{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.linolelaidic-acid","code":"thing-q2823277","url":"https://ver.cy/models/thing/q2823277/","name":"linolelaidic acid","alternateNames":[],"kind":"thing","status":"published","version":"0.1.0-research.1","language":"en","classifiers":{"family":"Thing Registry","category":"Physical world and living systems","entryKind":"thing","plane":"PHY","domain":["PHY.MAT"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"Linolelaidic acid is the straight-chain, 18-carbon polyunsaturated fatty acid (9E,12E)-octadeca-9,12-dienoic acid, the trans,trans geometric isomer of linoleic acid.","purpose":"Enable an agent to identify linolelaidic acid, assess the identity and condition of a sample, and determine its suitability for a specified analytical or research use.","scope":{"in":["The 18-carbon free acid with double bonds at positions 9 and 12, both in the E configuration","Chemical identifiers and distinctions from related fatty-acid isomers","Sample assay, stereochemical purity, contaminants and grade","Physical properties with measurement conditions and preparation state","Oxidation, storage history and evidence of continued suitability","Substance-specific safety evidence and applicable use restrictions"],"out":["Linoleic acid and other geometric or positional isomers as independent substances","Linolelaidate salts, esters and esterified lipid residues as independent chemical entities","Foods, oils and commercial formulations containing linolelaidic acid","Manufacturing processes and hydrogenation equipment","Population-level health effects of trans fats as a class","Complete experimental protocols and laboratory facility management"],"boundaries":[]},"distinguishingFeatures":["Require the explicit structure (9E,12E)-octadeca-9,12-dienoic acid; both specified double bonds must be trans. [ChEBI](https://www.ebi.ac.uk/chebi/CHEBI:75108)","Distinguish the 9E,12E configuration from the 9Z,12Z and mixed E/Z alternatives; a generic C18:2 label does not settle identity.","Require double bonds at positions 9 and 12, separated by a methylene group, rather than a conjugated or differently positioned diene.","Require the free carboxylic acid rather than a salt, methyl ester, ethyl ester or glycerol-bound residue.","Use CAS 506-21-8 and a stereochemically explicit structure together when reconciling names such as linoelaidic acid. [ChEBI](https://www.ebi.ac.uk/chebi/CHEBI:75108)"],"structure":{"bundles":[{"id":"molecular-identity","name":"Molecular identity","description":"Establish what counts as linolelaidic acid and where neighbouring chemical identities begin.","layers":[{"id":"chain-and-stereochemistry","name":"Chain and stereochemistry","description":"Resolve the structural information required for an exact identity match.","findings":[{"id":"explicit-trans-diene","name":"Explicit trans diene","description":"Require evidence for an 18-carbon acid with 9E and 12E double bonds rather than accepting an unspecified C18:2 assignment.","questions":[{"text":"Does the identity record explicitly establish both double-bond positions and both E configurations?","id":"explicit-trans-diene-q01","kind":"definition"},{"text":"What evidence excludes the cis,cis, mixed-geometry and positional C18:2 alternatives?","id":"explicit-trans-diene-q02","kind":"boundary"}]}]},{"id":"names-and-chemical-forms","name":"Names and chemical forms","description":"Connect spelling variants to the free acid while keeping derivatives distinct.","findings":[{"id":"free-acid-record-match","name":"Free-acid record match","description":"Reconcile identifiers against the explicit structure and record salts, esters and lipid-bound residues as related entities.","questions":[{"text":"Which authoritative record connects the supplied name and identifiers to the 9E,12E free acid?","id":"free-acid-record-match-q01","kind":"provenance"},{"text":"Does the material contain the free acid, a carboxylate salt or an esterified linolelaidoyl group?","id":"free-acid-record-match-q02","kind":"boundary"}]}]}]},{"id":"sample-composition-and-analysis","name":"Sample composition and analysis","description":"Determine how much target acid is present and how securely its identity and purity are measured.","layers":[{"id":"assay-and-impurities","name":"Assay and impurities","description":"Separate target content, isomer purity and non-fatty-acid components.","findings":[{"id":"purity-basis","name":"Purity basis","description":"Record total target assay separately from chromatographic area purity and the fraction of 9E,12E within the C18:2 pool.","questions":[{"text":"Is the reported purity a mass fraction, mole fraction or chromatographic area fraction, and does it include solvent?","id":"purity-basis-q01","kind":"measurement"},{"text":"Which other C18:2 isomers, residual solvents, water and oxidation products were quantified or left unresolved?","id":"purity-basis-q02","kind":"measurement"}]}]},{"id":"isomer-resolving-evidence","name":"Isomer-resolving evidence","description":"Assess whether the analytical method supports the specificity claimed.","findings":[{"id":"analytical-specificity","name":"Analytical specificity","description":"Require demonstrated discrimination of relevant isomers and preserve the connection between the original sample and any analytical derivative.","questions":[{"text":"What reference materials and separation or spectroscopic evidence demonstrate discrimination of 9E,12E from likely interferents?","id":"analytical-specificity-q01","kind":"measurement"},{"text":"If the assay measures fatty-acid methyl esters, what validates conversion, recovery and preservation of the original double-bond geometry?","id":"analytical-specificity-q02","kind":"provenance"}]}]}]},{"id":"physical-state-and-preparation","name":"Physical state and preparation","description":"Describe the condition-dependent properties needed to handle and prepare the acid.","layers":[{"id":"neat-material-properties","name":"Neat-material properties","description":"Keep intrinsic-property measurements attached to their actual experimental conditions.","findings":[{"id":"conditional-thermal-behaviour","name":"Conditional thermal behaviour","description":"Record measured phase and thermal transitions without assigning unverified numerical constants.","questions":[{"text":"What phase and melting interval are measured for a sample of documented stereochemical purity at the stated temperature history?","id":"conditional-thermal-behaviour-q01","kind":"measurement"},{"text":"Is a reported boiling value experimentally measured at a specified pressure, estimated, or actually a decomposition observation?","id":"conditional-thermal-behaviour-q02","kind":"provenance"}]}]},{"id":"solutions-and-speciation","name":"Solutions and speciation","description":"Connect solvent, pH and preparation conditions to the material actually available in solution.","findings":[{"id":"available-dissolved-acid","name":"Available dissolved acid","description":"Supplier data report limited aqueous solubility and buffer-dependent values; retain those conditions rather than treating solubility as a universal constant. [Cayman product information](https://cdn.caymanchem.com/cdn/insert/90160.pdf)","questions":[{"text":"At the intended solvent composition, pH and temperature, what dissolved concentration is measured rather than merely added?","id":"available-dissolved-acid-q01","kind":"measurement"},{"text":"Does the preparation contain predominantly neutral acid, carboxylate or dispersed material, and how does that affect the intended use?","id":"available-dissolved-acid-q02","kind":"action"}]}]}]},{"id":"stability-and-storage","name":"Stability and storage","description":"Track whether the sample retains its intended composition through storage and preparation.","layers":[{"id":"oxidation-and-transformation","name":"Oxidation and transformation","description":"Assess chemical change instead of treating an unchanged label as proof of unchanged material.","findings":[{"id":"current-composition-integrity","name":"Current composition integrity","description":"Use oxidation and identity measurements to decide whether the sample remains representative of the specified acid.","questions":[{"text":"Which measurements detect primary and secondary oxidation products at limits relevant to the proposed application?","id":"current-composition-integrity-q01","kind":"measurement"},{"text":"After heating, illumination or processing, is there evidence of oxidation, isomerization or other compositional change?","id":"current-composition-integrity-q02","kind":"measurement"}]}]},{"id":"storage-history-and-retest","name":"Storage history and retest","description":"Apply storage guidance to the preparation and lot for which it is supported.","findings":[{"id":"preparation-specific-lifetime","name":"Preparation-specific lifetime","description":"Keep supplier shelf-life claims tied to the supplied formulation; opened stocks and aqueous preparations require their own supported limits.","questions":[{"text":"What temperature, light exposure, headspace conditions and opening history are documented for this sample?","id":"preparation-specific-lifetime-q01","kind":"provenance"},{"text":"Which storage excursion, elapsed preparation time or analytical result triggers retesting or rejection?","id":"preparation-specific-lifetime-q02","kind":"action"}]}]}]},{"id":"use-fitness-and-safety","name":"Use fitness and safety","description":"Connect documented material quality and safety evidence to a proposed use.","layers":[{"id":"application-acceptance","name":"Application acceptance","description":"Define which sample qualities matter for the specific analytical or research task.","findings":[{"id":"grade-and-task-match","name":"Grade and task match","description":"Distinguish a research reagent from a certified reference material and require application-specific limits for isomers, solvent and degradation.","questions":[{"text":"Does the intended use require identity confirmation, quantitative calibration or biological exposure, and what quality criteria follow?","id":"grade-and-task-match-q01","kind":"action"},{"text":"What lot certificate, uncertainty statement and traceability evidence support any claim that this material is a quantitative reference standard?","id":"grade-and-task-match-q02","kind":"provenance"}]}]},{"id":"hazards-and-jurisdiction","name":"Hazards and jurisdiction","description":"Resolve safety and regulatory evidence for the acid and its actual preparation.","findings":[{"id":"documented-use-constraints","name":"Documented use constraints","description":"Record current classification and restrictions with source and jurisdiction, separating evidence for neat acid from solvent-related preparation hazards.","questions":[{"text":"Which dated SDS and jurisdiction-specific records establish the classification, EC identity and any applicable occupational exposure limits?","id":"documented-use-constraints-q01","kind":"provenance"},{"text":"What handling, storage and disposal conditions follow from the actual preparation and intended operation?","id":"documented-use-constraints-q02","kind":"action"},{"text":"Which restrictions apply specifically to linolelaidic acid, and which apply to a containing product or a broader trans-fat category?","id":"documented-use-constraints-q03","kind":"boundary"}]}]}]},{"id":"evidence-and-external-alignment","name":"Evidence and external alignment","description":"What the world already says about this thing, gathered so the model can be checked against it.","layers":[{"id":"reported-evidence","name":"Reported evidence","description":"Findings from the breadth pass, kept separate from the structural claims.","findings":[{"id":"evidence-confidence-notes","name":"Check these first","description":"Recalled without web access and unsourced; every item is a lead to verify.","questions":[{"text":"Which of these check these first hold for the sense of linolelaidic acid this model covers, and on what evidence?","id":"evidence-confidence-notes-q01","kind":"provenance"}]},{"id":"evidence-identifiers","name":"Identifiers and schemes","description":"Recalled without web access and unsourced; every item is a lead to verify.","questions":[{"text":"Which of these identifiers and schemes hold for the sense of linolelaidic acid this model covers, and on what evidence?","id":"evidence-identifiers-q01","kind":"provenance"}]},{"id":"evidence-real-world-use","name":"Real-world use","description":"Recalled without web access and unsourced; every item is a lead to verify.","questions":[{"text":"Which of these real-world use hold for the sense of linolelaidic acid this model covers, and on what evidence?","id":"evidence-real-world-use-q01","kind":"provenance"}]},{"id":"evidence-measurements","name":"Typical measurements","description":"Recalled without web access and unsourced; every item is a lead to verify.","questions":[{"text":"Which of these typical measurements hold for the sense of linolelaidic acid this model covers, and on what evidence?","id":"evidence-measurements-q01","kind":"provenance"}]},{"id":"evidence-failure-modes-and-hazards","name":"Failure modes and hazards","description":"Recalled without web access and unsourced; every item is a lead to verify.","questions":[{"text":"Which of these failure modes and hazards hold for the sense of linolelaidic acid this model covers, and on what evidence?","id":"evidence-failure-modes-and-hazards-q01","kind":"provenance"}]},{"id":"evidence-neighbours","name":"Neighbouring kinds and how to tell them apart","description":"Recalled without web access and unsourced; every item is a lead to verify.","questions":[{"text":"Which of these neighbouring kinds and how to tell them apart hold for the sense of linolelaidic acid this model covers, and on what evidence?","id":"evidence-neighbours-q01","kind":"provenance"}]}]}]}]},"agentConduct":{"may":["Identify linolelaidic acid as the trans,trans isomer of linoleic acid, citing sources.","Report its measured content in a food or sample with the method used."],"mustNot":["Present it as a healthy fat or interchangeable with linoleic acid.","Understate trans fat content on food labels or in reports.","Recommend diets to a person based on it without professional advice.","Label a sample without analysis of isomer form."],"requiresHuman":["Reformulating foods that contain trans fats.","Publishing nutrition claims about it."]},"ethics":{"considerations":["Industrial trans fats raise heart disease risk, and honest labelling protects consumers.","Low-income consumers often eat more processed foods with trans fats."],"affectedParties":["Consumers","Food producers","Public health bodies"]},"owners":{"steward":"The laboratory or producer that holds the material.","roles":[],"masterSystems":[]},"relations":[{"target":"Q27163939","type":"parent","note":"registry parent class"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.linolelaidic-acid","Wikidata: Q2823277 (https://www.wikidata.org/wiki/Q2823277)"]},"properties":{"applicability":"required","items":["Molecular composition: C18H32O2; neutral free acid","Double-bond identity: 18:2(9E,12E)","Identifier mapping: CAS 506-21-8; PubChem CID 5282457; ChEBI CHEBI:75108; EC number unresolved","Free-acid assay: Mass % or mol %, with method, uncertainty and reporting basis","Geometric and positional isomer purity: % 9E,12E among resolved C18:2 isomers; individual impurity fractions","Preparation and phase: Neat solid, neat liquid or solution; temperature in °C; solvent and concentration where applicable","Thermal properties: Melting interval in °C; boiling temperature in °C at stated pressure, or observed decomposition","Solubility and dissolved concentration: mg/mL or mol/L with solvent, temperature, pH and equilibration conditions","Oxidative condition: Untested, within specified limits or degraded; linked oxidation measurements","Safety and regulatory evidence: Dated SDS; jurisdiction; classification; exposure-limit source or explicit unresolved status"]},"recognition":{"applicability":"required","items":["A fatty acid that cannot be told from its isomers by sight.","Identity is settled by gas chromatography or spectroscopy."]},"capabilities":{"applicability":"required","items":["Reconcile a named material with the stereochemically explicit registry identity.","Assess whether analytical evidence resolves linolelaidic acid from neighbouring C18:2 isomers.","Compare lots against assay, isomer-purity and oxidation acceptance criteria.","Select a documented preparation condition for a target dissolved concentration.","Flag samples for retesting after storage excursions or suspected degradation.","Determine whether grade, safety documentation and use restrictions support a proposed research application."]},"hazards":{"applicability":"required","items":["Misreporting of trans fat content in foods.","Confusion with linoleic acid in data."]},"interfaces":{"applicability":"required","items":["Commission Regulation (EU) 2019/649 on trans fat other than trans fat naturally occurring in fat of animal origin, European Union."]},"context":{"applicability":"required","items":["Linolelaidic acid is encountered in lipid chemistry and analytical studies that distinguish trans fatty acids from their cis counterparts.","It can serve as a reference material for identifying the trans,trans isomer in fatty acid mixtures.","Research uses include examining how double-bond geometry affects lipid properties and biological interactions."]}},"sources":[{"title":"Wikidata item Q2823277: linolelaidic acid","url":"https://www.wikidata.org/wiki/Q2823277","note":"identity and sense of the item"},{"title":"Wikipedia: Linolelaidic acid","url":"https://en.wikipedia.org/wiki/Linolelaidic_acid","note":"general description of the item"}],"openQuestions":["Which primary measurements establish the melting interval and any boiling or decomposition behaviour of highly pure 9E,12E free acid?","What EC identifier, current jurisdiction-specific GHS classifications and substance-specific exposure limits can be verified, including explicit evidence where no limit is established?","Which validated analytical methods resolve the likely C18:2 isomers and preserve geometry during extraction and derivatization?","What oxidation acceptance criteria and retest intervals are supported for neat acid, opened organic stocks and aqueous preparations?","Which documented grades and certified reference materials are available, and what purity, uncertainty and traceability claims apply to each?"],"resources":{"spec":"/models/things/publications/thing-q2823277/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q2823277/spec.json"],"providers":["Codex"],"researchStatus":"unreviewed","generatedAt":"2026-09-12T10:58:59Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"filled","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-07T10:10:29+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass"},"score":1.0}}