uterine cancer
Let an agent explain uterine cancer in general terms, relay types, risk factors, symptoms, diagnosis and treatment from oncology and gynaecology sources, advise prompt medical assessment of postmenopausal or abnormal bleeding, point to patient support organisations, and distinguish uterine cancer from cervical cancer, ovarian cancer, fibroids and endometrial hyperplasia, without diagnosing individuals.
Research draft, second pass
A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.
written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify
Researched by: Claude
Purpose and description
Let an agent explain uterine cancer in general terms, relay types, risk factors, symptoms, diagnosis and treatment from oncology and gynaecology sources, advise prompt medical assessment of postmenopausal or abnormal bleeding, point to patient support organisations, and distinguish uterine cancer from cervical cancer, ovarian cancer, fibroids and endometrial hyperplasia, without diagnosing individuals.
Cancer arising in the uterus, most commonly endometrial carcinoma from the uterine lining, including endometrioid carcinoma and less common aggressive types such as uterine serous carcinoma, papillary, undifferentiated and neuroendocrine carcinomas of the corpus uteri, and rarer uterine sarcomas and tumours such as perivascular epithelioid cell tumour; the most common warning sign is abnormal vaginal bleeding, especially after menopause, which should always be checked by a doctor. Cervical cancer is usually classified separately.
What it is for: Not applicable; a disease group.
It can be explain in general terms; relay types and treatments; route symptoms to medical care; distinguish related conditions.
Distinguishing features
Often detected early by bleeding
Linked to obesity and oestrogen exposure
Molecular classification
Aggressive rare subtypes
What it looks like
Not a visible object; diagnosed by ultrasound, biopsy and pathology.
Physical character
most common type: endometrial carcinoma note
main warning sign: postmenopausal bleeding note
staging system: FIGO note - updated 2023
molecular classes: POLE, MMRd, p53abn, NSMP list
How it is recognised
Cancer of the uterine body
Uterine serous carcinoma, PEComa of the uterus, papillary, undifferentiated and neuroendocrine carcinomas of the corpus uteri
Cervical cancer arises in the cervix; ovarian cancer in the ovaries; fibroids are benign; hyperplasia is a precursor condition
Related models
is a kind of - in registry terms
includes -
is linked to - in some cases
is contrasted with -
In practice
Families and kinds
endometrioid carcinoma
serous and clear cell carcinomas
undifferentiated and neuroendocrine carcinomas
carcinosarcoma
uterine sarcomas and PEComa
Standards and regulation
FIGO staging
ESGO-ESTRO-ESP and NCCN guidelines
Failure modes and hazards
Ignoring postmenopausal bleeding
Diagnosing individuals remotely
Confusing uterine and cervical cancer
Also called
Where this came from
wikidata · CC0 1.0
Drafted structure
Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.
Understand What uterine cancer is.
Attribution.
Definition
Definition.
Definition
Definition.
- What is uterine cancer, and how does it differ from cervical and ovarian cancer, fibroids and hyperplasia? definition
- Is there bleeding after menopause or unusual bleeding, which should be checked promptly by a doctor, or heavy bleeding with dizziness needing urgent care? boundary
Types
Named types.
Types
Types.
- What are uterine serous carcinoma, PEComa and papillary, undifferentiated and neuroendocrine carcinomas of the corpus uteri? definition
- Which entry fits the specific type? action
Medical Risk and diagnosis.
Attribution.
Risk
Risk factors.
Risk
Risk.
- What risk factors do sources describe, including obesity, oestrogen exposure and Lynch syndrome? provenance
- Which references are standard? provenance
Diagnosis
Diagnosis.
Diagnosis
Diagnosis.
- How is uterine cancer diagnosed and staged? provenance
- Which sources are cited? provenance
Treatment Treatment.
Attribution.
Surgery
Surgery and therapy.
Surgery
Surgery.
- How is uterine cancer treated with surgery, radiotherapy, chemotherapy and immunotherapy, in general terms? provenance
- Which entry fits hysterectomy? action
Molecular
Molecular classes.
Molecular
Molecular.
- How does molecular classification guide treatment? provenance
- Which entry fits mismatch repair deficiency? action
Context Support.
Context.
Support
Support.
Support
Support.
- Which organisations support people with womb cancer? provenance
- Which entry fits The Eve Appeal? action
Trends
Trends.
Trends
Trends.
- How are incidence trends changing, checked against current sources? provenance
- Which entry fits cancer epidemiology? action
What the second pass must settle
- Should the named histotypes be separate entries?
- How should gynaecological oncology guidelines be linked?
- How should molecular classification updates be kept current?