cytokinesis
Let an agent explain cytokinesis and its mechanisms across organisms, relay the contractile ring, cell plate, FtsZ and Cdv systems from cell biology references, describe regulation and errors, and distinguish cytokinesis from mitosis and karyokinesis.
Research draft, second pass
A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.
written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify
Researched by: Claude
Purpose and description
Let an agent explain cytokinesis and its mechanisms across organisms, relay the contractile ring, cell plate, FtsZ and Cdv systems from cell biology references, describe regulation and errors, and distinguish cytokinesis from mitosis and karyokinesis.
The final stage of cell division in which the cytoplasm of a parent cell divides into two daughter cells after nuclear division, carried out in animal cells by a contractile ring of actin and myosin that pinches the cell, in plant cells by the formation of a cell plate from vesicles, in bacteria by the FtsZ-dependent Z ring, and in many archaea by the Cdv system related to the ESCRT machinery; cytokinesis errors produce multinucleate cells and contribute to cancer.
What it is for: Not applicable; a cell cycle process.
It can be explain mechanisms; relay systems across organisms; describe regulation and errors; distinguish from mitosis.
Distinguishing features
Cytoplasmic partition
Contractile ring or cell plate
Distinct bacterial and archaeal systems
Coupled to nuclear division
What it looks like
Not a visible object; a cell pinching or partitioning into two.
Physical character
animal cytokinesis duration: about 10-30 minutes - typical
key animal proteins: actin, myosin II, RhoA, anillin list
How it is recognised
Division of the cytoplasm
Cytoskeleton-dependent cytokinesis, cell plate formation, FtsZ-dependent and Cdv-dependent cytokinesis
Mitosis and meiosis divide the nucleus; binary fission is the whole bacterial division
Related models
is a kind of - in registry terms
follows - in eukaryotic cells
uses - and myosin in the contractile ring
uses - in bacteria
In practice
Families and kinds
cytoskeleton-dependent cytokinesis by contractile ring in animals and fungi
cytokinesis by cell plate formation in plants
FtsZ-dependent cytokinesis in bacteria and chloroplasts
Cdv-dependent cytokinesis in archaea
asymmetric and polar body cytokinesis
cytokinesis failure and polyploidy
Identifiers
GO GO:0000910 cytokinesis
MeSH D048749 cytokinesis
Standards and regulation
No regulation; Gene Ontology and cell biology definitions
Failure modes and hazards
Confusing cytokinesis with mitosis
Cytokinesis failure causing tetraploidy and cancer
Overgeneralising animal mechanisms to plants and prokaryotes
Also called
Where this came from
wikidata · CC0 1.0
Also registered as vr.tr.cytokinesis
Drafted structure
Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.
Understand What cytokinesis is.
Science.
Definition
Definition.
Definition
Definition.
- What is cytokinesis, and how does it relate to mitosis and karyokinesis? definition
- Is the question about cytokinesis, nuclear division or whole-cell fission? boundary
Mechanisms
Mechanisms across life.
Mechanisms
Mechanisms.
- How do the contractile ring, the plant cell plate, the bacterial FtsZ ring and the archaeal Cdv system divide cells? definition
- Which entry fits the specific mechanism? action
Regulation Regulation.
Science.
Control
Control.
Control
Control.
- How do the spindle, RhoA signalling and checkpoints position and time cytokinesis? provenance
- Which references are standard? provenance
Asymmetric
Asymmetric division.
Asymmetric
Asymmetric.
- How does asymmetric cytokinesis produce different daughter cells in development? provenance
- Which entry fits asymmetric cell division? action
Medicine Errors and disease.
Clinical.
Failure
Cytokinesis failure.
Failure
Failure.
- What happens when cytokinesis fails, and how does that relate to cancer? provenance
- Which sources are cited? provenance
Targets
Drug targets.
Targets
Targets.
- How are cytokinesis proteins and FtsZ targeted by anticancer and antibacterial research? provenance
- Which entry fits FtsZ? action
Context Evolution and history.
Context.
Evolution
Evolution.
Evolution
Evolution.
- How did cytokinesis mechanisms evolve, and what does the Cdv-ESCRT link suggest about eukaryote origins? provenance
- Which entry fits eukaryogenesis? action
History
History.
History
History.
- How was cytokinesis first observed and its mechanisms discovered? provenance
- Which entry fits the history of cell biology? action
What the second pass must settle
- Should the contractile ring and cell plate be separate entries?
- How should cell biology references be linked?
- The registry entry has merged aliases naming mechanisms; should they be split off?