{"schema":"https://ver.cy/schemas/card/1.0.0","id":"vr.tr.amino-acid","code":"thing-q8066","url":"https://ver.cy/models/thing/q8066/","name":"amino acid","alternateNames":["Valines","aminopolycarboxylic acid","hexaacetic acid","N-formylkynurenine","timonacic","proteinogenic amino acid","L-Asparagine","telluromethionine","(R)-timonacic","(S)-timonacic","L-lysine","DL-glutamine"],"kind":"thing","status":"published","version":"0.2.0-wave.1","language":"en","classifiers":{"family":"Thing Registry","category":"Physical world and living systems","entryKind":"thing","plane":"PHY","domain":["PHY.MAT"],"industry":[],"navPath":"","tags":[],"facets":{}},"whatItIs":"An organic compound containing an amino group and a carboxylic acid group; about 20 proteinogenic amino acids are the building blocks of proteins, and many others have biological or industrial roles.","purpose":"Let an agent handle amino acids by structure, classification, biological role, nutrition and supplements, with care about health claims.","scope":{"in":[],"out":[],"boundaries":[]},"distinguishingFeatures":["Amino plus carboxylic acid group","Chiral (except glycine)","Build proteins","Some are essential in diet"],"structure":{"bundles":[{"id":"structure","name":"Structure","description":"Which amino acid.","layers":[{"id":"identity","name":"Identity","description":"Name and code.","findings":[{"id":"identity-finding","name":"Identity","description":"Identity.","questions":[{"text":"Which amino acid is meant, and what is its code?","kind":"definition"},{"text":"What is its side chain?","kind":"definition"}]}]},{"id":"class","name":"Class","description":"Polarity and charge.","findings":[{"id":"class-finding","name":"Class","description":"Classification.","questions":[{"text":"Is it polar, nonpolar, acidic or basic?","kind":"definition"},{"text":"Is it essential?","kind":"definition"}]}]}]},{"id":"biology","name":"Biology","description":"Roles.","layers":[{"id":"proteins","name":"Proteins","description":"Building blocks.","findings":[{"id":"proteins-finding","name":"Proteins","description":"Protein role.","questions":[{"text":"How does it contribute to protein structure?","kind":"definition"},{"text":"Which codons encode it?","kind":"definition"}]}]},{"id":"metabolism","name":"Metabolism","description":"Other roles.","findings":[{"id":"metabolism-finding","name":"Metabolism","description":"Metabolic roles.","questions":[{"text":"What other roles does it have, such as neurotransmitter precursor?","kind":"definition"},{"text":"Which pathways?","kind":"provenance"}]}]}]},{"id":"nutrition","name":"Nutrition","description":"Diet.","layers":[{"id":"sources","name":"Sources","description":"Foods.","findings":[{"id":"sources-finding","name":"Sources","description":"Dietary sources.","questions":[{"text":"Which foods provide it?","kind":"definition"},{"text":"What does dietary guidance say about protein?","kind":"provenance"}]}]},{"id":"disorders","name":"Disorders","description":"Inborn errors.","findings":[{"id":"disorders-finding","name":"Disorders","description":"Metabolic disorders.","questions":[{"text":"Is a metabolic disorder such as PKU relevant?","kind":"boundary"},{"text":"Who manages the diet?","kind":"action"}]}]}]},{"id":"supplements","name":"Supplements","description":"Claims.","layers":[{"id":"claims","name":"Claims","description":"Evidence.","findings":[{"id":"claims-finding","name":"Claims","description":"Supplement claims.","questions":[{"text":"Is a claimed benefit authorised or supported by evidence?","kind":"provenance"},{"text":"Which authority assessed it?","kind":"provenance"}]}]},{"id":"safety","name":"Safety","description":"Intake.","findings":[{"id":"safety-finding","name":"Safety","description":"Supplement safety.","questions":[{"text":"Are there safe upper intake levels?","kind":"measurement"},{"text":"Should a doctor or dietitian be consulted?","kind":"boundary"}]}]}]}]},"agentConduct":{"may":["Describe the structure, properties and biological roles of amino acids from reliable sources.","Report the amino acid content of foods with their sources."],"mustNot":["Make health or performance claims for amino acid supplements that evidence does not support.","Give dietary advice for a person's medical condition, such as a metabolic disorder, in place of a clinician.","Misstate the hazards of handling amino acids or their derivatives in a laboratory."],"requiresHuman":["Recommending supplementation to a person with a medical condition."]},"ethics":{"considerations":["Supplement marketing often overstates benefits and can mislead consumers.","People with inherited metabolic disorders depend on accurate dietary information."],"affectedParties":["Consumers of supplements","People with metabolic disorders"]},"owners":{"steward":"Nobody owns the substance class; producers answer for products and food authorities regulate claims.","roles":[],"masterSystems":["Chemical substance databases"]},"relations":[{"target":"Q167198","type":"parent","note":"registry parent class"},{"target":"Q421948","type":"parent","note":"registry parent class"},{"target":"amine and organic acid","type":"related","note":"category"},{"target":"protein","type":"related","note":"polymer"},{"target":"peptide bond","type":"related","note":"bond"},{"target":"nutrition","type":"related","note":"diet"}],"interaction":{"identity":{"applicability":"required","items":["Vercy registry: vr.tr.amino-acid","Wikidata: Q8066 (https://www.wikidata.org/wiki/Q8066)","IUPAC codes: three- and one-letter codes amino acids","ChEBI id: database ids chemical entities"]},"properties":{"applicability":"required","items":["Molar mass:  grams per mole - Molar mass is calculated from the molecular formula, distinguishing the free amino acid from salts and hydrates.","Water solubility:  grams per liter - Water solubility is measured at a stated temperature and pH because it varies substantially with molecular structure and ionization.","Solid density:  grams per cubic centimeter - Solid density is measured for a specified crystalline form and temperature using a suitable density measurement method."]},"recognition":{"applicability":"required","items":["Amino and carboxyl groups","Three- and one-letter codes such as Val and V","Proteinogenic and non-proteinogenic kinds","White crystalline solids when pure."]},"capabilities":{"applicability":"required","items":["classify amino acids","explain protein structure","understand essential amino acids in diet","assess supplement claims"]},"hazards":{"applicability":"required","items":["Unsupported supplement claims","Metabolic disorders such as PKU needing diet control","Excess intake from supplements"]},"interfaces":{"applicability":"required","items":["IUPAC-IUBMB nomenclature","Food supplement regulations","Health claims rules (EU Regulation 1924/2006)"]},"context":{"applicability":"required","items":["Building proteins, metabolism, signalling and nutrition.","proteinogenic amino acids","essential amino acids","non-proteinogenic amino acids","amino acid derivatives"]}},"sources":[{"title":"Wikidata item Q8066: amino acid","url":"https://www.wikidata.org/wiki/Q8066","note":"identity and sense of the item"},{"title":"Wikipedia: Amino acid","url":"https://en.wikipedia.org/wiki/Amino_acid","note":"general description of the item"}],"openQuestions":["Should each amino acid be a separate entry?","How should databases be linked?","How should supplement claims be assessed?"],"resources":{"spec":"/models/things/publications/thing-q8066/spec.json"},"provenance":{"origin":"thing registry research (pass 2)","builtFrom":["models/things/publications/thing-q8066/spec.json"],"providers":["Claude"],"researchStatus":"unreviewed","generatedAt":"2026-09-11T08:23:30Z","builder":"tools/build_cards.py@1.0.0"},"completeness":{"sections":{"classifiers":"filled","whatItIs":"filled","purpose":"filled","distinguishingFeatures":"filled","structure":"filled","agentConduct":"filled","ethics":"filled","owners":"filled","relations":"filled","interaction.identity":"filled","interaction.properties":"filled","interaction.recognition":"filled","interaction.capabilities":"filled","interaction.hazards":"filled","interaction.interfaces":"filled","interaction.context":"filled","sources":"filled"},"notes":{"_gate":"Published through the thing publication gate 1.0 on 2026-10-07T10:10:32+00:00: completeness 1.00; sense: Wikidata description; 2 live sources; review by codex: pass"},"score":1.0}}