{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.immune-response","code":"thing-q1612119","url":"https://ver.cy/models/thing/q1612119/","name":"immune response","alternateNames":[],"kind":"thing","status":"research-draft","version":"0.2.0-wave.1","language":"en","classifiers":{"family":"Thing Registry","category":"","entryKind":"","plane":"","domain":["ACT.PRC"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"The reaction of the immune system to a foreign substance, pathogen or altered self, involving innate and adaptive components such as inflammation, antibodies and T cells; responses can be protective, as after vaccination, or harmful, as in allergies, autoimmunity and cytokine storms.","purpose":"Let an agent explain immune responses in general terms, route severe allergic reactions to emergency help, and point to vaccination and health information, without personal medical advice.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Reaction to foreign or altered material","Innate and adaptive arms","Can be protective or harmful","Has memory in adaptive immunity"],"structure":{"bundles":[{"id":"emergency","name":"Emergency","description":"Severe reactions.","layers":[{"id":"anaphylaxis","name":"Anaphylaxis","description":"Severe allergy.","findings":[{"id":"anaphylaxis-finding","name":"Anaphylaxis","description":"Anaphylaxis.","questions":[{"text":"Is someone having difficulty breathing, swelling of the face or throat, or collapsing after exposure?","kind":"boundary"},{"text":"Should emergency services be called and an adrenaline auto-injector used if available?","kind":"action"}]}]},{"id":"sepsis","name":"Sepsis","description":"Severe infection.","findings":[{"id":"sepsis-finding","name":"Sepsis","description":"Sepsis signs.","questions":[{"text":"Are there signs of sepsis such as confusion, fast breathing or mottled skin?","kind":"boundary"},{"text":"Should urgent medical help be sought now?","kind":"action"}]}]}]},{"id":"biology","name":"Biology","description":"How it works.","layers":[{"id":"innate","name":"Innate","description":"Innate immunity.","findings":[{"id":"innate-finding","name":"Innate","description":"Innate immunity.","questions":[{"text":"How does the innate immune system respond quickly to threats?","kind":"definition"},{"text":"What role does inflammation play?","kind":"definition"}]}]},{"id":"adaptive","name":"Adaptive","description":"Adaptive immunity.","findings":[{"id":"adaptive-finding","name":"Adaptive","description":"Adaptive immunity.","questions":[{"text":"How do antibodies and T cells create targeted responses and memory?","kind":"definition"},{"text":"How long does memory last, according to research?","kind":"provenance"}]}]}]},{"id":"vaccines","name":"Vaccines","description":"Protective responses.","layers":[{"id":"how","name":"How","description":"Vaccine responses.","findings":[{"id":"how-finding","name":"How","description":"Vaccine responses.","questions":[{"text":"How do vaccines train the immune system, according to health authorities?","kind":"provenance"},{"text":"Which side effects are common?","kind":"provenance"}]}]},{"id":"schedule","name":"Schedule","description":"Vaccination schedules.","findings":[{"id":"schedule-finding","name":"Schedule","description":"Vaccination schedules.","questions":[{"text":"Which vaccinations are recommended here, according to the national schedule?","kind":"provenance"},{"text":"Is the user asking whether they personally should be vaccinated?","kind":"boundary"}]}]}]},{"id":"disorders","name":"Disorders","description":"Harmful responses.","layers":[{"id":"allergy","name":"Allergy","description":"Allergies.","findings":[{"id":"allergy-finding","name":"Allergy","description":"Allergies.","questions":[{"text":"What do health services say about allergies and how they are diagnosed?","kind":"provenance"},{"text":"Where can allergy testing be accessed?","kind":"provenance"}]}]},{"id":"autoimmunity","name":"Autoimmunity","description":"Autoimmune disease.","findings":[{"id":"autoimmunity-finding","name":"Autoimmunity","description":"Autoimmune disease.","questions":[{"text":"What happens in autoimmune diseases, in general terms?","kind":"definition"},{"text":"Is the user asking about their own condition?","kind":"boundary"}]}]}]}]},"agentConduct":{"may":["explain innate and adaptive immunity","recognise severe allergic reactions","understand how vaccines trigger immune responses","find reliable health information"],"mustNot":[],"requiresHuman":[]},"ethics":{"considerations":["The reaction of the immune system to a foreign substance, pathogen or altered self, involving innate and adaptive components such as inflammation, antibodies and T cells; responses can be protective, as after vaccination, or harmful, as in allergies, autoimmunity and cytokine storms.","Can be protective or harmful"],"affectedParties":[]},"owners":{"steward":"","roles":[],"masterSystems":[]},"relations":[{"target":"response to stimulus","type":"related","note":"category"},{"target":"immune system process","type":"related","note":"process"},{"target":"vaccination","type":"related","note":"intervention"},{"target":"response","type":"related","note":"general concept"}],"interaction":{"identity":{"applicability":"required","items":[]},"properties":{"applicability":"not-applicable","items":[]},"recognition":{"applicability":"optional","items":["Inflammation and fever","Antibody and cell assays","Symptoms can also come from the pathogen itself","Not directly visible; shown in inflammation, fever, antibody tests and immune cell studies."]},"capabilities":{"applicability":"required","items":["explain innate and adaptive immunity","recognise severe allergic reactions","understand how vaccines trigger immune responses","find reliable health information"]},"hazards":{"applicability":"required","items":["Missing anaphylaxis","Vaccine misinformation","Agents giving personal medical advice"]},"interfaces":{"applicability":"required","items":["WHO vaccine guidance","Allergen labelling rules","Clinical guidelines on anaphylaxis"]},"context":{"applicability":"required","items":["Defence against infection and disease.","innate immune responses","adaptive antibody and T cell responses","allergic and hypersensitivity reactions","autoimmune responses","systemic responses such as cytokine storms"]}},"sources":[],"openQuestions":["Should response types be separate entries?","How should immunology resources be linked?","How should vaccine information be localised?","Should emergency services be called and an adrenaline auto-injector used if available?","Should urgent medical help be sought now?"],"resources":{"spec":"/models/things/publications/thing-q1612119/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q1612119/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-11T15:11:43Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"derived","ethics":"derived","owners":"missing","relations":"filled","interaction.identity":"missing","interaction.properties":"not-applicable","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"missing"},"notes":{"agentConduct":"Affordances listed as what may be done; prohibitions collected from the text.","interaction.properties":"Plane ACT: no invented physical properties.","sources":"Written from model knowledge without web access; claims are unverified."},"score":0.75}}