neoplasm
Let an agent explain neoplasms and their classification in general terms from pathology and clinical sources, distinguish benign from malignant and neoplasms from other swellings, relay diagnosis and management principles, and route personal questions to clinicians.
Research draft, second pass
A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.
written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify
Researched by: Claude
Purpose and description
Let an agent explain neoplasms and their classification in general terms from pathology and clinical sources, distinguish benign from malignant and neoplasms from other swellings, relay diagnosis and management principles, and route personal questions to clinicians.
An abnormal mass of tissue arising from uncontrolled growth of cells that persists after the stimulus that caused it has ceased, also called a tumour, which may be benign, remaining localised, or malignant, invading tissue and spreading as cancer, with intermediate categories such as in situ and uncertain behaviour; neoplasms are classified by tissue of origin and behaviour in systems such as ICD-O and are diagnosed by imaging and histopathology.
What it is for: Not applicable; an abnormal tissue growth.
It can be explain the concept and classification; distinguish benign and malignant; relay diagnosis principles; route personal questions.
Distinguishing features
Autonomous growth
Benign or malignant behaviour
Tissue-of-origin classification
Histopathological diagnosis
What it looks like
A mass or growth, visible or detected by imaging and microscopy.
Physical character
new cancer cases: about 20 million per year worldwide - GLOBOCAN 2022
How it is recognised
Abnormal persistent cell growth
Benign, malignant, in situ, uncertain behaviour
Hyperplasia and inflammation cause swelling without neoplasia; cysts are fluid-filled
Related models
is a kind of - in registry terms
includes - as malignant neoplasm
is classified by - the oncology classification
is diagnosed by - and imaging
In practice
Families and kinds
benign neoplasms such as adenomas and lipomas
malignant neoplasms: carcinomas, sarcomas, leukaemias, lymphomas
in situ neoplasms
neoplasms of uncertain or unknown behaviour
neoplasms by organ system
Identifiers
ICD-11 chapter 2 neoplasms
ICD-O-3 morphology codes
Standards and regulation
WHO classification of tumours
Cancer registration standards
Clinical guidelines by tumour type
Failure modes and hazards
Delayed diagnosis
Agents giving personal medical advice
Confusing tumour with cancer
Stigma and fear
Where this came from
wikidata · CC0 1.0
Drafted structure
Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.
Understand What a neoplasm is.
Clinical.
Definition
Definition and behaviour.
Definition
Definition.
- What is a neoplasm, and how do benign, malignant and in situ neoplasms differ? definition
- Is the growth a neoplasm or another swelling, and is the user asking about their own lump, which needs a clinician? boundary
Classification
Classification.
Classification
Classification.
- How are neoplasms classified by tissue of origin and behaviour in WHO and ICD-O systems? definition
- Which entry fits the specific neoplasm type? action
Biology Biology.
Science.
Mechanisms
Mechanisms.
Mechanisms
Mechanisms.
- How do neoplasms arise through mutations and the hallmarks of cancer, as research describes? provenance
- Which entry fits carcinogenesis? action
Behaviour
Growth and spread.
Behaviour
Behaviour.
- How do neoplasms grow, invade and metastasise? provenance
- Which references are standard? provenance
Care Diagnosis and management.
Clinical.
Diagnosis
Diagnosis.
Diagnosis
Diagnosis.
- How are neoplasms detected, biopsied and graded, in general terms? provenance
- Is the user asking about their own results, which need their clinician? boundary
Management
Management.
Management
Management.
- How are benign and malignant neoplasms managed, in general terms? provenance
- Which entry fits oncology? action
Context Epidemiology and history.
Context.
Epidemiology
Epidemiology.
Epidemiology
Epidemiology.
- How common are neoplasms, and how are they registered, with sources? measurement
- Which sources are cited? provenance
History
History.
History
History.
- How has the understanding of tumours developed from ancient medicine to molecular oncology? provenance
- Which entry fits the history of cancer? action
What the second pass must settle
- Should cancer be the primary linked entry?
- How should classification systems be linked?
- How should uncertain-behaviour categories be recorded?