{ "model": { "rank": 7642, "code": "thing-q16499", "model_id": "vr.tr.hyperthyroidism", "name": "hyperthyroidism", "purpose": "Let an agent explain hyperthyroidism and its causes in general terms with attribution, describe diagnosis and treatment as documented, cover the veterinary form, and route personal questions to clinicians.", "family": "Thing Registry", "category": "Cross-cutting context", "status": "research-draft", "kind": "thing", "plane": "XCT", "domain": "XCT.STA", "industry": "", "version": "", "url": "/models/thing/q16499/", "tier": 2, "score": 54, "payload": { "layer": "wikidata", "aliases": [ "thyrotoxicosis with toxic single thyroid nodule", "Hashitoxicosis", "gestational transient thyrotoxicosis", "Thyrotoxic myopathy", "congenital hyperthyroidism", "feline hyperthyroidism", "Jod-Basedow phenomenon", "Thyrotoxic periodic paralysis", "thyrotoxicosis", "Plummer's disease", "thyrotoxic periodic paralysis, susceptibility to, 3", "neonatal thyrotoxicosis", "thyrotoxicosis from ectopic thyroid nodule" ], "aliasCount": 13, "merged": 13, "knownIn": 54, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": "vr.tr.hyperthyroidism", "source": { "dataset": "wikidata", "item": "Q16499", "url": "https://www.wikidata.org/wiki/Q16499", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-12T02:02:13Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 2, "engine": "claude" }, "metaModel": { "id": "THING-Q16499", "registryId": "vr.tr.hyperthyroidism", "name": "hyperthyroidism", "version": "0.2.0-wave.2", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.STA" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q16499/", "model": { "registry_id": "vr.tr.hyperthyroidism", "name": "hyperthyroidism", "purpose": "Let an agent explain hyperthyroidism and its causes in general terms with attribution, describe diagnosis and treatment as documented, cover the veterinary form, and route personal questions to clinicians.", "definition": "A condition in which the thyroid gland produces excess thyroid hormone, causing thyrotoxicosis with features such as weight loss, rapid heartbeat, heat intolerance and anxiety, arising from causes including Graves disease, toxic nodules, thyroiditis, pregnancy-related transient forms and rare congenital forms, and also occurring in cats; hyperthyroidism is diagnosed by blood tests and treated with medication, radioiodine or surgery, and this entry gives general information only, not personal medical advice.", "what_it_is_for": "Excess thyroid hormone production.", "affordances": [ "explain causes generally", "describe diagnosis and treatment", "cover the veterinary form", "route personal questions" ], "distinguishing_features": [ "Excess hormone", "Multiple causes", "Blood test diagnosis", "Treatable" ], "appearance": "Not visible as a condition; signs such as goitre may be seen.", "visual_identification": [ "Overactive thyroid", "Graves disease, nodules, thyroiditis", "Hypothyroidism is underactivity" ], "physical_properties": [], "families_and_kinds": [ "Graves disease", "toxic nodular hyperthyroidism", "thyroiditis-related thyrotoxicosis", "gestational and congenital forms", "feline hyperthyroidism" ], "related_models": [ { "relation": "is a kind of", "target": "thyroid gland disease", "why": "category" }, { "relation": "is related to", "target": "clinical sign", "why": "signs of thyrotoxicosis" }, { "relation": "is related to", "target": "radiology", "why": "thyroid imaging" }, { "relation": "is related to", "target": "deficiency", "why": "iodine and thyroid function" } ], "identifiers": [], "standards_and_regulation": [ "Clinical guidelines from endocrinology bodies", "Radioiodine treatment regulation", "Veterinary treatment standards" ], "failure_modes_and_hazards": [ "Agents giving personal medical advice", "Untreated thyrotoxicosis complications", "Confusing hyper and hypothyroidism" ], "in_scope": [], "out_of_scope": [], "characteristics": [] }, "sources": [], "structure": { "bundles": [ { "id": "understand", "name": "Understand", "description": "What hyperthyroidism is.", "rationale": "General information.", "layers": [ { "id": "causes", "name": "Causes", "description": "Causes and features.", "findings": [ { "id": "causes-finding", "name": "Causes", "description": "Causes.", "questions": [ { "text": "What causes hyperthyroidism, and what features does thyrotoxicosis produce, according to medical sources?", "kind": "provenance" }, { "text": "Is the user asking about their own health, which needs a clinician?", "kind": "boundary" } ] } ] }, { "id": "forms", "name": "Forms", "description": "Forms.", "findings": [ { "id": "forms-finding", "name": "Forms", "description": "Forms.", "questions": [ { "text": "How do Graves disease, toxic nodules, thyroiditis, gestational and congenital forms differ?", "kind": "provenance" }, { "text": "Which entry fits a specific form?", "kind": "action" } ] } ] } ] }, { "id": "care", "name": "Care", "description": "Diagnosis and treatment.", "rationale": "Medicine.", "layers": [ { "id": "diagnosis", "name": "Diagnosis", "description": "Diagnosis.", "findings": [ { "id": "diagnosis-finding", "name": "Diagnosis", "description": "Diagnosis.", "questions": [ { "text": "How is hyperthyroidism diagnosed with blood tests, antibodies and imaging, in general terms?", "kind": "provenance" }, { "text": "Are severe symptoms such as thyroid storm present, requiring urgent care?", "kind": "boundary" } ] } ] }, { "id": "treatment", "name": "Treatment", "description": "Treatment.", "findings": [ { "id": "treatment-finding", "name": "Treatment", "description": "Treatment.", "questions": [ { "text": "What treatments are documented, including antithyroid drugs, radioiodine and surgery, and how are they chosen?", "kind": "provenance" }, { "text": "Which entry fits a specific treatment?", "kind": "action" } ] } ] } ] }, { "id": "veterinary", "name": "Veterinary", "description": "Hyperthyroidism in cats.", "rationale": "Veterinary.", "layers": [ { "id": "cats", "name": "Cats", "description": "Feline hyperthyroidism.", "findings": [ { "id": "cats-finding", "name": "Cats", "description": "Cats.", "questions": [ { "text": "What is feline hyperthyroidism, and how is it diagnosed and treated?", "kind": "provenance" }, { "text": "Is a pet ill now, needing a veterinarian?", "kind": "boundary" } ] } ] }, { "id": "research", "name": "Research", "description": "Research.", "findings": [ { "id": "research-finding", "name": "Research", "description": "Research.", "questions": [ { "text": "What research addresses causes and treatments in humans and cats?", "kind": "provenance" }, { "text": "Which findings are contested?", "kind": "boundary" } ] } ] } ] }, { "id": "learn", "name": "Learn", "description": "History and teaching.", "rationale": "Education.", "layers": [ { "id": "history", "name": "History", "description": "History.", "findings": [ { "id": "history-finding", "name": "History", "description": "History.", "questions": [ { "text": "How was hyperthyroidism described by Graves, Basedow and others, and how did treatment develop?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] }, { "id": "teach", "name": "Teach", "description": "Teaching.", "findings": [ { "id": "teach-finding", "name": "Teach", "description": "Teaching.", "questions": [ { "text": "How can thyroid disorders be taught in endocrinology?", "kind": "action" }, { "text": "Which misconceptions arise?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Should each cause be a separate entry?", "How should guidelines be linked?", "How should veterinary resources be linked?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "abstract concept", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a hyperthyroidism, record what state it is in, and decide what may be done with it.", "whatItIs": "Let an agent explain hyperthyroidism and its causes in general terms with attribution, describe diagnosis and treatment as documented, cover the veterinary form, and route personal questions to clinicians.", "characteristics": { "substance": "abstract", "origin": "conceptual", "agency": "inert" }, "whatYouCanDoWithIt": [ "observed and measured" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: thyrotoxicosis with toxic single thyroid nodule, Hashitoxicosis, gestational transient thyrotoxicosis, Thyrotoxic myopathy, congenital hyperthyroidism, feline hyperthyroidism, Jod-Basedow phenomenon, Thyrotoxic periodic paralysis, thyrotoxicosis, Plummer's disease, thyrotoxic periodic paralysis, susceptibility to, 3, neonatal thyrotoxicosis.", "13 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.", "Described in 54 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a hyperthyroidism, and on what evidence are they told apart?" ], "whatItIsMadeOf": "an abstraction with no physical instance", "physicalCharacter": [ "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state" ], "howItIsRecognised": [ "Nothing to see. What is recognised is an instance of it, and which instances count is exactly what is argued about." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "thyrotoxicosis with toxic single thyroid nodule", "Hashitoxicosis", "gestational transient thyrotoxicosis", "Thyrotoxic myopathy", "congenital hyperthyroidism", "feline hyperthyroidism", "Jod-Basedow phenomenon", "Thyrotoxic periodic paralysis", "thyrotoxicosis", "Plummer's disease", "thyrotoxic periodic paralysis, susceptibility to, 3", "neonatal thyrotoxicosis" ] } ], "standing": "Described in 54 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 13 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one hyperthyroidism from another, and a hyperthyroidism from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a hyperthyroidism, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a hyperthyroidism, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a hyperthyroidism is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a hyperthyroidism, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a hyperthyroidism, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a hyperthyroidism is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a hyperthyroidism sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a hyperthyroidism, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a hyperthyroidism, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a hyperthyroidism is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a hyperthyroidism from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a hyperthyroidism, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a hyperthyroidism, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a hyperthyroidism is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a hyperthyroidism passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a hyperthyroidism between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a hyperthyroidism, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a hyperthyroidism, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a hyperthyroidism is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a hyperthyroidism, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a hyperthyroidism is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a hyperthyroidism, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a hyperthyroidism, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a hyperthyroidism is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "definitions-in-contest", "name": "Definitions and who holds them", "description": "What hyperthyroidism is taken to mean, and by whom.", "rationale": "When a field disagrees about a concept, the disagreement is the content. A model that picks one definition silently destroys the information.", "layers": [ { "id": "competing-definitions", "name": "Competing definitions", "description": "The main readings and the traditions behind them.", "findings": [ { "id": "definition-map", "name": "Definitions and their holders", "description": "Each definition with the school or body that holds it.", "questions": [ { "id": "definition-map-q01", "text": "Which definitions of hyperthyroidism are in use, and which tradition or body holds each?", "kind": "definition" }, { "id": "definition-map-q02", "text": "What turns on the difference between them in practice?", "kind": "boundary" } ] } ] }, { "id": "operationalisation", "name": "Operationalisation", "description": "How it is measured or applied when it has to be.", "findings": [ { "id": "operational-record", "name": "Measures and proxies", "description": "Instruments and indicators used to stand in for it.", "questions": [ { "id": "operational-record-q01", "text": "How is hyperthyroidism operationalised or measured in practice, and by what instrument?", "kind": "measurement" }, { "id": "operational-record-q02", "text": "What does that operationalisation leave out, and when does that matter?", "kind": "boundary" } ] } ] } ] }, { "id": "instances-and-use", "name": "Instances, use and consequence", "description": "What counts as an instance of hyperthyroidism and what follows from calling something that.", "rationale": "Applying a concept is an act with consequences, so a model must say what the label licenses and what it does not.", "layers": [ { "id": "instances", "name": "What counts as an instance", "description": "Clear cases, borderline cases and non-cases.", "findings": [ { "id": "instance-tests", "name": "Tests for an instance", "description": "What would settle whether something falls under it.", "questions": [ { "id": "instance-tests-q01", "text": "What would settle whether something is an instance of hyperthyroidism?", "kind": "boundary" }, { "id": "instance-tests-q02", "text": "Which borderline cases are argued about, and on what grounds?", "kind": "definition" } ] } ] }, { "id": "consequence", "name": "Consequence of application", "description": "Rights, duties or decisions that follow from the label.", "findings": [ { "id": "consequence-record", "name": "What the label licenses", "description": "What an agent may do once something is classified this way.", "questions": [ { "id": "consequence-record-q01", "text": "What follows practically once something is treated as hyperthyroidism?", "kind": "action" }, { "id": "consequence-record-q02", "text": "What must an agent not infer from the label alone?", "kind": "action" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a hyperthyroidism came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a hyperthyroidism and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a hyperthyroidism, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a hyperthyroidism, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a hyperthyroidism is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a hyperthyroidism is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a hyperthyroidism, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a hyperthyroidism, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a hyperthyroidism is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 5, "layers": 10, "findings": 12, "questions": 32 } } } }