{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.metsulfuron-methyl","code":"thing-q4803950","url":"https://ver.cy/models/thing/q4803950/","name":"metsulfuron-methyl","alternateNames":[],"kind":"thing","status":"published","version":"0.1.0-research.1","language":"en","classifiers":{"family":"Thing Registry","category":"Physical world and living systems","entryKind":"thing","plane":"PHY","domain":["PHY.MAT"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"Metsulfuron-methyl is a sulfonylurea herbicide that inhibits plant acetolactate synthase, disrupting branched-chain amino acid biosynthesis and controlling susceptible broadleaf weeds and some grasses.","purpose":"Enable an agent to identify metsulfuron-methyl, assess the quality and condition of a particular material, and determine which handling or use decisions have sufficient evidence.","scope":{"in":["Molecular identity and verified chemical identifiers","Grade, active-substance assay, impurities, and batch evidence","Physical state, solubility, ionization, and chemical stability under recorded conditions","Herbicidal activity and evidence of plant susceptibility or resistance","Parent-substance residues, transformation, and environmental movement","Substance hazard evidence and jurisdiction-specific regulatory identity"],"out":["Commercial herbicide formulations, brands, co-formulants, and packaging","Manufacturing processes and synthesis instructions","Field application plans, spraying equipment, and operational dosage decisions","Whole-farm weed management and crop rotation planning","Independent models of metabolites, other sulfonylureas, and affected organisms"],"boundaries":[]},"distinguishingFeatures":["Require agreement with CAS 74223-64-6 and the methyl 2-(4-methoxy-6-methyl-1,3,5-triazin-2-ylcarbamoylsulfamoyl)benzoate structure; a similar herbicide name is insufficient. [FAO identity specification](https://www.fao.org/fileadmin/templates/agphome/documents/Pests_Pesticides/Specs/Metsulfuron-methyl_2011.pdf)","Check molecular connectivity, including the methyl benzoate and substituted triazine groups, when distinguishing this substance from related sulfonylureas. [FAO structural identity](https://www.fao.org/fileadmin/templates/agphome/documents/Pests_Pesticides/Specs/Metsulfuron-methyl_2011.pdf)","Use a validated identity assay and an additional independent test when identity remains uncertain; appearance alone cannot establish identity. [FAO identity testing](https://www.fao.org/fileadmin/templates/agphome/documents/Pests_Pesticides/Specs/Metsulfuron-methyl_2011.pdf)","Determine whether a record denotes the active substance, technical material containing manufacturing impurities, or a formulated mixture containing added ingredients. [FAO material specifications](https://www.fao.org/fileadmin/templates/agphome/documents/Pests_Pesticides/Specs/Metsulfuron-methyl_2011.pdf)"],"structure":{"bundles":[{"id":"chemical-identity-and-boundaries","name":"Chemical identity and boundaries","description":"Resolve the registered substance and distinguish it from related chemicals and products.","layers":[{"id":"molecular-identification","name":"Molecular identification","description":"Establish agreement between chemical names, identifiers, structure, and analytical evidence.","findings":[{"id":"metsulfuron-methyl-identity-match","name":"Metsulfuron-methyl identity match","description":"Record the evidence connecting the material to this exact molecular identity.","questions":[{"text":"Which authoritative record connects the supplied name and identifiers to the metsulfuron-methyl structure?","id":"metsulfuron-methyl-identity-match-q01","kind":"provenance"},{"text":"Which analytical result distinguishes the sample from related sulfonylureas and transformation products?","id":"metsulfuron-methyl-identity-match-q02","kind":"measurement"}]}]},{"id":"substance-material-product","name":"Substance, material, and product","description":"Locate each record at the appropriate chemical or commercial level.","findings":[{"id":"active-substance-record-boundary","name":"Active-substance record boundary","description":"Keep parent-substance identity separate from the composition and permissions of a containing product.","questions":[{"text":"Does this record identify metsulfuron-methyl itself, a technical batch, or a formulated herbicide?","id":"active-substance-record-boundary-q01","kind":"boundary"},{"text":"Which product or mixture model owns the co-formulants, other active ingredients, and label?","id":"active-substance-record-boundary-q02","kind":"boundary"}]}]}]},{"id":"assay-and-material-quality","name":"Assay and material quality","description":"Assess whether a particular material contains the expected amount and quality of metsulfuron-methyl.","layers":[{"id":"active-substance-content","name":"Active-substance content","description":"Connect measured parent-substance content to the batch and intended grade.","findings":[{"id":"batch-assay-acceptance","name":"Batch assay acceptance","description":"Judge declared and measured content against a specification whose scope covers this material.","questions":[{"text":"What metsulfuron-methyl content was measured, on which mass basis, with what uncertainty and reference standard?","id":"batch-assay-acceptance-q01","kind":"measurement"},{"text":"Which specification version and manufacturer applicability support accepting this batch for its intended grade?","id":"batch-assay-acceptance-q02","kind":"action"}]}]},{"id":"impurities-and-change","name":"Impurities and change","description":"Distinguish the initial impurity profile from changes during storage.","findings":[{"id":"material-integrity-evidence","name":"Material integrity evidence","description":"Use component measurements and storage history to assess loss of parent substance.","questions":[{"text":"Which impurities or degradants were identified and quantified, and how much material remains analytically unaccounted for?","id":"material-integrity-evidence-q01","kind":"measurement"},{"text":"Does comparison with the release assay justify continued use, retesting, or holding the material?","id":"material-integrity-evidence-q02","kind":"action"}]}]}]},{"id":"physical-state-and-chemical-stability","name":"Physical state and chemical stability","description":"Represent properties under explicit temperature, solvent, pH, and storage conditions.","layers":[{"id":"phase-and-solution-behavior","name":"Phase and solution behavior","description":"Characterize solid material and its behavior in specified liquids.","findings":[{"id":"conditioned-property-record","name":"Conditioned property record","description":"Attach sample quality and test conditions to thermal, solubility, and ionization measurements.","questions":[{"text":"What phase and thermal events were observed, and was decomposition distinguished from melting or boiling?","id":"conditioned-property-record-q01","kind":"measurement"},{"text":"What solubility and pKa measurements are supported for the stated solvent, pH, temperature, and material purity?","id":"conditioned-property-record-q02","kind":"measurement"}]}]},{"id":"parent-substance-stability","name":"Parent-substance stability","description":"Assess retention of chemical identity during storage and aqueous exposure.","findings":[{"id":"stability-window","name":"Stability window","description":"Define evidence-supported conditions and durations for maintaining the parent substance.","questions":[{"text":"What parent-substance loss and degradant formation were measured across pH, temperature, light, and moisture conditions?","id":"stability-window-q01","kind":"measurement"},{"text":"Which storage or solution-holding conditions are justified by those tests for the intended analytical or material use?","id":"stability-window-q02","kind":"action"}]}]}]},{"id":"plant-response-and-environmental-fate","name":"Plant response and environmental fate","description":"Connect biological response with exposure, residual parent substance, and environmental transformation.","layers":[{"id":"herbicidal-response","name":"Herbicidal response","description":"Organize mechanism, susceptibility, and resistance evidence for identified plants.","findings":[{"id":"mechanism-and-susceptibility-evidence","name":"Mechanism and susceptibility evidence","description":"Record the experimentally supported target mechanism and the limits of response predictions.","questions":[{"text":"Which studies establish acetolactate synthase inhibition by metsulfuron-methyl and connect it to the measured plant response?","id":"mechanism-and-susceptibility-evidence-q01","kind":"provenance"},{"text":"For which species, biotype, growth stage, and exposure was susceptibility or resistance demonstrated?","id":"mechanism-and-susceptibility-evidence-q02","kind":"measurement"}]}]},{"id":"residue-transformation-and-movement","name":"Residue transformation and movement","description":"Separate detection of the parent molecule from degradation and movement between environmental compartments.","findings":[{"id":"interpretable-parent-residue","name":"Interpretable parent residue","description":"EPA provides an environmental method record covering metsulfuron-methyl and degradants in water; applicability still requires examination of method performance. [EPA method record](https://www.epa.gov/pesticide-analytical-methods/ecm-metsulfuron-methyl-degradates-water-mrid-49585702)","questions":[{"text":"Does the method separately quantify parent substance and relevant degradants in this matrix, with adequate recovery and quantification limits?","id":"interpretable-parent-residue-q01","kind":"measurement"},{"text":"What evidence distinguishes degradation from sorption, leaching, runoff, or other explanations for declining parent concentration?","id":"interpretable-parent-residue-q02","kind":"boundary"}]}]}]},{"id":"hazards-and-action-constraints","name":"Hazards and action constraints","description":"Connect material-specific hazard evidence and current regulatory decisions to proposed actions.","layers":[{"id":"hazard-evidence","name":"Hazard evidence","description":"Keep human-health and environmental endpoints tied to the tested material and exposure.","findings":[{"id":"applicable-hazard-profile","name":"Applicable hazard profile","description":"Record substantiated classifications and endpoints without transferring mixture findings automatically to the parent substance.","questions":[{"text":"Which current classifications and toxicity or ecotoxicity endpoints apply to this grade of metsulfuron-methyl, including effects on non-target plants?","id":"applicable-hazard-profile-q01","kind":"provenance"},{"text":"Which documented exposure limits and controls apply to the proposed handling conditions, and which remain unestablished?","id":"applicable-hazard-profile-q02","kind":"action"}]}]},{"id":"jurisdiction-and-permitted-action","name":"Jurisdiction and permitted action","description":"Resolve current substance decisions and the product-level conditions needed for a specific action.","findings":[{"id":"authorization-evidence-chain","name":"Authorization evidence chain","description":"Link the registered substance to dated official decisions and the relevant containing-product record.","questions":[{"text":"Which official decision establishes the substance's status in the intended jurisdiction on the proposed action date?","id":"authorization-evidence-chain-q01","kind":"provenance"},{"text":"Which linked product authorization, label conditions, residue rules, or disposal requirements govern the proposed action?","id":"authorization-evidence-chain-q02","kind":"action"}]}]}]},{"id":"evidence-and-external-alignment","name":"Evidence and external alignment","description":"What the world already says about this thing, gathered so the model can be checked against it.","layers":[{"id":"reported-evidence","name":"Reported evidence","description":"Findings from the breadth pass, kept separate from the structural claims.","findings":[{"id":"evidence-confidence-notes","name":"Check these first","description":"Recalled without web access and unsourced; every item is a lead to verify.","questions":[{"text":"Which of these check these first hold for the sense of metsulfuron-methyl this model covers, and on what evidence?","id":"evidence-confidence-notes-q01","kind":"provenance"}]},{"id":"evidence-identifiers","name":"Identifiers and schemes","description":"Recalled without web access and unsourced; every item is a lead to verify.","questions":[{"text":"Which of these identifiers and schemes hold for the sense of metsulfuron-methyl this model covers, and on what evidence?","id":"evidence-identifiers-q01","kind":"provenance"}]},{"id":"evidence-standards-and-regulation","name":"Standards and regulation","description":"Recalled without web access and unsourced; every item is a lead to verify.","questions":[{"text":"Which of these standards and regulation hold for the sense of metsulfuron-methyl this model covers, and on what evidence?","id":"evidence-standards-and-regulation-q01","kind":"provenance"}]},{"id":"evidence-real-world-use","name":"Real-world use","description":"Recalled without web access and unsourced; every item is a lead to verify.","questions":[{"text":"Which of these real-world use hold for the sense of metsulfuron-methyl this model covers, and on what evidence?","id":"evidence-real-world-use-q01","kind":"provenance"}]},{"id":"evidence-measurements","name":"Typical measurements","description":"Recalled without web access and unsourced; every item is a lead to verify.","questions":[{"text":"Which of these typical measurements hold for the sense of metsulfuron-methyl this model covers, and on what evidence?","id":"evidence-measurements-q01","kind":"provenance"}]},{"id":"evidence-failure-modes-and-hazards","name":"Failure modes and hazards","description":"Recalled without web access and unsourced; every item is a lead to verify.","questions":[{"text":"Which of these failure modes and hazards hold for the sense of metsulfuron-methyl this model covers, and on what evidence?","id":"evidence-failure-modes-and-hazards-q01","kind":"provenance"}]},{"id":"evidence-regional-variation","name":"Regional variation","description":"Recalled without web access and unsourced; every item is a lead to verify.","questions":[{"text":"Which of these regional variation hold for the sense of metsulfuron-methyl this model covers, and on what evidence?","id":"evidence-regional-variation-q01","kind":"provenance"}]},{"id":"evidence-neighbours","name":"Neighbouring kinds and how to tell them apart","description":"Recalled without web access and unsourced; every item is a lead to verify.","questions":[{"text":"Which of these neighbouring kinds and how to tell them apart hold for the sense of metsulfuron-methyl this model covers, and on what evidence?","id":"evidence-neighbours-q01","kind":"provenance"}]}]}]}]},"agentConduct":{"may":["Describe metsulfuron-methyl's class, mode of action and approved uses.","Report its effects on non-target plants and its regulatory status."],"mustNot":["Apply or recommend applying it where it is not approved.","Spray near crops, gardens or water where drift can damage them.","Advise use without the protective equipment and records the law requires.","Suggest using it to damage a neighbour's plants or property."],"requiresHuman":["Any application or disposal decision on land."]},"ethics":{"considerations":["Very small amounts can damage sensitive crops and native plants far from the target field."],"affectedParties":["Neighbouring growers","Native plants and ecosystems","Farm workers"]},"owners":{"steward":"The person or business that holds it; pesticide regulators control approval and disposal.","roles":[],"masterSystems":["National pesticide registers"]},"relations":[{"target":"Q11173","type":"parent","note":"registry parent class"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.metsulfuron-methyl","Wikidata: Q4803950 (https://www.wikidata.org/wiki/Q4803950)"]},"properties":{"applicability":"required","items":["Chemical identifier concordance: Registry id, CAS, PubChem CID, EC identifier where verified, and structure identifier with source","Material grade: Analytical reference material, purified substance, technical material; formulation linked separately","Metsulfuron-methyl assay: g/kg or mass %, with uncertainty, method, and dry or as-received basis","Impurity and degradant profile: Named component concentrations in mg/kg or g/kg, including unidentified fraction","Physical and thermal condition: Observed phase at temperature and pressure; melting or decomposition event in °C","Solubility and ionization: Solubility in mg/L; pKa dimensionless; solvent, pH, temperature, and method","Transformation and dissipation: Rate constant in day^-1 or DT50 in days, with matrix and experimental conditions","Plant response: Endpoint-specific inhibition or injury, concentration or g active substance/ha, species, biotype, and observation time","Hazard and exposure controls: Classification authority, hazard category, material basis, exposure limit where established, jurisdiction, and date","Regulatory applicability: Authority, substance decision, effective dates, conditions, and linked product authorizations"]},"recognition":{"applicability":"required","items":["Usually supplied as water-dispersible granules; identity must be confirmed by label and registration."]},"capabilities":{"applicability":"required","items":["Resolve an incoming name or laboratory record to the verified metsulfuron-methyl identity.","Compare a batch assay and impurity profile with an applicable material specification.","Calculate parent-substance mass from material quantity and measured assay.","Assess whether storage or aqueous-exposure evidence justifies retesting for degradation.","Interpret residue and plant-response measurements within their analytical and biological limits.","Determine which current substance controls and linked product conditions must be consulted before an action."]},"hazards":{"applicability":"required","items":["Drift or runoff injures non-target plants at low doses.","Persistence in soil can harm following crops.","Can reach groundwater in light soils."]},"interfaces":{"applicability":"required","items":["Regulation (EC) No 1107/2009 concerning the placing of plant protection products on the market, European Union."]},"context":{"applicability":"required","items":["Metsulfuron-methyl is encountered as an active ingredient in herbicide formulations used to control susceptible broadleaf weeds and some grasses.","It is used in agricultural and land management settings where the authorized product uses and vegetation sensitivity support its selection.","Material assessment distinguishes the chemical substance from formulated products with different concentrations and additional ingredients."]}},"sources":[{"title":"Wikidata item Q4803950: metsulfuron-methyl","url":"https://www.wikidata.org/wiki/Q4803950","note":"identity and sense of the item"},{"title":"Wikipedia: Metsulfuron-methyl","url":"https://en.wikipedia.org/wiki/Metsulfuron-methyl","note":"general description of the item"}],"openQuestions":["Which verified PubChem and EC records should complete the identifier crosswalk, and does the existing Vercy catalogue already contain a model to reuse?","Which current quality specifications and impurity limits apply to each supported manufacturer and grade?","Which primary measurements should anchor solubility, pKa, thermal behavior, and hydrolysis under defined conditions?","Which plant-response, resistance, environmental-fate, and degradant studies are sufficiently applicable to support decisions beyond laboratory conditions?","Which jurisdictions and intended actions must the first researched version cover, and what current classifications, exposure limits, and authorizations apply there?"],"resources":{"spec":"/models/things/publications/thing-q4803950/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q4803950/spec.json"],"providers":["Codex"],"researchStatus":"unreviewed","generatedAt":"2026-09-12T11:18:50Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"filled","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-07T10:10:31+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass"},"score":1.0}}