{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.cellular-transport","code":"thing-q6151736","url":"https://ver.cy/models/thing/q6151736/","name":"cellular transport","alternateNames":["intracellular auxin transport","transmembrane transport","small-molecule transmembrane transport","cytosol to Golgi apparatus transport","xenobiotic transmembrane transport","ion transmembrane transport","xenobiotic export","carbon dioxide transmembrane transport","pyrimidine-containing compound transmembrane transport","polyol transport","vitamin transmembrane transport","organic acid transmembrane transport"],"kind":"thing","status":"research-draft","version":"0.2.0-wave.1","language":"en","classifiers":{"family":"Thing Registry","category":"Activities and processes","entryKind":"thing","plane":"ACT","domain":["ACT.PRC"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"The movement of substances into, out of and within cells, including transmembrane transport of ions and small molecules by diffusion, channels, carriers and pumps, vesicular transport between organelles such as from the cytosol to the Golgi apparatus, and specialised transport such as auxin movement in plants and export of xenobiotics.","purpose":"Let an agent explain cellular transport mechanisms, classify transport types, relate them to physiology and pharmacology, and support learning and research.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Occurs at cellular scale","Passive or active","Membrane or vesicular","Highly regulated"],"structure":{"bundles":[{"id":"classify","name":"Classify","description":"Type of transport.","layers":[{"id":"type","name":"Type","description":"Passive or active.","findings":[{"id":"type-finding","name":"Type","description":"Transport type.","questions":[{"text":"Is this transport passive, facilitated or active, and what drives it?","kind":"definition"},{"text":"Which proteins are involved?","kind":"provenance"}]}]},{"id":"route","name":"Route","description":"Membrane or vesicle.","findings":[{"id":"route-finding","name":"Route","description":"Route.","questions":[{"text":"Does the substance cross the membrane directly or travel in vesicles?","kind":"definition"},{"text":"Which organelles are involved?","kind":"definition"}]}]}]},{"id":"mechanism","name":"Mechanism","description":"How it works.","layers":[{"id":"gradients","name":"Gradients","description":"Driving forces.","findings":[{"id":"gradients-finding","name":"Gradients","description":"Driving forces.","questions":[{"text":"How do concentration and electrical gradients drive transport?","kind":"definition"},{"text":"How do pumps use ATP?","kind":"definition"}]}]},{"id":"regulation","name":"Regulation","description":"Control.","findings":[{"id":"regulation-finding","name":"Regulation","description":"Regulation.","questions":[{"text":"How is this transporter regulated?","kind":"provenance"},{"text":"What happens when it is defective?","kind":"provenance"}]}]}]},{"id":"applications","name":"Applications","description":"Medicine and plants.","layers":[{"id":"drugs","name":"Drugs","description":"Pharmacology.","findings":[{"id":"drugs-finding","name":"Drugs","description":"Pharmacology.","questions":[{"text":"How do transporters affect drug uptake, distribution and resistance?","kind":"provenance"},{"text":"Which drug interactions involve transporters?","kind":"provenance"}]}]},{"id":"plants","name":"Plants","description":"Plant transport.","findings":[{"id":"plants-finding","name":"Plants","description":"Plant transport.","questions":[{"text":"How is auxin transported between plant cells?","kind":"definition"},{"text":"Why does polar transport matter for growth?","kind":"definition"}]}]}]},{"id":"learn","name":"Learn","description":"Study and data.","layers":[{"id":"ontology","name":"Ontology","description":"GO terms.","findings":[{"id":"ontology-finding","name":"Ontology","description":"GO terms.","questions":[{"text":"Which Gene Ontology term describes this transport process?","kind":"provenance"},{"text":"Which genes are annotated to it?","kind":"provenance"}]}]},{"id":"teach","name":"Teach","description":"Teaching.","findings":[{"id":"teach-finding","name":"Teach","description":"Teaching.","questions":[{"text":"How can membrane transport be taught with models and experiments?","kind":"action"},{"text":"Which misconceptions are common?","kind":"provenance"}]}]}]}]},"agentConduct":{"may":["Explain cellular transport mechanisms from biology textbooks.","Summarize published research for a reader, citing the sources."],"mustNot":["Claim that a treatment works by altering cellular transport without evidence.","Give medical advice based on simplified cell biology.","Misrepresent unsettled research as established."],"requiresHuman":["Using research findings to guide treatment of a patient."]},"ethics":{"considerations":["Simplified cell biology is often misused to sell supplements and cures.","Many drugs act on cell transport; errors in explanation can mislead patients."],"affectedParties":["Students and readers","Patients"]},"owners":{"steward":"Nobody owns the process; the scientific community maintains the knowledge.","roles":[],"masterSystems":[]},"relations":[{"target":"Q1435575","type":"parent","note":"registry parent class"},{"target":"transport","type":"related","note":"category"},{"target":"endocytosis","type":"related","note":"kind"},{"target":"cell membrane","type":"related","note":"structure"},{"target":"hydrolysis","type":"related","note":"ATP hydrolysis powers pumps"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.cellular-transport","Wikidata: Q6151736 (https://www.wikidata.org/wiki/Q6151736)","Gene Ontology: GO:0006810 transport and children ontology"]},"properties":{"applicability":"not-applicable","items":[]},"recognition":{"applicability":"optional","items":["Membrane channels and pumps","Vesicles budding and fusing","Bulk transport in blood is not cellular transport","Not visible directly; shown in diagrams of membranes, channels and vesicles."]},"capabilities":{"applicability":"required","items":["classify a transport process","explain passive and active transport","relate transporters to drugs and diseases","find gene ontology terms"]},"hazards":{"applicability":"required","items":["Confusing passive and active transport","Transporter defects causing disease","Drug interactions via transporters"]},"interfaces":{"applicability":"required","items":["Gene Ontology and transporter classification systems"]},"context":{"applicability":"required","items":["Cell biology, physiology and pharmacology.","passive diffusion and facilitated diffusion","active transport by pumps","vesicular transport and endocytosis","intracellular trafficking","plant hormone transport"]}},"sources":[],"openQuestions":["Should each transport type be a separate entry?","How should transporter databases be linked?","How should plant transport be linked?"],"resources":{"spec":"/models/things/publications/thing-q6151736/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q6151736/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-11T15:32:53Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"not-applicable","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"missing"},"notes":{"interaction.properties":"Plane ACT: no invented physical properties.","sources":"Written from model knowledge without web access; claims are unverified."},"score":0.938}}