities":{"applicability":"required","items":["explain how vaccines work","describe types and schedules","relay safety and effectiveness information","route personal questions"]},"hazards":{"applicability":"required","items":["Misinformation reducing uptake","Agents giving personal medical advice","Rare adverse events, which are monitored"]},"interfaces":{"applicability":"required","items":["Vaccine licensing and pharmacovigilance by regulators","National immunisation schedules","Manufacturing quality standards"]},"context":{"applicability":"required","items":["Preparations that induce immunity to disease.","live attenuated vaccines","inactivated and toxoid vaccines","subunit and conjugate vaccines","viral vector and nucleic acid vaccines","combination vaccines such as measles-mumps-rubella"]}},"sources":[{"title":"Wikidata item Q134808: vaccine","url":"https://www.wikidata.org/wiki/Q134808","note":"identity and sense of the item"},{"title":"Wikipedia: Vaccine","url":"https://en.wikipedia.org/wiki/Vaccine","note":"general description of the item"}],"openQuestions":["Should each vaccine be a separate entry?","How should health authorities be linked by country?","How should safety monitoring data be linked?"],"resources":{"spec":"/models/things/publications/thing-q134808/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q134808/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-12T03:42:38Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"filled","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-07T10:10:26+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass"},"score":1.0}}