{ "model": { "rank": 4451, "code": "thing-q155098", "model_id": "vr.tr.leptospirosis", "name": "leptospirosis", "purpose": "Enable an agent to recognise leptospirosis, assess the evidence and severity of a suspected episode, and identify appropriate clinical and public-health actions.", "family": "Thing Registry", "category": "Activities and processes", "status": "research-draft", "kind": "thing", "plane": "ACT", "domain": "ACT.ACT", "industry": "", "version": "", "url": "/models/thing/q155098/", "tier": 2, "score": 75, "payload": { "layer": "wikidata", "aliases": [ "Weil's disease", "canine leptospirosis", "bovine leptospirosis", "pig leptospirosis", "milker's fever", "leptospiral meningitis" ], "aliasCount": 6, "merged": 6, "knownIn": 75, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q155098", "url": "https://www.wikidata.org/wiki/Q155098", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-09T20:15:29Z", "providers": [ "Codex" ], "breadth": "recalled by Codex without web access - no source was read", "missingProviders": [], "pass": 2, "cost": { "grok": { "seconds": 24.8, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a087ce-8451-7df3-9440-21ba7e1b458c\n--------\nuser\nDescribe what is already known about one registered thing. Answer as JSON only, no prose around it.\n\nThing: leptospirosis\nSense to describe: (none recorded)\nDomain code: ACT.ACT\nAlso known as: (none)\n\n\nContext for this batch of 695 things:\n# Batch 004: 1001 re", "usd": 0, "recall": true }, "codex": { "seconds": 75.8, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a087ce-845b-70b3-b0fc-7ff9b58b6865\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: leptospirosis\nRegistry id: vr.tr.leptospirosis\nPlane / domain: ACT / ACT.ACT\nRegistry definition: (none recorded)\nNames folded into this entry: (none" } } }, "metaModel": { "id": "THING-Q155098", "registryId": "vr.tr.leptospirosis", "name": "leptospirosis", "version": "0.1.0-research.1", "entryKind": "thing", "family": "Thing Registry", "domain": [ "ACT.ACT" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q155098/", "model": { "registry_id": "vr.tr.leptospirosis", "name": "leptospirosis", "purpose": "Enable an agent to recognise leptospirosis, assess the evidence and severity of a suspected episode, and identify appropriate clinical and public-health actions.", "definition": "Leptospirosis is a zoonotic infection caused by pathogenic bacteria of the genus Leptospira, usually acquired through contact with infected animal urine or contaminated water or soil, with manifestations ranging from asymptomatic infection to life-threatening multiorgan disease.", "scope_statement": "This model owns leptospirosis as the disease concept registered as vr.tr.leptospirosis in ACT / ACT.ACT, including disease-specific evidence, course, complications and action constraints; it distinguishes the condition from its host, diagnostic assertions and episodes of care.", "in_scope": [ "Leptospira-associated disease and host-specific applicability", "Animal and environmental exposure pathways", "Time-dependent laboratory evidence and diagnostic uncertainty", "Clinical course, organ involvement and recovery", "Disease-specific management, prevention and surveillance requirements" ], "out_of_scope": [ "The patient's complete health record", "Leptospira taxonomy and organism biology beyond disease attribution", "Independent models of animal reservoirs and contaminated environments", "Drug formularies, prescribing systems and care-encounter administration", "Other febrile diseases except as differential diagnoses" ], "distinguishing_features": [ "Require evidence connecting illness to Leptospira; fever or a history of flood exposure alone cannot distinguish leptospirosis.", "Record contact with potentially urine-contaminated water, soil or animals as exposure evidence, separately from proof of infection.", "Use the combination of clinical findings, exposure history and laboratory evidence to distinguish suspected leptospirosis from alternatives such as dengue or malaria.", "Distinguish severe manifestations, including renal, hepatic or pulmonary involvement, from the broader disease concept; their absence does not exclude leptospirosis.", "Distinguish an antibody finding from a supported current episode by retaining specimen timing and the applicable interpretation criteria." ], "characteristics": [ { "name": "Host species and clinical context", "kind": "category", "unit_or_values": "Human or named animal species; clinical illness, asymptomatic infection or unresolved", "why_it_matters": "Human diagnostic and management rules must not be transferred automatically to animal hosts." }, { "name": "Exposure-to-onset interval", "kind": "measurement", "unit_or_values": "Days, with earliest and latest plausible exposure dates", "why_it_matters": "Supports assessment of temporal compatibility without inventing a precise infection date." }, { "name": "Time from symptom onset to specimen collection", "kind": "measurement", "unit_or_values": "Days; unknown onset explicitly permitted", "why_it_matters": "Leptospiral test interpretation depends on when and where material was collected." }, { "name": "Diagnostic assertion", "kind": "state", "unit_or_values": "Suspected, supported, confirmed, excluded or unresolved under a named clinical framework", "why_it_matters": "Makes certainty traceable to evidence rather than treating a disease label as proof." }, { "name": "Laboratory evidence", "kind": "relation", "unit_or_values": "Linked specimen, assay, result, laboratory, collection date and interpretation", "why_it_matters": "Preserves the basis for confirming or challenging a diagnostic assertion." }, { "name": "Organ involvement", "kind": "state", "unit_or_values": "Renal, hepatic, pulmonary, neurological and other assessed involvement; absent, present or unknown", "why_it_matters": "Supports severity assessment and escalation without reducing the disease to jaundice alone." }, { "name": "Disease course", "kind": "state", "unit_or_values": "Acute illness, deterioration, recovery, persistent manifestations, death or unresolved", "why_it_matters": "Allows longitudinal assessment without assuming every episode follows the same phases." }, { "name": "Terminology mapping", "kind": "relation", "unit_or_values": "Verified ICD-10, ICD-11 or SNOMED CT concept with edition, jurisdiction and mapping scope", "why_it_matters": "Prevents silent equivalence between codes for the disease and particular manifestations." }, { "name": "Population burden", "kind": "measurement", "unit_or_values": "Cases, incidence per defined population and period, or prevalence with denominator and year", "why_it_matters": "Separates reported disease from estimated burden and serological exposure." } ], "affordances": [ "Assemble an exposure and illness timeline to assess compatibility with leptospirosis.", "Identify missing diagnostic evidence and questions for the responsible clinician or laboratory.", "Flag documented deterioration or organ involvement for clinical review.", "Retrieve applicable management guidance using host, severity, jurisdiction and guideline version.", "Classify surveillance eligibility separately from clinical diagnostic confidence.", "Link potentially related cases for investigation while preserving uncertainty about a shared source." ] }, "sources": [], "structure": { "bundles": [ { "id": "disease-identity", "name": "Disease identity and boundaries", "description": "Establish what the leptospirosis concept covers and how assertions about it are represented.", "rationale": "An exposure, infection, clinical diagnosis and care encounter must not become interchangeable records.", "layers": [ { "id": "causal-and-host-scope", "name": "Causal and host scope", "description": "Define the disease while retaining the host context needed to interpret evidence.", "findings": [ { "id": "leptospira-associated-disease", "name": "Leptospira-associated disease", "description": "Leptospirosis affects people and animals; host-specific rules require explicit applicability. Reference: [CDC clinical overview](https://www.cdc.gov/leptospirosis/hcp/clinical-overview/index.html).", "questions": [ { "text": "What evidence attributes this illness to Leptospira, and in which host species?", "kind": "definition", "id": "leptospira-associated-disease-q01" }, { "text": "Does this assertion concern clinical disease, asymptomatic infection, exposure or a reservoir state?", "kind": "boundary", "id": "leptospira-associated-disease-q02" } ] } ] }, { "id": "terminology-and-assertions", "name": "Terminology and assertions", "description": "Keep the registered disease separate from codes, manifestations and diagnostic claims.", "findings": [ { "id": "versioned-disease-mapping", "name": "Versioned disease mapping", "description": "Require reviewed terminology mappings and explicit relationships between leptospirosis and narrower severe presentations.", "questions": [ { "text": "Which ICD-10, ICD-11 and SNOMED CT identifiers apply in the selected editions and jurisdiction?", "kind": "provenance", "id": "versioned-disease-mapping-q01" }, { "text": "Does a label such as Weil disease denote a narrower presentation rather than the entire leptospirosis concept?", "kind": "boundary", "id": "versioned-disease-mapping-q02" } ] } ] } ] }, { "id": "exposure-and-acquisition", "name": "Exposure and acquisition", "description": "Represent plausible acquisition pathways and the strength of source attribution.", "rationale": "Exposure history informs suspicion, but an environmental association does not establish where infection occurred.", "layers": [ { "id": "animal-environment-interface", "name": "Animal and environment interface", "description": "Connect relevant contact events to possible animal or environmental sources.", "findings": [ { "id": "urine-associated-exposure", "name": "Urine-associated exposure", "description": "Record potentially contaminated water, soil and animal contact, including flood-related exposures. Reference: [CDC clinical overview](https://www.cdc.gov/leptospirosis/hcp/clinical-overview/index.html).", "questions": [ { "text": "Which occupational, household or recreational contacts involved potentially contaminated water, soil or animals?", "kind": "provenance", "id": "urine-associated-exposure-q01" }, { "text": "Is contamination supported by investigation or only inferred from the setting?", "kind": "boundary", "id": "urine-associated-exposure-q02" } ] } ] }, { "id": "exposure-timing-and-linkage", "name": "Exposure timing and linkage", "description": "Preserve uncertainty in exposure dates and links between cases.", "findings": [ { "id": "plausible-acquisition-window", "name": "Plausible acquisition window", "description": "Represent candidate exposure intervals and competing source hypotheses without assigning an unsupported infection date.", "questions": [ { "text": "What interval separates each candidate exposure from symptom onset, including date uncertainty?", "kind": "measurement", "id": "plausible-acquisition-window-q01" }, { "text": "What epidemiological or laboratory evidence supports linking this episode to an animal, location or cluster?", "kind": "provenance", "id": "plausible-acquisition-window-q02" } ] } ] } ] }, { "id": "diagnostic-evidence", "name": "Diagnostic evidence", "description": "Organise clinical suspicion and laboratory interpretation around the illness timeline.", "rationale": "Symptoms are nonspecific, and test results require specimen and timing context.", "layers": [ { "id": "clinical-differentiation", "name": "Clinical differentiation", "description": "Assess compatible illness while retaining competing explanations.", "findings": [ { "id": "compatible-but-nonspecific-presentation", "name": "Compatible but nonspecific presentation", "description": "Fever, myalgia, conjunctival suffusion and jaundice may inform assessment but do not independently establish the disease. Reference: [CDC clinical overview](https://www.cdc.gov/leptospirosis/hcp/clinical-overview/index.html).", "questions": [ { "text": "Which compatible findings are documented, absent or not assessed?", "kind": "measurement", "id": "compatible-but-nonspecific-presentation-q01" }, { "text": "Which locally relevant alternatives, including dengue and malaria where applicable, remain unresolved?", "kind": "boundary", "id": "compatible-but-nonspecific-presentation-q02" } ] } ] }, { "id": "specimen-and-assay-interpretation", "name": "Specimen and assay interpretation", "description": "Interpret molecular and antibody evidence using collection timing and laboratory criteria.", "findings": [ { "id": "time-qualified-test-evidence", "name": "Time-qualified test evidence", "description": "Retain specimen type, illness day, PCR results and serological evidence; MAT is a reference serological method. Reference: [CDC Yellow Book](https://www.cdc.gov/yellow-book/hcp/travel-associated-infections-diseases/leptospirosis.html).", "questions": [ { "text": "Which specimen and assay were used, on what illness day, and with what result and laboratory interpretation?", "kind": "measurement", "id": "time-qualified-test-evidence-q01" }, { "text": "Do negative, isolated antibody or discordant results require repeat sampling or reference-laboratory review under the applicable guidance?", "kind": "action", "id": "time-qualified-test-evidence-q02" } ] } ] } ] }, { "id": "course-and-severity", "name": "Course and severity", "description": "Track disease evolution and manifestations that change urgency.", "rationale": "A positive diagnostic result does not describe current severity or subsequent recovery.", "layers": [ { "id": "organ-involvement", "name": "Organ involvement", "description": "Assess disease-associated dysfunction using observations and trends.", "findings": [ { "id": "severity-driving-manifestations", "name": "Severity-driving manifestations", "description": "Track renal, hepatic, respiratory and neurological complications with attribution confidence. Reference: [CDC clinical overview](https://www.cdc.gov/leptospirosis/hcp/clinical-overview/index.html).", "questions": [ { "text": "What do renal function, urine output, bilirubin, oxygenation and neurological observations show over time?", "kind": "measurement", "id": "severity-driving-manifestations-q01" }, { "text": "Which findings meet the applicable clinical thresholds for urgent escalation?", "kind": "action", "id": "severity-driving-manifestations-q02" } ] } ] }, { "id": "trajectory-and-outcome", "name": "Trajectory and outcome", "description": "Separate observed progression from assumed disease stages.", "findings": [ { "id": "episode-resolution-and-persistence", "name": "Episode resolution and persistence", "description": "Record deterioration, recovery and persistent manifestations without assuming discharge proves resolution.", "questions": [ { "text": "Which dated observations demonstrate improvement, recurrence of symptoms or persistent dysfunction?", "kind": "measurement", "id": "episode-resolution-and-persistence-q01" }, { "text": "What evidence distinguishes continuation of this episode from reinfection or another condition?", "kind": "boundary", "id": "episode-resolution-and-persistence-q02" } ] } ] } ] }, { "id": "management-and-prevention", "name": "Management and prevention", "description": "Connect disease evidence to supervised treatment and exposure-reduction decisions.", "rationale": "Clinical urgency, treatment suitability and preventive interventions depend on different evidence.", "layers": [ { "id": "clinical-management", "name": "Clinical management", "description": "Identify applicable treatment guidance and document the basis for action.", "findings": [ { "id": "treatment-decision-context", "name": "Treatment decision context", "description": "CDC advises early antibiotics when clinical suspicion is high; record the clinician's decision and applicable guidance. Reference: [CDC clinical overview](https://www.cdc.gov/leptospirosis/hcp/clinical-overview/index.html).", "questions": [ { "text": "Which guideline version governs treatment for this host, severity and clinical setting?", "kind": "provenance", "id": "treatment-decision-context-q01" }, { "text": "What antimicrobial and supportive-care decisions require clinician review given allergies, pregnancy, age and organ function?", "kind": "action", "id": "treatment-decision-context-q02" } ] } ] }, { "id": "exposure-reduction", "name": "Exposure reduction", "description": "Match prevention decisions to the actual exposure setting.", "findings": [ { "id": "context-specific-prevention", "name": "Context-specific prevention", "description": "Record feasible exposure controls and require separate evidence for prophylaxis or vaccination policies.", "questions": [ { "text": "Which changes to water contact, protective equipment, sanitation or animal management address the documented pathway?", "kind": "action", "id": "context-specific-prevention-q01" }, { "text": "What host-specific and jurisdiction-specific guidance supports any proposed prophylaxis or vaccination?", "kind": "provenance", "id": "context-specific-prevention-q02" } ] } ] } ] }, { "id": "surveillance-and-burden", "name": "Surveillance and burden", "description": "Support reporting, cluster assessment and interpretation of population estimates.", "rationale": "Surveillance classification and population burden must remain distinct from individual clinical diagnosis.", "layers": [ { "id": "case-definition-and-reporting", "name": "Case definition and reporting", "description": "Apply the correct surveillance framework without substituting it for clinical judgment.", "findings": [ { "id": "versioned-surveillance-classification", "name": "Versioned surveillance classification", "description": "Surveillance definitions serve case counting rather than individual diagnosis; preserve issuing body, jurisdiction and revision. Reference: [CDC 2025 case definition](https://ndc.services.cdc.gov/case-definitions/leptospirosis/).", "questions": [ { "text": "Which case-definition revision applies, and which clinical, laboratory and epidemiological criteria are satisfied?", "kind": "provenance", "id": "versioned-surveillance-classification-q01" }, { "text": "What reporting or cluster-investigation action is required by the applicable local authority?", "kind": "action", "id": "versioned-surveillance-classification-q02" } ] } ] }, { "id": "population-measurement", "name": "Population measurement", "description": "Make burden estimates comparable only when their populations and methods support comparison.", "findings": [ { "id": "qualified-burden-estimate", "name": "Qualified burden estimate", "description": "Require location, year, population, denominator, case definition and ascertainment method for every burden claim.", "questions": [ { "text": "Does this estimate measure reported cases, clinical incidence, infection prevalence, seropositivity or deaths?", "kind": "definition", "id": "qualified-burden-estimate-q01" }, { "text": "What population, period, uncertainty interval and adjustments for missed cases support the estimate?", "kind": "measurement", "id": "qualified-burden-estimate-q02" } ] } ] } ] }, { "id": "evidence-and-external-alignment", "name": "Evidence and external alignment", "description": "What the world already says about this thing, gathered so the model can be checked against it.", "rationale": "A model that cannot be lined up against existing standards, identifiers and practice cannot be adopted by anyone who already uses them.", "layers": [ { "id": "reported-evidence", "name": "Reported evidence", "description": "Findings from the breadth pass, kept separate from the structural claims.", "findings": [ { "id": "evidence-confidence-notes", "name": "Check these first", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "This is recalled knowledge, not a researched or source-verified account; confirm current guidance, surveillance definitions and terminology identifiers.", "Clinical categories overlap and are not a mutually exclusive formal classification; diagnostic thresholds depend on the assay and issuing authority.", "No population-specific incidence or prevalence estimate is supplied; any estimate needs a location, observation period and case-ascertainment method." ], "questions": [ { "id": "evidence-confidence-notes-q01", "text": "Which of these check these first hold for the sense of leptospirosis this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-kinds", "name": "Kinds and varieties", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Asymptomatic infection", "Anicteric leptospirosis", "Icteric leptospirosis, including Weil disease", "Leptospirosis with severe pulmonary haemorrhage" ], "questions": [ { "id": "evidence-kinds-q01", "text": "Which of these kinds and varieties hold for the sense of leptospirosis this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-identifiers", "name": "Identifiers and schemes", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "scheme": "WHO ICD-10", "value_or_pattern": "A27", "note": "Category for leptospirosis; subcodes distinguish specified forms. Record the ICD revision and any national modification." }, { "scheme": "SNOMED CT", "value_or_pattern": "Numeric concept identifier", "note": "The exact disease concept identifier and terminology edition require verification." } ], "questions": [ { "id": "evidence-identifiers-q01", "text": "Which of these identifiers and schemes hold for the sense of leptospirosis this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-standards-and-regulation", "name": "Standards and regulation", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "World Health Organization: Human leptospirosis: guidance for diagnosis, surveillance and control.", "US Council of State and Territorial Epidemiologists and CDC: leptospirosis surveillance case definitions; the applicable revision must accompany their use, and surveillance definitions are not individual clinical diagnostic rules." ], "questions": [ { "id": "evidence-standards-and-regulation-q01", "text": "Which of these standards and regulation hold for the sense of leptospirosis this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-real-world-use", "name": "Real-world use", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Clinical recognition of a febrile illness associated with animal, freshwater, floodwater or occupational exposure.", "Laboratory investigation using molecular detection, serology and, less commonly, culture.", "Public-health surveillance and investigation of outbreaks after flooding or shared environmental exposure.", "Occupational and recreational exposure prevention.", "Coordinated human, animal and environmental disease control." ], "questions": [ { "id": "evidence-real-world-use-q01", "text": "Which of these real-world use hold for the sense of leptospirosis this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-measurements", "name": "Typical measurements", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "quantity": "Incubation period", "typical_range": "Usually 5-14; reported range approximately 2-30", "unit": "days" } ], "questions": [ { "id": "evidence-measurements-q01", "text": "Which of these typical measurements hold for the sense of leptospirosis this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-failure-modes-and-hazards", "name": "Failure modes and hazards", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Nonspecific early symptoms can delay recognition or lead to confusion with other febrile diseases.", "Early serology can be negative; test interpretation depends on illness timing, specimen type and local epidemiology.", "Severe infection can cause acute kidney injury, jaundice, haemorrhage and circulatory failure.", "Pulmonary haemorrhage can be rapidly fatal and may occur without the classic jaundiced presentation.", "Animal reservoirs and contaminated environments can sustain exposure after individual cases are treated." ], "questions": [ { "id": "evidence-failure-modes-and-hazards-q01", "text": "Which of these failure modes and hazards hold for the sense of leptospirosis this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-regional-variation", "name": "Regional variation", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Transmission occurs worldwide but is especially associated with tropical settings, heavy rainfall, flooding and inadequate sanitation.", "Reservoir animals and circulating pathogenic species and serovars vary geographically.", "Notification requirements, laboratory access and surveillance practices differ between jurisdictions, limiting direct comparisons of reported incidence." ], "questions": [ { "id": "evidence-regional-variation-q01", "text": "Which of these regional variation hold for the sense of leptospirosis this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-neighbours", "name": "Neighbouring kinds and how to tell them apart", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "name": "Weil disease", "difference": "A severe manifestation of leptospirosis classically involving jaundice and renal impairment, often with haemorrhage; it does not encompass all leptospirosis." }, { "name": "Dengue", "difference": "A mosquito-borne viral infection; overlapping clinical features require pathogen-specific testing and exposure assessment to distinguish it from leptospirosis." }, { "name": "Hantavirus infection", "difference": "A viral infection associated with rodent exposure that can also cause renal or pulmonary disease; laboratory identification separates the causes." }, { "name": "Leptospira", "difference": "The bacterial genus contains the causative organisms; leptospirosis is the infection, not the organism, patient, diagnostic label or episode of care." } ], "questions": [ { "id": "evidence-neighbours-q01", "text": "Which of these neighbouring kinds and how to tell them apart hold for the sense of leptospirosis this model covers, and on what evidence?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Does an existing Vercy world model already own this disease concept, requiring a registry link rather than a separate publication?", "Which exact ICD-10, ICD-11 and SNOMED CT mappings are valid for the selected editions, including narrower severe presentations?", "Which host-specific clinical and laboratory criteria should be supported, and how should human and veterinary guidance be separated within this single registry entry?", "Which regional assay interpretation rules, management guidance and prevention policies are sufficiently evidenced and current?", "Which population- and year-specific burden estimates and follow-up evidence adequately distinguish clinical illness, asymptomatic infection and persistent manifestations?" ], "statistics": { "bundles": 7, "layers": 13, "findings": 21, "questions": 33 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "disease or condition", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a leptospirosis, record what state it is in, and decide what may be done with it.", "whatItIs": "Enable an agent to recognise leptospirosis, assess the evidence and severity of a suspected episode, and identify appropriate clinical and public-health actions.", "characteristics": { "substance": "activity", "origin": "conceptual", "agency": "inert" }, "whatYouCanDoWithIt": [ "observed and measured" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: Weil's disease, canine leptospirosis, bovine leptospirosis, pig leptospirosis, milker's fever, leptospiral meningitis.", "6 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.", "Described in 75 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a leptospirosis, and on what evidence are they told apart?" ], "whatItIsMadeOf": "something that happens over time", "physicalCharacter": [ "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state" ], "howItIsRecognised": [ "Recognised by criteria applied to signs and findings, not by appearance. Two conditions can look identical and be distinguished only by test." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "Weil's disease", "canine leptospirosis", "bovine leptospirosis", "pig leptospirosis", "milker's fever", "leptospiral meningitis" ] } ], "standing": "Described in 75 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 6 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one leptospirosis from another, and a leptospirosis from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a leptospirosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a leptospirosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a leptospirosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a leptospirosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a leptospirosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a leptospirosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a leptospirosis sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a leptospirosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a leptospirosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a leptospirosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a leptospirosis from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a leptospirosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a leptospirosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a leptospirosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a leptospirosis passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a leptospirosis between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a leptospirosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a leptospirosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a leptospirosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a leptospirosis, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a leptospirosis is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a leptospirosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a leptospirosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a leptospirosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "process-and-outcome", "name": "Process, inputs and outcome", "description": "How a leptospirosis proceeds, what it needs and what it leaves behind.", "rationale": "An activity is known by its steps and its results, and both have to be recordable while it is still running.", "layers": [ { "id": "steps-and-sequence", "name": "Steps and sequence", "description": "The steps of a leptospirosis, their order and what may run in parallel.", "findings": [ { "id": "steps-and-preconditions", "name": "Steps, preconditions and completion", "description": "What has to be true before each step of a leptospirosis and what marks it done.", "questions": [ { "id": "steps-and-preconditions-q01", "text": "What identifies and describes a step of a leptospirosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "steps-and-preconditions-q02", "text": "Who or what asserted this about a step of a leptospirosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "steps-and-preconditions-q03", "text": "What may an agent decide or do once a step of a leptospirosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "inputs-and-results", "name": "Inputs, resources and results", "description": "What a leptospirosis consumes and what it produces.", "findings": [ { "id": "inputs-and-outputs", "name": "Inputs, outputs and side effects", "description": "The resources a leptospirosis takes and the results it leaves, wanted or not.", "questions": [ { "id": "inputs-and-outputs-q01", "text": "What identifies and describes the inputs and results of a leptospirosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "inputs-and-outputs-q02", "text": "Who or what asserted this about the inputs and results of a leptospirosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "inputs-and-outputs-q03", "text": "What may an agent decide or do once the inputs and results of a leptospirosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "diagnosis-and-criteria", "name": "Diagnosis, criteria and coding", "description": "What makes a case of leptospirosis a case, and under which revision.", "rationale": "Criteria change between revisions, so a diagnosis without its coding revision cannot be compared with a later one.", "layers": [ { "id": "criteria", "name": "Diagnostic criteria", "description": "The criteria in force and who issues them.", "findings": [ { "id": "criteria-record", "name": "Criteria, issuer and revision", "description": "What must be true for a diagnosis, according to whom.", "questions": [ { "id": "criteria-record-q01", "text": "What criteria define leptospirosis, issued by which body, in which revision?", "kind": "definition" }, { "id": "criteria-record-q02", "text": "What changed between revisions that would reclassify existing cases?", "kind": "boundary" } ] } ] }, { "id": "coding", "name": "Coding and terminology", "description": "The codes used to record it and their mapping.", "findings": [ { "id": "coding-record", "name": "Codes and mappings", "description": "Which classification codes apply and how they map.", "questions": [ { "id": "coding-record-q01", "text": "Which classification and terminology codes cover leptospirosis, and how do they map to each other?", "kind": "definition" }, { "id": "coding-record-q02", "text": "What is lost when a case is mapped from one scheme to another?", "kind": "boundary" } ] } ] } ] }, { "id": "course-and-population", "name": "Course, population and care", "description": "How leptospirosis develops, whom it affects, and what is done about it.", "rationale": "The condition, the diagnosis and the episode of care are three different things, and an agent must not merge them.", "layers": [ { "id": "course", "name": "Course and stages", "description": "Onset, progression, remission and outcome.", "findings": [ { "id": "course-record", "name": "Stages and transitions", "description": "The stages recorded and what moves a case between them.", "questions": [ { "id": "course-record-q01", "text": "What course does leptospirosis typically take, and what marks each stage?", "kind": "definition" }, { "id": "course-record-q02", "text": "What separates the condition itself from an episode of care for it?", "kind": "boundary" } ] } ] }, { "id": "population", "name": "Affected populations", "description": "Who is affected, how often, and on what evidence.", "findings": [ { "id": "epidemiology", "name": "Prevalence and its basis", "description": "Rates with their population, period and source.", "questions": [ { "id": "epidemiology-q01", "text": "What prevalence or incidence is reported for leptospirosis, in which population and period?", "kind": "measurement" }, { "id": "epidemiology-q02", "text": "What may an agent not conclude about an individual from a population rate?", "kind": "action" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a leptospirosis came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a leptospirosis and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a leptospirosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a leptospirosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a leptospirosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a leptospirosis is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a leptospirosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a leptospirosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a leptospirosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 6, "layers": 12, "findings": 14, "questions": 38 } } } }