infection
the pathological state resulting from the invasion of the body by pathogenic microorganisms
Research draft, second pass
A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.
written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify
Researched by: Claude
Purpose and description
Let an agent explain infection as a pathological state, describe kinds by pathogen and site, relay prevention, diagnosis and treatment principles from public health sources, and route personal symptoms to clinicians and emergencies to urgent care.
The pathological state resulting from the invasion and multiplication of pathogenic microorganisms such as bacteria, viruses, fungi, protozoa and parasites in the body, ranging from localised to systemic disease, with examples including malaria and its severe form blackwater fever, amoebiasis, and complications of vaccination such as progressive vaccinia; infections are transmitted by contact, air, water, food and vectors, are diagnosed by clinical and laboratory methods and are treated with antimicrobials and supportive care.
What it is for: Not applicable; a pathological state.
It can be explain the concept and kinds; relay transmission and prevention; relay diagnosis and treatment principles; route personal questions.
Distinguishing features
Pathogen multiplication
Host response
Transmissibility
Antimicrobial treatment
What it looks like
Not a visible object; signs such as fever, inflammation and specific symptoms.
Physical character
deaths from infectious diseases: about 13 million per year worldwide - estimates including sepsis
How it is recognised
Disease state from pathogen invasion
Bacterial, viral, fungal, protozoal and parasitic, local and systemic
Colonisation without disease is not infection; inflammation may occur without infection
Related models
is a kind of - in registry terms
is caused by - the invading organism
is treated with - such as antibiotics
is prevented by - and hygiene
In practice
Families and kinds
bacterial infections
viral infections
fungal infections
protozoal infections such as malaria and amoebiasis
parasitic worm infections
localised and systemic infections including sepsis
healthcare-associated infections
vaccine complications such as progressive vaccinia as a historical category
Identifiers
ICD-11 chapter 1 infectious and parasitic diseases
MeSH D007239 infections
Standards and regulation
WHO and national infection control guidelines
International Health Regulations
Notifiable disease rules
Antimicrobial stewardship policies
Failure modes and hazards
Sepsis and death
Antimicrobial resistance
Agents giving personal medical advice
Outbreaks and pandemics
Analytical facets
- substance
- abstract
- origin
- conceptual
- agency
- inert
- mobility
- not-applicable
- scale
- not-applicable
- affordances
- observable
Also called
+58
Where this came from
oewn:2024 · CC BY 4.0
Drafted structure
Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.
Help Getting help first.
Safety.
Emergency
Emergency signs.
Emergency
Emergency.
- What signs of severe infection such as sepsis need emergency care? action
- Is the user describing such signs, which need emergency services now? boundary
Care
Clinical care.
Care
Care.
- How are infections diagnosed and treated, in general terms? provenance
- Is the user asking about their own symptoms, which need a clinician? boundary
Understand The state.
Clinical.
Definition
Definition and kinds.
Definition
Definition.
- What is infection, and how do kinds differ by pathogen and site? definition
- Is the question about infection, colonisation or non-infectious inflammation? boundary
Process
Infection process.
Process
Process.
- How do pathogens enter, multiply and cause disease, and how does the immune system respond? definition
- Which entry fits the specific pathogen? action
Prevent Prevention and control.
Public health.
Transmission
Transmission and prevention.
Transmission
Transmission.
- How are infections transmitted, and how are they prevented by hygiene, vaccination and vector control? provenance
- Which references are standard? provenance
Resistance
Antimicrobial resistance.
Resistance
Resistance.
- What is antimicrobial resistance, and what do reports say about its scale? provenance
- Which sources are cited? provenance
Context Epidemiology and history.
Context.
Epidemiology
Burden.
Epidemiology
Epidemiology.
- What is the global burden of infections, with sources? measurement
- Which entry fits global health? action
History
History.
History
History.
- How did germ theory and antimicrobials transform the understanding of infection? provenance
- Which entry fits the history of microbiology? action
What the second pass must settle
- Should infectious disease be the primary linked entry?
- How should public health guidance be linked?
- The registry entry has merged aliases naming specific diseases and a historical vaccine complication; should they be split off?