{
    "model": {
        "rank": 8599,
        "code": "thing-q1141499",
        "model_id": "vr.tr.ehlers-danlos-syndrome",
        "name": "Ehlers-Danlos syndrome",
        "purpose": "Let an agent explain Ehlers-Danlos syndromes and their types, relay general information on diagnosis, management and support from expert bodies, describe living with the condition, and route personal medical questions to clinicians.",
        "family": "Thing Registry",
        "category": "Cross-cutting context",
        "status": "research-draft",
        "kind": "thing",
        "plane": "XCT",
        "domain": "XCT.STA",
        "industry": "",
        "version": "",
        "url": "/models/thing/q1141499/",
        "tier": 2,
        "score": 50,
        "payload": {
            "layer": "wikidata",
            "aliases": [
                "Ehlers-Danlos syndrome, cardiac valvular type",
                "Ehlers-Danlos syndrome, musculocontractural type",
                "Ehlers-Danlos syndrome, fibronectinemic type",
                "Bethlem myopathy 2",
                "type I Ehlers-Danlos syndrome",
                "type III Ehlers-Danlos syndrome",
                "type V Ehlers-Danlos syndrome",
                "Ehlers-Danlos syndrome, periodontitis type",
                "Ehlers-Danlos syndrome, dermatosparaxis type",
                "Ehlers-Danlos syndrome, spondylocheirodysplastic type",
                "Ehlers-Danlos syndrome, kyphoscoliotic and deafness type",
                "Ehlers-Danlos syndrome, vascular-like type",
                "brittle cornea syndrome 2",
                "brittle cornea syndrome",
                "Ehlers-Danlos syndrome cardiac valvular type",
                "Ehlers-Danlos syndrome musculocontractural type 1",
                "Ehlers-Danlos syndrome kyphoscoliotic type 1",
                "Ehlers-Danlos syndrome kyphoscoliotic type 2",
                "Ehlers-Danlos syndrome classic-like 1",
                "Ehlers-Danlos syndrome classic-like 2",
                "Ehlers-Danlos syndrome classic type 2",
                "Ehlers-Danlos syndrome arthrochalasia type 1",
                "Ehlers-Danlos syndrome arthrochalasia type 2",
                "Ehlers-Danlos syndrome dermatosparaxis type",
                "Ehlers-Danlos syndrome musculocontractural type 2",
                "Ehlers-Danlos syndrome progeroid type",
                "autosomal recessive type IV Ehlers-Danlos syndrome",
                "Ehlers-Danlos syndrome, arthrochalasis type",
                "autosomal dominant type IV Ehlers-Danlos syndrome",
                "Ehlers-Danlos syndrome, autosomal dominant, type unspecified",
                "Ehlers-Danlos syndrome, Beasley-Cohen type",
                "Ehlers-Danlos syndrome type 2",
                "Ehlers-Danlos syndrome type 7A",
                "Ehlers-Danlos syndrome type 7B"
            ],
            "aliasCount": 34,
            "merged": 34,
            "knownIn": 50,
            "facets": null,
            "markers": [],
            "lexicalClass": "",
            "senseRank": null,
            "alsoRegisteredAs": null,
            "source": {
                "dataset": "wikidata",
                "item": "Q1141499",
                "url": "https://www.wikidata.org/wiki/Q1141499",
                "license": "CC0 1.0"
            }
        },
        "research": {
            "vercy": "1.0-draft",
            "publication": {
                "status": "research-draft",
                "adjudicationStatus": "unreviewed",
                "publishableCanonical": false,
                "generatedAt": "2026-09-12T02:41:47Z",
                "providers": [
                    "Claude"
                ],
                "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify",
                "pass": 2,
                "wave": 2,
                "engine": "claude"
            },
            "metaModel": {
                "id": "THING-Q1141499",
                "registryId": "vr.tr.ehlers-danlos-syndrome",
                "name": "Ehlers-Danlos syndrome",
                "version": "0.2.0-wave.2",
                "entryKind": "thing",
                "family": "Thing Registry",
                "domain": [
                    "XCT.STA"
                ],
                "status": "research-draft"
            },
            "canonicalUrl": "https://ver.cy/models/thing/q1141499/",
            "model": {
                "registry_id": "vr.tr.ehlers-danlos-syndrome",
                "name": "Ehlers-Danlos syndrome",
                "purpose": "Let an agent explain Ehlers-Danlos syndromes and their types, relay general information on diagnosis, management and support from expert bodies, describe living with the condition, and route personal medical questions to clinicians.",
                "definition": "A group of inherited connective tissue disorders caused by defects in collagen or related proteins, characterised by joint hypermobility, stretchy or fragile skin and tissue fragility, with types classified by clinical features and genetics including classical, hypermobile, vascular, kyphoscoliotic, cardiac valvular and musculocontractural types; severity ranges from mild to life-threatening in the vascular type, and care involves diagnosis by clinical criteria and genetic testing, multidisciplinary management and genetic counselling.",
                "what_it_is_for": "Inherited connective tissue disorders.",
                "affordances": [
                    "explain types",
                    "relay diagnosis and management information",
                    "describe living with the condition",
                    "route personal questions"
                ],
                "distinguishing_features": [
                    "Genetic",
                    "Multiple types",
                    "Connective tissue fragility",
                    "Multidisciplinary care"
                ],
                "appearance": "Not physical as a category; features include hypermobile joints and stretchy skin.",
                "visual_identification": [
                    "Inherited collagen-related disorders",
                    "Hypermobility and tissue fragility",
                    "Marfan syndrome and hypermobility spectrum disorder are related but distinct"
                ],
                "physical_properties": [],
                "families_and_kinds": [
                    "classical type",
                    "hypermobile type",
                    "vascular type",
                    "kyphoscoliotic and cardiac valvular types",
                    "rare types such as musculocontractural"
                ],
                "related_models": [
                    {
                        "relation": "is a kind of",
                        "target": "collagen disease",
                        "why": "category"
                    },
                    {
                        "relation": "is related to",
                        "target": "dwarfism",
                        "why": "another genetic condition entry"
                    },
                    {
                        "relation": "is related to",
                        "target": "scar",
                        "why": "atypical scarring as a feature"
                    },
                    {
                        "relation": "is related to",
                        "target": "nurse-patient relation",
                        "why": "care relationships"
                    }
                ],
                "identifiers": [],
                "standards_and_regulation": [
                    "International classification of Ehlers-Danlos syndromes",
                    "Clinical guidelines for management",
                    "Genetic testing and counselling standards"
                ],
                "failure_modes_and_hazards": [
                    "Agents giving personal diagnostic advice",
                    "Delayed or missed diagnosis",
                    "Confusing types with different risks"
                ],
                "in_scope": [],
                "out_of_scope": [],
                "characteristics": []
            },
            "sources": [],
            "structure": {
                "bundles": [
                    {
                        "id": "understand",
                        "name": "Understand",
                        "description": "What the syndromes are.",
                        "rationale": "General information.",
                        "layers": [
                            {
                                "id": "types",
                                "name": "Types",
                                "description": "Types.",
                                "findings": [
                                    {
                                        "id": "types-finding",
                                        "name": "Types",
                                        "description": "Types.",
                                        "questions": [
                                            {
                                                "text": "What are the types of Ehlers-Danlos syndrome, and how do their features and genetics differ?",
                                                "kind": "definition"
                                            },
                                            {
                                                "text": "Is the user asking about their own diagnosis, which needs a clinician?",
                                                "kind": "boundary"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "cause",
                                "name": "Cause",
                                "description": "Causes.",
                                "findings": [
                                    {
                                        "id": "cause-finding",
                                        "name": "Cause",
                                        "description": "Causes.",
                                        "questions": [
                                            {
                                                "text": "How do collagen and related protein defects cause the features, and how is the condition inherited?",
                                                "kind": "provenance"
                                            },
                                            {
                                                "text": "Which entry fits genetics?",
                                                "kind": "action"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "diagnose",
                        "name": "Diagnose",
                        "description": "Diagnosis and management.",
                        "rationale": "Guidelines.",
                        "layers": [
                            {
                                "id": "diagnosis",
                                "name": "Diagnosis",
                                "description": "Diagnosis.",
                                "findings": [
                                    {
                                        "id": "diagnosis-finding",
                                        "name": "Diagnosis",
                                        "description": "Diagnosis.",
                                        "questions": [
                                            {
                                                "text": "How are the syndromes diagnosed by clinical criteria and genetic testing, according to expert bodies?",
                                                "kind": "provenance"
                                            },
                                            {
                                                "text": "Which entry fits genetic testing?",
                                                "kind": "action"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "management",
                                "name": "Management",
                                "description": "Management.",
                                "findings": [
                                    {
                                        "id": "management-finding",
                                        "name": "Management",
                                        "description": "Management.",
                                        "questions": [
                                            {
                                                "text": "How are the syndromes managed across specialties, and what precautions apply to the vascular type, in general terms?",
                                                "kind": "provenance"
                                            },
                                            {
                                                "text": "Is urgent care needed now, for example for suspected vascular rupture?",
                                                "kind": "boundary"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "live",
                        "name": "Live",
                        "description": "Living with the condition.",
                        "rationale": "Support.",
                        "layers": [
                            {
                                "id": "daily",
                                "name": "Daily",
                                "description": "Daily life.",
                                "findings": [
                                    {
                                        "id": "daily-finding",
                                        "name": "Daily",
                                        "description": "Daily.",
                                        "questions": [
                                            {
                                                "text": "How do people manage pain, fatigue, mobility and daily activities, according to patient organisations and clinicians?",
                                                "kind": "provenance"
                                            },
                                            {
                                                "text": "Which entry fits chronic pain?",
                                                "kind": "action"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "support",
                                "name": "Support",
                                "description": "Support and rights.",
                                "findings": [
                                    {
                                        "id": "support-finding",
                                        "name": "Support",
                                        "description": "Support.",
                                        "questions": [
                                            {
                                                "text": "What support organisations and accommodations exist?",
                                                "kind": "provenance"
                                            },
                                            {
                                                "text": "Which entry fits disability rights?",
                                                "kind": "action"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "learn",
                        "name": "Learn",
                        "description": "Research and history.",
                        "rationale": "Education.",
                        "layers": [
                            {
                                "id": "research",
                                "name": "Research",
                                "description": "Research.",
                                "findings": [
                                    {
                                        "id": "research-finding",
                                        "name": "Research",
                                        "description": "Research.",
                                        "questions": [
                                            {
                                                "text": "What research is under way on genetics and treatment, and which findings are uncertain?",
                                                "kind": "provenance"
                                            },
                                            {
                                                "text": "Which references are standard?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "history",
                                "name": "History",
                                "description": "History.",
                                "findings": [
                                    {
                                        "id": "history-finding",
                                        "name": "History",
                                        "description": "History.",
                                        "questions": [
                                            {
                                                "text": "How were the syndromes described and classified historically?",
                                                "kind": "provenance"
                                            },
                                            {
                                                "text": "Which misconceptions arise?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    }
                ]
            },
            "openQuestions": [
                "Should each type be a separate entry?",
                "How should expert bodies be linked?",
                "How should patient organisations be linked?"
            ],
            "statistics": {
                "bundles": 4,
                "layers": 8,
                "findings": 8,
                "questions": 16
            }
        },
        "draft": {
            "generator": "vr.draft.v3",
            "status": "draft-generated",
            "researched": false,
            "archetype": "disease or condition",
            "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.",
            "facetsInferred": true,
            "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.",
            "purpose": "Give an agent a durable, checkable way to recognise a Ehlers-Danlos syndrome, record what state it is in, and decide what may be done with it.",
            "whatItIs": "Let an agent explain Ehlers-Danlos syndromes and their types, relay general information on diagnosis, management and support from expert bodies, describe living with the condition, and route personal medical questions to clinicians.",
            "characteristics": {
                "substance": "abstract",
                "origin": "conceptual",
                "agency": "inert"
            },
            "whatYouCanDoWithIt": [
                "observed and measured"
            ],
            "distinguishingFeatures": [
                "Names folded into this entry, which a task may need to split apart again: Ehlers-Danlos syndrome, cardiac valvular type, Ehlers-Danlos syndrome, musculocontractural type, Ehlers-Danlos syndrome, fibronectinemic type, Bethlem myopathy 2, type I Ehlers-Danlos syndrome, type III Ehlers-Danlos syndrome, type V Ehlers-Danlos syndrome, Ehlers-Danlos syndrome, periodontitis type, Ehlers-Danlos syndrome, dermatosparaxis type, Ehlers-Danlos syndrome, spondylocheirodysplastic type, Ehlers-Danlos syndrome, kyphoscoliotic and deafness type, Ehlers-Danlos syndrome, vascular-like type.",
                "34 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.",
                "Described in 50 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is."
            ],
            "openQuestionsForResearch": [
                "Which of the bundles below does a real task actually need, and which are ceremony?",
                "What does this thing have that the facets do not capture at all?",
                "Which neighbouring kind is most often confused with a Ehlers-Danlos syndrome, and on what evidence are they told apart?"
            ],
            "whatItIsMadeOf": "an abstraction with no physical instance",
            "physicalCharacter": [
                "Does nothing on its own; everything it does, something else did to it.",
                "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing."
            ],
            "whatCanBeDoneWithIt": [
                "observe it, measure it, record its state"
            ],
            "howItIsRecognised": [
                "Recognised by criteria applied to signs and findings, not by appearance. Two conditions can look identical and be distinguished only by test."
            ],
            "relatedModels": [
                {
                    "relation": "covers",
                    "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.",
                    "targets": [
                        "Ehlers-Danlos syndrome, cardiac valvular type",
                        "Ehlers-Danlos syndrome, musculocontractural type",
                        "Ehlers-Danlos syndrome, fibronectinemic type",
                        "Bethlem myopathy 2",
                        "type I Ehlers-Danlos syndrome",
                        "type III Ehlers-Danlos syndrome",
                        "type V Ehlers-Danlos syndrome",
                        "Ehlers-Danlos syndrome, periodontitis type",
                        "Ehlers-Danlos syndrome, dermatosparaxis type",
                        "Ehlers-Danlos syndrome, spondylocheirodysplastic type",
                        "Ehlers-Danlos syndrome, kyphoscoliotic and deafness type",
                        "Ehlers-Danlos syndrome, vascular-like type"
                    ]
                }
            ],
            "standing": "Described in 50 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 34 finer distinctions are held inside this entry as names rather than as separate models.",
            "structure": {
                "bundles": [
                    {
                        "id": "identity-and-classification",
                        "name": "Identity, naming and classification",
                        "description": "How an agent tells one Ehlers-Danlos syndrome from another, and a Ehlers-Danlos syndrome from things that resemble it.",
                        "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.",
                        "layers": [
                            {
                                "id": "naming-and-identifiers",
                                "name": "Names and identifiers",
                                "description": "The names this thing goes by and the identifiers that survive translation and time.",
                                "findings": [
                                    {
                                        "id": "preferred-name-and-aliases",
                                        "name": "Preferred name, aliases and local names",
                                        "description": "Which name to use, which names mean the same thing, and which merely sound similar.",
                                        "questions": [
                                            {
                                                "id": "preferred-name-and-aliases-q01",
                                                "text": "What identifies and describes the name of a Ehlers-Danlos syndrome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "preferred-name-and-aliases-q02",
                                                "text": "Who or what asserted this about the name of a Ehlers-Danlos syndrome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "preferred-name-and-aliases-q03",
                                                "text": "What may an agent decide or do once the name of a Ehlers-Danlos syndrome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    },
                                    {
                                        "id": "stable-identifiers",
                                        "name": "Stable identifiers and external keys",
                                        "description": "Identifiers that keep pointing at this kind of thing across systems and languages.",
                                        "questions": [
                                            {
                                                "id": "stable-identifiers-q01",
                                                "text": "What identifies and describes an identifier for a Ehlers-Danlos syndrome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "stable-identifiers-q02",
                                                "text": "Who or what asserted this about an identifier for a Ehlers-Danlos syndrome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "stable-identifiers-q03",
                                                "text": "What may an agent decide or do once an identifier for a Ehlers-Danlos syndrome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "classification-and-granularity",
                                "name": "Classification and granularity",
                                "description": "Where a Ehlers-Danlos syndrome sits among kinds, and how finely a task needs to cut it.",
                                "findings": [
                                    {
                                        "id": "kind-and-parents",
                                        "name": "Kind, parents and neighbouring kinds",
                                        "description": "The classes this thing belongs to and the ones it is next to.",
                                        "questions": [
                                            {
                                                "id": "kind-and-parents-q01",
                                                "text": "What identifies and describes the kind of a Ehlers-Danlos syndrome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "kind-and-parents-q02",
                                                "text": "Who or what asserted this about the kind of a Ehlers-Danlos syndrome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "kind-and-parents-q03",
                                                "text": "What may an agent decide or do once the kind of a Ehlers-Danlos syndrome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    },
                                    {
                                        "id": "distinguishing-features",
                                        "name": "Distinguishing features",
                                        "description": "What separates a Ehlers-Danlos syndrome from the things most often confused with it.",
                                        "questions": [
                                            {
                                                "id": "distinguishing-features-q01",
                                                "text": "What identifies and describes what distinguishes a Ehlers-Danlos syndrome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "distinguishing-features-q02",
                                                "text": "Who or what asserted this about what distinguishes a Ehlers-Danlos syndrome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "distinguishing-features-q03",
                                                "text": "What may an agent decide or do once what distinguishes a Ehlers-Danlos syndrome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "state-and-lifecycle",
                        "name": "State and lifecycle",
                        "description": "The states a Ehlers-Danlos syndrome passes through and the events that move it between them.",
                        "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.",
                        "layers": [
                            {
                                "id": "lifecycle-stages",
                                "name": "Lifecycle stages",
                                "description": "From coming into existence to ceasing to be one of these.",
                                "findings": [
                                    {
                                        "id": "stages-and-transitions",
                                        "name": "Stages and transitions",
                                        "description": "The stages worth naming and what moves a Ehlers-Danlos syndrome between them.",
                                        "questions": [
                                            {
                                                "id": "stages-and-transitions-q01",
                                                "text": "What identifies and describes the lifecycle of a Ehlers-Danlos syndrome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "stages-and-transitions-q02",
                                                "text": "Who or what asserted this about the lifecycle of a Ehlers-Danlos syndrome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "stages-and-transitions-q03",
                                                "text": "What may an agent decide or do once the lifecycle of a Ehlers-Danlos syndrome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "observations-and-status",
                                "name": "Observations and current status",
                                "description": "What is observed about a Ehlers-Danlos syndrome, how often and by whom.",
                                "findings": [
                                    {
                                        "id": "observation-record",
                                        "name": "Observation record",
                                        "description": "How an observation of a Ehlers-Danlos syndrome is recorded so that it can be superseded rather than overwritten.",
                                        "questions": [
                                            {
                                                "id": "observation-record-q01",
                                                "text": "What identifies and describes an observation of a Ehlers-Danlos syndrome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "observation-record-q02",
                                                "text": "Who or what asserted this about an observation of a Ehlers-Danlos syndrome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "observation-record-q03",
                                                "text": "What may an agent decide or do once an observation of a Ehlers-Danlos syndrome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "diagnosis-and-criteria",
                        "name": "Diagnosis, criteria and coding",
                        "description": "What makes a case of Ehlers-Danlos syndrome a case, and under which revision.",
                        "rationale": "Criteria change between revisions, so a diagnosis without its coding revision cannot be compared with a later one.",
                        "layers": [
                            {
                                "id": "criteria",
                                "name": "Diagnostic criteria",
                                "description": "The criteria in force and who issues them.",
                                "findings": [
                                    {
                                        "id": "criteria-record",
                                        "name": "Criteria, issuer and revision",
                                        "description": "What must be true for a diagnosis, according to whom.",
                                        "questions": [
                                            {
                                                "id": "criteria-record-q01",
                                                "text": "What criteria define Ehlers-Danlos syndrome, issued by which body, in which revision?",
                                                "kind": "definition"
                                            },
                                            {
                                                "id": "criteria-record-q02",
                                                "text": "What changed between revisions that would reclassify existing cases?",
                                                "kind": "boundary"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "coding",
                                "name": "Coding and terminology",
                                "description": "The codes used to record it and their mapping.",
                                "findings": [
                                    {
                                        "id": "coding-record",
                                        "name": "Codes and mappings",
                                        "description": "Which classification codes apply and how they map.",
                                        "questions": [
                                            {
                                                "id": "coding-record-q01",
                                                "text": "Which classification and terminology codes cover Ehlers-Danlos syndrome, and how do they map to each other?",
                                                "kind": "definition"
                                            },
                                            {
                                                "id": "coding-record-q02",
                                                "text": "What is lost when a case is mapped from one scheme to another?",
                                                "kind": "boundary"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "course-and-population",
                        "name": "Course, population and care",
                        "description": "How Ehlers-Danlos syndrome develops, whom it affects, and what is done about it.",
                        "rationale": "The condition, the diagnosis and the episode of care are three different things, and an agent must not merge them.",
                        "layers": [
                            {
                                "id": "course",
                                "name": "Course and stages",
                                "description": "Onset, progression, remission and outcome.",
                                "findings": [
                                    {
                                        "id": "course-record",
                                        "name": "Stages and transitions",
                                        "description": "The stages recorded and what moves a case between them.",
                                        "questions": [
                                            {
                                                "id": "course-record-q01",
                                                "text": "What course does Ehlers-Danlos syndrome typically take, and what marks each stage?",
                                                "kind": "definition"
                                            },
                                            {
                                                "id": "course-record-q02",
                                                "text": "What separates the condition itself from an episode of care for it?",
                                                "kind": "boundary"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "population",
                                "name": "Affected populations",
                                "description": "Who is affected, how often, and on what evidence.",
                                "findings": [
                                    {
                                        "id": "epidemiology",
                                        "name": "Prevalence and its basis",
                                        "description": "Rates with their population, period and source.",
                                        "questions": [
                                            {
                                                "id": "epidemiology-q01",
                                                "text": "What prevalence or incidence is reported for Ehlers-Danlos syndrome, in which population and period?",
                                                "kind": "measurement"
                                            },
                                            {
                                                "id": "epidemiology-q02",
                                                "text": "What may an agent not conclude about an individual from a population rate?",
                                                "kind": "action"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "provenance-and-evidence",
                        "name": "Provenance, evidence and time",
                        "description": "Where every claim about a Ehlers-Danlos syndrome came from and when it held.",
                        "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.",
                        "layers": [
                            {
                                "id": "source-and-authority",
                                "name": "Source and authority",
                                "description": "Who said it, on what evidence, and how strongly.",
                                "findings": [
                                    {
                                        "id": "claim-provenance",
                                        "name": "Claim provenance and confidence",
                                        "description": "The authority behind each claim about a Ehlers-Danlos syndrome and how confident it is.",
                                        "questions": [
                                            {
                                                "id": "claim-provenance-q01",
                                                "text": "What identifies and describes a claim about a Ehlers-Danlos syndrome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "claim-provenance-q02",
                                                "text": "Who or what asserted this about a claim about a Ehlers-Danlos syndrome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "claim-provenance-q03",
                                                "text": "What may an agent decide or do once a claim about a Ehlers-Danlos syndrome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "time-and-versions",
                                "name": "Time, versions and supersession",
                                "description": "When a claim was true, when it was learnt, and what replaced it.",
                                "findings": [
                                    {
                                        "id": "validity-and-supersession",
                                        "name": "Validity period and supersession",
                                        "description": "How an old claim about a Ehlers-Danlos syndrome is retired without being erased.",
                                        "questions": [
                                            {
                                                "id": "validity-and-supersession-q01",
                                                "text": "What identifies and describes the validity of a claim about a Ehlers-Danlos syndrome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "validity-and-supersession-q02",
                                                "text": "Who or what asserted this about the validity of a claim about a Ehlers-Danlos syndrome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "validity-and-supersession-q03",
                                                "text": "What may an agent decide or do once the validity of a claim about a Ehlers-Danlos syndrome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    }
                ]
            },
            "statistics": {
                "bundles": 5,
                "layers": 10,
                "findings": 12,
                "questions": 32
            }
        }
    }
}