{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.ehrlichiosis","code":"thing-q2845432","url":"https://ver.cy/models/thing/q2845432/","name":"ehrlichiosis","alternateNames":["human granulocytic anaplasmosis","heartwater disease","bovine ehrlichiosis","human ehrlichiosis","sennetsu fever","human monocytic ehrlichiosis","Ehrlichiosis ewingii infection"],"kind":"thing","status":"published","version":"0.2.0-wave.4","language":"en","classifiers":{"family":"Thing Registry","category":"Activities and processes","entryKind":"thing","plane":"ACT","domain":["ACT.PRC"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"A human tick-borne bacterial disease caused by Ehrlichia species that infect white blood cells, including human monocytic ehrlichiosis caused by Ehrlichia chaffeensis, mainly in the south-central and south-eastern United States; related infections the registry aliases name include human granulocytic anaplasmosis, caused by Anaplasma phagocytophilum, and sennetsu fever, caused by Neorickettsia sennetsu, which belong to related genera. Symptoms include fever, headache, muscle aches and low blood counts, and illness can be severe, so people with fever after tick exposure should seek prompt medical care, as doxycycline treatment is most effective early.","purpose":"Let an agent explain human ehrlichiosis in general terms, relay causes, vectors, geography, symptoms, treatment approaches and prevention from CDC and infectious disease sources, route febrile illness after tick bites to prompt care, describe human forms and distinguish related infections and veterinary diseases from this human disease sense, and distinguish ehrlichiosis from Lyme disease, Rocky Mountain spotted fever, babesiosis and viral illnesses, without diagnosing individuals.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Human ehrlichiosis is tick-borne.","The causative bacteria infect white blood cells.","This sense covers disease in humans.","Early treatment matters."],"structure":{"bundles":[{"id":"understand","name":"Understand","description":"What ehrlichiosis is.","layers":[{"id":"definition","name":"Definition","description":"Definition.","findings":[{"id":"definition-finding","name":"Definition","description":"Definition.","questions":[{"text":"Does someone have fever, headache and aches after a tick bite or outdoor exposure, in which case seek prompt medical care?","kind":"boundary"},{"text":"What is ehrlichiosis, and how does it differ from Lyme disease, Rocky Mountain spotted fever, babesiosis and viral illness?","kind":"definition"}]}]},{"id":"forms","name":"Forms","description":"Named forms.","findings":[{"id":"forms-finding","name":"Forms","description":"Forms.","questions":[{"text":"What are human monocytic ehrlichiosis, bovine ehrlichiosis and heartwater, and what are anaplasmosis and sennetsu fever?","kind":"definition"},{"text":"Which entry fits the specific form?","kind":"action"}]}]}]},{"id":"biology","name":"Biology","description":"Biology.","layers":[{"id":"bacteria","name":"Bacteria","description":"Ehrlichia.","findings":[{"id":"bacteria-finding","name":"Bacteria","description":"Bacteria.","questions":[{"text":"How do Ehrlichia bacteria infect white blood cells?","kind":"provenance"},{"text":"Which references are standard?","kind":"provenance"}]}]},{"id":"ticks","name":"Ticks","description":"Vectors.","findings":[{"id":"ticks-finding","name":"Ticks","description":"Ticks.","questions":[{"text":"Which ticks transmit ehrlichiosis, and where are they found?","kind":"provenance"},{"text":"Which sources are cited?","kind":"provenance"}]}]}]},{"id":"care","name":"Care","description":"Treatment and prevention.","layers":[{"id":"treatment","name":"Treatment","description":"Treatment.","findings":[{"id":"treatment-finding","name":"Treatment","description":"Treatment.","questions":[{"text":"Why do guidelines recommend doxycycline early, including for children?","kind":"provenance"},{"text":"Which entry fits doxycycline?","kind":"action"}]}]},{"id":"prevention","name":"Prevention","description":"Tick bite prevention.","findings":[{"id":"prevention-finding","name":"Prevention","description":"Prevention.","questions":[{"text":"How can people prevent tick bites and remove ticks safely?","kind":"provenance"},{"text":"Which entry fits tick bite prevention?","kind":"action"}]}]}]},{"id":"context","name":"Context","description":"Animals.","layers":[{"id":"dogs","name":"Dogs","description":"Canine ehrlichiosis.","findings":[{"id":"dogs-finding","name":"Dogs","description":"Dogs.","questions":[{"text":"How does ehrlichiosis affect dogs, and when should owners see a vet?","kind":"provenance"},{"text":"Which entry fits canine monocytic ehrlichiosis?","kind":"action"}]}]},{"id":"heartwater","name":"Heartwater","description":"Heartwater.","findings":[{"id":"heartwater-finding","name":"Heartwater","description":"Heartwater.","questions":[{"text":"Why is heartwater a major livestock disease in Africa?","kind":"provenance"},{"text":"Is the information current?","kind":"boundary"}]}]}]}]},"agentConduct":{"may":["Explain human ehrlichiosis, its tick vectors and where it occurs in general terms with sources.","Share recognised advice on preventing tick bites and removing ticks promptly."],"mustNot":["Diagnose ehrlichiosis or advise on antibiotic treatment for a specific person.","Tell someone with fever after a tick bite to wait instead of seeking care.","Recommend unapproved pesticides on people, pets or land."],"requiresHuman":["Any clinical decision about testing or treatment."]},"ethics":{"considerations":["Delayed treatment can make the disease severe or fatal, so prompt referral matters."],"affectedParties":["People bitten by ticks may be affected.","Outdoor workers may be affected."]},"owners":{"steward":"Treating clinicians answer for care; public health agencies track reportable cases.","roles":[],"masterSystems":[]},"relations":[{"target":"Q135677168","type":"parent","note":"registry parent class"},{"target":"Q18553247","type":"parent","note":"registry parent class"},{"target":"primary bacterial infectious disease","type":"related","note":"in registry terms"},{"target":"Ehrlichia chaffeensis","type":"related","note":"in human monocytic form"},{"target":"Amblyomma americanum","type":"related"},{"target":"Lyme disease","type":"related"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.ehrlichiosis","Wikidata: Q2845432 (https://www.wikidata.org/wiki/Q2845432)"]},"properties":{"applicability":"not-applicable","items":["main US vector: lone star tick Amblyomma americanum note","first human case recognised in US: 1986 year","first-line treatment: doxycycline note - all ages per CDC"]},"recognition":{"applicability":"optional","items":["Human ehrlichiosis comprises tick-borne Ehrlichia infections in people.","Human monocytic ehrlichiosis is included, while human granulocytic anaplasmosis and sennetsu fever are distinct infections and heartwater and bovine ehrlichiosis are veterinary diseases outside this sense.","Lyme disease is caused by Borrelia, Rocky Mountain spotted fever by Rickettsia, babesiosis by protozoa, and viral illnesses lack a bacterial cause.","Usually no specific visible sign; sometimes a rash, especially in children."]},"capabilities":{"applicability":"required","items":["explain causes and vectors","relay symptoms and treatment approaches","describe named forms and related infections","relay tick bite prevention"]},"hazards":{"applicability":"required","items":["Delayed treatment","Diagnosing individuals","Treating related genera as Ehrlichia"]},"interfaces":{"applicability":"required","items":["CDC tick-borne disease guidance","Notifiable disease reporting","WOAH listing of heartwater"]},"context":{"applicability":"required","items":["Not applicable; a group of tick-borne diseases.","human monocytic ehrlichiosis","Ehrlichia ewingii infection","canine ehrlichiosis","heartwater in ruminants","related anaplasmosis and neorickettsiosis"]}},"sources":[{"title":"Wikidata item Q2845432: ehrlichiosis","url":"https://www.wikidata.org/wiki/Q2845432","note":"identity and sense of the item"},{"title":"Wikipedia: Ehrlichiosis","url":"https://en.wikipedia.org/wiki/Ehrlichiosis","note":"general description of the item"}],"openQuestions":["The registry aliases human granulocytic anaplasmosis and sennetsu fever should be moved to their own entries","Should heartwater be a separate veterinary entry?","How should tick distribution data be kept current?"],"resources":{"spec":"/models/things/publications/thing-q2845432/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q2845432/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-13T23:45:34Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"not-applicable","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-07T10:10:29+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass","interaction.properties":"Plane ACT: no invented physical properties."},"score":1.0}}