{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.segmentation","code":"thing-q1423946","url":"https://ver.cy/models/thing/q1423946/","name":"segmentation","alternateNames":["somitogenesis","blastoderm segmentation","renal system segmentation","brain segmentation","trunk segmentation","central nervous system segmentation","appendage segmentation","insect antenna","Compartment"],"kind":"thing","status":"published","version":"0.2.0-wave.3","language":"en","classifiers":{"family":"Thing Registry","category":"Activities and processes","entryKind":"thing","plane":"ACT","domain":["ACT.PRC"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"In developmental biology, the division of a body or organ into repeated units along an axis, as in somitogenesis forming somites in vertebrate embryos, trunk segmentation in arthropods and annelids, blastoderm segmentation controlled by gap, pair-rule and segment polarity genes in Drosophila, and segmentation of the brain and central nervous system into neuromeres; the word is also used for image segmentation and market segmentation, separate senses noted here only for routing.","purpose":"Let an agent explain biological segmentation and its mechanisms, relay research on somitogenesis, arthropod segmentation and neural segmentation with attribution, describe its evolutionary significance, and route non-biological senses to their own entries.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Repeated units along an axis","Genetic control","Clock and wavefront in vertebrates","Contested evolutionary origin"],"structure":{"bundles":[{"id":"understand","name":"Understand","description":"What segmentation is.","layers":[{"id":"definition","name":"Definition","description":"Definition and examples.","findings":[{"id":"definition-finding","name":"Definition","description":"Definition.","questions":[{"text":"What is segmentation in development, and where does it occur?","kind":"definition"},{"text":"Is the question about biological, image or market segmentation?","kind":"boundary"}]}]},{"id":"mechanisms","name":"Mechanisms","description":"Mechanisms.","findings":[{"id":"mechanisms-finding","name":"Mechanisms","description":"Mechanisms.","questions":[{"text":"How do the clock and wavefront in somitogenesis and the gene hierarchy in Drosophila control segmentation?","kind":"definition"},{"text":"Which entry fits the specific mechanism?","kind":"action"}]}]}]},{"id":"systems","name":"Systems","description":"Systems.","layers":[{"id":"vertebrates","name":"Vertebrates","description":"Vertebrate segmentation.","findings":[{"id":"vertebrates-finding","name":"Vertebrates","description":"Vertebrates.","questions":[{"text":"How do somites and neuromeres form in vertebrates, as research shows?","kind":"provenance"},{"text":"Which entry fits somite?","kind":"action"}]}]},{"id":"invertebrates","name":"Invertebrates","description":"Arthropods and annelids.","findings":[{"id":"invertebrates-finding","name":"Invertebrates","description":"Invertebrates.","questions":[{"text":"How does segmentation work in arthropods and annelids?","kind":"provenance"},{"text":"Which references are standard?","kind":"provenance"}]}]}]},{"id":"evolution","name":"Evolution","description":"Evolution.","layers":[{"id":"origins","name":"Origins","description":"Evolutionary origins.","findings":[{"id":"origins-finding","name":"Origins","description":"Origins.","questions":[{"text":"Did segmentation evolve once or several times, and what do researchers argue, with positions attributed?","kind":"provenance"},{"text":"Is the presentation attributed?","kind":"boundary"}]}]},{"id":"disease","name":"Disease","description":"Defects.","findings":[{"id":"disease-finding","name":"Disease","description":"Disease.","questions":[{"text":"What developmental defects arise from segmentation errors, in general terms?","kind":"provenance"},{"text":"Which sources are cited?","kind":"provenance"}]}]}]},{"id":"context","name":"Context","description":"Methods and history.","layers":[{"id":"methods","name":"Methods","description":"Methods.","findings":[{"id":"methods-finding","name":"Methods","description":"Methods.","questions":[{"text":"How is segmentation studied with live imaging, genetics and modelling?","kind":"provenance"},{"text":"Which entry fits developmental biology methods?","kind":"action"}]}]},{"id":"history","name":"History","description":"History.","findings":[{"id":"history-finding","name":"History","description":"History.","questions":[{"text":"How did the discovery of segmentation genes, recognised by the 1995 Nobel Prize, transform the field?","kind":"provenance"},{"text":"Which entry fits the history of developmental biology?","kind":"action"}]}]}]}]},"agentConduct":{"may":["Explain segmentation in development and its genetic control from biological sources.","Analyse embryonic imaging or expression data a researcher is authorized to use."],"mustNot":["Present developmental findings as medical advice about a pregnancy.","Interpret a person's prenatal scan or genetic result as a clinician.","Work with human embryos or embryo models outside the approved research framework.","Fabricate or selectively report developmental data."],"requiresHuman":["Any research step involving human embryos or reproductive decisions."]},"ethics":{"considerations":["Human embryo research is permitted only within strict ethical limits and oversight.","Findings about developmental defects reach frightened parents and must not be overstated."],"affectedParties":["Research participants and donors","Prospective parents","Laboratory animals"]},"owners":{"steward":"Nobody owns a biological process; research ethics committees oversee work on it.","roles":[],"masterSystems":[]},"relations":[{"target":"Q22271259","type":"parent","note":"registry parent class"},{"target":"regionalization","type":"related","note":"in registry terms"},{"target":"somite","type":"related","note":"in vertebrates"},{"target":"segmentation gene","type":"related","note":"such as pair-rule genes"},{"target":"image segmentation","type":"related","note":"a computing sense"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.segmentation","Wikidata: Q1423946 (https://www.wikidata.org/wiki/Q1423946)","Gene Ontology: GO:0035282 segmentation"]},"properties":{"applicability":"not-applicable","items":["human somite pairs: about 42-44 count - in the embryo"]},"recognition":{"applicability":"optional","items":["Division of the body into repeated units","Somites, arthropod segments, neuromeres","Image segmentation and market segmentation are unrelated senses","Repeated body units visible in embryos and adult animals such as earthworms and insects."]},"capabilities":{"applicability":"required","items":["explain the process and mechanisms","relay research","describe evolutionary significance","route other senses"]},"hazards":{"applicability":"required","items":["Confusing senses of segmentation","Presenting contested homology as settled","Overgeneralising between animal groups"]},"interfaces":{"applicability":"required","items":["No regulation; research standards"]},"context":{"applicability":"required","items":["Not applicable; a developmental process.","somitogenesis in vertebrates","segmentation in arthropods including Drosophila blastoderm segmentation","segmentation in annelids","segmentation of the brain and central nervous system","segmentation of the renal system and other organs","segmentation in imaging and marketing as separate senses"]}},"sources":[{"title":"Wikidata item Q1423946: segmentation","url":"https://www.wikidata.org/wiki/Q1423946","note":"identity and sense of the item"},{"title":"Wikipedia: Segmentation (biology)","url":"https://en.wikipedia.org/wiki/Segmentation_%28biology%29","note":"general description of the item"}],"openQuestions":["Should somitogenesis be a separate primary entry?","How should developmental biology references be linked?","The registry entry has merged aliases naming organ-specific processes; should they be split off?"],"resources":{"spec":"/models/things/publications/thing-q1423946/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q1423946/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-13T01:10:31Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"not-applicable","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-06T19:51:54+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass","interaction.properties":"Plane ACT: no invented physical properties."},"score":1.0}}