{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.lipid-metabolism","code":"thing-q2792936","url":"https://ver.cy/models/thing/q2792936/","name":"lipid metabolism","alternateNames":["testosterone biosynthetic process","helvolic acid biosynthetic process","androst-4-ene-3,17-dione biosynthetic process","steroid hormone biosynthetic process","emericellamide biosynthetic process","(17Z)-protosta-17(20),24-dien-3beta-ol biosynthetic process","isoprenoid biosynthetic process","phospholipid biosynthetic process","membrane lipid biosynthetic process","glycerolipid biosynthetic process","neutral lipid biosynthetic process","lipid biosynthetic process"],"kind":"thing","status":"published","version":"0.2.0-wave.2","language":"en","classifiers":{"family":"Thing Registry","category":"Activities and processes","entryKind":"thing","plane":"ACT","domain":["ACT.PRC"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"The set of biochemical processes by which organisms synthesise, transport, store and break down lipids, including fatty acid synthesis and oxidation, triglyceride and phospholipid metabolism, cholesterol and steroid biosynthesis leading to hormones such as testosterone and androstenedione, and specialised pathways in microbes producing compounds such as helvolic acid; lipid metabolism supplies energy and membrane components, and its disorders underlie conditions such as dyslipidaemia and fatty liver disease.","purpose":"Let an agent explain lipid metabolism and its pathways, describe regulation and its role in health and disease in general terms, relate lipid metabolism to diet and medicines from health sources, and support learning in biochemistry.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Energy storage","Membrane components","Steroid hormone synthesis","Hormonal regulation"],"structure":{"bundles":[{"id":"understand","name":"Understand","description":"What lipid metabolism is.","layers":[{"id":"pathways","name":"Pathways","description":"Pathways.","findings":[{"id":"pathways-finding","name":"Pathways","description":"Pathways.","questions":[{"text":"How are fatty acids synthesised and oxidised, and how are triglycerides, phospholipids and cholesterol made and broken down?","kind":"definition"},{"text":"Which entry fits a specific pathway?","kind":"action"}]}]},{"id":"steroids","name":"Steroids","description":"Steroid biosynthesis.","findings":[{"id":"steroids-finding","name":"Steroids","description":"Steroids.","questions":[{"text":"How are steroid hormones such as testosterone synthesised from cholesterol?","kind":"definition"},{"text":"Which entry fits a specific hormone?","kind":"action"}]}]}]},{"id":"regulate","name":"Regulate","description":"Regulation and transport.","layers":[{"id":"regulation","name":"Regulation","description":"Regulation.","findings":[{"id":"regulation-finding","name":"Regulation","description":"Regulation.","questions":[{"text":"How do insulin, glucagon and other signals regulate lipid metabolism in fed and fasting states?","kind":"definition"},{"text":"Which entry fits metabolic regulation?","kind":"action"}]}]},{"id":"transport","name":"Transport","description":"Lipoproteins.","findings":[{"id":"transport-finding","name":"Transport","description":"Transport.","questions":[{"text":"How are lipids transported in lipoproteins, and what do LDL and HDL mean?","kind":"definition"},{"text":"Which entry fits lipoproteins?","kind":"action"}]}]}]},{"id":"health","name":"Health","description":"Health and disease.","layers":[{"id":"disorders","name":"Disorders","description":"Disorders.","findings":[{"id":"disorders-finding","name":"Disorders","description":"Disorders.","questions":[{"text":"What disorders of lipid metabolism exist, and how are they managed, according to guidelines?","kind":"provenance"},{"text":"Is the user asking about their own results, which need a clinician?","kind":"boundary"}]}]},{"id":"diet","name":"Diet","description":"Diet and medicines.","findings":[{"id":"diet-finding","name":"Diet","description":"Diet.","questions":[{"text":"What do health bodies say about dietary fats, cholesterol and lipid-lowering medicines?","kind":"provenance"},{"text":"Which entry fits nutrition?","kind":"action"}]}]}]},{"id":"learn","name":"Learn","description":"History and teaching.","layers":[{"id":"history","name":"History","description":"History.","findings":[{"id":"history-finding","name":"History","description":"History.","questions":[{"text":"How were lipid pathways discovered?","kind":"provenance"},{"text":"Which references are standard?","kind":"provenance"}]}]},{"id":"teach","name":"Teach","description":"Teaching.","findings":[{"id":"teach-finding","name":"Teach","description":"Teaching.","questions":[{"text":"How can lipid metabolism be taught in biochemistry courses?","kind":"action"},{"text":"Which misconceptions arise?","kind":"provenance"}]}]}]}]},"agentConduct":{"may":["Explain lipid metabolism pathways in general terms.","Point people to clinicians for cholesterol and metabolic concerns."],"mustNot":["Give a person dietary or drug advice for their lipid levels.","Oversimplify links between diet and cholesterol.","Promote unproven supplements.","Confuse metabolic pathways in teaching."],"requiresHuman":["Any treatment decision about lipid disorders."]},"ethics":{"considerations":["Diet advice can harm people with metabolic conditions.","Weight and diet carry stigma."],"affectedParties":["Patients","Students","Clinicians"]},"owners":{"steward":"Nobody owns the process; it is held in common.","roles":[],"masterSystems":[]},"relations":[{"target":"Q1057","type":"parent","note":"registry parent class"},{"target":"Q13878858","type":"parent","note":"registry parent class"},{"target":"Q19708902","type":"parent","note":"registry parent class"},{"target":"Q21149516","type":"parent","note":"registry parent class"},{"target":"metabolism","type":"related","note":"category"},{"target":"primary metabolic process","type":"related","note":"category"},{"target":"esterase","type":"related","note":"lipases in lipid breakdown"},{"target":"liver cancer","type":"related","note":"liver disease links"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.lipid-metabolism","Wikidata: Q2792936 (https://www.wikidata.org/wiki/Q2792936)"]},"properties":{"applicability":"not-applicable","items":[]},"recognition":{"applicability":"optional","items":["Synthesis and breakdown of lipids","Fatty acids, triglycerides, cholesterol, steroids","Carbohydrate and protein metabolism are parallel systems","Not visible; biochemical pathways."]},"capabilities":{"applicability":"required","items":["explain pathways","describe regulation and disease generally","relate to diet and medicines","support learning"]},"hazards":{"applicability":"required","items":["Agents giving personal medical or dietary advice","Oversimplifying cholesterol and diet links","Confusing pathways"]},"interfaces":{"applicability":"required","items":["Biochemical nomenclature and pathway databases","Clinical guidelines on lipid disorders","Dietary guidelines"]},"context":{"applicability":"required","items":["Metabolism of fats and related molecules.","fatty acid synthesis and oxidation","triglyceride and phospholipid metabolism","cholesterol biosynthesis","steroid hormone biosynthesis","specialised microbial lipid pathways"]}},"sources":[{"title":"Wikidata item Q2792936: lipid metabolism","url":"https://www.wikidata.org/wiki/Q2792936","note":"identity and sense of the item"},{"title":"Wikipedia: Lipid metabolism","url":"https://en.wikipedia.org/wiki/Lipid_metabolism","note":"general description of the item"}],"openQuestions":["Should each pathway be a separate entry?","How should pathway databases be linked?","How should clinical guidelines be linked?"],"resources":{"spec":"/models/things/publications/thing-q2792936/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q2792936/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-12T02:41:47Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"not-applicable","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-06T19:51:58+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass","interaction.properties":"Plane ACT: no invented physical properties."},"score":1.0}}