{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.hepatitis-b","code":"thing-q6853","url":"https://ver.cy/models/thing/q6853/","name":"hepatitis B","alternateNames":["hepatitis D","chronic hepatitis B","chronic hepatitis D","Lábrea fever"],"kind":"thing","status":"published","version":"0.2.0-wave.3","language":"en","classifiers":{"family":"Thing Registry","category":"Cross-cutting context","entryKind":"thing","plane":"XCT","domain":["XCT.QLT"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"A viral infection of the liver caused by the hepatitis B virus, transmitted through blood, sexual contact and from mother to child at birth, which may be acute and self-limiting or become chronic, especially when acquired in infancy, leading over decades to cirrhosis and liver cancer, and which can be complicated by co-infection with the hepatitis D virus, a defective virus that requires hepatitis B surface proteins for infectious particle assembly and transmission but not for replication of its RNA, and causes severe forms such as the Labrea fever of the Amazon; hepatitis B is preventable by vaccination and treatable with antiviral drugs.","purpose":"Let an agent explain hepatitis B and its course in neutral clinical terms, relay transmission, prevention, testing and treatment from public health and hepatology sources, describe hepatitis D co-infection, and route people at risk or with symptoms to testing and clinicians.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Blood-borne and perinatal","Chronic carriage","Vaccine-preventable","Hepatitis D dependence"],"structure":{"bundles":[{"id":"help","name":"Help","description":"Testing and care first.","layers":[{"id":"testing","name":"Testing","description":"Who should test.","findings":[{"id":"testing-finding","name":"Testing","description":"Testing.","questions":[{"text":"Why do people with risk exposures, or from high-prevalence regions, or with symptoms such as jaundice, need testing and clinical care?","kind":"action"},{"text":"Is the user asking about their own exposure or result, which needs a clinician?","kind":"boundary"}]}]},{"id":"living","name":"Living","description":"Living with hepatitis B.","findings":[{"id":"living-finding","name":"Living","description":"Living.","questions":[{"text":"What support and monitoring do people with chronic hepatitis B receive, and how is stigma addressed?","kind":"provenance"},{"text":"Is the presentation free of stigma?","kind":"boundary"}]}]}]},{"id":"understand","name":"Understand","description":"The disease.","layers":[{"id":"course","name":"Course","description":"Course.","findings":[{"id":"course-finding","name":"Course","description":"Course.","questions":[{"text":"How does hepatitis B progress from acute infection to chronic disease, cirrhosis and cancer?","kind":"definition"},{"text":"Is the question about hepatitis B, hepatitis D or another hepatitis?","kind":"boundary"}]}]},{"id":"transmission","name":"Transmission","description":"Transmission.","findings":[{"id":"transmission-finding","name":"Transmission","description":"Transmission.","questions":[{"text":"How is hepatitis B transmitted, and how does hepatitis D depend on it?","kind":"definition"},{"text":"Which entry fits hepatitis D?","kind":"action"}]}]}]},{"id":"prevent","name":"Prevent","description":"Prevention and treatment.","layers":[{"id":"vaccine","name":"Vaccine","description":"Vaccination.","findings":[{"id":"vaccine-finding","name":"Vaccine","description":"Vaccine.","questions":[{"text":"How do vaccination, birth-dose programmes and screening prevent hepatitis B, according to WHO?","kind":"provenance"},{"text":"Which references are standard?","kind":"provenance"}]}]},{"id":"treatment","name":"Treatment","description":"Treatment.","findings":[{"id":"treatment-finding","name":"Treatment","description":"Treatment.","questions":[{"text":"How are chronic hepatitis B and hepatitis D treated with antivirals and newer drugs, in general terms?","kind":"provenance"},{"text":"Which sources are cited?","kind":"provenance"}]}]}]},{"id":"context","name":"Context","description":"Epidemiology and research.","layers":[{"id":"epidemiology","name":"Epidemiology","description":"Epidemiology.","findings":[{"id":"epidemiology-finding","name":"Epidemiology","description":"Epidemiology.","questions":[{"text":"Where is hepatitis B most common, and what are elimination targets, with data attributed?","kind":"provenance"},{"text":"Which entry fits viral hepatitis elimination?","kind":"action"}]}]},{"id":"research","name":"Research","description":"Research.","findings":[{"id":"research-finding","name":"Research","description":"Research.","questions":[{"text":"What research pursues a cure for hepatitis B and treatments for hepatitis D?","kind":"provenance"},{"text":"Which entry fits hepatitis B virus?","kind":"action"}]}]}]}]},"agentConduct":{"may":["Explain hepatitis B, its transmission and prevention by vaccination, citing health authorities.","Point people to testing and treatment services."],"mustNot":["Disclose a person's hepatitis B status without consent.","Diagnose infection or advise on treatment for an individual.","Spread myths that stigmatize people with the infection.","Discourage vaccination against scientific evidence."],"requiresHuman":["Any advice affecting treatment of a pregnant person or newborn."]},"ethics":{"considerations":["People with hepatitis B face stigma and discrimination in work and migration.","Vaccination and testing access are unequal across the world."],"affectedParties":["People living with hepatitis B","Newborns","Health workers"]},"owners":{"steward":"Nobody owns the disease; public health authorities track it.","roles":[],"masterSystems":["Notifiable disease surveillance systems"]},"relations":[{"target":"Q19000567","type":"parent","note":"registry parent class"},{"target":"Q1983841","type":"parent","note":"registry parent class"},{"target":"viral hepatitis","type":"related","note":"in registry terms"},{"target":"Hepadnaviridae infectious disease","type":"related","note":"in registry terms"},{"target":"hepatitis B virus","type":"related","note":"of the Hepadnaviridae"},{"target":"hepatitis B vaccine","type":"related","note":"in infancy and at-risk groups"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.hepatitis-b","Wikidata: Q6853 (https://www.wikidata.org/wiki/Q6853)","ICD-11: 1E51.0 chronic hepatitis B","MeSH: D006509 hepatitis B"]},"properties":{"applicability":"not-applicable","items":["people with chronic infection: about 250 million - WHO estimates","annual deaths: about 1 million - mostly cirrhosis and cancer","vaccine introduced: 1982 year","hepatitis D discovered: 1977 year"]},"recognition":{"applicability":"optional","items":["Liver infection by hepatitis B virus","Acute and chronic hepatitis B, hepatitis D co-infection and superinfection, Labrea fever","Hepatitis A and E spread by food and water; hepatitis C is a different blood-borne virus","Not a visible object; jaundice in some acute cases, often silent."]},"capabilities":{"applicability":"required","items":["explain the disease and course","relay prevention and treatment","describe hepatitis D","route to testing and care"]},"hazards":{"applicability":"required","items":["Agents giving personal medical advice","Stigma toward people living with hepatitis B","Missed diagnosis of silent chronic infection"]},"interfaces":{"applicability":"required","items":["WHO guidelines on hepatitis B prevention, testing and treatment","Universal infant vaccination programmes","Blood donation screening rules","Notifiable disease reporting"]},"context":{"applicability":"required","items":["Not applicable; a disease.","acute hepatitis B","chronic hepatitis B","hepatitis D co-infection and superinfection including chronic hepatitis D","severe regional forms such as Labrea fever","occult and resolved infection","hepatitis B genotypes"]}},"sources":[{"title":"Wikidata item Q6853: hepatitis B","url":"https://www.wikidata.org/wiki/Q6853","note":"identity and sense of the item"},{"title":"Wikipedia: Hepatitis B","url":"https://en.wikipedia.org/wiki/Hepatitis_B","note":"general description of the item"}],"openQuestions":["Should hepatitis D be a separate primary entry?","How should public health guidelines be linked?","The registry entry has merged hepatitis D aliases; should they be split off?"],"resources":{"spec":"/models/things/publications/thing-q6853/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q6853/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-13T05:44:28Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"not-applicable","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-07T10:10:32+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass","interaction.properties":"Plane XCT: no invented physical properties."},"score":1.0}}