{ "model": { "rank": 5639, "code": "thing-q181003", "model_id": "vr.tr.tryptophan", "name": "tryptophan", "purpose": "Enable an agent to identify tryptophan, assess the identity and condition of a particular material, and determine its suitability for a stated use.", "family": "Thing Registry", "category": "Physical world and living systems", "status": "research-draft", "kind": "thing", "plane": "PHY", "domain": "PHY.MAT", "industry": "", "version": "", "url": "/models/thing/q181003/", "tier": 2, "score": 66, "payload": { "layer": "wikidata", "aliases": [], "aliasCount": 0, "merged": 0, "knownIn": 66, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": "vr.tr.tryptophan", "source": { "dataset": "wikidata", "item": "Q181003", "url": "https://www.wikidata.org/wiki/Q181003", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-09T22:49:30Z", "providers": [ "Codex" ], "breadth": "recalled by Codex without web access - no source was read", "missingProviders": [], "pass": 2, "cost": { "grok": { "seconds": 21.7, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a0885b-ab46-7e92-a7c6-a7e03a5cc99a\n--------\nuser\nDescribe what is already known about one registered thing. Answer as JSON only, no prose around it.\n\nThing: tryptophan\nSense to describe: (none recorded)\nDomain code: PHY.MAT\nAlso known as: (none)\n\n\nContext for this batch of 188 things:\n# Batch 006: 1001 regis", "usd": 0, "recall": true }, "codex": { "seconds": 66.9, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a0885b-ab56-7400-97b5-aac65ba900be\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: tryptophan\nRegistry id: vr.tr.tryptophan\nPlane / domain: PHY / PHY.MAT\nRegistry definition: (none recorded)\nNames folded into this entry: (none)\n\n\nCo" } } }, "metaModel": { "id": "THING-Q181003", "registryId": "vr.tr.tryptophan", "name": "tryptophan", "version": "0.1.0-research.1", "entryKind": "thing", "family": "Thing Registry", "domain": [ "PHY.MAT" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q181003/", "model": { "registry_id": "vr.tr.tryptophan", "name": "tryptophan", "purpose": "Enable an agent to identify tryptophan, assess the identity and condition of a particular material, and determine its suitability for a stated use.", "definition": "Tryptophan is an aromatic α-amino acid with an indole side chain, whose L-enantiomer is a protein-building amino acid essential in the human diet.", "scope_statement": "This model owns tryptophan as a chemical substance under registry entry vr.tr.tryptophan, including stereochemical identity, material composition, physical state, analytical evidence, biological relevance, and use constraints; it distinguishes the substance from products containing it and processes involving it.", "in_scope": [ "Tryptophan molecular identity and explicit distinction among L-, D-, racemic, and unspecified stereochemical forms", "Free amino acid material, including purity, water content, impurities, and declared grade", "Solid and dissolved states with conditions governing solubility, ionization, and stability", "Analytical evidence establishing identity, concentration, and stereochemical composition", "Biological roles and suitability constraints tied to the actual form and intended use", "Form-specific identifiers, handling requirements, and jurisdiction-dependent status" ], "out_of_scope": [ "Finished foods, supplements, medicines, and laboratory media containing tryptophan", "Whole proteins and peptides containing tryptophan residues", "Serotonin, melatonin, kynurenine, and other distinct metabolites", "Individual nutritional requirements, diagnoses, and treatment decisions", "Industrial fermentation, chemical synthesis, and purification processes as systems", "Distinct salts, derivatives, and isotopically labelled compounds as independently identified substances" ], "distinguishing_features": [ "The free amino acid has an indole-containing side chain attached through a methylene group to the alpha carbon; this distinguishes it from phenylalanine, tyrosine, and tryptamine.", "The unmodified free amino acid has molecular formula C11H12N2O2; formula agreement alone does not establish connectivity or stereochemistry.", "L-tryptophan, D-tryptophan, and their mixtures require stereochemical discrimination because molecular formula and ordinary mass measurements do not distinguish them.", "Free tryptophan has an unincorporated amino acid backbone; peptide-bound tryptophan is a residue within another molecular entity.", "A tryptophan-containing product is not the substance itself: other ingredients, concentration, and chemical form must be resolved before applying substance-level properties." ], "characteristics": [ { "name": "Stereochemical identity", "kind": "category", "unit_or_values": "L; D; racemic; quantified mixture; unspecified", "why_it_matters": "Controls identity matching, biological interpretation, and whether a reference specification applies." }, { "name": "Chemical form", "kind": "category", "unit_or_values": "Free amino acid; salt-associated form; derivative; peptide-bound residue", "why_it_matters": "Determines whether this model applies directly or must link to a neighbouring substance or macromolecule model." }, { "name": "Verified substance identifiers", "kind": "relation", "unit_or_values": "CAS, PubChem, EC, or other authoritative records with explicit stereochemical and chemical-form scope", "why_it_matters": "Prevents identifiers for different forms from being treated as interchangeable." }, { "name": "Tryptophan assay", "kind": "measurement", "unit_or_values": "% mass fraction or amount concentration, with method and as-is or dry-basis declaration", "why_it_matters": "Supports material comparison and preparation calculations without confusing assay with chromatographic area percentage." }, { "name": "Enantiomeric composition", "kind": "measurement", "unit_or_values": "L and D mole fractions, or enantiomeric excess with the major enantiomer stated", "why_it_matters": "Reveals stereochemical mixtures that an achiral purity assay can miss." }, { "name": "Water and impurity profile", "kind": "measurement", "unit_or_values": "Water in % mass fraction; identified impurities in mg/kg or % with detection limits", "why_it_matters": "Changes effective content and may constrain use independently of the main assay." }, { "name": "Physical and solution state", "kind": "state", "unit_or_values": "Solid or dissolved; solvent, temperature, pH, concentration, and observed precipitation where applicable", "why_it_matters": "Determines whether the material can be sampled, dissolved, stored, or measured as intended." }, { "name": "Solubility", "kind": "measurement", "unit_or_values": "g/L or mol/L with solvent, temperature, pH, and equilibration conditions", "why_it_matters": "Constrains solution preparation and prevents a conditional value from being treated as universal." }, { "name": "Thermal behaviour", "kind": "measurement", "unit_or_values": "°C with method and distinction among melting, decomposition, and other transitions", "why_it_matters": "Supports identification and processing decisions without assuming a clean boiling or melting event." }, { "name": "Declared grade and supported use", "kind": "category", "unit_or_values": "Supplier grade plus named specification, edition, intended use, and supporting evidence", "why_it_matters": "A grade label alone does not establish suitability for food, pharmaceutical, or analytical applications." } ], "affordances": [ "Resolve a material label to the correct tryptophan stereochemical form and authoritative identity record.", "Compare a lot's analytical evidence against a specification for a stated use.", "Calculate a preparation using verified assay, water basis, and chemical form.", "Select identity and purity measurements that distinguish tryptophan from related compounds and resolve L/D composition when needed.", "Assess dissolution, precipitation, and degradation evidence under recorded conditions.", "Assign a supported use, hold the material for further testing, or route it to the appropriate neighbouring model." ] }, "sources": [], "structure": { "bundles": [ { "id": "tryptophan-identity", "name": "Tryptophan identity", "description": "Establishes molecular connectivity, stereochemistry, and the boundary of the registered substance.", "rationale": "The name tryptophan can leave stereochemistry unspecified and can be used loosely for residues or product ingredients.", "layers": [ { "id": "molecular-recognition", "name": "Molecular recognition", "description": "Recognises the indole-containing alpha amino acid and separates it from related molecules.", "findings": [ { "id": "indole-amino-acid-identity", "name": "Indole amino acid identity", "description": "Identity requires the tryptophan connectivity, not merely an indole signal or a matching molecular formula.", "questions": [ { "text": "What structural evidence establishes the indole side chain and intact alpha amino acid backbone?", "kind": "definition", "id": "indole-amino-acid-identity-q01" }, { "text": "Does the material represent free tryptophan, a peptide-bound residue, or a distinct salt or derivative?", "kind": "boundary", "id": "indole-amino-acid-identity-q02" } ] } ] }, { "id": "stereochemistry-and-records", "name": "Stereochemistry and records", "description": "Aligns the declared stereochemical form with analytical evidence and external identity records.", "findings": [ { "id": "form-specific-identity", "name": "Form-specific identity", "description": "L, D, racemic, and unspecified tryptophan must remain distinguishable within the registry entry unless registry policy establishes another boundary.", "questions": [ { "text": "Which stereochemical form is declared, and what evidence supports that declaration?", "kind": "measurement", "id": "form-specific-identity-q01" }, { "text": "Which authoritative identifiers explicitly match that stereochemistry and chemical form?", "kind": "provenance", "id": "form-specific-identity-q02" } ] } ] } ] }, { "id": "tryptophan-material-quality", "name": "Tryptophan material quality", "description": "Describes the actual lot rather than an idealised pure molecule.", "rationale": "Assay, enantiomeric composition, water, and manufacturing-related impurities can independently change suitability.", "layers": [ { "id": "content-and-enantiomeric-purity", "name": "Content and enantiomeric purity", "description": "Separates total tryptophan content from the fraction present as the required enantiomer.", "findings": [ { "id": "assay-basis", "name": "Assay basis", "description": "A content result must state its basis and cannot substitute automatically for a stereochemical purity result.", "questions": [ { "text": "What is the measured tryptophan content, and is it reported as-is, on a dry basis, or as chromatographic area?", "kind": "measurement", "id": "assay-basis-q01" }, { "text": "What L/D composition was measured, by which chiral method, and with what reporting limit?", "kind": "measurement", "id": "assay-basis-q02" } ] } ] }, { "id": "impurities-and-grade", "name": "Impurities and grade", "description": "Relates lot-specific contaminants and water content to a named specification.", "findings": [ { "id": "lot-suitability-evidence", "name": "Lot suitability evidence", "description": "Suitability depends on the relevant impurity limits and evidence for the lot, beyond the supplier's grade label.", "questions": [ { "text": "Which related substances, residual process materials, water, and other use-relevant contaminants were measured?", "kind": "measurement", "id": "lot-suitability-evidence-q01" }, { "text": "Which specification and lot-linked certificate support acceptance for the intended use?", "kind": "provenance", "id": "lot-suitability-evidence-q02" } ] } ] } ] }, { "id": "tryptophan-physical-behaviour", "name": "Tryptophan physical behaviour", "description": "Records condition-dependent dissolution, ionization, and stability.", "rationale": "The amino acid groups and indole moiety make pH, solvent, heat, and exposure conditions relevant to material behaviour.", "layers": [ { "id": "dissolution-and-ionization", "name": "Dissolution and ionization", "description": "Connects usable solution concentration to solvent conditions and acid-base state.", "findings": [ { "id": "conditional-solubility", "name": "Conditional solubility", "description": "A solubility value applies to a specified form and environment; pH adjustment also changes the solution's ionic composition.", "questions": [ { "text": "What solubility is supported for this form at the intended temperature, pH, and solvent composition?", "kind": "measurement", "id": "conditional-solubility-q01" }, { "text": "Will the proposed dissolution or pH adjustment preserve the required chemical composition and prevent precipitation during use?", "kind": "action", "id": "conditional-solubility-q02" } ] } ] }, { "id": "thermal-and-storage-stability", "name": "Thermal and storage stability", "description": "Distinguishes phase behaviour from chemical change during heating and storage.", "findings": [ { "id": "stability-under-exposure", "name": "Stability under exposure", "description": "Thermal events and changes after light, oxygen, or moisture exposure require evidence under the relevant conditions.", "questions": [ { "text": "Does the reported thermal event represent melting, decomposition, or overlapping processes, and how was it measured?", "kind": "measurement", "id": "stability-under-exposure-q01" }, { "text": "What evidence supports storage duration and packaging for the solid or prepared solution under its actual exposure conditions?", "kind": "provenance", "id": "stability-under-exposure-q02" } ] } ] } ] }, { "id": "tryptophan-analytical-evidence", "name": "Tryptophan analytical evidence", "description": "Determines what a measurement actually establishes about tryptophan.", "rationale": "Indole optical signals are useful but not uniquely identifying, and sample preparation can change measured recovery.", "layers": [ { "id": "identity-and-signal-specificity", "name": "Identity and signal specificity", "description": "Separates screening signals from sufficiently selective identification and quantification.", "findings": [ { "id": "orthogonal-identity-evidence", "name": "Orthogonal identity evidence", "description": "UV absorption or fluorescence alone does not establish tryptophan identity, purity, or enantiomeric composition.", "questions": [ { "text": "Which chromatographic, spectrometric, or structural evidence distinguishes tryptophan from other indole-containing substances?", "kind": "measurement", "id": "orthogonal-identity-evidence-q01" }, { "text": "Which reference material and calibration evidence make the identification or concentration result traceable?", "kind": "provenance", "id": "orthogonal-identity-evidence-q02" } ] } ] }, { "id": "free-versus-total-measurement", "name": "Free versus total measurement", "description": "Defines whether an assay measures free tryptophan or tryptophan released from a larger material.", "findings": [ { "id": "sample-preparation-recovery", "name": "Sample preparation recovery", "description": "Protein hydrolysis and extraction require tryptophan-specific recovery evidence; routine acid hydrolysis can destroy tryptophan.", "questions": [ { "text": "Is the reported result free tryptophan, released protein-bound tryptophan, or a defined total?", "kind": "boundary", "id": "sample-preparation-recovery-q01" }, { "text": "How does the preparation method control or quantify tryptophan loss, incomplete release, and possible stereochemical change?", "kind": "measurement", "id": "sample-preparation-recovery-q02" } ] } ] } ] }, { "id": "tryptophan-use-and-constraints", "name": "Tryptophan use and constraints", "description": "Connects chemical identity and material evidence to biological context and permitted handling or use.", "rationale": "The biological relevance of L-tryptophan does not establish equivalent function for every form or suitability for every application.", "layers": [ { "id": "biological-role-boundaries", "name": "Biological role boundaries", "description": "Records relevant biological relationships without turning precursor status into a promised outcome.", "findings": [ { "id": "form-and-pathway-context", "name": "Form and pathway context", "description": "L-tryptophan is a proteinogenic amino acid and a precursor in multiple metabolic pathways; consequences depend on organism and conditions.", "questions": [ { "text": "Which organism, stereochemical form, and protein-synthesis or metabolic role are relevant to the intended use?", "kind": "definition", "id": "form-and-pathway-context-q01" }, { "text": "Which proposed effects require evidence from a product, biological system, or clinical model beyond this substance model?", "kind": "boundary", "id": "form-and-pathway-context-q02" } ] } ] }, { "id": "handling-and-use-eligibility", "name": "Handling and use eligibility", "description": "Checks applicable hazard information and use requirements against the actual form, lot, and jurisdiction.", "findings": [ { "id": "evidence-based-use-decision", "name": "Evidence-based use decision", "description": "Handling and use decisions require applicable documentation rather than an assumption that nutritional occurrence establishes safety or approval.", "questions": [ { "text": "Which current safety data and jurisdictional sources establish applicable GHS classification, dust controls, and any exposure limits for this material?", "kind": "provenance", "id": "evidence-based-use-decision-q01" }, { "text": "Does the lot satisfy the documented requirements for its intended use, or must it be held pending additional evidence?", "kind": "action", "id": "evidence-based-use-decision-q02" } ] } ] } ] }, { "id": "evidence-and-external-alignment", "name": "Evidence and external alignment", "description": "What the world already says about this thing, gathered so the model can be checked against it.", "rationale": "A model that cannot be lined up against existing standards, identifiers and practice cannot be adopted by anyone who already uses them.", "layers": [ { "id": "reported-evidence", "name": "Reported evidence", "description": "Findings from the breadth pass, kept separate from the structural claims.", "findings": [ { "id": "evidence-confidence-notes", "name": "Check these first", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "The unqualified registry name does not establish stereochemistry; the listed CAS number applies specifically to L-tryptophan.", "This is recalled knowledge, without source consultation; verify current monograph requirements and jurisdiction-specific rules.", "Thermal decomposition data, solubility under specified conditions, GHS classification and exposure limits need verification before inclusion." ], "questions": [ { "id": "evidence-confidence-notes-q01", "text": "Which of these check these first hold for the sense of tryptophan this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-kinds", "name": "Kinds and varieties", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "L-tryptophan", "D-tryptophan", "DL-tryptophan (racemic mixture)" ], "questions": [ { "id": "evidence-kinds-q01", "text": "Which of these kinds and varieties hold for the sense of tryptophan this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-identifiers", "name": "Identifiers and schemes", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "scheme": "CAS Registry Number", "value_or_pattern": "73-22-3", "note": "Identifies L-tryptophan; D-tryptophan and the racemate have separate identifiers." }, { "scheme": "Amino-acid residue abbreviations", "value_or_pattern": "Trp; W", "note": "Three-letter and one-letter codes used in protein sequences." }, { "scheme": "Molecular formula", "value_or_pattern": "C11H12N2O2", "note": "Shared by both enantiomers; does not distinguish stereochemistry." } ], "questions": [ { "id": "evidence-identifiers-q01", "text": "Which of these identifiers and schemes hold for the sense of tryptophan this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-standards-and-regulation", "name": "Standards and regulation", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "United States Pharmacopeia-National Formulary (USP-NF), issued by the United States Pharmacopeial Convention, includes a Tryptophan monograph specifying compendial quality requirements." ], "questions": [ { "id": "evidence-standards-and-regulation-q01", "text": "Which of these standards and regulation hold for the sense of tryptophan this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-real-world-use", "name": "Real-world use", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Incorporation of L-tryptophan into proteins during translation.", "Metabolic precursor for serotonin and, through serotonin, melatonin.", "Metabolism through the kynurenine pathway contributes to NAD biosynthesis.", "Ingredient in amino-acid nutrition formulations and dietary supplements.", "Nutritional supplementation of animal feed." ], "questions": [ { "id": "evidence-real-world-use-q01", "text": "Which of these real-world use hold for the sense of tryptophan this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-measurements", "name": "Typical measurements", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "quantity": "Molar mass", "typical_range": "204.23", "unit": "g/mol" }, { "quantity": "L-enantiomer fraction in an ideal DL racemate", "typical_range": "50", "unit": "mol%" } ], "questions": [ { "id": "evidence-measurements-q01", "text": "Which of these typical measurements hold for the sense of tryptophan this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-failure-modes-and-hazards", "name": "Failure modes and hazards", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Incorrect stereochemical identity can make material unsuitable for an application requiring L-tryptophan.", "Oxidation can alter tryptophan and reduce material or formulation quality.", "Poor aqueous solubility can limit formulation concentrations and cause precipitation.", "A historical outbreak of eosinophilia-myalgia syndrome was associated with contaminated manufactured L-tryptophan supplements; the precise causal impurities and mechanisms require careful qualification.", "Substance identity alone does not establish suitability for food, feed or pharmaceutical use; impurity controls and grade matter." ], "questions": [ { "id": "evidence-failure-modes-and-hazards-q01", "text": "Which of these failure modes and hazards hold for the sense of tryptophan this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-regional-variation", "name": "Regional variation", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Permitted uses, labeling and quality requirements depend on jurisdiction and whether the product is marketed as food, a supplement, animal feed or a medicine." ], "questions": [ { "id": "evidence-regional-variation-q01", "text": "Which of these regional variation hold for the sense of tryptophan this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-neighbours", "name": "Neighbouring kinds and how to tell them apart", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "name": "5-hydroxytryptophan", "difference": "Has an additional hydroxyl group at position 5 of the indole ring and is an intermediate between tryptophan and serotonin." }, { "name": "Tryptamine", "difference": "Lacks tryptophan's carboxyl group and can be formed by its decarboxylation." }, { "name": "Indole", "difference": "Is the fused-ring heterocycle found in tryptophan's side chain, without the amino-acid substituent." }, { "name": "Tryptophan-containing supplement", "difference": "Is a formulated product whose dose, additional ingredients and impurities are distinct from the chemical substance." } ], "questions": [ { "id": "evidence-neighbours-q01", "text": "Which of these neighbouring kinds and how to tell them apart hold for the sense of tryptophan this model covers, and on what evidence?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Does the registry intend unqualified tryptophan to cover all stereochemical forms or primarily L-tryptophan, and how should form-specific external records be linked?", "Which authoritative CAS, PubChem, and EC records match each included form without conflating free tryptophan with salts or derivatives?", "Which experimentally supported solubility, acid-base, thermal, and storage-stability values are appropriate, with their measurement conditions and uncertainties?", "Which impurity panels, analytical methods, and acceptance limits apply to the intended grades and uses?", "What current jurisdiction-specific hazard classifications, exposure limits if any, and food or pharmaceutical requirements apply to the material being modelled?" ], "statistics": { "bundles": 6, "layers": 11, "findings": 19, "questions": 29 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "chemical substance or material", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a tryptophan, record what state it is in, and decide what may be done with it.", "whatItIs": "Enable an agent to identify tryptophan, assess the identity and condition of a particular material, and determine its suitability for a stated use.", "characteristics": { "substance": "material", "origin": "natural", "agency": "inert", "mobility": "varies" }, "whatYouCanDoWithIt": [ "observed and measured", "consumed or used up" ], "distinguishingFeatures": [ "Described in 66 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a tryptophan, and on what evidence are they told apart?" ], "whatItIsMadeOf": "matter you can touch", "physicalCharacter": [ "Mobility varies between examples.", "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state", "use it up, and then need more of it" ], "howItIsRecognised": [ "Not recognisable by sight in any reliable way. Appearance varies with grade, form and additives; identification is by label, by documentation, or by assay." ], "relatedModels": [], "standing": "Described in 66 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one tryptophan from another, and a tryptophan from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a tryptophan, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a tryptophan, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a tryptophan is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a tryptophan, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a tryptophan, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a tryptophan is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a tryptophan sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a tryptophan, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a tryptophan, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a tryptophan is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a tryptophan from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a tryptophan, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a tryptophan, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a tryptophan is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "form-and-composition", "name": "Form, composition and condition", "description": "What a tryptophan is made of, what shape and size it takes, and what state it is in.", "rationale": "A physical thing can be measured, and a model that cannot record its measurements cannot support any decision that depends on them.", "layers": [ { "id": "form-and-dimensions", "name": "Form and dimensions", "description": "Shape, size, mass and the ranges these take across examples.", "findings": [ { "id": "measurable-dimensions", "name": "Measurable dimensions and their units", "description": "The quantities worth recording and the units they are recorded in.", "questions": [ { "id": "measurable-dimensions-q01", "text": "What identifies and describes the dimensions of a tryptophan, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "measurable-dimensions-q02", "text": "Who or what asserted this about the dimensions of a tryptophan, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "measurable-dimensions-q03", "text": "What may an agent decide or do once the dimensions of a tryptophan is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "material-and-composition", "name": "Material and composition", "description": "Materials, parts and how they are put together.", "findings": [ { "id": "parts-and-materials", "name": "Parts and materials", "description": "What a tryptophan is built from and which parts are replaceable.", "questions": [ { "id": "parts-and-materials-q01", "text": "What identifies and describes the composition of a tryptophan, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "parts-and-materials-q02", "text": "Who or what asserted this about the composition of a tryptophan, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "parts-and-materials-q03", "text": "What may an agent decide or do once the composition of a tryptophan is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "condition-and-integrity", "name": "Condition and integrity", "description": "Wear, damage, health and the difference between working and broken.", "findings": [ { "id": "condition-assessment", "name": "Condition, damage and health", "description": "How the condition of a tryptophan is judged and by whom.", "questions": [ { "id": "condition-assessment-q01", "text": "What identifies and describes the condition of a tryptophan, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "condition-assessment-q02", "text": "Who or what asserted this about the condition of a tryptophan, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "condition-assessment-q03", "text": "What may an agent decide or do once the condition of a tryptophan is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "place-and-movement", "name": "Place and movement", "description": "Where a tryptophan is, how it got there and where it may go (varies).", "rationale": "A thing that can move needs its position recorded with a time, or every later claim about it is about a place it has left.", "layers": [ { "id": "location-and-placement", "name": "Location and placement", "description": "Position, containment and the reference frame the position is given in.", "findings": [ { "id": "position-and-frame", "name": "Position, container and reference frame", "description": "Where a tryptophan is, and what that position is measured against.", "questions": [ { "id": "position-and-frame-q01", "text": "What identifies and describes the location of a tryptophan, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "position-and-frame-q02", "text": "Who or what asserted this about the location of a tryptophan, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "position-and-frame-q03", "text": "What may an agent decide or do once the location of a tryptophan is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "movement-and-transfer", "name": "Movement and transfer", "description": "How a tryptophan is carried, installed or relocated.", "findings": [ { "id": "movement-events", "name": "Movement events and constraints", "description": "What counts as a movement, what records it and what limits it.", "questions": [ { "id": "movement-events-q01", "text": "What identifies and describes the movement of a tryptophan, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "movement-events-q02", "text": "Who or what asserted this about the movement of a tryptophan, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "movement-events-q03", "text": "What may an agent decide or do once the movement of a tryptophan is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a tryptophan passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a tryptophan between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a tryptophan, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a tryptophan, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a tryptophan is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a tryptophan, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a tryptophan is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a tryptophan, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a tryptophan, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a tryptophan is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "use-and-operation", "name": "Use and operation", "description": "What can be done with a tryptophan and what it takes to do it.", "rationale": "An agent that can recognise a thing but not act on it has only half a model.", "layers": [ { "id": "intended-use", "name": "Intended use and function", "description": "What a tryptophan is for, and what it is used for anyway.", "findings": [ { "id": "function-and-purpose", "name": "Function, purpose and misuse", "description": "The function a tryptophan performs and the uses that fall outside it.", "questions": [ { "id": "function-and-purpose-q01", "text": "What identifies and describes the use of a tryptophan, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "function-and-purpose-q02", "text": "Who or what asserted this about the use of a tryptophan, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "function-and-purpose-q03", "text": "What may an agent decide or do once the use of a tryptophan is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "handling-and-procedure", "name": "Handling and procedure", "description": "The steps, skills and tools involved in using a tryptophan.", "findings": [ { "id": "procedures-and-skills", "name": "Procedures, skills and required tools", "description": "What an agent needs before it can act on a tryptophan at all.", "questions": [ { "id": "procedures-and-skills-q01", "text": "What identifies and describes handling a tryptophan, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "procedures-and-skills-q02", "text": "Who or what asserted this about handling a tryptophan, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "procedures-and-skills-q03", "text": "What may an agent decide or do once handling a tryptophan is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "supply-and-consumption", "name": "Supply and consumption", "description": "Quantities, rates and what running out means.", "findings": [ { "id": "consumption-and-stock", "name": "Consumption, stock and replenishment", "description": "How much of a tryptophan there is and how fast it goes.", "questions": [ { "id": "consumption-and-stock-q01", "text": "What identifies and describes the supply of a tryptophan, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "consumption-and-stock-q02", "text": "Who or what asserted this about the supply of a tryptophan, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "consumption-and-stock-q03", "text": "What may an agent decide or do once the supply of a tryptophan is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "composition-and-identity", "name": "Composition, grade and chemical identity", "description": "What tryptophan is made of and how pure the thing in hand is.", "rationale": "Grade decides what a substance may be used for, so a model that records only the name cannot support any decision about use.", "layers": [ { "id": "chemical-identity", "name": "Chemical identity", "description": "Formula, structure and the registry numbers that name it unambiguously.", "findings": [ { "id": "identity-record", "name": "Identity and registry numbers", "description": "What identifies this substance across suppliers and regulators.", "questions": [ { "id": "identity-record-q01", "text": "What formula, structure and registry identifiers name tryptophan unambiguously?", "kind": "definition" }, { "id": "identity-record-q02", "text": "Which related substances share a name in common use but not an identifier?", "kind": "boundary" } ] } ] }, { "id": "grade-and-impurities", "name": "Grade, purity and impurities", "description": "The specification a batch meets and what else is in it.", "findings": [ { "id": "specification", "name": "Specification and assay", "description": "How purity is stated and measured, and which impurities matter.", "questions": [ { "id": "specification-q01", "text": "What grades of tryptophan exist, how is purity assayed, and which impurities are limited?", "kind": "measurement" }, { "id": "specification-q02", "text": "Which use requires which grade, and what happens when a lower grade is substituted?", "kind": "action" } ] } ] } ] }, { "id": "properties-and-behaviour", "name": "Properties and behaviour", "description": "How tryptophan behaves under conditions an agent can measure or change.", "rationale": "Physical constants are the part of a substance model that transfers between contexts, and each needs its unit and its conditions.", "layers": [ { "id": "physical-constants", "name": "Physical constants", "description": "Values that hold for the pure substance, with their conditions.", "findings": [ { "id": "constants-record", "name": "Constants and conditions", "description": "The quantities worth recording and the state they apply in.", "questions": [ { "id": "constants-record-q01", "text": "What are the defining physical constants of tryptophan, in what units and under what conditions?", "kind": "measurement" }, { "id": "constants-record-q02", "text": "Which of these values change with grade or form rather than being fixed?", "kind": "boundary" } ] } ] }, { "id": "stability-and-reactivity", "name": "Stability and reactivity", "description": "What it reacts with, degrades into, and how it is stored.", "findings": [ { "id": "incompatibilities", "name": "Incompatibilities and degradation", "description": "What must not meet it, and what it becomes over time.", "questions": [ { "id": "incompatibilities-q01", "text": "What is tryptophan incompatible with, and what does it degrade into under storage?", "kind": "definition" }, { "id": "incompatibilities-q02", "text": "What storage and handling does that require, and who is competent to do it?", "kind": "action" } ] } ] } ] }, { "id": "hazard-and-regulation", "name": "Hazard classification and regulation", "description": "How tryptophan can harm, and what the law says about holding and moving it.", "rationale": "A substance model without its hazard class and its regulatory identity is unusable in exactly the situations that matter.", "layers": [ { "id": "hazard-class", "name": "Hazard classification", "description": "Classified hazards, exposure limits and protective measures.", "findings": [ { "id": "classified-hazards", "name": "Classified hazards and limits", "description": "The classification, the scheme it belongs to, and the limits set.", "questions": [ { "id": "classified-hazards-q01", "text": "How is tryptophan classified for hazard, under which scheme, and what exposure limits apply?", "kind": "definition" }, { "id": "classified-hazards-q02", "text": "What protection does handling require, and what must an agent refuse to do without it?", "kind": "action" } ] } ] }, { "id": "regulatory-identity", "name": "Regulatory identity and control", "description": "Registration, restriction and transport rules by jurisdiction.", "findings": [ { "id": "controls", "name": "Controls and jurisdiction", "description": "Where it is restricted and what the restriction attaches to.", "questions": [ { "id": "controls-q01", "text": "Which registrations, restrictions or transport rules cover tryptophan, and where?", "kind": "provenance" }, { "id": "controls-q02", "text": "Does the control attach to the substance, its concentration, or its intended use?", "kind": "boundary" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a tryptophan came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a tryptophan and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a tryptophan, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a tryptophan, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a tryptophan is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a tryptophan is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a tryptophan, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a tryptophan, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a tryptophan is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 9, "layers": 20, "findings": 22, "questions": 60 } } } }