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Research draft

protoplasm

vr.tr.protoplasm · PHY.LIV

Let an agent explain protoplasm as a historical and ontological term, relay its relation to cytoplasm, cytosol and nucleus from cell biology references, describe its use in histology for specific cell types, and distinguish protoplasm from cytoplasm, from the cell as a whole and from outdated vitalist meanings.

Thing Registry Physical world and living systems

Research draft, second pass

A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.

written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify

Researched by: Claude

Purpose and description

Let an agent explain protoplasm as a historical and ontological term, relay its relation to cytoplasm, cytosol and nucleus from cell biology references, describe its use in histology for specific cell types, and distinguish protoplasm from cytoplasm, from the cell as a whole and from outdated vitalist meanings.

The living contents of a cell, comprising the cytoplasm and, in eukaryotes, the nucleus, bounded by the cell membrane, a term coined in the 19th century when the jelly-like substance of cells was regarded as the physical basis of life and applied to specific cell types such as neuron, Schwann cell, muscle, epithelial, mesenchymal and mesothelial cell protoplasm; in modern cell biology the term is largely replaced by cytoplasm, cytosol and nucleoplasm, but it survives in histology and in some ontologies.

What it is for: Not applicable; a cell biology concept.

It can be explain the term and its history; relay relation to modern terms; describe histological use; distinguish related terms.

Distinguishing features

Historical term

Includes nucleus

Cell type specific uses

Vitalist origins

What it looks like

Not a visible object without microscopy; the living contents of a cell.

Physical character

term coined: 1839 year - Purkinje, popularised by von Mohl

water content: about 70-80 percent - typical

modern equivalents: cytoplasm plus nucleoplasm note

How it is recognised

Living contents of a cell

Protoplasm of neurons, Schwann cells, muscle, epithelial, mesenchymal and mesothelial cells

Cytoplasm excludes the nucleus; cytosol is the fluid; the cell includes the membrane and wall

Related models

is a kind of - in registry terms

cell part

is a kind of - in registry terms

cellular component

comprises - and the nucleus

cytoplasm

was coined by - in 1839

Jan Evangelista Purkyne

In practice

Families and kinds

protoplasm in the historical sense as the basis of life

protoplasm as cytoplasm plus nucleoplasm

cell type specific protoplasm in histology such as neuron, Schwann cell, muscle, epithelial, mesenchymal and mesothelial cell protoplasm

protoplasm in plant cell biology and protoplasts

Identifiers

GO GO:0005622 intracellular anatomical structure, modern equivalent

Standards and regulation

No regulation; cell ontology conventions

Failure modes and hazards

Treating protoplasm as a current scientific concept

Confusing protoplasm with cytoplasm

Registry aliases splitting the term by cell type

Also called

muscle cell protoplasmprotoplasm of schwann cellprotoplasm of neuronprotoplasm of epithelial cellprotoplasm of mesenchymal cellProtoplasm of mesothelial cellProtoplasm of nonkeratinized cell of epidermisProtoplasm of pancreatic ductal cellProtoplasm of acinar cell of pancreasProtoplasm of pancreatic centro-acinar cellProtoplasm of hemal cellProtoplasm of stem cellProtoplasm of connective tissue cellProtoplasm of neural cell

Where this came from

wikidata · CC0 1.0

Also registered as vr.tr.protoplasm

Drafted structure

Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.

Understand What protoplasm is.

Science.

Definition

Definition.

Definition

Definition.

  1. What is protoplasm, and how does it relate to cytoplasm, cytosol, nucleus and the cell? definition
  2. Is the question about the historical term, modern cell contents or a specific cell type? boundary

Composition

Composition.

Composition

Composition.

  1. What does protoplasm consist of, in water, proteins, organelles and inclusions? definition
  2. Which entry fits cytoplasm? action
History History.

Attribution.

Origins

Origins.

Origins

Origins.

  1. How did Purkinje, von Mohl and Huxley develop the protoplasm concept, and what did it mean for vitalism? provenance
  2. Which references are standard? provenance

Decline

Decline of the term.

Decline

Decline.

  1. Why did cytoplasm and other terms replace protoplasm in the 20th century? provenance
  2. Which sources are cited? provenance
Use Current uses.

Science.

Histology

Histology.

Histology

Histology.

  1. How is protoplasm still used in histology for cell types such as neurons, Schwann, muscle and epithelial cells? provenance
  2. Which entry fits the specific cell type? action

Plants

Plants and protoplasts.

Plants

Plants.

  1. How are protoplasm and protoplasts used in plant biology? provenance
  2. Which entry fits protoplast? action
Context Culture and ontology.

Context.

Ontology

Ontologies.

Ontology

Ontology.

  1. How do cell ontologies represent cell contents today? provenance
  2. Which entry fits Gene Ontology cellular component? action

Culture

Culture.

Culture

Culture.

  1. How did protoplasm figure in popular science and fiction? provenance
  2. Which entry fits the history of cell theory? action

What the second pass must settle

  • Should cytoplasm be the primary linked entry?
  • How should cell biology references be linked?
  • The registry entry has merged aliases naming cell type specific protoplasm; should they be split off?