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Research draft

amine

vr.tr.amine · PHY.MAT

Let an agent handle amines by structure, class, properties, uses and hazards, with safety data sheets for handling.

Thing Registry Physical world and living systems

Research draft, second pass

A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.

written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify

Researched by: Claude

Purpose and description

Let an agent handle amines by structure, class, properties, uses and hazards, with safety data sheets for handling.

An organic compound derived from ammonia by replacing one or more hydrogen atoms with alkyl or aryl groups; classed as primary, secondary or tertiary, and found in amino acids, many drugs, dyes and neurotransmitters.

What it is for: Building blocks for pharmaceuticals, dyes, polymers, surfactants and biological molecules.

It can be classify by substitution; predict basicity; synthesise and use in industry; handle with appropriate protection.

Distinguishing features

Derived from ammonia

Basic

Primary, secondary, tertiary and quaternary

Some are toxic or corrosive

What it looks like

Gases, liquids or solids, often with fishy or ammonia-like odours.

How it is recognised

Nitrogen with one to three carbon substituents

Names ending in -amine

Amides are different compounds

Related models

is a kind of - category

organic compound

is derived from - parent

ammonia

is part of - biochemistry

amino acid

is confused with - different group

amide

In practice

Families and kinds

primary amines

secondary amines

tertiary amines

aromatic amines

biogenic amines

Standards and regulation

GHS classification

REACH

IUPAC nomenclature

Failure modes and hazards

Corrosive and irritant exposure

Nitrosamine formation

Carcinogenic aromatic amines

Also called

mixed amine fuelDL-panthenol(4RS)-4-hydroxy-L-prolinebupranololmetipranololsuberedamine Asuberedamine B2-amino-3-(3-bromo-4-methoxyphenyl)-N-[2-[3,5-dibromo-4-[3-(dimethylamino)propoxy]phenyl]ethyl]propanamide3-(3-bromo-4-methoxyphenyl)-N-[2-[3,5-dibromo-4-[3-(dimethylamino)propoxy]phenyl]ethyl]-2-(methylamino)propanamidebiogenic amine4-DBeta-D(¹³C₃)Prop-2-en-1-(¹⁵N)amineallylamineamino esters2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate(2-)N(beta)-acetylstreptothricin F(2+)N(beta)-acetylstreptothricin D(4+)(2S)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamidedexpanthenoltryptamine alkaloidphenethylamine alkaloidlespedamineAmaryllidaceae alkaloidsoligoureaphenethylaminearomatic aminelumefantrineenamineoxprenolol hydrochloride3-[[6-[2-(Dimethylamino)ethyl]-1,3-benzodioxol-5-yl]methyl]-3-hydroxy-6,7-dimethoxy-2-(2-phenylethyl)isoindol-1-onehydroxylaminesaminosteroid1,4-bis(4-butylanilino)-5,8-dihydroxyanthraquinoneHibicuwanin A[4-[(Z)-3-[2-(4-hydroxyphenyl)ethylamino]-3-oxo-prop-1-enyl]-2-methoxy-phenyl] (E)-3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoate[4-[3-[2-(4-Hydroxyphenyl)ethylamino]-3-oxoprop-1-enyl]-2-methoxyphenyl] 3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate[4-(2-Aminoethyl)phenyl] 3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate4-(2-aminoethyl)phenyl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate(+)-Chelonin B

+1204

Where this came from

wikidata · CC0 1.0

Source repository Registry entry point

Also registered as vr.tr.amine

Drafted structure

Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.

Structure Which amine.

Structure defines class.

Class

Primary to tertiary.

Class

Amine class.

  1. Is it primary, secondary or tertiary? definition
  2. Aliphatic or aromatic? definition

Name

IUPAC.

Name

Nomenclature.

  1. What is its systematic name? definition
  2. What is its CAS number? provenance
Properties Chemistry.

Properties guide use.

Basicity

pKa.

Basicity

Basicity.

  1. How basic is it? measurement
  2. From which data source? provenance

Physical

State and odour.

Physical

Physical properties.

  1. What are its boiling point and solubility? measurement
  2. What is its odour? definition
Uses Applications.

Amines are widely used.

Industry

Products.

Industry

Industrial uses.

  1. What is it used for? definition
  2. In which products? definition

Biology

Biogenic amines.

Biology

Biological role.

  1. Does it occur in living systems? definition
  2. What role does it play? definition
Safety Hazards.

Many amines are hazardous.

Hazard

Classification.

Hazard

Hazard classification.

  1. How is it classified, and what protection is needed? provenance
  2. What exposure limits apply? measurement

Nitrosamines

Impurities.

Nitrosamines

Nitrosamine risk.

  1. Could nitrosamine impurities form? boundary
  2. How is this controlled? action

What the second pass must settle

  • Should amine classes be separate entries?
  • How should specific amines be linked?
  • How should nitrosamine risks be recorded?
Draft as JSON