{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.cranial-nerve-nucleus","code":"thing-q1620205","url":"https://ver.cy/models/thing/q1620205/","name":"cranial nerve nucleus","alternateNames":["principal sensory nucleus of trigeminal nerve","principal sensory nucleus of right trigeminal nerve","principal sensory nucleus of left trigeminal nerve","facial motor nucleus","abducens nucleus","Trochlear nucleus","terminal nucleus of cranial nerve","vagus nerve nucleus","interfascicular nucleus of hypoglossal nerve","vestibular nucleus","cochlear nucleus","segment of spinal nucleus of trigeminal nerve"],"kind":"thing","status":"published","version":"0.2.0-wave.4","language":"en","classifiers":{"family":"Thing Registry","category":"Physical world and living systems","entryKind":"thing","plane":"PHY","domain":["PHY.LIV"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"A cranial nerve nucleus is a collection of neurons in the brainstem associated with one or more cranial nerves, receiving sensory information or providing motor output according to its connections and function.","purpose":"Let an agent explain cranial nerve nuclei, their brainstem locations, functions and cranial nerve connections, describe clinical significance in general terms, and distinguish these neuron collections from cranial nerves and from individual examples such as the nucleus ambiguus.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Cranial nerve nuclei are collections of neuronal cell bodies in the brainstem.","Their functions include sensory processing, control of skeletal muscles and parasympathetic motor output.","Many cranial nerve nuclei have corresponding left and right instances.","A nucleus may be associated with more than one cranial nerve, and a cranial nerve may be associated with more than one nucleus.","Damage can produce signs relevant to clinical localisation."],"structure":{"bundles":[{"id":"understand","name":"Understand","description":"What a cranial nerve nucleus is.","layers":[{"id":"definition","name":"Definition","description":"Definition.","findings":[{"id":"definition-finding","name":"Definition","description":"Definition.","questions":[{"text":"Is someone showing sudden facial droop, double vision, slurred speech or weakness, in which case call emergency services for possible stroke?","kind":"boundary"},{"text":"What is a cranial nerve nucleus, and how does it differ from cranial nerves, basal ganglia, thalamic nuclei and spinal nuclei?","kind":"definition"}]}]},{"id":"nuclei","name":"Nuclei","description":"Named nuclei.","findings":[{"id":"nuclei-finding","name":"Nuclei","description":"Nuclei.","questions":[{"text":"What do the facial motor, abducens, trochlear and principal trigeminal sensory nuclei do?","kind":"definition"},{"text":"Which entry fits the specific nucleus?","kind":"action"}]}]}]},{"id":"anatomy","name":"Anatomy","description":"Anatomy.","layers":[{"id":"columns","name":"Columns","description":"Functional columns.","findings":[{"id":"columns-finding","name":"Columns","description":"Columns.","questions":[{"text":"How are nuclei organised into functional columns?","kind":"provenance"},{"text":"Which references are standard?","kind":"provenance"}]}]},{"id":"locations","name":"Locations","description":"Brainstem locations.","findings":[{"id":"locations-finding","name":"Locations","description":"Locations.","questions":[{"text":"Where are nuclei located in the midbrain, pons and medulla?","kind":"provenance"},{"text":"Which sources are cited?","kind":"provenance"}]}]}]},{"id":"clinical","name":"Clinical","description":"Clinical significance.","layers":[{"id":"lesions","name":"Lesions","description":"Brainstem lesions.","findings":[{"id":"lesions-finding","name":"Lesions","description":"Lesions.","questions":[{"text":"How do lesions of specific nuclei produce localising signs?","kind":"provenance"},{"text":"Which entry fits brainstem stroke syndrome?","kind":"action"}]}]},{"id":"eyes","name":"Eye movements","description":"Eye movement nuclei.","findings":[{"id":"eyes-finding","name":"Eye movements","description":"Eye movements.","questions":[{"text":"How do the oculomotor, trochlear and abducens nuclei coordinate gaze?","kind":"provenance"},{"text":"Is the information accurate?","kind":"boundary"}]}]}]},{"id":"context","name":"Context","description":"Data.","layers":[{"id":"ontology","name":"Ontology","description":"Anatomy ontologies.","findings":[{"id":"ontology-finding","name":"Ontology","description":"Ontology.","questions":[{"text":"How do ontologies handle left and right anatomical instances?","kind":"provenance"},{"text":"Which entry fits Foundational Model of Anatomy?","kind":"action"}]}]},{"id":"imaging","name":"Imaging","description":"Imaging.","findings":[{"id":"imaging-finding","name":"Imaging","description":"Imaging.","questions":[{"text":"How are brainstem nuclei studied with MRI?","kind":"provenance"},{"text":"Is the information current?","kind":"boundary"}]}]}]}]},"agentConduct":{"may":["Describe cranial nerve nuclei and their functions from anatomy sources.","Help students learn the locations and connections of individual cranial nerve nuclei.","Explain in general terms what symptoms damage can cause."],"mustNot":["Diagnose brainstem damage in a particular person from their symptoms.","Interpret a person's brain scan or neurological exam.","Present simplified teaching diagrams as exact anatomy.","Give advice that delays emergency care for sudden facial weakness or double vision.","Equate the nucleus ambiguus with cranial nerve nuclei generally."],"requiresHuman":["Any clinical decision based on brainstem anatomy for a patient requires a qualified human clinician."]},"ethics":{"considerations":["Sudden neurological symptoms can signal stroke, where delay costs function or life.","Teaching errors in neuroanatomy carry into clinical practice."],"affectedParties":["Patients with neurological symptoms","Medical students","Clinicians"]},"owners":{"steward":"Nobody owns the anatomy; it is held in common by medicine.","roles":[],"masterSystems":[]},"relations":[{"target":"Q66590385","type":"parent","note":"registry parent class"},{"target":"nucleus of brain","type":"related","note":"in registry terms"},{"target":"brainstem","type":"related"},{"target":"abducens nucleus","type":"related"},{"target":"cranial nerve","type":"related"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.cranial-nerve-nucleus","Wikidata: Q1620205 (https://www.wikidata.org/wiki/Q1620205)"]},"properties":{"applicability":"required","items":["cranial nerves: 12 pairs","brainstem divisions: midbrain, pons, medulla list","abducens nucleus location: pons note"]},"recognition":{"applicability":"required","items":["Anatomical diagrams depict cranial nerve nuclei as neuron collections at different locations within the brainstem.","Labels, anatomical landmarks and depicted nerve connections support identification of individual nuclei.","The nucleus ambiguus is one example alongside facial, abducens, trochlear and trigeminal nuclei.","Grey matter clusters in the midbrain, pons and medulla, seen in brainstem sections."]},"capabilities":{"applicability":"required","items":["explain types and locations","relay functions","describe named nuclei","route stroke signs"]},"hazards":{"applicability":"required","items":["Failure to recognise sudden neurological symptoms can delay emergency care.","Left and right instances must not be treated as different kinds of nucleus.","Simplified functional maps can misrepresent cranial nerve nuclei.","Confusing a nucleus with a cranial nerve misrepresents the relationship between neuronal cell bodies and nerve fibres.","Treating the nucleus ambiguus as synonymous with all cranial nerve nuclei misrepresents the supplied sense."]},"interfaces":{"applicability":"required","items":["Terminologia Neuroanatomica"]},"context":{"applicability":"required","items":["Sensory and motor processing for cranial nerves.","general somatic efferent nuclei","special visceral efferent nuclei","general visceral efferent nuclei","sensory nuclei"]}},"sources":[{"title":"Wikidata item Q1620205: cranial nerve nucleus","url":"https://www.wikidata.org/wiki/Q1620205","note":"identity and sense of the item"},{"title":"Wikipedia: Cranial nerve nucleus","url":"https://en.wikipedia.org/wiki/Cranial_nerve_nucleus","note":"general description of the item"}],"openQuestions":["The registry left and right aliases should be treated as paired instances","Should each nucleus be a separate entry?","How should anatomy ontologies be linked?"],"resources":{"spec":"/models/things/publications/thing-q1620205/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q1620205/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-14T01:19:29Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"filled","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-09T07:29:59+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass"},"score":1.0}}