{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.loose-connective-tissue","code":"thing-q3312266","url":"https://ver.cy/models/thing/q3312266/","name":"loose connective tissue","alternateNames":["capsule of thymus","stroma of ovarian medulla","mucoid tissue","pigmented connective tissue","reticular tissue","stroma of bone marrow","areolar connective tissue","synovial intima","synovial subintima","hypodermis","loose connective tissue of abdomen","trabecular tissue of sclera"],"kind":"thing","status":"published","version":"0.2.0-wave.4","language":"en","classifiers":{"family":"Thing Registry","category":"Physical world and living systems","entryKind":"thing","plane":"PHY","domain":["PHY.LIV"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"A category of connective tissue with abundant ground substance and loosely arranged fibres and cells, filling spaces, supporting organs, surrounding vessels and nerves and hosting immune cells, including areolar tissue, adipose tissue and reticular tissue; forms and locations the registry aliases name include reticular tissue, which forms the framework of lymphoid organs and bone marrow stroma, mucoid or mucous connective tissue as in the umbilical cord s Wharton jelly, pigmented connective tissue, and organ-specific loose tissue such as ovarian medulla stroma. It contrasts with dense connective tissue, which has tightly packed fibres and forms the thymus capsule.","purpose":"Let an agent explain loose connective tissue, relay types, cells, functions and locations from histology sources, describe the named forms, and distinguish loose from dense connective tissue, specialised connective tissues such as bone and blood, and epithelium.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Loosely arranged fibres","Abundant ground substance","Immune cells present","Fills spaces"],"structure":{"bundles":[{"id":"understand","name":"Understand","description":"What loose connective tissue is.","layers":[{"id":"definition","name":"Definition","description":"Definition.","findings":[{"id":"definition-finding","name":"Definition","description":"Definition.","questions":[{"text":"What is loose connective tissue, and how does it differ from dense connective tissue, bone and blood and epithelium?","kind":"definition"},{"text":"Is the question about histology, anatomy or a specific organ s stroma?","kind":"boundary"}]}]},{"id":"forms","name":"Forms","description":"Named forms.","findings":[{"id":"forms-finding","name":"Forms","description":"Forms.","questions":[{"text":"What are areolar, reticular, mucoid and pigmented connective tissue and organ-specific stroma?","kind":"definition"},{"text":"Which entry fits the specific form?","kind":"action"}]}]}]},{"id":"histology","name":"Histology","description":"Histology.","layers":[{"id":"cells","name":"Cells","description":"Cells.","findings":[{"id":"cells-finding","name":"Cells","description":"Cells.","questions":[{"text":"Which cells such as fibroblasts and immune cells populate loose tissue?","kind":"provenance"},{"text":"Which references are standard?","kind":"provenance"}]}]},{"id":"matrix","name":"Matrix","description":"Extracellular matrix.","findings":[{"id":"matrix-finding","name":"Matrix","description":"Matrix.","questions":[{"text":"What fibres and ground substance make up the matrix?","kind":"provenance"},{"text":"Which sources are cited?","kind":"provenance"}]}]}]},{"id":"functions","name":"Functions","description":"Functions.","layers":[{"id":"support","name":"Support","description":"Support and cushioning.","findings":[{"id":"support-finding","name":"Support","description":"Support.","questions":[{"text":"How does loose tissue support and cushion organs?","kind":"provenance"},{"text":"Which entry fits areolar tissue?","kind":"action"}]}]},{"id":"immune","name":"Immune","description":"Immune role.","findings":[{"id":"immune-finding","name":"Immune","description":"Immune.","questions":[{"text":"How does loose connective tissue host immune defence?","kind":"provenance"},{"text":"Is the information accurate?","kind":"boundary"}]}]}]},{"id":"context","name":"Context","description":"Specialised.","layers":[{"id":"reticular","name":"Reticular","description":"Reticular tissue.","findings":[{"id":"reticular-finding","name":"Reticular","description":"Reticular.","questions":[{"text":"How does reticular tissue frame lymphoid organs and bone marrow?","kind":"provenance"},{"text":"Which entry fits reticular fiber?","kind":"action"}]}]},{"id":"mucoid","name":"Mucoid","description":"Wharton jelly.","findings":[{"id":"mucoid-finding","name":"Mucoid","description":"Mucoid.","questions":[{"text":"What is mucoid connective tissue such as Wharton jelly?","kind":"provenance"},{"text":"Is the presentation neutral and attributed?","kind":"boundary"}]}]}]}]},"agentConduct":{"may":["Describe the types of loose connective tissue and where they are found.","Distinguish loose from dense connective tissue in teaching material."],"mustNot":["Treat the stroma of specific organs as separate tissue types without saying so.","Interpret a person's biopsy or histology report.","Present oversimplified histology as clinical fact."],"requiresHuman":["Using tissue descriptions to inform a diagnosis."]},"ethics":{"considerations":["Errors in teaching material carry into clinical practice.","Tissue samples come from people whose consent and privacy matter."],"affectedParties":["Students","Patients","Tissue donors"]},"owners":{"steward":"Nobody owns the concept; anatomists and pathologists maintain the science.","roles":[],"masterSystems":[]},"relations":[{"target":"Q112826975","type":"parent","note":"registry parent class"},{"target":"Q25615","type":"parent","note":"registry parent class"},{"target":"Q66511547","type":"parent","note":"registry parent class"},{"target":"connective tissue","type":"related","note":"in registry terms"},{"target":"areolar tissue","type":"related"},{"target":"dense connective tissue","type":"related"},{"target":"epithelium","type":"related"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.loose-connective-tissue","Wikidata: Q3312266 (https://www.wikidata.org/wiki/Q3312266)"]},"properties":{"applicability":"required","items":["main types: areolar, adipose, reticular list","ground substance: gel of glycosaminoglycans note","registry parents: connective tissue, irregular connective tissue note"]},"recognition":{"applicability":"required","items":["Loose connective tissue has loosely arranged fibres.","Examples include stroma of the ovarian medulla, mucoid tissue, pigmented connective tissue, reticular tissue and stroma of bone marrow.","Dense connective tissue has packed fibres and forms the thymus capsule, bone and blood are specialised connective tissues, and epithelium lines surfaces.","Under the microscope, sparse fibres and scattered cells in abundant ground substance."]},"capabilities":{"applicability":"required","items":["explain types and cells","relay functions","describe named forms","distinguish related tissues"]},"hazards":{"applicability":"required","items":["Confusing loose and dense connective tissue","Treating stroma of specific organs as separate tissue types","Oversimplified histology"]},"interfaces":{"applicability":"required","items":["Histology terminology standards"]},"context":{"applicability":"required","items":["Support, cushioning and immune defence between tissues.","areolar tissue","adipose tissue","reticular tissue","mucoid connective tissue"]}},"sources":[{"title":"Wikidata item Q3312266: loose connective tissue","url":"https://www.wikidata.org/wiki/Q3312266","note":"identity and sense of the item"},{"title":"Wikipedia: Loose connective tissue","url":"https://en.wikipedia.org/wiki/Loose_connective_tissue","note":"general description of the item"}],"openQuestions":["Should reticular and mucoid tissue be separate entries?","Should organ-specific stroma be treated as instances?","How should histology atlases be linked?"],"resources":{"spec":"/models/things/publications/thing-q3312266/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q3312266/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-14T02:02:46Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"filled","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-07T10:10:30+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass"},"score":1.0}}