{ "model": { "rank": 1415, "code": "thing-pathology-state", "model_id": "vr.tr.pathology-state", "name": "pathology", "purpose": "any deviation from a healthy or normal condition", "family": "Thing Registry", "category": "Cross-cutting context", "status": "research-draft", "kind": "thing", "plane": "XCT", "domain": "XCT.STA", "industry": "", "version": "", "url": "/models/thing/pathology-state/", "tier": 2, "score": 148, "payload": { "layer": "wordnet", "aliases": [ "acidosis", "ketoacidosis", "diabetic acidosis", "metabolic acidosis", "respiratory acidosis", "carbon dioxide acidosis", "starvation acidosis", "alkalosis", "metabolic alkalosis", "respiratory alkalosis", "ankylosis", "anchylosis", "arteriectasis", "arteriectasia", "arthropathy", "asynergy", "asynergia", "asystole", "cardiac arrest", "cardiopulmonary arrest", "diverticulosis", "flux", "fluorosis", "gammopathy", "glossolalia", "angiopathy", "akinesis", "akinesia", "alalia", "cystoplegia", "cystoparalysis", "diplegia", "multiple sclerosis", "MS", "disseminated sclerosis", "disseminated multiple sclerosis", "aphagia", "aortic stenosis", "enterostenosis", "laryngostenosis" ], "aliasCount": 238, "merged": 148, "knownIn": 0, "facets": { "substance": "abstract", "origin": "conceptual", "agency": "inert", "mobility": "not-applicable", "scale": "not-applicable", "affordances": [ "observable" ] }, "markers": [], "lexicalClass": "noun.state", "senseRank": 1, "alsoRegisteredAs": null, "source": { "dataset": "oewn:2024", "synset": "oewn-14228432-n", "ili": "i111547", "license": "CC BY 4.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-12T22:59:37Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 3, "engine": "claude" }, "metaModel": { "id": "THING-PATHOLOGY-STATE", "registryId": "vr.tr.pathology-state", "name": "pathology", "version": "0.2.0-wave.3", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.STA" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/pathology-state/", "model": { "registry_id": "vr.tr.pathology-state", "name": "pathology", "purpose": "Let an agent explain the concept of a pathological state and how it relates to disease, disorder and normal variation, distinguish the state sense from pathology as a discipline, relay how states such as acidosis are defined in clinical sources, and route personal health questions to clinicians.", "definition": "In the sense recorded here, any deviation from a healthy or normal condition of the body or mind, a pathological state, as distinct from pathology as the scientific discipline; the registry entry gathers aliases for acid-base disturbances such as metabolic, respiratory and diabetic acidosis, which are examples of pathological states rather than the category itself.", "what_it_is_for": "Not applicable; a concept of abnormal condition.", "affordances": [ "explain the concept and related terms", "distinguish state from discipline", "relay clinical definitions of example states", "route personal questions to clinicians" ], "distinguishing_features": [ "Departure from normal", "Defined against reference ranges and criteria", "Structural or functional", "Basis of diagnosis" ], "appearance": "Not a visible object; recognised by signs, symptoms and test results.", "visual_identification": [ "Deviation from healthy or normal condition", "Disease, disorder, injury and disturbance as kinds", "Pathology as a discipline studies such states; normal variation is not pathological" ], "physical_properties": [], "families_and_kinds": [ "diseases and disorders", "injuries", "physiological disturbances such as acidosis, including metabolic, respiratory, diabetic and ketoacidosis", "states of mental ill-health", "subclinical and borderline states" ], "related_models": [ { "relation": "is a kind of", "target": "condition", "why": "an abnormal one" }, { "relation": "is confused with", "target": "pathology", "why": "the discipline" }, { "relation": "includes", "target": "acidosis", "why": "as an example state" }, { "relation": "is contrasted with", "target": "health", "why": "the normal condition" } ], "identifiers": [ { "scheme": "MeSH", "value_or_pattern": "D010335", "note": "pathological conditions, signs and symptoms" } ], "standards_and_regulation": [ "Clinical definitions and reference ranges", "Disease classification systems such as ICD" ], "failure_modes_and_hazards": [ "Treating normal variation as pathology", "Sense confusion with the discipline", "Agents giving personal medical advice" ], "in_scope": [], "out_of_scope": [], "characteristics": [] }, "sources": [], "structure": { "bundles": [ { "id": "concept", "name": "Concept", "description": "What a pathological state is.", "rationale": "Definition.", "layers": [ { "id": "definition", "name": "Definition", "description": "Definition and related terms.", "findings": [ { "id": "definition-finding", "name": "Definition", "description": "Definition.", "questions": [ { "text": "What is a pathological state, and how does it relate to disease, disorder and normal variation?", "kind": "definition" }, { "text": "Is the question about a pathological state or about pathology as a discipline?", "kind": "boundary" } ] } ] }, { "id": "criteria", "name": "Criteria", "description": "How abnormality is defined.", "findings": [ { "id": "criteria-finding", "name": "Criteria", "description": "Criteria.", "questions": [ { "text": "How do reference ranges and diagnostic criteria define abnormal states, and what debates exist, with positions attributed?", "kind": "provenance" }, { "text": "Is the presentation neutral?", "kind": "boundary" } ] } ] } ] }, { "id": "examples", "name": "Examples", "description": "Example states.", "rationale": "Clinical.", "layers": [ { "id": "acidosis", "name": "Acidosis", "description": "Acid-base disturbances.", "findings": [ { "id": "acidosis-finding", "name": "Acidosis", "description": "Acidosis.", "questions": [ { "text": "What are metabolic, respiratory and diabetic acidosis, in general terms?", "kind": "provenance" }, { "text": "Is the user asking about their own condition, which needs a clinician?", "kind": "boundary" } ] } ] }, { "id": "other", "name": "Other", "description": "Other states.", "findings": [ { "id": "other-finding", "name": "Other", "description": "Other.", "questions": [ { "text": "What other categories of pathological state exist, and how are they classified?", "kind": "provenance" }, { "text": "Which entry fits the specific state?", "kind": "action" } ] } ] } ] }, { "id": "practice", "name": "Practice", "description": "Diagnosis.", "rationale": "Clinical.", "layers": [ { "id": "recognition", "name": "Recognition", "description": "Recognising states.", "findings": [ { "id": "recognition-finding", "name": "Recognition", "description": "Recognition.", "questions": [ { "text": "How do clinicians recognise and confirm pathological states?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] }, { "id": "classification", "name": "Classification", "description": "Classification.", "findings": [ { "id": "classification-finding", "name": "Classification", "description": "Classification.", "questions": [ { "text": "How do ICD and other systems classify pathological states?", "kind": "provenance" }, { "text": "Which entry fits ICD?", "kind": "action" } ] } ] } ] }, { "id": "context", "name": "Context", "description": "Philosophy and history.", "rationale": "Context.", "layers": [ { "id": "philosophy", "name": "Philosophy", "description": "Philosophy of medicine.", "findings": [ { "id": "philosophy-finding", "name": "Philosophy", "description": "Philosophy.", "questions": [ { "text": "How do philosophers of medicine define disease and pathology, with positions attributed?", "kind": "provenance" }, { "text": "Which entry fits philosophy of medicine?", "kind": "action" } ] } ] }, { "id": "history", "name": "History", "description": "History.", "findings": [ { "id": "history-finding", "name": "History", "description": "History.", "questions": [ { "text": "How have concepts of pathological states changed historically?", "kind": "provenance" }, { "text": "Which sources are cited?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Should acidosis be a separate primary entry?", "How should clinical definitions be linked?", "The registry entry has merged aliases naming specific acid-base disturbances; should they be split off?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "abstract concept", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched.", "facetsInferred": false, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a pathology, record what state it is in, and decide what may be done with it.", "whatItIs": "any deviation from a healthy or normal condition", "characteristics": { "substance": "abstract", "origin": "conceptual", "agency": "inert" }, "whatYouCanDoWithIt": [ "observed and measured" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: acidosis, ketoacidosis, diabetic acidosis, metabolic acidosis, respiratory acidosis, carbon dioxide acidosis, starvation acidosis, alkalosis, metabolic alkalosis, respiratory alkalosis, ankylosis, anchylosis.", "148 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a pathology, and on what evidence are they told apart?" ], "whatItIsMadeOf": "an abstraction with no physical instance", "physicalCharacter": [ "Does nothing on its own; everything it does, something else did to it." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state" ], "howItIsRecognised": [ "Nothing to see. What is recognised is an instance of it, and which instances count is exactly what is argued about." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "acidosis", "ketoacidosis", "diabetic acidosis", "metabolic acidosis", "respiratory acidosis", "carbon dioxide acidosis", "starvation acidosis", "alkalosis", "metabolic alkalosis", "respiratory alkalosis", "ankylosis", "anchylosis" ] } ], "standing": "148 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one pathology from another, and a pathology from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a pathology, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a pathology, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a pathology is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a pathology, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a pathology, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a pathology is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a pathology sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a pathology, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a pathology, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a pathology is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a pathology from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a pathology, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a pathology, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a pathology is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a pathology passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a pathology between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a pathology, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a pathology, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a pathology is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a pathology, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a pathology is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a pathology, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a pathology, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a pathology is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "definitions-in-contest", "name": "Definitions and who holds them", "description": "What pathology is taken to mean, and by whom.", "rationale": "When a field disagrees about a concept, the disagreement is the content. A model that picks one definition silently destroys the information.", "layers": [ { "id": "competing-definitions", "name": "Competing definitions", "description": "The main readings and the traditions behind them.", "findings": [ { "id": "definition-map", "name": "Definitions and their holders", "description": "Each definition with the school or body that holds it.", "questions": [ { "id": "definition-map-q01", "text": "Which definitions of pathology are in use, and which tradition or body holds each?", "kind": "definition" }, { "id": "definition-map-q02", "text": "What turns on the difference between them in practice?", "kind": "boundary" } ] } ] }, { "id": "operationalisation", "name": "Operationalisation", "description": "How it is measured or applied when it has to be.", "findings": [ { "id": "operational-record", "name": "Measures and proxies", "description": "Instruments and indicators used to stand in for it.", "questions": [ { "id": "operational-record-q01", "text": "How is pathology operationalised or measured in practice, and by what instrument?", "kind": "measurement" }, { "id": "operational-record-q02", "text": "What does that operationalisation leave out, and when does that matter?", "kind": "boundary" } ] } ] } ] }, { "id": "instances-and-use", "name": "Instances, use and consequence", "description": "What counts as an instance of pathology and what follows from calling something that.", "rationale": "Applying a concept is an act with consequences, so a model must say what the label licenses and what it does not.", "layers": [ { "id": "instances", "name": "What counts as an instance", "description": "Clear cases, borderline cases and non-cases.", "findings": [ { "id": "instance-tests", "name": "Tests for an instance", "description": "What would settle whether something falls under it.", "questions": [ { "id": "instance-tests-q01", "text": "What would settle whether something is an instance of pathology?", "kind": "boundary" }, { "id": "instance-tests-q02", "text": "Which borderline cases are argued about, and on what grounds?", "kind": "definition" } ] } ] }, { "id": "consequence", "name": "Consequence of application", "description": "Rights, duties or decisions that follow from the label.", "findings": [ { "id": "consequence-record", "name": "What the label licenses", "description": "What an agent may do once something is classified this way.", "questions": [ { "id": "consequence-record-q01", "text": "What follows practically once something is treated as pathology?", "kind": "action" }, { "id": "consequence-record-q02", "text": "What must an agent not infer from the label alone?", "kind": "action" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a pathology came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a pathology and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a pathology, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a pathology, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a pathology is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a pathology is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a pathology, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a pathology, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a pathology is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 5, "layers": 10, "findings": 12, "questions": 32 } } } }