{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.major-depressive-disorder","code":"thing-q42844","url":"https://ver.cy/models/thing/q42844/","name":"major depressive disorder","alternateNames":["Dorian Gray syndrome","depression in autism","treatment-resistant depression","double depression","melancholic depression","moderate recurrent major depression","mild recurrent major depression","melancholia","masked depression","anxiety/aggression-driven depression","depression of Alzheimer disease","recurrent major depression in complete remission"],"kind":"thing","status":"published","version":"0.2.0-wave.1","language":"en","classifiers":{"family":"Thing Registry","category":"Cross-cutting context","entryKind":"thing","plane":"XCT","domain":["XCT.STA"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"A common mental health condition characterised by persistent low mood or loss of interest or pleasure for at least two weeks, with changes in sleep, appetite, energy, concentration and self-worth, causing significant distress or impairment; it is treatable.","purpose":"Let an agent give neutral, non-diagnostic information about depression, point to professional care, and give crisis contacts first when someone may be at risk.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Lasts at least two weeks","Differs from ordinary sadness or grief in duration and impact","Treatable","Diagnosis needs a professional"],"structure":{"bundles":[{"id":"safety","name":"Safety","description":"Crisis first.","layers":[{"id":"risk","name":"Risk","description":"Immediate danger.","findings":[{"id":"risk-finding","name":"Risk","description":"Immediate risk.","questions":[{"text":"Is the person in immediate danger, and should emergency services or a crisis line be contacted now?","kind":"boundary"},{"text":"Which crisis line serves their country?","kind":"action"}]}]},{"id":"support","name":"Support","description":"Someone to talk to.","findings":[{"id":"support-finding","name":"Support","description":"Immediate support.","questions":[{"text":"Is there a trusted person who can be with them?","kind":"action"},{"text":"How can the agent stay supportive without advising on treatment?","kind":"boundary"}]}]}]},{"id":"care","name":"Care","description":"Professional help.","layers":[{"id":"assessment","name":"Assessment","description":"Seeing a professional.","findings":[{"id":"assessment-finding","name":"Assessment","description":"Assessment.","questions":[{"text":"How can someone get assessed by a doctor or mental health professional?","kind":"action"},{"text":"What can they expect?","kind":"definition"}]}]},{"id":"treatment","name":"Treatment","description":"Options.","findings":[{"id":"treatment-finding","name":"Treatment","description":"Treatment options.","questions":[{"text":"Which treatments do clinical guidelines describe?","kind":"provenance"},{"text":"Who decides on treatment with the person?","kind":"boundary"}]}]}]},{"id":"information","name":"Information","description":"Understanding.","layers":[{"id":"symptoms","name":"Symptoms","description":"What it is.","findings":[{"id":"symptoms-finding","name":"Symptoms","description":"General information.","questions":[{"text":"What does reliable health information say about depression?","kind":"provenance"},{"text":"How does it differ from sadness or grief?","kind":"definition"}]}]},{"id":"language","name":"Language","description":"Stigma.","findings":[{"id":"language-finding","name":"Language","description":"Respectful language.","questions":[{"text":"Is the language respectful and non-stigmatising?","kind":"boundary"},{"text":"Is recovery described as possible?","kind":"boundary"}]}]}]},{"id":"others","name":"Supporting others","description":"Family and friends.","layers":[{"id":"helping","name":"Helping","description":"What to do.","findings":[{"id":"helping-finding","name":"Helping","description":"Helping someone.","questions":[{"text":"How can a friend or family member help?","kind":"action"},{"text":"When should they seek urgent help?","kind":"boundary"}]}]},{"id":"rights","name":"Rights","description":"Work and study.","findings":[{"id":"rights-finding","name":"Rights","description":"Rights.","questions":[{"text":"What adjustments at work or study may be available?","kind":"boundary"},{"text":"Who can advise?","kind":"action"}]}]}]}]},"agentConduct":{"may":["Share reliable information about depression and how to find professional help.","Point a person in crisis to emergency services or crisis lines."],"mustNot":["Diagnose depression or prescribe or adjust treatment in place of a clinician.","Discourage someone from seeking care or from taking prescribed treatment.","Give information that could help a person harm themselves.","Disclose a person's mental health condition without consent."],"requiresHuman":["Contacting emergency services when a person may be at risk of self-harm.","Any change to a person's treatment."]},"ethics":{"considerations":["Depression is common and stigmatised; people deserve dignity and confidentiality.","Untreated depression can be fatal, so delay and dismissal cause harm."],"affectedParties":["People living with depression","Families and carers","Clinicians"]},"owners":{"steward":"Nobody owns the condition; each person's treating clinician answers for their care.","roles":[],"masterSystems":["Clinical classification systems of the health authority"]},"relations":[{"target":"Q11076418","type":"parent","note":"registry parent class"},{"target":"Q317309","type":"parent","note":"registry parent class"},{"target":"depressive disorder and mental health condition","type":"related","note":"category"},{"target":"psychotherapy and medication","type":"related","note":"treatment"},{"target":"health professional","type":"related","note":"assessment"},{"target":"anxiety","type":"related","note":"co-occurring"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.major-depressive-disorder","Wikidata: Q42844 (https://www.wikidata.org/wiki/Q42844)","ICD-11: 6A70-6A71 depressive episode and recurrent disorder","DSM-5: 296.2x / 296.3x major depressive disorder"]},"properties":{"applicability":"not-applicable","items":[]},"recognition":{"applicability":"optional","items":["Diagnosed with criteria such as DSM-5 or ICD-11","Severity: mild, moderate, severe","Recurrent and persistent forms","Not visible; experienced as persistent low mood, loss of interest and other symptoms."]},"capabilities":{"applicability":"required","items":["seek assessment from a doctor or mental health professional","access evidence-based treatments such as talking therapies and medication","contact crisis services when at risk","support someone who is struggling"]},"hazards":{"applicability":"required","items":["Self-diagnosis or diagnosis by an agent","Missing signs that someone is at risk of harming themselves","Stigmatising language","Stopping medication without medical advice"]},"interfaces":{"applicability":"required","items":["NICE guideline NG222 depression in adults","WHO mhGAP guidance","Mental health law and patient rights"]},"context":{"applicability":"required","items":["A recognised clinical condition, diagnosed and treated by health professionals.","single episode and recurrent depression","persistent depressive disorder","depression with melancholic or other features","perinatal depression","treatment-resistant depression"]}},"sources":[{"title":"Wikidata item Q42844: major depressive disorder","url":"https://www.wikidata.org/wiki/Q42844","note":"identity and sense of the item"},{"title":"Wikipedia: Major depressive disorder","url":"https://en.wikipedia.org/wiki/Major_depressive_disorder","note":"general description of the item"}],"openQuestions":["How should crisis contacts be localised on the page?","Should subtypes be separate entries?","How should treatment guidance be linked to authoritative sources?"],"resources":{"spec":"/models/things/publications/thing-q42844/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q42844/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-11T06:57:21Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"not-applicable","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-06T19:52:00+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass","interaction.properties":"Plane XCT: no invented physical properties."},"score":1.0}}