{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.stilbenoid","code":"thing-q526360","url":"https://ver.cy/models/thing/q526360/","name":"stilbenoid","alternateNames":["stilbene dye","pawhuskin C","5-[2-(3,4-Dihydroxyphenyl)ethenyl]-2-(3,7-dimethylocta-2,6-dienyl)benzene-1,3-diol","5-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]-2-(3,7-dimethylocta-2,6-dien-1-yl)benzene-1,3-diol","pawhuskin A","11-[2-(3,5-Dihydroxyphenyl)ethenyl]-8b,14a-dihydrophenanthro[10,9-b][1,4]benzodioxine-2,4,6,7-tetrol","[3-Acetyloxy-5-[2-(2,4,6,7-tetraacetyloxy-8b,14a-dihydrophenanthro[9,10-b][1,4]benzodioxin-11-yl)ethenyl]phenyl] acetate","2-(3-Methyl-2-butenyl)-5-methoxystilbene-3,4'-diol","3-(3,4-Dimethoxyphenyl)-2-(3-hydroxy-4-methoxycarbonylphenyl)prop-2-enoic acid","3,4',5-Trimethoxy-4-prenylstilbene","2-[2-(3-Formyl-4-hydroxyphenyl)ethenyl]-4,6-dihydroxybenzaldehyde","3,5-Dimethoxy-4-prenylstilbene"],"kind":"thing","status":"published","version":"0.2.0-wave.2","language":"en","classifiers":{"family":"Thing Registry","category":"Physical world and living systems","entryKind":"thing","plane":"PHY","domain":["PHY.MAT"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"A class of natural phenolic compounds based on a stilbene skeleton of two aromatic rings joined by an ethene bridge, including resveratrol, pterostilbene, piceatannol and plant stilbenoids such as pawhuskins, produced by plants as defence compounds; stilbenoids are studied for biological activities, used in some dyes, and are the subject of health claims requiring careful evaluation.","purpose":"Let an agent explain stilbenoids, their structure, sources and biological activities, and evaluate health claims about compounds such as resveratrol with evidence.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Stilbene skeleton","Plant defence compounds","Phenolic","Bioactivity claims"],"structure":{"bundles":[{"id":"chemistry","name":"Chemistry","description":"Structure and sources.","layers":[{"id":"structure","name":"Structure","description":"Skeleton and biosynthesis.","findings":[{"id":"structure-finding","name":"Structure","description":"Structure.","questions":[{"text":"What is the structure of this stilbenoid, and how do plants biosynthesise it?","kind":"provenance"},{"text":"How do cis and trans isomers differ?","kind":"definition"}]}]},{"id":"sources","name":"Sources","description":"Plant sources.","findings":[{"id":"sources-finding","name":"Sources","description":"Sources.","questions":[{"text":"Which plants produce this stilbenoid, and why?","kind":"provenance"},{"text":"How much is present in foods such as grapes and peanuts?","kind":"measurement"}]}]}]},{"id":"activity","name":"Activity","description":"Biological effects.","layers":[{"id":"research","name":"Research","description":"Research findings.","findings":[{"id":"research-finding","name":"Research","description":"Research.","questions":[{"text":"What do laboratory and clinical studies say about this stilbenoid effects, with attribution?","kind":"provenance"},{"text":"How strong is the human evidence?","kind":"boundary"}]}]},{"id":"claims","name":"Claims","description":"Health claims.","findings":[{"id":"claims-finding","name":"Claims","description":"Health claims.","questions":[{"text":"Is this health claim for resveratrol or another stilbenoid supported and authorised?","kind":"boundary"},{"text":"Is the user asking for advice on treating a condition?","kind":"boundary"}]}]}]},{"id":"uses","name":"Uses","description":"Applications.","layers":[{"id":"supplements","name":"Supplements","description":"Supplements.","findings":[{"id":"supplements-finding","name":"Supplements","description":"Supplements.","questions":[{"text":"How are stilbenoid supplements regulated, and what quality issues arise?","kind":"provenance"},{"text":"Which interactions or cautions apply, according to authorities?","kind":"provenance"}]}]},{"id":"dyes","name":"Dyes","description":"Stilbene dyes and brighteners.","findings":[{"id":"dyes-finding","name":"Dyes","description":"Dyes.","questions":[{"text":"How are synthetic stilbene compounds used as dyes and optical brighteners?","kind":"provenance"},{"text":"Which safety rules apply?","kind":"provenance"}]}]}]},{"id":"learn","name":"Learn","description":"Study.","layers":[{"id":"databases","name":"Databases","description":"Natural product data.","findings":[{"id":"databases-finding","name":"Databases","description":"Databases.","questions":[{"text":"Which databases record stilbenoids and their sources?","kind":"provenance"},{"text":"How are they identified analytically?","kind":"provenance"}]}]},{"id":"teach","name":"Teach","description":"Teaching.","findings":[{"id":"teach-finding","name":"Teach","description":"Teaching.","questions":[{"text":"How can stilbenoids be taught within phenolic chemistry?","kind":"action"},{"text":"Which misconceptions arise?","kind":"provenance"}]}]}]}]},"agentConduct":{"may":["Explain stilbenoid chemistry, sources and research findings with citations.","State clearly the difference between laboratory findings and proven effects in people."],"mustNot":["Claim that a stilbenoid supplement prevents or cures disease without approved evidence.","Recommend doses of supplements to individuals.","Ignore interactions of supplements with medicines when discussing them.","Present animal or cell studies as proof of effects in humans."],"requiresHuman":["Any advice to a patient to take or stop a supplement."]},"ethics":{"considerations":["Supplements are sold on overstated claims that can delay real treatment.","People on medicines can be harmed by interactions."],"affectedParties":["Consumers of supplements","Patients on medicines","Researchers"]},"owners":{"steward":"Nobody: a class of natural compounds; makers of supplements answer for their products.","roles":[],"masterSystems":[]},"relations":[{"target":"Q2896816","type":"parent","note":"registry parent class"},{"target":"Q3561192","type":"parent","note":"registry parent class"},{"target":"Q417181","type":"parent","note":"registry parent class"},{"target":"phenylpropanoid","type":"related","note":"category"},{"target":"benzylidene compound","type":"related","note":"category"},{"target":"heterocyclic compound","type":"related","note":"other natural products"},{"target":"drug","type":"related","note":"supplement and drug research"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.stilbenoid","Wikidata: Q526360 (https://www.wikidata.org/wiki/Q526360)"]},"properties":{"applicability":"required","items":["Melting temperature:  degrees Celsius - Measure the identified compound by thermal analysis or a melting point method because different stilbenoids and solid forms have different values.","Mass solubility:  grams per litre - Measure the equilibrium dissolved concentration of the identified compound in a specified solvent at a stated temperature and pH.","Molar mass:  grams per mole - Calculate the value from the molecular formula of the identified stilbenoid because the class has no single molar mass."]},"recognition":{"applicability":"required","items":["Stilbene backbone","Phenolic plant compounds","Flavonoids have a different ring system","Not visible; compounds in plants, sometimes as crystalline solids."]},"capabilities":{"applicability":"required","items":["explain stilbenoid structure and biosynthesis","identify sources and examples","summarise biological activities with attribution","evaluate health claims"]},"hazards":{"applicability":"required","items":["Unsupported health claims","Confusing stilbenoids with flavonoids","Supplement quality problems"]},"interfaces":{"applicability":"required","items":["Supplement and health claim regulations","Chemical safety regulations"]},"context":{"applicability":"required","items":["Natural products chemistry, plant science and nutrition.","resveratrol and its derivatives","pterostilbene and piceatannol","oligomeric stilbenoids","prenylated stilbenoids such as pawhuskins","stilbene dyes (synthetic relatives)"]}},"sources":[{"title":"Wikidata item Q526360: stilbenoid","url":"https://www.wikidata.org/wiki/Q526360","note":"identity and sense of the item"},{"title":"Wikipedia: Stilbenoid","url":"https://en.wikipedia.org/wiki/Stilbenoid","note":"general description of the item"}],"openQuestions":["Should resveratrol be a separate entry?","How should natural product databases be linked?","How should claim evidence be tracked?"],"resources":{"spec":"/models/things/publications/thing-q526360/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q526360/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-11T20:51:21Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"filled","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-07T10:10:31+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass"},"score":1.0}}