{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.connective-tissue-disease","code":"thing-q1779300","url":"https://ver.cy/models/thing/q1779300/","name":"connective tissue disease","alternateNames":["Stromal tumor","lipomatous cancer","connective tissue neoplasm","Stromal tumor, benign","benign pleural mesothelioma","cartilage cancer","connective tissue benign neoplasm","mesenchymoma","hypothalamic neoplasm","pleural cancer","adult intracranial malignant hemangiopericytoma","Inverse Klippel-Trenaunay syndrome"],"kind":"thing","status":"published","version":"0.2.0-wave.1","language":"en","classifiers":{"family":"Thing Registry","category":"Cross-cutting context","entryKind":"thing","plane":"XCT","domain":["XCT.STA"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"A disease affecting connective tissues, which support and connect other tissues and organs, including autoimmune conditions such as lupus and systemic sclerosis, heritable disorders such as Ehlers-Danlos and Marfan syndromes, and tumours of connective tissue such as sarcomas.","purpose":"Let an agent explain connective tissue diseases in general terms and point to specialist care and patient organisations, without diagnosis or personal medical advice.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Affects supporting tissues","Very diverse causes","Often chronic","Requires specialist assessment"],"structure":{"bundles":[{"id":"urgent","name":"Urgent","description":"Serious symptoms.","layers":[{"id":"signs","name":"Signs","description":"Urgent signs.","findings":[{"id":"signs-finding","name":"Signs","description":"Urgent signs.","questions":[{"text":"Are there severe symptoms such as chest pain, breathlessness or sudden weakness?","kind":"boundary"},{"text":"Which emergency service should be contacted?","kind":"action"}]}]},{"id":"diagnosis","name":"Diagnosis","description":"Clinicians.","findings":[{"id":"diagnosis-finding","name":"Diagnosis","description":"Diagnosis limit.","questions":[{"text":"Is the user asking the agent to diagnose a condition?","kind":"boundary"},{"text":"How should they be referred to a clinician?","kind":"action"}]}]}]},{"id":"categories","name":"Categories","description":"General information.","layers":[{"id":"types","name":"Types","description":"Groups.","findings":[{"id":"types-finding","name":"Types","description":"Types.","questions":[{"text":"Which group of connective tissue disease is being discussed?","kind":"definition"},{"text":"Which reliable sources describe it?","kind":"provenance"}]}]},{"id":"genetics","name":"Genetics","description":"Heritable disorders.","findings":[{"id":"genetics-finding","name":"Genetics","description":"Heritable disorders.","questions":[{"text":"Is the condition inherited, in general terms?","kind":"provenance"},{"text":"Is genetic counselling available?","kind":"provenance"}]}]}]},{"id":"care","name":"Care","description":"Services.","layers":[{"id":"specialists","name":"Specialists","description":"Referral.","findings":[{"id":"specialists-finding","name":"Specialists","description":"Specialist care.","questions":[{"text":"Which specialist service manages this condition here?","kind":"provenance"},{"text":"How is a referral made?","kind":"action"}]}]},{"id":"treatments","name":"Treatments","description":"Evidence.","findings":[{"id":"treatments-finding","name":"Treatments","description":"Treatments.","questions":[{"text":"Which treatments are recommended by clinical guidelines, in general terms?","kind":"provenance"},{"text":"Are unproven treatments being promoted?","kind":"boundary"}]}]}]},{"id":"living","name":"Living","description":"Support.","layers":[{"id":"organisations","name":"Organisations","description":"Patient groups.","findings":[{"id":"organisations-finding","name":"Organisations","description":"Patient organisations.","questions":[{"text":"Which patient organisations support people with this condition?","kind":"provenance"},{"text":"What resources do they offer?","kind":"provenance"}]}]},{"id":"work","name":"Work","description":"Adjustments.","findings":[{"id":"work-finding","name":"Work","description":"Work and school.","questions":[{"text":"What adjustments or rights apply at work or school?","kind":"provenance"},{"text":"Who can advise?","kind":"provenance"}]}]}]}]},"agentConduct":{"may":["Explain connective tissue diseases in general terms from reliable medical sources.","Help a patient keep a record of symptoms and appointments they choose to share."],"mustNot":["Diagnose a connective tissue disease or rule one out for a specific person.","Recommend starting, stopping or changing immunosuppressive or other treatment.","Promote unproven cures to people with chronic autoimmune illness.","Disclose a person's diagnosis to employers, insurers or others without consent."],"requiresHuman":["Any treatment decision, which belongs to the patient and their clinician."]},"ethics":{"considerations":["These diseases are often invisible and slow to diagnose, so patients are disbelieved or dismissed.","Lupus and similar conditions affect women and some ethnic groups more, raising equity concerns in care."],"affectedParties":["Patients","Their families and carers","Clinicians"]},"owners":{"steward":"The patient, with the treating clinician; health records are held by the care provider.","roles":[],"masterSystems":["Patient health records","Disease registries"]},"relations":[{"target":"Q4116663","type":"parent","note":"registry parent class"},{"target":"Q54943763","type":"parent","note":"registry parent class"},{"target":"musculoskeletal disorder","type":"related","note":"category"},{"target":"connective tissue","type":"related","note":"tissue"},{"target":"rheumatology and genetics services","type":"related","note":"care"},{"target":"systemic lupus erythematosus","type":"related","note":"example"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.connective-tissue-disease","Wikidata: Q1779300 (https://www.wikidata.org/wiki/Q1779300)","ICD-11: multiple codes across chapters classification"]},"properties":{"applicability":"not-applicable","items":[]},"recognition":{"applicability":"optional","items":["Autoimmune, heritable and neoplastic groups","Specialties such as rheumatology and genetics","Many conditions need specialist diagnosis","Signs vary widely, from joint and skin changes to internal organ involvement."]},"capabilities":{"applicability":"required","items":["explain categories in general terms","find specialist services such as rheumatology","find patient support organisations","recognise when urgent care is needed"]},"hazards":{"applicability":"required","items":["Agents diagnosing conditions","Delaying care for serious symptoms","Unproven treatments"]},"interfaces":{"applicability":"required","items":["Clinical classification criteria","Rare disease policies"]},"context":{"applicability":"required","items":["A broad health category relevant to rheumatology, genetics and oncology.","autoimmune connective tissue diseases","heritable connective tissue disorders","soft tissue and bone tumours","mixed and overlap conditions"]}},"sources":[{"title":"Wikidata item Q1779300: connective tissue disease","url":"https://www.wikidata.org/wiki/Q1779300","note":"identity and sense of the item"},{"title":"Wikipedia: Connective tissue disease","url":"https://en.wikipedia.org/wiki/Connective_tissue_disease","note":"general description of the item"}],"openQuestions":["Should each disease be a separate entry?","How should patient organisations be localised?","How should alias lists be curated?"],"resources":{"spec":"/models/things/publications/thing-q1779300/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q1779300/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-11T10:31:22Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"not-applicable","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-06T19:51:55+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass","interaction.properties":"Plane XCT: no invented physical properties."},"score":1.0}}