human microbiome
Let an agent explain the human microbiome, relay composition, functions and research findings from microbiology and medical sources with attribution, describe the skin and salivary communities the registry aliases name, and distinguish the microbiome from microbiota as organisms, from infections and from probiotic marketing claims, without personal medical advice.
Research draft, second pass
A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.
written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify
Researched by: Claude
Purpose and description
Let an agent explain the human microbiome, relay composition, functions and research findings from microbiology and medical sources with attribution, describe the skin and salivary communities the registry aliases name, and distinguish the microbiome from microbiota as organisms, from infections and from probiotic marketing claims, without personal medical advice.
The collection of microorganisms, including bacteria, archaea, fungi and viruses, and their genes living on and in the human body, with distinct communities in the gut, skin, mouth, respiratory tract and urogenital tract, such as the human skin flora and the salivary microbiome; the microbiome contributes to digestion, immunity and protection against pathogens, and research on its links to disease is active but many popular claims outpace the evidence.
What it is for: Not applicable; a biological community.
It can be explain composition and functions; relay research with attribution; describe body site communities; distinguish related concepts.
Distinguishing features
Body site specific
Functional roles
Individual variation
Active research
What it looks like
Not a visible object; microbial communities.
Physical character
ratio of bacterial to human cells: about 1:1 note - revised estimate 2016
Human Microbiome Project: 2007-2016 note - NIH
gut bacteria: hundreds of species per person note
How it is recognised
Microbial communities and genes of the human body
Human skin flora, salivary microbiome, gut microbiome
Microbiota are the organisms; infections are harmful invasions; probiotics are products
Related models
is a kind of - in registry terms
includes -
is studied by -
is contrasted with - marketed products
In practice
Families and kinds
gut microbiome
skin flora
oral and salivary microbiome
respiratory microbiome
vaginal microbiome
infant microbiome development
Standards and regulation
Regulation of probiotic and microbiome health claims
Faecal microbiota transplant regulations
Failure modes and hazards
Overstating microbiome health claims
Agents giving personal medical or supplement advice
Confusing correlation with causation
Also called
Where this came from
wikidata · CC0 1.0
Drafted structure
Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.
Understand What the human microbiome is.
Science.
Definition
Definition.
Definition
Definition.
- What is the human microbiome, and how does it differ from microbiota, infections and probiotic products? definition
- Is the question about science, a body site or a personal health or supplement decision needing a clinician? boundary
Sites
Body sites.
Sites
Sites.
- What characterises skin flora, the salivary microbiome and gut communities? definition
- Which entry fits the specific site? action
Science Functions and methods.
Science.
Functions
Functions.
Functions
Functions.
- How do microbes contribute to digestion, immunity and colonisation resistance? provenance
- Which references are standard? provenance
Methods
Methods.
Methods
Methods.
- How is the microbiome studied with sequencing and metagenomics? provenance
- Which sources are cited? provenance
Health Health research.
Attribution.
Disease links
Disease links.
Disease links
Disease links.
- What do studies report about microbiome links to disease, and what is established versus speculative, with findings attributed? provenance
- Is the presentation careful about evidence? boundary
Therapies
Therapies.
Therapies
Therapies.
- What is the evidence for faecal microbiota transplant and probiotics, in general terms? provenance
- Which entry fits fecal microbiota transplant? action
Context Development and history.
Context.
Development
Development.
Development
Development.
- How does the microbiome develop from birth and change with age? provenance
- Which entry fits infant gut microbiota? action
History
History.
History
History.
- How did microbiome science develop from Leeuwenhoek to metagenomics? provenance
- Which entry fits the history of microbiology? action
What the second pass must settle
- Should skin flora and salivary microbiome be separate primary entries?
- How should microbiology sources be linked?
- How should research uncertainty be presented?