{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.flavone","code":"thing-q424525","url":"https://ver.cy/models/thing/q424525/","name":"flavone","alternateNames":[],"kind":"thing","status":"published","version":"0.2.0-wave.4","language":"en","classifiers":{"family":"Thing Registry","category":"Physical world and living systems","entryKind":"thing","plane":"PHY","domain":["PHY.MAT"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"A class of flavonoid compounds sharing the 2-phenylchromen-4-one skeleton, including apigenin, luteolin, chrysin and baicalein, with members occurring as plant secondary metabolites in sources such as parsley, celery, chamomile and citrus; flavones contribute to plant pigmentation and ultraviolet protection and are studied for antioxidant and biological activities, but health claims for supplements are often not established in human trials, and evidence about flavonoids generally does not establish effects or medicine interactions for every flavone.","purpose":"Let an agent explain flavone and flavones, relay structure, natural sources, plant roles and research status from chemistry, botany and nutrition sources with health claims attributed, and distinguish flavones from flavonols, flavanones, isoflavones and the broader flavonoid class.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["2-phenylchromen-4-one skeleton","Plant pigment role","UV absorption","Research interest"],"structure":{"bundles":[{"id":"understand","name":"Understand","description":"What flavone is.","layers":[{"id":"definition","name":"Definition","description":"Definition.","findings":[{"id":"definition-finding","name":"Definition","description":"Definition.","questions":[{"text":"What is flavone, and how does it differ from flavonols, flavanones, isoflavones and flavonoids generally?","kind":"definition"},{"text":"Is someone taking flavonoid supplements with medicines, in which case a pharmacist should check interactions?","kind":"boundary"}]}]},{"id":"examples","name":"Examples","description":"Examples.","findings":[{"id":"examples-finding","name":"Examples","description":"Examples.","questions":[{"text":"What are apigenin, luteolin, chrysin and baicalein?","kind":"definition"},{"text":"Which entry fits the specific compound?","kind":"action"}]}]}]},{"id":"chemistry","name":"Chemistry","description":"Chemistry.","layers":[{"id":"structure","name":"Structure","description":"Structure.","findings":[{"id":"structure-finding","name":"Structure","description":"Structure.","questions":[{"text":"What defines the flavone skeleton?","kind":"provenance"},{"text":"Which references are standard?","kind":"provenance"}]}]},{"id":"biosynthesis","name":"Biosynthesis","description":"Biosynthesis.","findings":[{"id":"biosynthesis-finding","name":"Biosynthesis","description":"Biosynthesis.","questions":[{"text":"How do plants make flavones via flavone synthase?","kind":"provenance"},{"text":"Which sources are cited?","kind":"provenance"}]}]}]},{"id":"biology","name":"Biology","description":"Plant roles.","layers":[{"id":"pigments","name":"Pigments","description":"Pigments and UV.","findings":[{"id":"pigments-finding","name":"Pigments","description":"Pigments.","questions":[{"text":"How do flavones colour flowers and protect against UV?","kind":"provenance"},{"text":"Which entry fits copigmentation?","kind":"action"}]}]},{"id":"foods","name":"Foods","description":"Food sources.","findings":[{"id":"foods-finding","name":"Foods","description":"Foods.","questions":[{"text":"Which foods contain flavones, according to composition databases?","kind":"provenance"},{"text":"Is the information accurate?","kind":"boundary"}]}]}]},{"id":"context","name":"Context","description":"Health research.","layers":[{"id":"research","name":"Research","description":"Research status.","findings":[{"id":"research-finding","name":"Research","description":"Research.","questions":[{"text":"What do laboratory and clinical studies report about flavones, and what limits apply, with findings attributed?","kind":"provenance"},{"text":"Is the presentation neutral and attributed?","kind":"boundary"}]}]},{"id":"claims","name":"Claims","description":"Supplement claims.","findings":[{"id":"claims-finding","name":"Claims","description":"Claims.","questions":[{"text":"How do regulators treat health claims for flavonoid supplements?","kind":"provenance"},{"text":"Is the information current?","kind":"boundary"}]}]}]}]},"agentConduct":{"may":["Describe flavones and related flavonoids from chemical and food science sources.","Handle individual flavone compounds following their safety data sheets in an authorized laboratory.","Explain the evidence on dietary flavonoids with its limits."],"mustNot":["Claim that flavone or flavonoid supplements cure or prevent disease.","Recommend supplement doses for a particular person.","Ignore known interactions between flavonoid supplements and medicines when asked about them.","Dispose of laboratory chemicals into drains against local rules."],"requiresHuman":["Human oversight is required for using flavones in products for human consumption or testing on people or animals."]},"ethics":{"considerations":["Health claims for plant compounds often outrun the evidence and exploit hope.","Laboratory chemicals must be handled so that workers and waterways are protected."],"affectedParties":["Consumers of supplements","Laboratory workers","Patients on medication"]},"owners":{"steward":"Nobody owns the chemical class; each holder answers for stocks of individual compounds they keep.","roles":[],"masterSystems":["Chemical substance registers record individual compounds."]},"relations":[{"target":"Q222174","type":"parent","note":"registry parent class"},{"target":"flavonoid","type":"related","note":"related"},{"target":"apigenin","type":"related"},{"target":"flavonol","type":"related"},{"target":"isoflavone","type":"related"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.flavone","Wikidata: Q424525 (https://www.wikidata.org/wiki/Q424525)"]},"properties":{"applicability":"required","items":["molecular formula: C15H10O2 formula","molar mass: about 222.2 g/mol","registry parent: 2-phenylchromane flavonoid note"]},"recognition":{"applicability":"required","items":["Flavones share a 2-phenylchromen-4-one skeleton.","Examples include apigenin, luteolin, chrysin and baicalein.","Flavonols have a 3-hydroxy group, flavanones lack the 2,3 double bond, isoflavones have the phenyl at position 3, and flavonoids are the broader class.","The parent compound is a colourless to pale yellow crystalline solid."]},"capabilities":{"applicability":"required","items":["explain structure","relay natural sources","relay plant roles","present health research with attribution"]},"hazards":{"applicability":"required","items":["Unsupported supplement claims","Drug interactions","Confusing flavone subclasses"]},"interfaces":{"applicability":"required","items":["Dietary supplement regulations","EU health claims regulation 1924/2006"]},"context":{"applicability":"required","items":["Plant pigments and research compounds.","apigenin-type flavones","luteolin-type flavones","methoxylated flavones","flavone glycosides"]}},"sources":[{"title":"Wikidata item Q424525: flavone","url":"https://www.wikidata.org/wiki/Q424525","note":"identity and sense of the item"},{"title":"Wikipedia: Flavones","url":"https://en.wikipedia.org/wiki/Flavones","note":"general description of the item"}],"openQuestions":["Should the parent compound and the flavone class be separate entries?","How should food composition databases be linked?","How should clinical evidence be summarised?"],"resources":{"spec":"/models/things/publications/thing-q424525/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q424525/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-14T01:11:04Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"filled","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-07T10:10:30+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass"},"score":1.0}}