{ "model": { "rank": 4775, "code": "thing-q1472", "model_id": "vr.tr.crohn-s-disease", "name": "Crohn's disease", "purpose": "Let an agent explain Crohn disease in general terms, relay diagnosis, treatment and support information from gastroenterology bodies and patient organisations, distinguish it from ulcerative colitis and irritable bowel syndrome, and route personal questions to clinicians.", "family": "Thing Registry", "category": "Cross-cutting context", "status": "research-draft", "kind": "thing", "plane": "XCT", "domain": "XCT.STA", "industry": "", "version": "", "url": "/models/thing/q1472/", "tier": 2, "score": 72, "payload": { "layer": "wikidata", "aliases": [ "terminal ileitis", "Crohn disease of the esophagus", "ileitis", "jejunoileitis", "pouchitis", "Vulvar Crohn's disease", "pediatric Crohn's disease", "ileocolitis", "gastroduodenal Crohn's disease", "Crohn's colitis" ], "aliasCount": 10, "merged": 10, "knownIn": 72, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q1472", "url": "https://www.wikidata.org/wiki/Q1472", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-12T21:17:39Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 3, "engine": "claude" }, "metaModel": { "id": "THING-Q1472", "registryId": "vr.tr.crohn-s-disease", "name": "Crohn's disease", "version": "0.2.0-wave.3", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.STA" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q1472/", "model": { "registry_id": "vr.tr.crohn-s-disease", "name": "Crohn's disease", "purpose": "Let an agent explain Crohn disease in general terms, relay diagnosis, treatment and support information from gastroenterology bodies and patient organisations, distinguish it from ulcerative colitis and irritable bowel syndrome, and route personal questions to clinicians.", "definition": "A chronic inflammatory bowel disease that can affect any part of the digestive tract, most often the end of the small intestine and the colon, causing abdominal pain, diarrhoea, weight loss and fatigue with periods of flare and remission; its cause involves genetic, immune and environmental factors, and it is managed with anti-inflammatory and immune-modifying medicines, nutrition and sometimes surgery.", "what_it_is_for": "Not applicable; a disease.", "affordances": [ "explain the disease and its course", "distinguish it from related conditions", "relay treatment and support information", "route personal questions to clinicians" ], "distinguishing_features": [ "Any part of the digestive tract", "Patchy transmural inflammation", "Flares and remissions", "Complications such as strictures and fistulas" ], "appearance": "Not visible as an object; abdominal symptoms, weight loss and fatigue in the affected person.", "visual_identification": [ "Chronic inflammation anywhere in the digestive tract", "Patchy, transmural inflammation", "Ulcerative colitis affects only the colon; irritable bowel syndrome has no inflammation" ], "physical_properties": [ { "quantity": "prevalence", "typical_range": "about 100-300", "unit": "per 100000", "note": "in high-income countries; rising elsewhere" }, { "quantity": "onset", "typical_range": "often 15-35", "unit": "years of age", "note": "with a second peak later" } ], "families_and_kinds": [ "ileal, colonic and ileocolonic disease", "upper gastrointestinal Crohn disease", "perianal disease", "paediatric Crohn disease", "pouchitis and related conditions" ], "related_models": [ { "relation": "is a kind of", "target": "inflammatory bowel disease", "why": "the category" }, { "relation": "is confused with", "target": "ulcerative colitis", "why": "the other main inflammatory bowel disease" }, { "relation": "is confused with", "target": "irritable bowel syndrome", "why": "a functional disorder" }, { "relation": "is treated by", "target": "gastroenterology", "why": "the specialty" } ], "identifiers": [ { "scheme": "ICD-10", "value_or_pattern": "K50", "note": "" }, { "scheme": "ICD-11", "value_or_pattern": "DD70", "note": "" } ], "standards_and_regulation": [ "Clinical guidelines from gastroenterology societies", "Medicines regulation for biologics", "Disability and workplace accommodation law" ], "failure_modes_and_hazards": [ "Strictures, fistulas and abscesses", "Malnutrition and growth failure in children", "Infection risk from treatment", "Agents giving personal medical advice" ], "in_scope": [], "out_of_scope": [], "characteristics": [] }, "sources": [], "structure": { "bundles": [ { "id": "understand", "name": "Understand", "description": "What Crohn disease is.", "rationale": "General information.", "layers": [ { "id": "definition", "name": "Definition", "description": "Definition and course.", "findings": [ { "id": "definition-finding", "name": "Definition", "description": "Definition.", "questions": [ { "text": "What is Crohn disease, and how does it progress with flares and remissions?", "kind": "definition" }, { "text": "Is the user asking about their own symptoms, which needs a clinician?", "kind": "boundary" } ] } ] }, { "id": "distinguish", "name": "Distinguish", "description": "Related conditions.", "findings": [ { "id": "distinguish-finding", "name": "Distinguish", "description": "Distinguish.", "questions": [ { "text": "How is it distinguished from ulcerative colitis and irritable bowel syndrome?", "kind": "definition" }, { "text": "Which entry fits ulcerative colitis?", "kind": "action" } ] } ] } ] }, { "id": "diagnose", "name": "Diagnose", "description": "Diagnosis.", "rationale": "Clinical.", "layers": [ { "id": "tests", "name": "Tests", "description": "Investigations.", "findings": [ { "id": "tests-finding", "name": "Tests", "description": "Tests.", "questions": [ { "text": "How is Crohn disease diagnosed, in general terms from guidelines?", "kind": "provenance" }, { "text": "Which entry fits endoscopy?", "kind": "action" } ] } ] }, { "id": "causes", "name": "Causes", "description": "Causes.", "findings": [ { "id": "causes-finding", "name": "Causes", "description": "Causes.", "questions": [ { "text": "What is known about genetic, immune and environmental causes, with findings attributed?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] } ] }, { "id": "treat", "name": "Treat", "description": "Treatment and living.", "rationale": "Care.", "layers": [ { "id": "treatment", "name": "Treatment", "description": "Treatment.", "findings": [ { "id": "treatment-finding", "name": "Treatment", "description": "Treatment.", "questions": [ { "text": "What treatments do guidelines describe, from medicines to surgery?", "kind": "provenance" }, { "text": "Is the presentation free of personal treatment advice?", "kind": "boundary" } ] } ] }, { "id": "living", "name": "Living", "description": "Living with the disease.", "findings": [ { "id": "living-finding", "name": "Living", "description": "Living.", "questions": [ { "text": "What diet, support and rights information do patient organisations provide?", "kind": "provenance" }, { "text": "Which entry fits patient support?", "kind": "action" } ] } ] } ] }, { "id": "study", "name": "Study", "description": "Research and teaching.", "rationale": "Study.", "layers": [ { "id": "research", "name": "Research", "description": "Research.", "findings": [ { "id": "research-finding", "name": "Research", "description": "Research.", "questions": [ { "text": "What research and new therapies are under way, with attribution?", "kind": "provenance" }, { "text": "Which entry fits inflammatory bowel disease research?", "kind": "action" } ] } ] }, { "id": "teach", "name": "Teach", "description": "Teaching.", "findings": [ { "id": "teach-finding", "name": "Teach", "description": "Teaching.", "questions": [ { "text": "How is Crohn disease taught, and which misconceptions arise?", "kind": "provenance" }, { "text": "Which entry fits gastroenterology?", "kind": "action" } ] } ] } ] } ] }, "openQuestions": [ "Should paediatric Crohn disease be a separate entry?", "How should guidelines be linked?", "The registry entry has merged aliases for site-specific forms and pouchitis; should they be split off?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "disease or condition", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a Crohn's disease, record what state it is in, and decide what may be done with it.", "whatItIs": "Let an agent explain Crohn disease in general terms, relay diagnosis, treatment and support information from gastroenterology bodies and patient organisations, distinguish it from ulcerative colitis and irritable bowel syndrome, and route personal questions to clinicians.", "characteristics": { "substance": "abstract", "origin": "conceptual", "agency": "inert" }, "whatYouCanDoWithIt": [ "observed and measured" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: terminal ileitis, Crohn disease of the esophagus, ileitis, jejunoileitis, pouchitis, Vulvar Crohn's disease, pediatric Crohn's disease, ileocolitis, gastroduodenal Crohn's disease, Crohn's colitis.", "10 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.", "Described in 72 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a Crohn's disease, and on what evidence are they told apart?" ], "whatItIsMadeOf": "an abstraction with no physical instance", "physicalCharacter": [ "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state" ], "howItIsRecognised": [ "Recognised by criteria applied to signs and findings, not by appearance. Two conditions can look identical and be distinguished only by test." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "terminal ileitis", "Crohn disease of the esophagus", "ileitis", "jejunoileitis", "pouchitis", "Vulvar Crohn's disease", "pediatric Crohn's disease", "ileocolitis", "gastroduodenal Crohn's disease", "Crohn's colitis" ] } ], "standing": "Described in 72 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 10 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one Crohn's disease from another, and a Crohn's disease from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a Crohn's disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a Crohn's disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a Crohn's disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a Crohn's disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a Crohn's disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a Crohn's disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a Crohn's disease sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a Crohn's disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a Crohn's disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a Crohn's disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a Crohn's disease from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a Crohn's disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a Crohn's disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a Crohn's disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a Crohn's disease passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a Crohn's disease between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a Crohn's disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a Crohn's disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a Crohn's disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a Crohn's disease, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a Crohn's disease is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a Crohn's disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a Crohn's disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a Crohn's disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "diagnosis-and-criteria", "name": "Diagnosis, criteria and coding", "description": "What makes a case of Crohn's disease a case, and under which revision.", "rationale": "Criteria change between revisions, so a diagnosis without its coding revision cannot be compared with a later one.", "layers": [ { "id": "criteria", "name": "Diagnostic criteria", "description": "The criteria in force and who issues them.", "findings": [ { "id": "criteria-record", "name": "Criteria, issuer and revision", "description": "What must be true for a diagnosis, according to whom.", "questions": [ { "id": "criteria-record-q01", "text": "What criteria define Crohn's disease, issued by which body, in which revision?", "kind": "definition" }, { "id": "criteria-record-q02", "text": "What changed between revisions that would reclassify existing cases?", "kind": "boundary" } ] } ] }, { "id": "coding", "name": "Coding and terminology", "description": "The codes used to record it and their mapping.", "findings": [ { "id": "coding-record", "name": "Codes and mappings", "description": "Which classification codes apply and how they map.", "questions": [ { "id": "coding-record-q01", "text": "Which classification and terminology codes cover Crohn's disease, and how do they map to each other?", "kind": "definition" }, { "id": "coding-record-q02", "text": "What is lost when a case is mapped from one scheme to another?", "kind": "boundary" } ] } ] } ] }, { "id": "course-and-population", "name": "Course, population and care", "description": "How Crohn's disease develops, whom it affects, and what is done about it.", "rationale": "The condition, the diagnosis and the episode of care are three different things, and an agent must not merge them.", "layers": [ { "id": "course", "name": "Course and stages", "description": "Onset, progression, remission and outcome.", "findings": [ { "id": "course-record", "name": "Stages and transitions", "description": "The stages recorded and what moves a case between them.", "questions": [ { "id": "course-record-q01", "text": "What course does Crohn's disease typically take, and what marks each stage?", "kind": "definition" }, { "id": "course-record-q02", "text": "What separates the condition itself from an episode of care for it?", "kind": "boundary" } ] } ] }, { "id": "population", "name": "Affected populations", "description": "Who is affected, how often, and on what evidence.", "findings": [ { "id": "epidemiology", "name": "Prevalence and its basis", "description": "Rates with their population, period and source.", "questions": [ { "id": "epidemiology-q01", "text": "What prevalence or incidence is reported for Crohn's disease, in which population and period?", "kind": "measurement" }, { "id": "epidemiology-q02", "text": "What may an agent not conclude about an individual from a population rate?", "kind": "action" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a Crohn's disease came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a Crohn's disease and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a Crohn's disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a Crohn's disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a Crohn's disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a Crohn's disease is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a Crohn's disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a Crohn's disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a Crohn's disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 5, "layers": 10, "findings": 12, "questions": 32 } } } }