{ "model": { "rank": 5754, "code": "thing-q172341", "model_id": "vr.tr.ovarian-cancer", "name": "ovarian cancer", "purpose": "Let an agent give general, accurate information on ovarian cancer, encourage timely assessment of persistent symptoms, explain diagnosis and treatment pathways in general terms, and point to specialist care and support without individual medical advice.", "family": "Thing Registry", "category": "Cross-cutting context", "status": "research-draft", "kind": "thing", "plane": "XCT", "domain": "XCT.STA", "industry": "", "version": "", "url": "/models/thing/q172341/", "tier": 2, "score": 65, "payload": { "layer": "wikidata", "aliases": [ "ovarian dermoid cyst with secondary tumor", "ovarian germ cell neoplasm", "pediatric ovarian germ cell tumor", "pediatric ovarian dysgerminoma", "ovarian mucinous neoplasm", "low-grade serous carcinoma", "surface epithelial-stromal tumor", "benign ovarian mucinous tumor", "ovarian serous tumor", "malignant ovarian germ cell neoplasm", "dysgerminoma", "dermoid cyst of ovary", "malignant ovarian cyst", "ovarian melanoma", "ovarian malignant mesothelioma", "ovary sarcoma", "ovarian Wilms' cancer", "ovary neuroendocrine neoplasm", "ovarian clear cell malignant adenofibroma", "recurrent ovarian epithelial cancer", "hereditary site-specific ovarian cancer syndrome", "primary peritoneal serous/papillary carcinoma", "malignant Sertoli-leydig cell tumor of ovary", "granulosa cell tumour", "ovarian mucinous cystic tumor with mural nodules", "ovarian mucinous cystic tumor associated with pseudomyxoma peritonei", "malignant ovarian mucinous tumor", "ovarian serous carcinoma", "malignant ovarian surface epithelial-stromal neoplasm", "ovarian squamous cell neoplasm", "ovarian endometrial cancer", "ovarian papillary neoplasm", "familiar ovarian carcinoma", "borderline epithelial tumor of ovary", "borderline ovarian serous neoplasm with microinvasion", "pineal dysgerminoma", "dysgerminoma of ovary", "ovarian dermoid cyst with adenocarcinoma", "ovarian dermoid cyst with sebaceous adenoma", "ovarian dermoid cyst with secondary sebaceous tumor" ], "aliasCount": 48, "merged": 48, "knownIn": 65, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q172341", "url": "https://www.wikidata.org/wiki/Q172341", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-11T19:25:36Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 2, "engine": "claude" }, "metaModel": { "id": "THING-Q172341", "registryId": "vr.tr.ovarian-cancer", "name": "ovarian cancer", "version": "0.2.0-wave.2", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.STA" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q172341/", "model": { "registry_id": "vr.tr.ovarian-cancer", "name": "ovarian cancer", "purpose": "Let an agent give general, accurate information on ovarian cancer, encourage timely assessment of persistent symptoms, explain diagnosis and treatment pathways in general terms, and point to specialist care and support without individual medical advice.", "definition": "A cancer arising in the ovaries or, as now understood for many high-grade serous cases, in the fallopian tubes, including epithelial carcinomas, germ cell tumours and stromal tumours, often diagnosed late because early symptoms are vague; it is treated with surgery and chemotherapy and, in some cases, targeted therapies, and risk is raised by inherited variants such as BRCA1 and BRCA2.", "what_it_is_for": "A cancer requiring specialist diagnosis, treatment and support.", "affordances": [ "explain symptoms that warrant assessment", "describe types and stages in general terms", "explain treatment pathways and genetic testing", "find specialist centres and patient organisations" ], "distinguishing_features": [ "Ovarian or tubal origin", "Several histological types", "Often late diagnosis", "Hereditary risk in some families" ], "appearance": "Not physical as a concept; a diagnosis based on imaging, blood tests and pathology.", "visual_identification": [ "Persistent bloating, pelvic pain, early fullness and urinary changes", "Diagnosed by imaging, CA-125 and biopsy", "Ovarian cysts are usually benign" ], "physical_properties": [], "families_and_kinds": [ "epithelial ovarian cancer including high-grade and low-grade serous", "mucinous and endometrioid carcinomas", "germ cell tumours including dysgerminoma", "sex cord-stromal tumours", "paediatric ovarian tumours" ], "related_models": [ { "relation": "is a kind of", "target": "ovarian neoplasm", "why": "category" }, { "relation": "is a kind of", "target": "endocrine gland cancer", "why": "category" }, { "relation": "is treated by", "target": "health care", "why": "services" }, { "relation": "is related to", "target": "sex organ", "why": "organ of origin" } ], "identifiers": [], "standards_and_regulation": [ "Clinical guidelines from oncology societies such as ESMO and NCCN", "National cancer pathways and referral standards", "Genetic testing guidelines for BRCA variants" ], "failure_modes_and_hazards": [ "Delayed diagnosis", "Agents giving individual medical advice", "Unproven treatments" ], "in_scope": [], "out_of_scope": [], "characteristics": [] }, "sources": [], "structure": { "bundles": [ { "id": "symptoms", "name": "Symptoms", "description": "Early assessment.", "rationale": "Persistent symptoms need checking.", "layers": [ { "id": "warning", "name": "Warning", "description": "Symptoms to check.", "findings": [ { "id": "warning-finding", "name": "Warning", "description": "Symptoms.", "questions": [ { "text": "Are there persistent symptoms such as bloating, pelvic pain, early fullness or urinary frequency lasting weeks?", "kind": "boundary" }, { "text": "Should the person see a doctor for assessment now?", "kind": "action" } ] } ] }, { "id": "urgent", "name": "Urgent", "description": "Urgent situations.", "findings": [ { "id": "urgent-finding", "name": "Urgent", "description": "Urgent situations.", "questions": [ { "text": "Are there urgent symptoms such as severe pain, vomiting or breathlessness?", "kind": "boundary" }, { "text": "Should emergency care be sought?", "kind": "action" } ] } ] } ] }, { "id": "understand", "name": "Understand", "description": "The disease.", "rationale": "General information.", "layers": [ { "id": "types", "name": "Types", "description": "Types and stages.", "findings": [ { "id": "types-finding", "name": "Types", "description": "Types.", "questions": [ { "text": "What type and stage is being discussed, in general terms?", "kind": "definition" }, { "text": "Is the user asking about their own diagnosis or results?", "kind": "boundary" } ] } ] }, { "id": "risk", "name": "Risk", "description": "Risk factors.", "findings": [ { "id": "risk-finding", "name": "Risk", "description": "Risk factors.", "questions": [ { "text": "What do health authorities say about risk factors, including BRCA variants and family history?", "kind": "provenance" }, { "text": "Who is eligible for genetic testing?", "kind": "provenance" } ] } ] } ] }, { "id": "treatment", "name": "Treatment", "description": "Care pathway.", "rationale": "Specialist care.", "layers": [ { "id": "pathway", "name": "Pathway", "description": "Diagnosis and treatment.", "findings": [ { "id": "pathway-finding", "name": "Pathway", "description": "Pathway.", "questions": [ { "text": "How is ovarian cancer diagnosed and treated, according to guidelines, in general terms?", "kind": "provenance" }, { "text": "Which questions should be asked of the oncology team?", "kind": "action" } ] } ] }, { "id": "trials", "name": "Trials", "description": "Clinical trials.", "findings": [ { "id": "trials-finding", "name": "Trials", "description": "Trials.", "questions": [ { "text": "Which trials are recruiting, according to registries?", "kind": "provenance" }, { "text": "How can a patient discuss trials with their team?", "kind": "action" } ] } ] } ] }, { "id": "support", "name": "Support", "description": "Living with it.", "rationale": "Support helps.", "layers": [ { "id": "orgs", "name": "Organisations", "description": "Patient groups.", "findings": [ { "id": "orgs-finding", "name": "Organisations", "description": "Patient groups.", "questions": [ { "text": "Which patient organisations support people with ovarian cancer here?", "kind": "provenance" }, { "text": "Which services do they offer?", "kind": "provenance" } ] } ] }, { "id": "care", "name": "Care", "description": "Supportive care.", "findings": [ { "id": "care-finding", "name": "Care", "description": "Supportive care.", "questions": [ { "text": "What supportive and palliative care is available?", "kind": "provenance" }, { "text": "How can carers be supported?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Should each histological type be a separate entry?", "How should guidelines be linked?", "How should support organisations be localised?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "disease or condition", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a ovarian cancer, record what state it is in, and decide what may be done with it.", "whatItIs": "Let an agent give general, accurate information on ovarian cancer, encourage timely assessment of persistent symptoms, explain diagnosis and treatment pathways in general terms, and point to specialist care and support without individual medical advice.", "characteristics": { "substance": "abstract", "origin": "conceptual", "agency": "inert" }, "whatYouCanDoWithIt": [ "observed and measured" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: ovarian dermoid cyst with secondary tumor, ovarian germ cell neoplasm, pediatric ovarian germ cell tumor, pediatric ovarian dysgerminoma, ovarian mucinous neoplasm, low-grade serous carcinoma, surface epithelial-stromal tumor, benign ovarian mucinous tumor, ovarian serous tumor, malignant ovarian germ cell neoplasm, dysgerminoma, dermoid cyst of ovary.", "48 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.", "Described in 65 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a ovarian cancer, and on what evidence are they told apart?" ], "whatItIsMadeOf": "an abstraction with no physical instance", "physicalCharacter": [ "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state" ], "howItIsRecognised": [ "Recognised by criteria applied to signs and findings, not by appearance. Two conditions can look identical and be distinguished only by test." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "ovarian dermoid cyst with secondary tumor", "ovarian germ cell neoplasm", "pediatric ovarian germ cell tumor", "pediatric ovarian dysgerminoma", "ovarian mucinous neoplasm", "low-grade serous carcinoma", "surface epithelial-stromal tumor", "benign ovarian mucinous tumor", "ovarian serous tumor", "malignant ovarian germ cell neoplasm", "dysgerminoma", "dermoid cyst of ovary" ] } ], "standing": "Described in 65 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 48 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one ovarian cancer from another, and a ovarian cancer from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a ovarian cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a ovarian cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a ovarian cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a ovarian cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a ovarian cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a ovarian cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a ovarian cancer sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a ovarian cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a ovarian cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a ovarian cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a ovarian cancer from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a ovarian cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a ovarian cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a ovarian cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a ovarian cancer passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a ovarian cancer between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a ovarian cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a ovarian cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a ovarian cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a ovarian cancer, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a ovarian cancer is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a ovarian cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a ovarian cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a ovarian cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "diagnosis-and-criteria", "name": "Diagnosis, criteria and coding", "description": "What makes a case of ovarian cancer a case, and under which revision.", "rationale": "Criteria change between revisions, so a diagnosis without its coding revision cannot be compared with a later one.", "layers": [ { "id": "criteria", "name": "Diagnostic criteria", "description": "The criteria in force and who issues them.", "findings": [ { "id": "criteria-record", "name": "Criteria, issuer and revision", "description": "What must be true for a diagnosis, according to whom.", "questions": [ { "id": "criteria-record-q01", "text": "What criteria define ovarian cancer, issued by which body, in which revision?", "kind": "definition" }, { "id": "criteria-record-q02", "text": "What changed between revisions that would reclassify existing cases?", "kind": "boundary" } ] } ] }, { "id": "coding", "name": "Coding and terminology", "description": "The codes used to record it and their mapping.", "findings": [ { "id": "coding-record", "name": "Codes and mappings", "description": "Which classification codes apply and how they map.", "questions": [ { "id": "coding-record-q01", "text": "Which classification and terminology codes cover ovarian cancer, and how do they map to each other?", "kind": "definition" }, { "id": "coding-record-q02", "text": "What is lost when a case is mapped from one scheme to another?", "kind": "boundary" } ] } ] } ] }, { "id": "course-and-population", "name": "Course, population and care", "description": "How ovarian cancer develops, whom it affects, and what is done about it.", "rationale": "The condition, the diagnosis and the episode of care are three different things, and an agent must not merge them.", "layers": [ { "id": "course", "name": "Course and stages", "description": "Onset, progression, remission and outcome.", "findings": [ { "id": "course-record", "name": "Stages and transitions", "description": "The stages recorded and what moves a case between them.", "questions": [ { "id": "course-record-q01", "text": "What course does ovarian cancer typically take, and what marks each stage?", "kind": "definition" }, { "id": "course-record-q02", "text": "What separates the condition itself from an episode of care for it?", "kind": "boundary" } ] } ] }, { "id": "population", "name": "Affected populations", "description": "Who is affected, how often, and on what evidence.", "findings": [ { "id": "epidemiology", "name": "Prevalence and its basis", "description": "Rates with their population, period and source.", "questions": [ { "id": "epidemiology-q01", "text": "What prevalence or incidence is reported for ovarian cancer, in which population and period?", "kind": "measurement" }, { "id": "epidemiology-q02", "text": "What may an agent not conclude about an individual from a population rate?", "kind": "action" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a ovarian cancer came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a ovarian cancer and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a ovarian cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a ovarian cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a ovarian cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a ovarian cancer is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a ovarian cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a ovarian cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a ovarian cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 5, "layers": 10, "findings": 12, "questions": 32 } } } }