{ "model": { "rank": 3197, "code": "thing-q170304", "model_id": "vr.tr.dopamine", "name": "dopamine", "purpose": "Enable an AI agent to identify dopamine, assess its chemical and biological state, and determine which handling, measurement or use decisions the available evidence supports.", "family": "Thing Registry", "category": "Physical world and living systems", "status": "research-draft", "kind": "thing", "plane": "PHY", "domain": "PHY.MAT", "industry": "", "version": "", "url": "/models/thing/q170304/", "tier": 2, "score": 89, "payload": { "layer": "wikidata", "aliases": [], "aliasCount": 0, "merged": 0, "knownIn": 89, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": "vr.tr.dopamine", "source": { "dataset": "wikidata", "item": "Q170304", "url": "https://www.wikidata.org/wiki/Q170304", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-07T14:06:59Z", "providers": [ "Codex" ], "breadth": "recalled by Codex without web access - no source was read", "missingProviders": [], "pass": 2, "cost": { "grok": { "seconds": 30, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.3\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a07c30-5026-7f93-a7f0-2a3a4b82d30e\n--------\nuser\nDescribe what is already known about one registered thing. Answer as JSON only, no prose around it.\n\nThing: dopamine\nSense to describe: (none recorded)\nDomain code: PHY.MAT\nAlso known as: (none)\n\n\nContext for this batch of 546 things:\n# Batch 003: 1001 registe", "usd": 0, "recall": true }, "codex": { "seconds": 83.3, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.3\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a07c30-500a-78d2-962e-a21f3e34182d\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: dopamine\nRegistry id: vr.tr.dopamine\nPlane / domain: PHY / PHY.MAT\nRegistry definition: (none recorded)\nNames folded into this entry: (none)\n\n\nContex" } } }, "metaModel": { "id": "THING-Q170304", "registryId": "vr.tr.dopamine", "name": "dopamine", "version": "0.1.0-research.1", "entryKind": "thing", "family": "Thing Registry", "domain": [ "PHY.MAT" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q170304/", "model": { "registry_id": "vr.tr.dopamine", "name": "dopamine", "purpose": "Enable an AI agent to identify dopamine, assess its chemical and biological state, and determine which handling, measurement or use decisions the available evidence supports.", "definition": "Dopamine is the catecholamine 3,4-dihydroxyphenethylamine, an endogenous signalling molecule that acts as a neurotransmitter and peripheral mediator and is a biosynthetic precursor of noradrenaline and adrenaline.", "scope_statement": "This model owns dopamine as the chemical substance registered as vr.tr.dopamine in PHY / PHY.MAT, including distinctions among molecular identity, protonation, salt form, sample quality and biological context; preparations and biological systems are related entities.", "in_scope": [ "Dopamine molecular identity and differentiation from related catecholamines and precursors", "Free-base, protonated and salt-form relationships, with form-specific identifiers", "Sample composition, purity, concentration and degradation state", "Physical properties and stability under explicitly recorded conditions", "Dopamine occurrence, biochemical transformations and receptor interactions", "Evidence supporting analytical identification, safe handling and permitted use" ], "out_of_scope": [ "Finished medicines, their formulations, prescribing and patient-specific dosing", "Complete models of neurons, synapses, organs or dopaminergic pathways", "Diseases, diagnoses and treatment plans associated with dopamine signalling", "Reward, pleasure, motivation or addiction as psychological phenomena", "Manufacturing processes and analytical instruments as independent things", "Related substances such as levodopa, norepinephrine and dopamine-derived polymers" ], "distinguishing_features": [ "The neutral parent molecule has a catechol ring bearing a two-carbon chain terminating in a primary amine; its molecular formula is C8H11NO2.", "Unlike levodopa, dopamine lacks the amino-acid carboxyl group; precursor and product must remain distinct identities.", "Unlike norepinephrine, dopamine lacks a hydroxyl group on the side-chain carbon adjacent to the aromatic ring.", "A dopamine salt contains a counterion, so its formula mass and reported mass concentration cannot automatically be treated as those of dopamine free base.", "Dopamine identity requires chemical evidence; a sample's biological effect or description as a 'reward chemical' is insufficient." ], "characteristics": [ { "name": "Chemical identity and identifier scope", "kind": "category", "unit_or_values": "Structure representation; molecular formula; verified CAS, PubChem CID and EC identifiers where applicable, each tied to a specific form", "why_it_matters": "Prevents identifiers for the neutral parent, a salt or a commercial preparation from being treated as interchangeable." }, { "name": "Chemical form", "kind": "state", "unit_or_values": "Neutral parent, protonated species or named salt; counterion and hydration state where established", "why_it_matters": "Determines the interpretation of mass, solubility, preparation instructions and reference properties." }, { "name": "Dopamine content", "kind": "measurement", "unit_or_values": "mol/L, mg/mL or mass fraction, with free-base or salt basis explicitly stated", "why_it_matters": "Makes concentration comparisons and quantity conversions reproducible." }, { "name": "Purity and impurity profile", "kind": "measurement", "unit_or_values": "Assay percentage with method and basis; identified impurities and their concentrations", "why_it_matters": "Distinguishes usable dopamine content from water, counterions, residual reagents and degradation products." }, { "name": "Physical state and reference properties", "kind": "state", "unit_or_values": "Solid or dissolved state; solvent; temperature in °C; pressure in kPa; solubility in g/L; melting or decomposition observations in °C", "why_it_matters": "Prevents condition-dependent or form-specific properties from becoming universal constants." }, { "name": "Chemical environment", "kind": "measurement", "unit_or_values": "pH, temperature in °C, elapsed time, light exposure and oxygen conditions", "why_it_matters": "Supports interpretation of protonation, oxidation risk and comparability between samples." }, { "name": "Biological location", "kind": "relation", "unit_or_values": "Organism, tissue, cell and compartment; endogenous or introduced origin", "why_it_matters": "A tissue measurement, extracellular measurement and administered quantity describe different biological situations." }, { "name": "Interaction or transformation", "kind": "relation", "unit_or_values": "Named receptor, transporter, enzyme, precursor or metabolite, with direction and supporting evidence", "why_it_matters": "Connects dopamine to biological mechanisms without assigning it a single universal effect." }, { "name": "Analytical evidence", "kind": "relation", "unit_or_values": "Method, reference standard, sample preparation, selectivity, detection limits and measurement uncertainty", "why_it_matters": "Determines whether a reported signal establishes dopamine identity or merely suggests its presence." }, { "name": "Hazard and use status", "kind": "category", "unit_or_values": "Form-specific safety classification, jurisdiction, source date, grade and documented use restrictions", "why_it_matters": "Supports handling and use decisions without transferring claims between research materials and pharmaceutical products." } ], "affordances": [ "Resolve a named material or analytical result to dopamine and its specific chemical form.", "Convert reported quantities between salt and dopamine-equivalent bases when composition and assay are established.", "Assess whether storage history and analytical evidence support continued sample use.", "Select an identification or quantification approach appropriate to the matrix and expected interferents.", "Relate dopamine measurements to specified biological compartments and mechanisms.", "Determine which handling or use decisions are supported by current form-specific documentation." ] }, "sources": [], "structure": { "bundles": [ { "id": "dopamine-identity-and-form", "name": "Dopamine identity and form", "description": "Establishes the dopamine parent structure and the exact form represented by a material record.", "rationale": "Dopamine, its salts and neighbouring catecholamines are readily conflated in names, identifiers and quantity reporting.", "layers": [ { "id": "parent-structure", "name": "Parent structure", "description": "Defines structural recognition and exclusion of related compounds.", "findings": [ { "id": "catechol-ethylamine-identity", "name": "Catechol ethylamine identity", "description": "Record structural evidence distinguishing dopamine from levodopa, norepinephrine and other similarly named substances.", "questions": [ { "text": "Which verified structure and identifiers establish that this record denotes dopamine?", "kind": "definition", "id": "catechol-ethylamine-identity-q01" }, { "text": "Which structural or analytical feature excludes levodopa and norepinephrine from this identification?", "kind": "boundary", "id": "catechol-ethylamine-identity-q02" } ] } ] }, { "id": "salt-and-protonation", "name": "Salt and protonation", "description": "Separates parent identity from counterions and condition-dependent species.", "findings": [ { "id": "form-specific-quantity-basis", "name": "Form-specific quantity basis", "description": "Record the counterion, stoichiometry, hydration and reporting basis needed to interpret a dopamine quantity.", "questions": [ { "text": "Does the material contain dopamine free base or a specified salt, and what establishes its composition?", "kind": "definition", "id": "form-specific-quantity-basis-q01" }, { "text": "Is the reported mass or concentration expressed as dopamine equivalent or as the complete salt?", "kind": "measurement", "id": "form-specific-quantity-basis-q02" }, { "text": "Which protonation assumptions are justified by the solvent and pH?", "kind": "boundary", "id": "form-specific-quantity-basis-q03" } ] } ] } ] }, { "id": "dopamine-sample-quality", "name": "Dopamine sample quality", "description": "Captures composition, physical properties and evidence that a sample remains suitable for its intended task.", "rationale": "Nominal dopamine content alone does not establish purity, physical behaviour or fitness for use.", "layers": [ { "id": "assay-and-grade", "name": "Assay and grade", "description": "Records dopamine content and the meaning of supplier or laboratory quality claims.", "findings": [ { "id": "usable-dopamine-content", "name": "Usable dopamine content", "description": "Distinguish measured dopamine content from chromatographic area purity, water content and grade labels.", "questions": [ { "text": "What assay method and calculation basis support the stated dopamine purity?", "kind": "measurement", "id": "usable-dopamine-content-q01" }, { "text": "Which lot-specific certificate or laboratory record establishes impurities, water content and grade?", "kind": "provenance", "id": "usable-dopamine-content-q02" } ] } ] }, { "id": "physical-properties-and-degradation", "name": "Physical properties and degradation", "description": "Connects form-specific properties and oxidation evidence to sample history.", "findings": [ { "id": "condition-dependent-integrity", "name": "Condition-dependent integrity", "description": "Record solvent, pH, oxygen, light, temperature and time alongside evidence of dopamine integrity or degradation.", "questions": [ { "text": "Which solubility and thermal-transition measurements apply to this exact form, and do they report decomposition?", "kind": "measurement", "id": "condition-dependent-integrity-q01" }, { "text": "What analytical evidence distinguishes intact dopamine from oxidation products, beyond a change in colour?", "kind": "measurement", "id": "condition-dependent-integrity-q02" }, { "text": "What validated storage or preparation conditions support using this sample for the intended task?", "kind": "action", "id": "condition-dependent-integrity-q03" } ] } ] } ] }, { "id": "dopamine-biological-context", "name": "Dopamine biological context", "description": "Places dopamine in defined compartments, transformations and molecular interactions.", "rationale": "The significance of dopamine depends on where it is measured and which mechanism is under examination.", "layers": [ { "id": "compartments-and-turnover", "name": "Compartments and turnover", "description": "Records biological location, origin and production or removal relationships.", "findings": [ { "id": "localized-dopamine-pool", "name": "Localized dopamine pool", "description": "Treat each biological dopamine measurement as belonging to a specified compartment and sampling interval.", "questions": [ { "text": "Which organism, tissue and intracellular or extracellular compartment does the observation represent?", "kind": "boundary", "id": "localized-dopamine-pool-q01" }, { "text": "What evidence links this dopamine pool to precursor conversion, release, uptake or metabolism?", "kind": "provenance", "id": "localized-dopamine-pool-q02" } ] } ] }, { "id": "receptor-and-transporter-relations", "name": "Receptor and transporter relations", "description": "Connects dopamine to named molecular targets and bounded experimental outcomes.", "findings": [ { "id": "contextualized-target-effect", "name": "Contextualized target effect", "description": "Separate dopamine concentration, target engagement and downstream effect as distinct observations.", "questions": [ { "text": "Which dopamine receptor subtype or transporter is implicated, and by what evidence?", "kind": "provenance", "id": "contextualized-target-effect-q01" }, { "text": "Under which concentration, exposure duration and experimental conditions was the interaction measured?", "kind": "measurement", "id": "contextualized-target-effect-q02" }, { "text": "Which claimed behavioural or physiological conclusions exceed what this molecular observation establishes?", "kind": "boundary", "id": "contextualized-target-effect-q03" } ] } ] } ] }, { "id": "dopamine-analytical-evidence", "name": "Dopamine analytical evidence", "description": "Defines what supports identifying and quantifying dopamine in a particular matrix.", "rationale": "Related catecholamines, matrix interference and sample degradation can undermine apparent dopamine measurements.", "layers": [ { "id": "identification-selectivity", "name": "Identification selectivity", "description": "Evaluates whether the analytical method separates dopamine from plausible alternatives.", "findings": [ { "id": "dopamine-specific-signal", "name": "Dopamine-specific signal", "description": "Record the reference comparison and selectivity evidence behind an assigned dopamine signal.", "questions": [ { "text": "Which reference standard and analytical features support assigning the observed signal to dopamine?", "kind": "provenance", "id": "dopamine-specific-signal-q01" }, { "text": "How does the method distinguish dopamine from related catecholamines, oxidation products and matrix interferents?", "kind": "measurement", "id": "dopamine-specific-signal-q02" } ] } ] }, { "id": "quantification-and-preservation", "name": "Quantification and preservation", "description": "Captures calibration, recovery and changes between collection and measurement.", "findings": [ { "id": "defensible-dopamine-concentration", "name": "Defensible dopamine concentration", "description": "Require a concentration result to carry its matrix, calibration basis, uncertainty and sample-preservation history.", "questions": [ { "text": "What calibration range, recovery, detection limit and uncertainty apply to this dopamine result?", "kind": "measurement", "id": "defensible-dopamine-concentration-q01" }, { "text": "How were collection, stabilisation and storage validated against dopamine loss or transformation?", "kind": "provenance", "id": "defensible-dopamine-concentration-q02" }, { "text": "Does the result represent free dopamine, a fraction released by sample treatment or another explicitly defined analyte pool?", "kind": "boundary", "id": "defensible-dopamine-concentration-q03" } ] } ] } ] }, { "id": "dopamine-handling-and-use", "name": "Dopamine handling and use", "description": "Links the exact dopamine material to supported handling practices and use qualifications.", "rationale": "Biological activity and chemical identity do not establish that a particular lot is safe or qualified for a proposed use.", "layers": [ { "id": "form-specific-hazards", "name": "Form-specific hazards", "description": "Records applicable safety evidence for the actual solid or solution.", "findings": [ { "id": "documented-exposure-controls", "name": "Documented exposure controls", "description": "Tie hazard classifications and handling controls to chemical form, concentration and current documentation.", "questions": [ { "text": "Which current safety data sheet and jurisdiction-specific classification apply to this dopamine material?", "kind": "provenance", "id": "documented-exposure-controls-q01" }, { "text": "Which controls and disposal instructions follow from its form, solvent, concentration and documented hazards?", "kind": "action", "id": "documented-exposure-controls-q02" }, { "text": "Is a substance-specific exposure limit documented, or is that information unavailable?", "kind": "provenance", "id": "documented-exposure-controls-q03" } ] } ] }, { "id": "qualified-use-boundaries", "name": "Qualified use boundaries", "description": "Separates research suitability from pharmaceutical and other regulated use requirements.", "findings": [ { "id": "lot-to-use-qualification", "name": "Lot-to-use qualification", "description": "Record evidence connecting this dopamine lot to an intended use while linking product-level decisions to the relevant neighbouring model.", "questions": [ { "text": "Which lot specifications and quality records establish suitability for the proposed analytical, research or manufacturing use?", "kind": "action", "id": "lot-to-use-qualification-q01" }, { "text": "Which decisions require a linked formulation, medicinal-product or clinical model rather than this dopamine substance model?", "kind": "boundary", "id": "lot-to-use-qualification-q02" } ] } ] } ] }, { "id": "evidence-and-external-alignment", "name": "Evidence and external alignment", "description": "What the world already says about this thing, gathered so the model can be checked against it.", "rationale": "A model that cannot be lined up against existing standards, identifiers and practice cannot be adopted by anyone who already uses them.", "layers": [ { "id": "reported-evidence", "name": "Reported evidence", "description": "Findings from the breadth pass, kept separate from the structural claims.", "findings": [ { "id": "evidence-confidence-notes", "name": "Check these first", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "This describes the chemical substance and its biological roles; pharmaceutical products require separate formulation, purity and sterility information.", "Identifiers and molar masses are recalled rather than checked against source records.", "Verify form-specific thermal properties, solubility, hazard classification, exposure limits and applicable pharmacopoeial requirements before adding them." ], "questions": [ { "id": "evidence-confidence-notes-q01", "text": "Which of these check these first hold for the sense of dopamine this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-kinds", "name": "Kinds and varieties", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Dopamine free base", "Dopamine hydrochloride" ], "questions": [ { "id": "evidence-kinds-q01", "text": "Which of these kinds and varieties hold for the sense of dopamine this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-identifiers", "name": "Identifiers and schemes", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "scheme": "CAS Registry Number", "value_or_pattern": "51-61-6", "note": "Dopamine free base." }, { "scheme": "PubChem CID", "value_or_pattern": "681", "note": "Dopamine." }, { "scheme": "CAS Registry Number", "value_or_pattern": "62-31-7", "note": "Dopamine hydrochloride; distinct from the free base." }, { "scheme": "Molecular formula", "value_or_pattern": "C8H11NO2", "note": "Neutral dopamine; this formula does not include a hydrochloride counterion." } ], "questions": [ { "id": "evidence-identifiers-q01", "text": "Which of these identifiers and schemes hold for the sense of dopamine this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-real-world-use", "name": "Real-world use", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Endogenous neurotransmission involved in movement, motivation, reinforcement learning and other functions.", "Physiological inhibition of prolactin secretion.", "Intravenous pharmaceutical use to support circulation in selected clinical circumstances.", "Research reagent for studying catecholamine receptors, transporters and metabolism.", "Starting material for polydopamine coatings used in materials research." ], "questions": [ { "id": "evidence-real-world-use-q01", "text": "Which of these real-world use hold for the sense of dopamine this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-measurements", "name": "Typical measurements", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "quantity": "Molar mass of dopamine free base", "typical_range": "153.18", "unit": "g/mol" }, { "quantity": "Molar mass of anhydrous dopamine hydrochloride", "typical_range": "189.64", "unit": "g/mol" } ], "questions": [ { "id": "evidence-measurements-q01", "text": "Which of these typical measurements hold for the sense of dopamine this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-failure-modes-and-hazards", "name": "Failure modes and hazards", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Oxidation in solution can change composition and produce coloured products; stability depends on pH, oxygen, light and storage conditions.", "Confusing free-base mass with hydrochloride-salt mass causes concentration errors.", "Administered dopamine can cause arrhythmias and excessive vasoconstriction.", "Extravasation of pharmaceutical dopamine can cause local tissue ischaemia and necrosis.", "Research-grade material is not interchangeable with a sterile pharmaceutical formulation." ], "questions": [ { "id": "evidence-failure-modes-and-hazards-q01", "text": "Which of these failure modes and hazards hold for the sense of dopamine this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-neighbours", "name": "Neighbouring kinds and how to tell them apart", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "name": "Levodopa", "difference": "Levodopa is an amino acid precursor converted to dopamine by decarboxylation; unlike dopamine, it crosses the blood-brain barrier sufficiently for central replacement therapy." }, { "name": "Noradrenaline", "difference": "Noradrenaline has an additional hydroxyl group on the side chain and is formed from dopamine by dopamine beta-hydroxylase." }, { "name": "Tyramine", "difference": "Tyramine has one phenolic hydroxyl group, whereas dopamine has two adjacent phenolic hydroxyl groups." }, { "name": "Dopamine receptor", "difference": "A dopamine receptor is a protein that responds to dopamine, not the chemical messenger itself." }, { "name": "Polydopamine", "difference": "Polydopamine is a heterogeneous material formed through dopamine oxidation and subsequent reactions, not molecular dopamine." } ], "questions": [ { "id": "evidence-neighbours-q01", "text": "Which of these neighbouring kinds and how to tell them apart hold for the sense of dopamine this model covers, and on what evidence?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Which authoritative records establish CAS, PubChem CID and EC mappings for the dopamine parent and relevant salts without conflating their identities?", "Which reliable measurements establish form-specific solubility, melting or decomposition behaviour, and whether a meaningful boiling-point value is available?", "What validated stability windows apply across relevant solvents, pH values, oxygen exposure, light conditions and temperatures?", "Which current hazard classifications, exposure limits and use restrictions apply to each intended material form and jurisdiction?", "Which analytical methods provide adequate dopamine selectivity and preservation for the intended biological or manufactured-material matrices?" ], "statistics": { "bundles": 6, "layers": 11, "findings": 17, "questions": 32 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "chemical substance or material", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a dopamine, record what state it is in, and decide what may be done with it.", "whatItIs": "Enable an AI agent to identify dopamine, assess its chemical and biological state, and determine which handling, measurement or use decisions the available evidence supports.", "characteristics": { "substance": "material", "origin": "natural", "agency": "inert", "mobility": "varies" }, "whatYouCanDoWithIt": [ "observed and measured", "consumed or used up" ], "distinguishingFeatures": [ "Described in 89 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a dopamine, and on what evidence are they told apart?" ], "whatItIsMadeOf": "matter you can touch", "physicalCharacter": [ "Mobility varies between examples.", "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state", "use it up, and then need more of it" ], "howItIsRecognised": [ "Not recognisable by sight in any reliable way. Appearance varies with grade, form and additives; identification is by label, by documentation, or by assay." ], "relatedModels": [], "standing": "Described in 89 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one dopamine from another, and a dopamine from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a dopamine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a dopamine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a dopamine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a dopamine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a dopamine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a dopamine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a dopamine sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a dopamine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a dopamine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a dopamine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a dopamine from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a dopamine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a dopamine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a dopamine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "form-and-composition", "name": "Form, composition and condition", "description": "What a dopamine is made of, what shape and size it takes, and what state it is in.", "rationale": "A physical thing can be measured, and a model that cannot record its measurements cannot support any decision that depends on them.", "layers": [ { "id": "form-and-dimensions", "name": "Form and dimensions", "description": "Shape, size, mass and the ranges these take across examples.", "findings": [ { "id": "measurable-dimensions", "name": "Measurable dimensions and their units", "description": "The quantities worth recording and the units they are recorded in.", "questions": [ { "id": "measurable-dimensions-q01", "text": "What identifies and describes the dimensions of a dopamine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "measurable-dimensions-q02", "text": "Who or what asserted this about the dimensions of a dopamine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "measurable-dimensions-q03", "text": "What may an agent decide or do once the dimensions of a dopamine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "material-and-composition", "name": "Material and composition", "description": "Materials, parts and how they are put together.", "findings": [ { "id": "parts-and-materials", "name": "Parts and materials", "description": "What a dopamine is built from and which parts are replaceable.", "questions": [ { "id": "parts-and-materials-q01", "text": "What identifies and describes the composition of a dopamine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "parts-and-materials-q02", "text": "Who or what asserted this about the composition of a dopamine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "parts-and-materials-q03", "text": "What may an agent decide or do once the composition of a dopamine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "condition-and-integrity", "name": "Condition and integrity", "description": "Wear, damage, health and the difference between working and broken.", "findings": [ { "id": "condition-assessment", "name": "Condition, damage and health", "description": "How the condition of a dopamine is judged and by whom.", "questions": [ { "id": "condition-assessment-q01", "text": "What identifies and describes the condition of a dopamine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "condition-assessment-q02", "text": "Who or what asserted this about the condition of a dopamine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "condition-assessment-q03", "text": "What may an agent decide or do once the condition of a dopamine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "place-and-movement", "name": "Place and movement", "description": "Where a dopamine is, how it got there and where it may go (varies).", "rationale": "A thing that can move needs its position recorded with a time, or every later claim about it is about a place it has left.", "layers": [ { "id": "location-and-placement", "name": "Location and placement", "description": "Position, containment and the reference frame the position is given in.", "findings": [ { "id": "position-and-frame", "name": "Position, container and reference frame", "description": "Where a dopamine is, and what that position is measured against.", "questions": [ { "id": "position-and-frame-q01", "text": "What identifies and describes the location of a dopamine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "position-and-frame-q02", "text": "Who or what asserted this about the location of a dopamine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "position-and-frame-q03", "text": "What may an agent decide or do once the location of a dopamine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "movement-and-transfer", "name": "Movement and transfer", "description": "How a dopamine is carried, installed or relocated.", "findings": [ { "id": "movement-events", "name": "Movement events and constraints", "description": "What counts as a movement, what records it and what limits it.", "questions": [ { "id": "movement-events-q01", "text": "What identifies and describes the movement of a dopamine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "movement-events-q02", "text": "Who or what asserted this about the movement of a dopamine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "movement-events-q03", "text": "What may an agent decide or do once the movement of a dopamine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a dopamine passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a dopamine between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a dopamine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a dopamine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a dopamine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a dopamine, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a dopamine is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a dopamine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a dopamine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a dopamine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "use-and-operation", "name": "Use and operation", "description": "What can be done with a dopamine and what it takes to do it.", "rationale": "An agent that can recognise a thing but not act on it has only half a model.", "layers": [ { "id": "intended-use", "name": "Intended use and function", "description": "What a dopamine is for, and what it is used for anyway.", "findings": [ { "id": "function-and-purpose", "name": "Function, purpose and misuse", "description": "The function a dopamine performs and the uses that fall outside it.", "questions": [ { "id": "function-and-purpose-q01", "text": "What identifies and describes the use of a dopamine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "function-and-purpose-q02", "text": "Who or what asserted this about the use of a dopamine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "function-and-purpose-q03", "text": "What may an agent decide or do once the use of a dopamine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "handling-and-procedure", "name": "Handling and procedure", "description": "The steps, skills and tools involved in using a dopamine.", "findings": [ { "id": "procedures-and-skills", "name": "Procedures, skills and required tools", "description": "What an agent needs before it can act on a dopamine at all.", "questions": [ { "id": "procedures-and-skills-q01", "text": "What identifies and describes handling a dopamine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "procedures-and-skills-q02", "text": "Who or what asserted this about handling a dopamine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "procedures-and-skills-q03", "text": "What may an agent decide or do once handling a dopamine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "supply-and-consumption", "name": "Supply and consumption", "description": "Quantities, rates and what running out means.", "findings": [ { "id": "consumption-and-stock", "name": "Consumption, stock and replenishment", "description": "How much of a dopamine there is and how fast it goes.", "questions": [ { "id": "consumption-and-stock-q01", "text": "What identifies and describes the supply of a dopamine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "consumption-and-stock-q02", "text": "Who or what asserted this about the supply of a dopamine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "consumption-and-stock-q03", "text": "What may an agent decide or do once the supply of a dopamine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "composition-and-identity", "name": "Composition, grade and chemical identity", "description": "What dopamine is made of and how pure the thing in hand is.", "rationale": "Grade decides what a substance may be used for, so a model that records only the name cannot support any decision about use.", "layers": [ { "id": "chemical-identity", "name": "Chemical identity", "description": "Formula, structure and the registry numbers that name it unambiguously.", "findings": [ { "id": "identity-record", "name": "Identity and registry numbers", "description": "What identifies this substance across suppliers and regulators.", "questions": [ { "id": "identity-record-q01", "text": "What formula, structure and registry identifiers name dopamine unambiguously?", "kind": "definition" }, { "id": "identity-record-q02", "text": "Which related substances share a name in common use but not an identifier?", "kind": "boundary" } ] } ] }, { "id": "grade-and-impurities", "name": "Grade, purity and impurities", "description": "The specification a batch meets and what else is in it.", "findings": [ { "id": "specification", "name": "Specification and assay", "description": "How purity is stated and measured, and which impurities matter.", "questions": [ { "id": "specification-q01", "text": "What grades of dopamine exist, how is purity assayed, and which impurities are limited?", "kind": "measurement" }, { "id": "specification-q02", "text": "Which use requires which grade, and what happens when a lower grade is substituted?", "kind": "action" } ] } ] } ] }, { "id": "properties-and-behaviour", "name": "Properties and behaviour", "description": "How dopamine behaves under conditions an agent can measure or change.", "rationale": "Physical constants are the part of a substance model that transfers between contexts, and each needs its unit and its conditions.", "layers": [ { "id": "physical-constants", "name": "Physical constants", "description": "Values that hold for the pure substance, with their conditions.", "findings": [ { "id": "constants-record", "name": "Constants and conditions", "description": "The quantities worth recording and the state they apply in.", "questions": [ { "id": "constants-record-q01", "text": "What are the defining physical constants of dopamine, in what units and under what conditions?", "kind": "measurement" }, { "id": "constants-record-q02", "text": "Which of these values change with grade or form rather than being fixed?", "kind": "boundary" } ] } ] }, { "id": "stability-and-reactivity", "name": "Stability and reactivity", "description": "What it reacts with, degrades into, and how it is stored.", "findings": [ { "id": "incompatibilities", "name": "Incompatibilities and degradation", "description": "What must not meet it, and what it becomes over time.", "questions": [ { "id": "incompatibilities-q01", "text": "What is dopamine incompatible with, and what does it degrade into under storage?", "kind": "definition" }, { "id": "incompatibilities-q02", "text": "What storage and handling does that require, and who is competent to do it?", "kind": "action" } ] } ] } ] }, { "id": "hazard-and-regulation", "name": "Hazard classification and regulation", "description": "How dopamine can harm, and what the law says about holding and moving it.", "rationale": "A substance model without its hazard class and its regulatory identity is unusable in exactly the situations that matter.", "layers": [ { "id": "hazard-class", "name": "Hazard classification", "description": "Classified hazards, exposure limits and protective measures.", "findings": [ { "id": "classified-hazards", "name": "Classified hazards and limits", "description": "The classification, the scheme it belongs to, and the limits set.", "questions": [ { "id": "classified-hazards-q01", "text": "How is dopamine classified for hazard, under which scheme, and what exposure limits apply?", "kind": "definition" }, { "id": "classified-hazards-q02", "text": "What protection does handling require, and what must an agent refuse to do without it?", "kind": "action" } ] } ] }, { "id": "regulatory-identity", "name": "Regulatory identity and control", "description": "Registration, restriction and transport rules by jurisdiction.", "findings": [ { "id": "controls", "name": "Controls and jurisdiction", "description": "Where it is restricted and what the restriction attaches to.", "questions": [ { "id": "controls-q01", "text": "Which registrations, restrictions or transport rules cover dopamine, and where?", "kind": "provenance" }, { "id": "controls-q02", "text": "Does the control attach to the substance, its concentration, or its intended use?", "kind": "boundary" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a dopamine came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a dopamine and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a dopamine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a dopamine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a dopamine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a dopamine is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a dopamine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a dopamine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a dopamine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 9, "layers": 20, "findings": 22, "questions": 60 } } } }