{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.red-blood-cell","code":"thing-q37187","url":"https://ver.cy/models/thing/q37187/","name":"red blood cell","alternateNames":["acanthocyte","degmacyte","echinocyte","megaloblasts","microcyte","packed red blood cell","proerythroblast","nucleate erythrocyte","CD34-negative, GlyA-negative proerythroblast","Kit-low proerythroblast","human erythrocyte","fetal derived definitive erythrocyte"],"kind":"thing","status":"published","version":"0.2.0-wave.4","language":"en","classifiers":{"family":"Thing Registry","category":"Physical world and living systems","entryKind":"thing","plane":"PHY","domain":["PHY.OBJ"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"The most common type of blood cell, also called an erythrocyte, a biconcave disc without a nucleus in mammals that carries oxygen from the lungs to tissues and carbon dioxide back, using the protein haemoglobin; the registry aliases name abnormal shapes and forms seen on blood films such as acanthocytes with spiky projections, echinocytes, degmacytes or bite cells, microcytes that are small, megaloblasts that are large immature precursors, and packed red blood cells, a transfusion product. Red cell abnormalities help diagnose anaemias and other diseases, and severe anaemia symptoms such as breathlessness, chest pain or fainting need urgent care.","purpose":"Let an agent explain red blood cells, relay structure, function, production and abnormal forms from haematology sources, describe the named forms, route severe anaemia symptoms, and distinguish red cells from white cells, platelets, plasma and haemoglobin as a molecule.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Biconcave disc","No nucleus in mammals","Haemoglobin-filled","Diagnostic shape changes"],"structure":{"bundles":[{"id":"understand","name":"Understand","description":"What a red blood cell is.","layers":[{"id":"definition","name":"Definition","description":"Definition.","findings":[{"id":"definition-finding","name":"Definition","description":"Definition.","questions":[{"text":"Is there severe breathlessness, chest pain, fainting or very pale skin suggesting severe anaemia or blood loss, in which case seek urgent medical care?","kind":"boundary"},{"text":"What is a red blood cell, and how does it differ from white cells, platelets, plasma and haemoglobin?","kind":"definition"}]}]},{"id":"forms","name":"Forms","description":"Named forms.","findings":[{"id":"forms-finding","name":"Forms","description":"Forms.","questions":[{"text":"What are acanthocytes, echinocytes, degmacytes, microcytes, megaloblasts and packed red cells?","kind":"definition"},{"text":"Which entry fits the specific form?","kind":"action"}]}]}]},{"id":"biology","name":"Biology","description":"Biology.","layers":[{"id":"structure","name":"Structure","description":"Structure and function.","findings":[{"id":"structure-finding","name":"Structure","description":"Structure.","questions":[{"text":"How does the biconcave shape aid oxygen transport?","kind":"provenance"},{"text":"Which references are standard?","kind":"provenance"}]}]},{"id":"production","name":"Production","description":"Erythropoiesis.","findings":[{"id":"production-finding","name":"Production","description":"Production.","questions":[{"text":"How are red cells made and regulated by erythropoietin?","kind":"provenance"},{"text":"Which sources are cited?","kind":"provenance"}]}]}]},{"id":"clinical","name":"Clinical","description":"Clinical use.","layers":[{"id":"films","name":"Blood films","description":"Blood films.","findings":[{"id":"films-finding","name":"Blood films","description":"Blood films.","questions":[{"text":"How do abnormal shapes point to specific diseases?","kind":"provenance"},{"text":"Which entry fits blood film?","kind":"action"}]}]},{"id":"anaemia","name":"Anaemia","description":"Anaemia.","findings":[{"id":"anaemia-finding","name":"Anaemia","description":"Anaemia.","questions":[{"text":"How are anaemias classified by red cell size?","kind":"provenance"},{"text":"Which entry fits anemia?","kind":"action"}]}]}]},{"id":"context","name":"Context","description":"Transfusion.","layers":[{"id":"transfusion","name":"Transfusion","description":"Blood products.","findings":[{"id":"transfusion-finding","name":"Transfusion","description":"Transfusion.","questions":[{"text":"How are packed red cells used in transfusion, and why is blood typing essential?","kind":"provenance"},{"text":"Is the information current?","kind":"boundary"}]}]},{"id":"doping","name":"Doping","description":"Blood doping.","findings":[{"id":"doping-finding","name":"Doping","description":"Doping.","questions":[{"text":"How do agencies describe blood doping and its risks, with positions attributed?","kind":"provenance"},{"text":"Is the presentation neutral and attributed?","kind":"boundary"}]}]}]}]},"agentConduct":{"may":["Explain the structure and function of red blood cells from medical sources.","Explain common blood test values in general terms with reference ranges and their limits.","Point people to blood donation services on request."],"mustNot":["Interpret a particular person's blood count as a diagnosis.","Advise iron, other supplements or transfusion for a particular person.","Share a person's blood results without consent.","Give advice that delays care for signs of severe anaemia or bleeding."],"requiresHuman":["Any decision on transfusion or treatment for a patient."]},"ethics":{"considerations":["Blood disorders such as sickle cell disease are linked to ancestry and can carry stigma.","Transfusion relies on donors' generosity and on strict safety."],"affectedParties":["Patients","Blood donors","Families with inherited blood disorders"]},"owners":{"steward":"Nobody owns the cell type; blood services answer for donated blood.","roles":[],"masterSystems":["Blood donor registries"]},"relations":[{"target":"Q211709","type":"parent","note":"registry parent class"},{"target":"blood cell","type":"related","note":"in registry terms"},{"target":"hemoglobin","type":"contains"},{"target":"white blood cell","type":"related"},{"target":"platelet","type":"related"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.red-blood-cell","Wikidata: Q37187 (https://www.wikidata.org/wiki/Q37187)"]},"properties":{"applicability":"required","items":["cell diameter: about 7-8 micrometres","lifespan: about 120 days","count: roughly 4-6 million per microlitre note - varies by sex and age"]},"recognition":{"applicability":"required","items":["Oxygen-carrying blood cell","Acanthocyte, degmacyte, echinocyte, megaloblast, microcyte, packed red blood cells","White cells fight infection; platelets aid clotting; plasma is the fluid; haemoglobin is the protein inside red cells","Red biconcave discs, appearing as pale-centred circles on stained blood films."]},"capabilities":{"applicability":"required","items":["explain structure and function","relay production","describe abnormal forms","route severe anaemia symptoms"]},"hazards":{"applicability":"required","items":["Severe anaemia","Transfusion reactions","Misreading blood films"]},"interfaces":{"applicability":"required","items":["Blood transfusion and blood product regulations","Laboratory reference ranges"]},"context":{"applicability":"required","items":["Carrying oxygen and carbon dioxide in blood.","normal erythrocytes","abnormal shapes such as acanthocytes and echinocytes","size variants such as microcytes and macrocytes","immature forms such as reticulocytes and megaloblasts"]}},"sources":[{"title":"Wikidata item Q37187: red blood cell","url":"https://www.wikidata.org/wiki/Q37187","note":"identity and sense of the item"},{"title":"Wikipedia: Red blood cell","url":"https://en.wikipedia.org/wiki/Red_blood_cell","note":"general description of the item"}],"openQuestions":["Should abnormal cell shapes be separate entries?","How should haematology atlases be linked?","Should packed red cells be moved to blood product entries?"],"resources":{"spec":"/models/things/publications/thing-q37187/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q37187/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-14T01:37:39Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"filled","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-06T19:51:59+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass"},"score":1.0}}