{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.tissue","code":"thing-q40397","url":"https://ver.cy/models/thing/q40397/","name":"tissue","alternateNames":[],"kind":"thing","status":"published","version":"0.2.0-wave.1","language":"en","classifiers":{"family":"Thing Registry","category":"Physical world and living systems","entryKind":"thing","plane":"PHY","domain":["PHY.LIV"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"In biology, a group of similar cells and their extracellular matrix working together to perform a function; animal tissues are classed as epithelial, connective, muscle and nervous, and plants have dermal, vascular and ground tissues.","purpose":"Let an agent explain biological tissues by type, structure and function, and point to clinical services for tissue samples and donation, without diagnosis.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Groups of similar cells","Specialised functions","Build organs","Studied by histology"],"structure":{"bundles":[{"id":"types","name":"Types","description":"Classification.","layers":[{"id":"kind","name":"Kind","description":"Tissue type.","findings":[{"id":"kind-finding","name":"Kind","description":"Tissue type.","questions":[{"text":"Which tissue type is this?","kind":"definition"},{"text":"Where is it found?","kind":"definition"}]}]},{"id":"function","name":"Function","description":"Role.","findings":[{"id":"function-finding","name":"Function","description":"Function.","questions":[{"text":"What does this tissue do?","kind":"definition"},{"text":"How is its structure suited to that?","kind":"definition"}]}]}]},{"id":"histology","name":"Histology","description":"Study.","layers":[{"id":"slides","name":"Slides","description":"Staining.","findings":[{"id":"slides-finding","name":"Slides","description":"Histology slides.","questions":[{"text":"How are tissue samples prepared and stained, in general terms?","kind":"definition"},{"text":"Which stains show which features?","kind":"definition"}]}]},{"id":"results","name":"Results","description":"Personal results.","findings":[{"id":"results-finding","name":"Results","description":"Results limit.","questions":[{"text":"Is the user asking the agent to interpret their biopsy?","kind":"boundary"},{"text":"How should they discuss it with a clinician?","kind":"action"}]}]}]},{"id":"donation","name":"Donation","description":"Tissue donation.","layers":[{"id":"donate","name":"Donate","description":"How to donate.","findings":[{"id":"donate-finding","name":"Donate","description":"Tissue donation.","questions":[{"text":"How can someone register as an organ or tissue donor here?","kind":"action"},{"text":"What does the law say about consent?","kind":"provenance"}]}]},{"id":"research","name":"Research","description":"Biobanks.","findings":[{"id":"research-finding","name":"Research","description":"Research use.","questions":[{"text":"How are donated tissues used in research, and with what consent?","kind":"provenance"},{"text":"Which rules apply?","kind":"provenance"}]}]}]},{"id":"senses","name":"Senses","description":"Disambiguation.","layers":[{"id":"paper","name":"Paper","description":"Tissue paper.","findings":[{"id":"paper-finding","name":"Paper","description":"Paper sense.","questions":[{"text":"Is facial tissue or tissue paper meant?","kind":"boundary"},{"text":"Which entry fits?","kind":"action"}]}]},{"id":"plants","name":"Plants","description":"Plant tissues.","findings":[{"id":"plants-finding","name":"Plants","description":"Plant tissues.","questions":[{"text":"Which plant tissues are involved?","kind":"definition"},{"text":"How do they differ from animal tissues?","kind":"definition"}]}]}]}]},"agentConduct":{"may":["Explain tissue types and functions from standard biology sources.","Help a laboratory track tissue samples it is authorized to manage."],"mustNot":["Use human tissue without the donor's consent and the required approvals.","Mislabel or mix up tissue samples.","Disclose donors' identities or results without consent.","Help trade human tissue in breach of the law."],"requiresHuman":["Releasing human tissue for research, transplant or disposal."]},"ethics":{"considerations":["Human tissue carries the dignity of the person it came from.","Consent and fair benefit matter, as past misuse of donors' tissue shows."],"affectedParties":["Tissue donors and families","Patients","Researchers"]},"owners":{"steward":"The holding institution for samples, under human tissue law and the donor's consent.","roles":[],"masterSystems":["Biobank and tissue licence registers"]},"relations":[{"target":"Q27062218","type":"parent","note":"registry parent class"},{"target":"Q289472","type":"parent","note":"registry parent class"},{"target":"Q28969293","type":"parent","note":"registry parent class"},{"target":"Q4936952","type":"parent","note":"registry parent class"},{"target":"multicellular structure","type":"related","note":"category"},{"target":"cell","type":"related","note":"units"},{"target":"organ","type":"related","note":"higher structure"},{"target":"histology and pathology","type":"related","note":"fields"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.tissue","Wikidata: Q40397 (https://www.wikidata.org/wiki/Q40397)"]},"properties":{"applicability":"required","items":["Mass density:  kilograms per cubic metre - Density is measured as sample mass divided by volume, with tissue type and hydration recorded.","Water mass fraction:  percent - Water content is measured using a validated moisture measurement method, with sample preparation recorded.","Elastic modulus:  pascals - Mechanical testing measures stiffness under specified loading, temperature and hydration conditions.","Sample thickness:  millimetres - Thickness is measured by imaging or suitable dimensional instruments, with compression and preservation conditions recorded."]},"recognition":{"applicability":"required","items":["Epithelial, connective, muscle, nervous","Histology slides","Paper tissues are a different sense","Seen under the microscope as organised cell layers; forms organs."]},"capabilities":{"applicability":"required","items":["classify tissue types","explain tissue structure and function","describe histology in general terms","find tissue donation information"]},"hazards":{"applicability":"required","items":["Agents interpreting personal biopsy results","Confusing senses"]},"interfaces":{"applicability":"required","items":["Human tissue law","EU tissues and cells directives"]},"context":{"applicability":"required","items":["Understanding how organs and bodies are built.","epithelial tissue","connective tissue","muscle tissue","nervous tissue","plant tissues"]}},"sources":[{"title":"Wikidata item Q40397: tissue","url":"https://www.wikidata.org/wiki/Q40397","note":"identity and sense of the item"},{"title":"Wikipedia: Tissue (biology)","url":"https://en.wikipedia.org/wiki/Tissue_%28biology%29","note":"general description of the item"}],"openQuestions":["Should tissue types be separate entries?","How should histology resources be linked?","How should the paper sense be split off?"],"resources":{"spec":"/models/things/publications/thing-q40397/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q40397/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-11T11:26:49Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"filled","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-07T10:10:30+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass"},"score":1.0}}