{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.carbohydrate-metabolic-process","code":"thing-q2734081","url":"https://ver.cy/models/thing/q2734081/","name":"carbohydrate metabolic process","alternateNames":["carbohydrate biosynthetic process","cellular carbohydrate metabolic process","monosaccharide metabolic process","Lewis x epitope biosynthetic process","oligosaccharide metabolic process","polysaccharide metabolic process","carbohydrate catabolic process","aldaric acid metabolic process","starch digestion"],"kind":"thing","status":"published","version":"0.2.0-wave.3","language":"en","classifiers":{"family":"Thing Registry","category":"Activities and processes","entryKind":"thing","plane":"ACT","domain":["ACT.PRC"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"The set of chemical reactions by which cells synthesise, interconvert and break down carbohydrates, including monosaccharide metabolism such as glycolysis and gluconeogenesis, oligosaccharide and polysaccharide metabolism such as glycogen and starch synthesis and breakdown, the pentose phosphate pathway, and the biosynthesis of glycan structures such as the Lewis x epitope on glycoproteins and glycolipids; carbohydrate metabolism supplies energy and building blocks and is regulated by hormones such as insulin and glucagon, with disorders including diabetes and inherited enzyme deficiencies.","purpose":"Let an agent explain carbohydrate metabolism and its main pathways, relay enzymes, regulation and disorders from biochemistry and clinical references, describe glycan biosynthesis, and distinguish carbohydrate metabolism from lipid and protein metabolism and from dietary carbohydrate topics.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Glucose hub","Anabolic and catabolic arms","Hormonal regulation","Glycan structures"],"structure":{"bundles":[{"id":"understand","name":"Understand","description":"What carbohydrate metabolism is.","layers":[{"id":"definition","name":"Definition","description":"Definition.","findings":[{"id":"definition-finding","name":"Definition","description":"Definition.","questions":[{"text":"What is carbohydrate metabolism, and how does it differ from lipid and protein metabolism and from dietary carbohydrate topics?","kind":"definition"},{"text":"Is the question about the process in general, a pathway, a disorder or diet?","kind":"boundary"}]}]},{"id":"pathways","name":"Pathways","description":"Pathways.","findings":[{"id":"pathways-finding","name":"Pathways","description":"Pathways.","questions":[{"text":"How do glycolysis, gluconeogenesis, the pentose phosphate pathway, glycogen metabolism and glycan biosynthesis work?","kind":"definition"},{"text":"Which entry fits the specific pathway?","kind":"action"}]}]}]},{"id":"regulation","name":"Regulation","description":"Regulation.","layers":[{"id":"hormones","name":"Hormones","description":"Hormonal control.","findings":[{"id":"hormones-finding","name":"Hormones","description":"Hormones.","questions":[{"text":"How do insulin, glucagon and other signals regulate blood glucose and storage?","kind":"provenance"},{"text":"Which references are standard?","kind":"provenance"}]}]},{"id":"tissues","name":"Tissues","description":"Tissues.","findings":[{"id":"tissues-finding","name":"Tissues","description":"Tissues.","questions":[{"text":"How do liver, muscle, brain and adipose tissue differ in carbohydrate metabolism?","kind":"provenance"},{"text":"Which sources are cited?","kind":"provenance"}]}]}]},{"id":"medicine","name":"Medicine","description":"Disorders.","layers":[{"id":"diabetes","name":"Diabetes","description":"Diabetes.","findings":[{"id":"diabetes-finding","name":"Diabetes","description":"Diabetes.","questions":[{"text":"How does diabetes disrupt carbohydrate metabolism, in general terms?","kind":"provenance"},{"text":"Is the user asking about their own condition, which needs a clinician?","kind":"boundary"}]}]},{"id":"inherited","name":"Inherited","description":"Inherited disorders.","findings":[{"id":"inherited-finding","name":"Inherited","description":"Inherited.","questions":[{"text":"What are glycogen storage diseases, galactosaemia and other inherited disorders, in general terms?","kind":"provenance"},{"text":"Which entry fits the specific disorder?","kind":"action"}]}]}]},{"id":"context","name":"Context","description":"Glycans and history.","layers":[{"id":"glycans","name":"Glycans","description":"Glycan biosynthesis.","findings":[{"id":"glycans-finding","name":"Glycans","description":"Glycans.","questions":[{"text":"How are glycan structures such as the Lewis x epitope built, and what roles do they play?","kind":"provenance"},{"text":"Which entry fits glycobiology?","kind":"action"}]}]},{"id":"history","name":"History","description":"History.","findings":[{"id":"history-finding","name":"History","description":"History.","questions":[{"text":"How were glycolysis and glycogen metabolism discovered, from Buchner to the Coris and Krebs?","kind":"provenance"},{"text":"Which entry fits the history of biochemistry?","kind":"action"}]}]}]}]},"agentConduct":{"may":["Explain carbohydrate metabolic pathways such as glycolysis and gluconeogenesis from biochemistry sources.","Distinguish cellular metabolism from dietary carbohydrate topics."],"mustNot":["Give personal dietary or medical advice based on metabolic pathways.","Oversimplify metabolic regulation into diet claims.","Present preliminary research as clinical guidance."],"requiresHuman":["Any treatment decision for metabolic disease."]},"ethics":{"considerations":["Metabolic science is often misused to sell diets.","People with metabolic disease need accurate, clinician-led advice."],"affectedParties":["People with diabetes or metabolic disorders","Students","Consumers"]},"owners":{"steward":"Nobody owns the process; biological databases record pathway knowledge.","roles":[],"masterSystems":["Gene ontology and pathway databases"]},"relations":[{"target":"Q19708902","type":"parent","note":"registry parent class"},{"target":"Q21149516","type":"parent","note":"registry parent class"},{"target":"primary metabolic process","type":"related","note":"in registry terms"},{"target":"organic substance metabolic process","type":"related","note":"in registry terms"},{"target":"glycolysis","type":"related","note":"as the central catabolic route"},{"target":"insulin","type":"related","note":"and glucagon"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.carbohydrate-metabolic-process","Wikidata: Q2734081 (https://www.wikidata.org/wiki/Q2734081)","GO: GO:0005975 carbohydrate metabolic process","KEGG: map00010 and related glycolysis and carbohydrate pathways"]},"properties":{"applicability":"not-applicable","items":["glycolysis yield: 2 ATP per glucose - net","key hormones: insulin, glucagon list","main storage form: glycogen note - in animals"]},"recognition":{"applicability":"optional","items":["Synthesis and breakdown of carbohydrates","Monosaccharide, oligosaccharide and polysaccharide metabolism, carbohydrate biosynthesis, Lewis x epitope biosynthesis","Lipid and protein metabolism handle other classes; dietary carbohydrate is a nutrition topic","Not a visible object; biochemical pathways."]},"capabilities":{"applicability":"required","items":["explain pathways","relay regulation and disorders","describe glycan biosynthesis","distinguish related metabolism"]},"hazards":{"applicability":"required","items":["Confusing metabolism with dietary carbohydrate topics","Agents giving personal medical or dietary advice","Oversimplifying regulation"]},"interfaces":{"applicability":"required","items":["Gene Ontology and KEGG pathway definitions","Newborn screening for inherited carbohydrate disorders such as galactosaemia"]},"context":{"applicability":"required","items":["Not applicable; a metabolic process.","monosaccharide metabolism including glycolysis, gluconeogenesis and the pentose phosphate pathway","oligosaccharide metabolism","polysaccharide metabolism including glycogen and starch","carbohydrate biosynthesis","glycan and epitope biosynthesis such as the Lewis x epitope","cellular carbohydrate metabolism in specific compartments"]}},"sources":[{"title":"Wikidata item Q2734081: carbohydrate metabolic process","url":"https://www.wikidata.org/wiki/Q2734081","note":"identity and sense of the item"},{"title":"Wikipedia: Carbohydrate metabolism","url":"https://en.wikipedia.org/wiki/Carbohydrate_metabolism","note":"general description of the item"}],"openQuestions":["Should glycolysis and glycogen metabolism be separate primary entries?","How should biochemistry references be linked?","The registry entry has merged aliases naming Gene Ontology subterms; should they be split off?"],"resources":{"spec":"/models/things/publications/thing-q2734081/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q2734081/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-13T06:18:08Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"not-applicable","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-06T19:51:58+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass","interaction.properties":"Plane ACT: no invented physical properties."},"score":1.0}}