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Research draft

scurvy

vr.tr.scurvy · XCT.STA

Let an agent explain scurvy and its cause, relay symptoms, diagnosis, treatment and history from medical and historical sources in general terms, route people with symptoms to clinicians, and distinguish scurvy from other bleeding disorders, from rickets and from general malnutrition.

Thing Registry Cross-cutting context

Research draft, second pass

A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.

written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify

Researched by: Claude

Purpose and description

Let an agent explain scurvy and its cause, relay symptoms, diagnosis, treatment and history from medical and historical sources in general terms, route people with symptoms to clinicians, and distinguish scurvy from other bleeding disorders, from rickets and from general malnutrition.

A disease caused by deficiency of vitamin C, or ascorbic acid, producing weakness, gum disease, bleeding into skin and joints known as scorbutic purpura, poor wound healing and, in infants, neonatal or infantile scurvy with bone changes; historically the scourge of sailors and besieged populations, scurvy is now rare but occurs with restricted diets, and is cured by vitamin C, with diagnosis and treatment by clinicians.

What it is for: Not applicable; a disease.

It can be explain cause and symptoms; relay diagnosis and treatment; route to clinicians; distinguish related conditions.

Distinguishing features

Single nutrient deficiency

Collagen failure

Rapid cure

Maritime history

What it looks like

Not a visible object; bleeding gums, bruising and corkscrew hairs.

Physical character

onset: after about 1-3 months without vitamin C note

Lind s trial: 1747 year

vitamin C isolated: 1928-1932 period - Szent-Gyorgyi

daily requirement: about 75-90 mg - adults

How it is recognised

Vitamin C deficiency disease

Scorbutic purpura, neonatal scurvy

Other bleeding disorders involve clotting; rickets is vitamin D deficiency; malnutrition is broader

Related models

is a kind of - in registry terms

ascorbic acid deficiency

is caused by lack of - in the diet

vitamin C

is contrasted with - vitamin D deficiency

rickets

was studied by - in a 1747 trial

James Lind

In practice

Families and kinds

adult scurvy

infantile or neonatal scurvy

scurvy in restricted diets and eating disorders

historical scurvy at sea and in sieges

Identifiers

ICD-10 E54 ascorbic acid deficiency

MeSH D012614 Scurvy

Standards and regulation

Dietary reference intakes for vitamin C

Clinical guidelines for nutritional deficiencies

Failure modes and hazards

Missed diagnosis in modern settings

Agents giving personal medical or dietary advice

Myths about megadoses

Also called

scorbutic purpuraneonatal scurvy

Where this came from

wikidata · CC0 1.0

Drafted structure

Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.

Understand What scurvy is.

Clinical.

Definition

Definition and symptoms.

Definition

Definition.

  1. What is scurvy, what are its symptoms including scorbutic purpura, and how does it differ from other bleeding disorders and rickets? definition
  2. Is the user describing symptoms of their own, which need a clinician? boundary

Cause

Cause.

Cause

Cause.

  1. Why does vitamin C deficiency cause collagen failure and bleeding? provenance
  2. Which entry fits vitamin C? action
Care Diagnosis and treatment.

Clinical.

Diagnosis

Diagnosis.

Diagnosis

Diagnosis.

  1. How is scurvy diagnosed today, and who is at risk? provenance
  2. Which references are standard? provenance

Treatment

Treatment.

Treatment

Treatment.

  1. How is scurvy treated and prevented, in general terms? provenance
  2. Which sources are cited? provenance
History History.

Attribution.

Sea

Scurvy at sea.

Sea

Sea.

  1. How did scurvy affect voyages, and how did Lind s trial and citrus rations change naval practice? provenance
  2. Which entry fits James Lind? action

Science

Discovery of vitamin C.

Science

Science.

  1. How was vitamin C identified and its role established? provenance
  2. Which entry fits the history of vitamins? action
Context Today.

Context.

Today

Scurvy today.

Today

Today.

  1. Where does scurvy still occur, and in which groups? provenance
  2. Which entry fits malnutrition? action

Infants

Neonatal scurvy.

Infants

Infants.

  1. What is neonatal or infantile scurvy, and how is it prevented? provenance
  2. Which entry fits infant nutrition? action

What the second pass must settle

  • Should vitamin C and Lind s trial be the primary linked entries?
  • How should medical and historical sources be linked?
  • How should the neonatal form be recorded?