{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.alkaloid","code":"thing-q70702","url":"https://ver.cy/models/thing/q70702/","name":"alkaloid","alternateNames":[],"kind":"thing","status":"published","version":"0.2.0-wave.1","language":"en","classifiers":{"family":"Thing Registry","category":"Physical world and living systems","entryKind":"thing","plane":"PHY","domain":["PHY.MAT"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"A large class of naturally occurring nitrogen-containing organic compounds, mostly produced by plants and some fungi and animals, many with strong physiological effects, such as caffeine, nicotine, quinine, morphine, atropine and strychnine; some are medicines and many are toxic.","purpose":"Let an agent explain alkaloids by structure, sources, effects and uses at a general level, route poisoning to emergency help, and decline extraction, synthesis or misuse instructions.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Contain basic nitrogen","Natural origin","Strong biological effects","Many are toxic or controlled"],"structure":{"bundles":[{"id":"emergency","name":"Emergency","description":"Poisoning.","layers":[{"id":"poisoning","name":"Poisoning","description":"Exposure.","findings":[{"id":"poisoning-finding","name":"Poisoning","description":"Poisoning.","questions":[{"text":"Has someone, especially a child, eaten a poisonous plant or concentrated product?","kind":"boundary"},{"text":"Should a poison centre or emergency services be contacted now?","kind":"action"}]}]},{"id":"caffeine","name":"Caffeine","description":"Overdose.","findings":[{"id":"caffeine-finding","name":"Caffeine","description":"Caffeine overdose.","questions":[{"text":"Has someone taken caffeine powder or tablets in large amounts?","kind":"boundary"},{"text":"Should emergency help be sought immediately?","kind":"action"}]}]}]},{"id":"science","name":"Science","description":"Chemistry and biology.","layers":[{"id":"structure","name":"Structure","description":"Classes.","findings":[{"id":"structure-finding","name":"Structure","description":"Structural classes.","questions":[{"text":"Which structural class does this alkaloid belong to?","kind":"definition"},{"text":"Which plant produces it?","kind":"provenance"}]}]},{"id":"effects","name":"Effects","description":"Pharmacology.","findings":[{"id":"effects-finding","name":"Effects","description":"Effects.","questions":[{"text":"How does this alkaloid act on the body, in general terms, according to pharmacology sources?","kind":"provenance"},{"text":"Is the user asking about personal use or dosing?","kind":"boundary"}]}]}]},{"id":"uses","name":"Uses","description":"Medicine and food.","layers":[{"id":"medicine","name":"Medicine","description":"Medicinal alkaloids.","findings":[{"id":"medicine-finding","name":"Medicine","description":"Medicines.","questions":[{"text":"Which medicines are based on alkaloids, according to official sources?","kind":"provenance"},{"text":"How are they regulated?","kind":"provenance"}]}]},{"id":"food","name":"Food","description":"Contaminants.","findings":[{"id":"food-finding","name":"Food","description":"Food contaminants.","questions":[{"text":"Which alkaloid contaminants are limited in food, and at what levels?","kind":"provenance"},{"text":"Which authority sets them?","kind":"provenance"}]}]}]},{"id":"limits","name":"Limits","description":"Agent conduct.","layers":[{"id":"extraction","name":"Extraction","description":"No instructions.","findings":[{"id":"extraction-finding","name":"Extraction","description":"Extraction limits.","questions":[{"text":"Does the request seek extraction, synthesis or concentration of an alkaloid?","kind":"boundary"},{"text":"How should the agent decline and offer safety information?","kind":"action"}]}]},{"id":"claims","name":"Claims","description":"Health claims.","findings":[{"id":"claims-finding","name":"Claims","description":"Health claims.","questions":[{"text":"Is a claimed health benefit of an alkaloid-containing product supported by evidence?","kind":"boundary"},{"text":"Which regulator evaluates it?","kind":"provenance"}]}]}]}]},"agentConduct":{"may":["Describe alkaloids, their sources and their general effects, citing pharmacological sources.","Report hazard and legal status information for named alkaloids."],"mustNot":["Provide procedures, quantities or sources for extracting or making controlled or toxic alkaloids.","Advise a person on doses of alkaloid drugs or plant preparations.","Help anyone poison a person or animal.","Present toxic plants or extracts as safe remedies."],"requiresHuman":["Any recommendation on medical use of an alkaloid for a specific person."]},"ethics":{"considerations":["Many alkaloids are both vital medicines and deadly poisons or addictive drugs.","Indigenous knowledge of alkaloid plants has often been taken without consent or benefit."],"affectedParties":["Patients and drug users","Children at risk of poisoning","Indigenous communities"]},"owners":{"steward":"Nobody owns the class; drug control and medicines authorities regulate controlled and medicinal alkaloids.","roles":[],"masterSystems":[]},"relations":[{"target":"Q12765009","type":"parent","note":"registry parent class"},{"target":"Q206229","type":"parent","note":"registry parent class"},{"target":"organic nitrogen compound","type":"related","note":"category"},{"target":"caffeine","type":"related","note":"example"},{"target":"plant","type":"related","note":"source"},{"target":"pharmacology and toxicology","type":"related","note":"fields"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.alkaloid","Wikidata: Q70702 (https://www.wikidata.org/wiki/Q70702)"]},"properties":{"applicability":"required","items":["Molar mass:  g/mol - Molar mass is calculated from the molecular formula of the identified alkaloid and its specified chemical form.","Melting temperature:  degrees Celsius - Melting behavior is measured by thermal analysis or a melting point apparatus and depends on the compound, salt form and purity.","Water solubility:  g/L - Solubility is measured at a stated temperature and pH because alkaloid identity and protonation strongly affect the result."]},"recognition":{"applicability":"required","items":["Nitrogen-containing ring structures","Found in plants such as coffee, tobacco and poppies","Not all bitter plant compounds are alkaloids","Usually colourless, bitter crystalline solids when isolated; mostly encountered within plants."]},"capabilities":{"applicability":"required","items":["describe what alkaloids are and where they occur","find information on medicinal uses in general terms","identify poisonous plants and what to do after exposure","find regulatory status of controlled alkaloids"]},"hazards":{"applicability":"required","items":["Poisoning from plants or concentrated products","Facilitating extraction or misuse","Unsupported herbal health claims"]},"interfaces":{"applicability":"required","items":["UN drug control conventions for controlled alkaloids","Medicines regulation","Food contaminant limits such as for tropane and pyrrolizidine alkaloids"]},"context":{"applicability":"required","items":["Pharmacology, toxicology, botany and chemistry.","purine alkaloids such as caffeine","tropane alkaloids such as atropine","opium alkaloids","indole alkaloids","pyrrolizidine alkaloids"]}},"sources":[{"title":"Wikidata item Q70702: alkaloid","url":"https://www.wikidata.org/wiki/Q70702","note":"identity and sense of the item"},{"title":"Wikipedia: Alkaloid","url":"https://en.wikipedia.org/wiki/Alkaloid","note":"general description of the item"}],"openQuestions":["Should alkaloid families be separate entries?","How should toxicology data be linked?","How should controlled status be tracked?"],"resources":{"spec":"/models/things/publications/thing-q70702/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q70702/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-11T13:11:21Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"filled","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-07T10:10:32+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass"},"score":1.0}}