{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.gene","code":"thing-q7187","url":"https://ver.cy/models/thing/q7187/","name":"gene","alternateNames":[],"kind":"thing","status":"published","version":"0.2.0-wave.2","language":"en","classifiers":{"family":"Thing Registry","category":"Physical world and living systems","entryKind":"thing","plane":"PHY","domain":["PHY.OBJ"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"A unit of heredity consisting of a sequence of DNA, or RNA in some viruses, that encodes a functional product such as a protein or RNA and is passed from parents to offspring, located on chromosomes, plasmids or nonchromosomal viral genomes, regulated in expression and varying between individuals as alleles; genes are the subject of genetics and genomics, are catalogued in databases, and inform medicine, agriculture and biotechnology under ethical and legal frameworks.","purpose":"Let an agent explain genes and how they work, describe inheritance and variation, relate genes to health and biotechnology at a general level, and route personal genetic questions to professionals.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Hereditary unit","Encodes products","Alleles and variation","Regulated expression"],"structure":{"bundles":[{"id":"understand","name":"Understand","description":"What genes are.","layers":[{"id":"structure","name":"Structure","description":"Structure and function.","findings":[{"id":"structure-finding","name":"Structure","description":"Structure.","questions":[{"text":"What is a gene, how is it structured with regulatory and coding regions, and how does it encode a product?","kind":"definition"},{"text":"How is the concept of the gene debated among biologists?","kind":"boundary"}]}]},{"id":"inherit","name":"Inherit","description":"Inheritance and variation.","findings":[{"id":"inherit-finding","name":"Inherit","description":"Inheritance.","questions":[{"text":"How are genes inherited, and how do alleles and mutations create variation?","kind":"definition"},{"text":"Which entry fits a specific gene?","kind":"action"}]}]}]},{"id":"health","name":"Health","description":"Genes and health.","layers":[{"id":"disease","name":"Disease","description":"Genetic conditions.","findings":[{"id":"disease-finding","name":"Disease","description":"Conditions.","questions":[{"text":"How do gene variants relate to genetic conditions and disease risk, according to medical genetics?","kind":"provenance"},{"text":"Is the user asking about their own genetic results, which needs a genetic counsellor or clinician?","kind":"boundary"}]}]},{"id":"testing","name":"Testing","description":"Genetic testing.","findings":[{"id":"testing-finding","name":"Testing","description":"Testing.","questions":[{"text":"How does genetic testing work, and which privacy and discrimination protections apply?","kind":"provenance"},{"text":"Which entry fits genetic testing?","kind":"action"}]}]}]},{"id":"apply","name":"Apply","description":"Biotechnology.","layers":[{"id":"engineering","name":"Engineering","description":"Genetic modification and editing.","findings":[{"id":"engineering-finding","name":"Engineering","description":"Engineering.","questions":[{"text":"How are genes cloned, modified and edited in research, agriculture and medicine, and how is this regulated?","kind":"provenance"},{"text":"What are the attributed positions in ethical debates?","kind":"provenance"}]}]},{"id":"databases","name":"Databases","description":"Gene databases.","findings":[{"id":"databases-finding","name":"Databases","description":"Databases.","questions":[{"text":"Which databases catalogue genes, and how are genes named?","kind":"provenance"},{"text":"How can a gene be looked up?","kind":"action"}]}]}]},{"id":"learn","name":"Learn","description":"History and teaching.","layers":[{"id":"history","name":"History","description":"History of the gene.","findings":[{"id":"history-finding","name":"History","description":"History.","questions":[{"text":"How did the concept of the gene develop from Mendel to molecular biology and genomics?","kind":"provenance"},{"text":"Which references are standard?","kind":"provenance"}]}]},{"id":"teach","name":"Teach","description":"Teaching.","findings":[{"id":"teach-finding","name":"Teach","description":"Teaching.","questions":[{"text":"How can genes and inheritance be taught while avoiding genetic determinism?","kind":"action"},{"text":"Which misconceptions arise?","kind":"provenance"}]}]}]}]},"agentConduct":{"may":["Explain what genes are and how inheritance works from reputable sources.","Distinguish genetic influence from genetic determination."],"mustNot":["Interpret a person's own genetic results as medical advice.","Claim that genes fix intelligence, behaviour or worth.","Share a person's genetic data without consent.","Assist genetic modification outside lawful, approved settings."],"requiresHuman":["Using genetic data in insurance, employment or medical decisions."]},"ethics":{"considerations":["Genetic determinism has fuelled discrimination and eugenics.","Genetic data reveal facts about relatives who did not consent."],"affectedParties":["People tested","Their relatives","Groups stereotyped by ancestry"]},"owners":{"steward":"Nobody owns a gene; data controllers answer for genetic data.","roles":[],"masterSystems":["Gene and sequence databases"]},"relations":[{"target":"Q3771876","type":"parent","note":"registry parent class"},{"target":"nucleic acid structure","type":"related","note":"category"},{"target":"gene expression","type":"related","note":"how genes act"},{"target":"DNA-binding protein","type":"related","note":"regulators of genes"},{"target":"cloning","type":"related","note":"molecular cloning of genes"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.gene","Wikidata: Q7187 (https://www.wikidata.org/wiki/Q7187)"]},"properties":{"applicability":"required","items":["Sequence length:  nucleotides - Length is determined from an identified sequence using stated gene boundaries and specifying whether introns and other included regions are counted.","Guanine and cytosine content:  percent - Content is calculated as the percentage of identified nucleotides that are guanine or cytosine within the stated gene sequence."]},"recognition":{"applicability":"required","items":["DNA sequence encoding a product","Inherited and variable","A chromosome carries many genes; a genome is the full set","Not visible; sequences within DNA."]},"capabilities":{"applicability":"required","items":["explain gene structure and function","describe inheritance and variation","relate to health and biotechnology","route personal questions"]},"hazards":{"applicability":"required","items":["Genetic determinism","Agents giving personal genetic advice","Privacy risks with genetic data"]},"interfaces":{"applicability":"required","items":["Gene nomenclature standards","Genetic data protection and discrimination laws","Regulation of genetic testing and modification"]},"context":{"applicability":"required","items":["Units of heredity.","protein-coding genes","non-coding RNA genes","regulatory genes","genes by organism","pseudogenes and mobile elements"]}},"sources":[{"title":"Wikidata item Q7187: gene","url":"https://www.wikidata.org/wiki/Q7187","note":"identity and sense of the item"},{"title":"Wikipedia: Gene","url":"https://en.wikipedia.org/wiki/Gene","note":"general description of the item"}],"openQuestions":["Should each gene be a separate entry?","How should gene databases be linked?","How should ethical frameworks be linked?"],"resources":{"spec":"/models/things/publications/thing-q7187/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q7187/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-12T00:04:30Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"filled","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-08T18:54:40+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass"},"score":1.0}}