{ "model": { "rank": 2290, "code": "thing-q11085", "model_id": "vr.tr.parkinson-s-disease", "name": "Parkinson's disease", "purpose": "Let an agent explain Parkinson disease in general terms with attribution to medical sources, describe symptoms, diagnosis, treatments and support as documented, and route personal questions to clinicians.", "family": "Thing Registry", "category": "Cross-cutting context", "status": "research-draft", "kind": "thing", "plane": "XCT", "domain": "XCT.STA", "industry": "", "version": "", "url": "/models/thing/q11085/", "tier": 2, "score": 110, "payload": { "layer": "wikidata", "aliases": [ "Parkinson’s disease dementia", "dopamine dysregulation syndrome", "young-onset Parkinson disease", "Parkinson’s disease psychosis", "late-onset Parkinson disease", "Parkinson disease, mitochondrial", "PARK16", "Parkinson disease 22, autosomal dominant; PARK22", "Parkinson's disease 3" ], "aliasCount": 9, "merged": 9, "knownIn": 110, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q11085", "url": "https://www.wikidata.org/wiki/Q11085", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-12T02:02:12Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 2, "engine": "claude" }, "metaModel": { "id": "THING-Q11085", "registryId": "vr.tr.parkinson-s-disease", "name": "Parkinson's disease", "version": "0.2.0-wave.2", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.STA" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q11085/", "model": { "registry_id": "vr.tr.parkinson-s-disease", "name": "Parkinson's disease", "purpose": "Let an agent explain Parkinson disease in general terms with attribution to medical sources, describe symptoms, diagnosis, treatments and support as documented, and route personal questions to clinicians.", "definition": "A progressive neurodegenerative disorder characterised by tremor, slowness of movement, rigidity and postural instability, with non-motor features such as sleep disturbance, mood changes, and in some people cognitive decline, psychosis or dopamine dysregulation, caused by loss of dopamine-producing neurons and the accumulation of alpha-synuclein, in young-onset, late-onset and genetic forms; the disease is managed with medication, therapies and sometimes surgery, and this entry gives general information only, not personal medical advice.", "what_it_is_for": "A neurodegenerative movement disorder.", "affordances": [ "explain the condition generally", "describe diagnosis and treatment", "point to support", "route personal questions" ], "distinguishing_features": [ "Progressive", "Motor and non-motor features", "Alpha-synuclein pathology", "Treatable symptoms" ], "appearance": "Not visible as a disease; motor signs observed clinically.", "visual_identification": [ "Tremor, slowness, rigidity", "Dopamine neuron loss", "Parkinsonism from other causes and essential tremor are distinct" ], "physical_properties": [], "families_and_kinds": [ "typical late-onset Parkinson disease", "young-onset Parkinson disease", "genetic and mitochondrial forms", "Parkinson disease with dementia or psychosis", "related syndromes such as dopamine dysregulation" ], "related_models": [ { "relation": "is a kind of", "target": "synucleinopathy", "why": "category" }, { "relation": "is related to", "target": "thought disorder", "why": "psychiatric features" }, { "relation": "is related to", "target": "memory", "why": "cognitive changes" }, { "relation": "is related to", "target": "psychologist", "why": "supporting care" } ], "identifiers": [], "standards_and_regulation": [ "Clinical guidelines from neurology bodies", "Drug regulation for treatments", "Disability and care support frameworks" ], "failure_modes_and_hazards": [ "Agents giving personal medical advice", "Misinformation about cures", "Stigma" ], "in_scope": [], "out_of_scope": [], "characteristics": [] }, "sources": [], "structure": { "bundles": [ { "id": "understand", "name": "Understand", "description": "What Parkinson disease is.", "rationale": "General information.", "layers": [ { "id": "features", "name": "Features", "description": "Symptoms and course.", "findings": [ { "id": "features-finding", "name": "Features", "description": "Features.", "questions": [ { "text": "What are the motor and non-motor features of Parkinson disease, and how does it progress, according to medical sources?", "kind": "provenance" }, { "text": "Is the user asking about their own or a relative health, which needs a clinician?", "kind": "boundary" } ] } ] }, { "id": "causes", "name": "Causes", "description": "Causes and forms.", "findings": [ { "id": "causes-finding", "name": "Causes", "description": "Causes.", "questions": [ { "text": "What is known about causes, including genetics, environment and alpha-synuclein, and how do young-onset and late-onset forms differ?", "kind": "provenance" }, { "text": "Which entry fits a specific form?", "kind": "action" } ] } ] } ] }, { "id": "care", "name": "Care", "description": "Diagnosis and treatment.", "rationale": "Medicine.", "layers": [ { "id": "diagnosis", "name": "Diagnosis", "description": "Diagnosis.", "findings": [ { "id": "diagnosis-finding", "name": "Diagnosis", "description": "Diagnosis.", "questions": [ { "text": "How is Parkinson disease diagnosed and distinguished from other causes of parkinsonism, in general terms?", "kind": "provenance" }, { "text": "Which specialists are involved?", "kind": "provenance" } ] } ] }, { "id": "treatment", "name": "Treatment", "description": "Treatments.", "findings": [ { "id": "treatment-finding", "name": "Treatment", "description": "Treatments.", "questions": [ { "text": "What treatments are documented, including medication, therapies and deep brain stimulation, and what complications such as dopamine dysregulation are described?", "kind": "provenance" }, { "text": "Which entry fits a specific treatment?", "kind": "action" } ] } ] } ] }, { "id": "support", "name": "Support", "description": "Living with the disease.", "rationale": "Support.", "layers": [ { "id": "support", "name": "Support", "description": "Support resources.", "findings": [ { "id": "support-finding", "name": "Support", "description": "Support.", "questions": [ { "text": "What support exists for people with Parkinson disease and carers, and what do organisations offer?", "kind": "provenance" }, { "text": "Is someone in crisis, needing urgent help?", "kind": "boundary" } ] } ] }, { "id": "daily", "name": "Daily", "description": "Daily life.", "findings": [ { "id": "daily-finding", "name": "Daily", "description": "Daily life.", "questions": [ { "text": "What is documented about exercise, nutrition and daily living with the disease?", "kind": "provenance" }, { "text": "Which entry fits neurological rehabilitation?", "kind": "action" } ] } ] } ] }, { "id": "learn", "name": "Learn", "description": "Research and history.", "rationale": "Education.", "layers": [ { "id": "research", "name": "Research", "description": "Research.", "findings": [ { "id": "research-finding", "name": "Research", "description": "Research.", "questions": [ { "text": "What are current research directions, and which claims are premature?", "kind": "provenance" }, { "text": "Which findings are contested?", "kind": "boundary" } ] } ] }, { "id": "history", "name": "History", "description": "History.", "findings": [ { "id": "history-finding", "name": "History", "description": "History.", "questions": [ { "text": "How was the disease described by James Parkinson, and how has understanding developed?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Should each form be a separate entry?", "How should guidelines be linked?", "How should support organisations be linked?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "disease or condition", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a Parkinson's disease, record what state it is in, and decide what may be done with it.", "whatItIs": "Let an agent explain Parkinson disease in general terms with attribution to medical sources, describe symptoms, diagnosis, treatments and support as documented, and route personal questions to clinicians.", "characteristics": { "substance": "abstract", "origin": "conceptual", "agency": "inert" }, "whatYouCanDoWithIt": [ "observed and measured" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: Parkinson’s disease dementia, dopamine dysregulation syndrome, young-onset Parkinson disease, Parkinson’s disease psychosis, late-onset Parkinson disease, Parkinson disease, mitochondrial, PARK16, Parkinson disease 22, autosomal dominant; PARK22, Parkinson's disease 3.", "9 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.", "Described in 110 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a Parkinson's disease, and on what evidence are they told apart?" ], "whatItIsMadeOf": "an abstraction with no physical instance", "physicalCharacter": [ "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state" ], "howItIsRecognised": [ "Recognised by criteria applied to signs and findings, not by appearance. Two conditions can look identical and be distinguished only by test." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "Parkinson’s disease dementia", "dopamine dysregulation syndrome", "young-onset Parkinson disease", "Parkinson’s disease psychosis", "late-onset Parkinson disease", "Parkinson disease, mitochondrial", "PARK16", "Parkinson disease 22, autosomal dominant; PARK22", "Parkinson's disease 3" ] } ], "standing": "Described in 110 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 9 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one Parkinson's disease from another, and a Parkinson's disease from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a Parkinson's disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a Parkinson's disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a Parkinson's disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a Parkinson's disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a Parkinson's disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a Parkinson's disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a Parkinson's disease sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a Parkinson's disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a Parkinson's disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a Parkinson's disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a Parkinson's disease from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a Parkinson's disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a Parkinson's disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a Parkinson's disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a Parkinson's disease passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a Parkinson's disease between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a Parkinson's disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a Parkinson's disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a Parkinson's disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a Parkinson's disease, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a Parkinson's disease is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a Parkinson's disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a Parkinson's disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a Parkinson's disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "diagnosis-and-criteria", "name": "Diagnosis, criteria and coding", "description": "What makes a case of Parkinson's disease a case, and under which revision.", "rationale": "Criteria change between revisions, so a diagnosis without its coding revision cannot be compared with a later one.", "layers": [ { "id": "criteria", "name": "Diagnostic criteria", "description": "The criteria in force and who issues them.", "findings": [ { "id": "criteria-record", "name": "Criteria, issuer and revision", "description": "What must be true for a diagnosis, according to whom.", "questions": [ { "id": "criteria-record-q01", "text": "What criteria define Parkinson's disease, issued by which body, in which revision?", "kind": "definition" }, { "id": "criteria-record-q02", "text": "What changed between revisions that would reclassify existing cases?", "kind": "boundary" } ] } ] }, { "id": "coding", "name": "Coding and terminology", "description": "The codes used to record it and their mapping.", "findings": [ { "id": "coding-record", "name": "Codes and mappings", "description": "Which classification codes apply and how they map.", "questions": [ { "id": "coding-record-q01", "text": "Which classification and terminology codes cover Parkinson's disease, and how do they map to each other?", "kind": "definition" }, { "id": "coding-record-q02", "text": "What is lost when a case is mapped from one scheme to another?", "kind": "boundary" } ] } ] } ] }, { "id": "course-and-population", "name": "Course, population and care", "description": "How Parkinson's disease develops, whom it affects, and what is done about it.", "rationale": "The condition, the diagnosis and the episode of care are three different things, and an agent must not merge them.", "layers": [ { "id": "course", "name": "Course and stages", "description": "Onset, progression, remission and outcome.", "findings": [ { "id": "course-record", "name": "Stages and transitions", "description": "The stages recorded and what moves a case between them.", "questions": [ { "id": "course-record-q01", "text": "What course does Parkinson's disease typically take, and what marks each stage?", "kind": "definition" }, { "id": "course-record-q02", "text": "What separates the condition itself from an episode of care for it?", "kind": "boundary" } ] } ] }, { "id": "population", "name": "Affected populations", "description": "Who is affected, how often, and on what evidence.", "findings": [ { "id": "epidemiology", "name": "Prevalence and its basis", "description": "Rates with their population, period and source.", "questions": [ { "id": "epidemiology-q01", "text": "What prevalence or incidence is reported for Parkinson's disease, in which population and period?", "kind": "measurement" }, { "id": "epidemiology-q02", "text": "What may an agent not conclude about an individual from a population rate?", "kind": "action" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a Parkinson's disease came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a Parkinson's disease and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a Parkinson's disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a Parkinson's disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a Parkinson's disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a Parkinson's disease is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a Parkinson's disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a Parkinson's disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a Parkinson's disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 5, "layers": 10, "findings": 12, "questions": 32 } } } }