{ "model": { "rank": 6766, "code": "thing-q184559", "model_id": "vr.tr.arteriosclerosis", "name": "arteriosclerosis", "purpose": "Let an agent explain arteriosclerosis and its kinds in general terms, relay causes, consequences and prevention from cardiovascular guidelines, distinguish it from atherosclerosis as a subtype, and route personal concerns to clinicians.", "family": "Thing Registry", "category": "Cross-cutting context", "status": "research-draft", "kind": "thing", "plane": "XCT", "domain": "XCT.STA", "industry": "", "version": "", "url": "/models/thing/q184559/", "tier": 2, "score": 58, "payload": { "layer": "wikidata", "aliases": [ "intermittent claudication", "Determann syndrome", "Monckeberg arteriosclerosis", "intracranial arteriosclerosis" ], "aliasCount": 4, "merged": 4, "knownIn": 58, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q184559", "url": "https://www.wikidata.org/wiki/Q184559", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-12T23:55:52Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 3, "engine": "claude" }, "metaModel": { "id": "THING-Q184559", "registryId": "vr.tr.arteriosclerosis", "name": "arteriosclerosis", "version": "0.2.0-wave.3", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.STA" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q184559/", "model": { "registry_id": "vr.tr.arteriosclerosis", "name": "arteriosclerosis", "purpose": "Let an agent explain arteriosclerosis and its kinds in general terms, relay causes, consequences and prevention from cardiovascular guidelines, distinguish it from atherosclerosis as a subtype, and route personal concerns to clinicians.", "definition": "A group of diseases in which artery walls thicken, stiffen and lose elasticity, including atherosclerosis from plaque build-up, Monckeberg medial calcification and arteriolosclerosis of small vessels, with intracranial forms affecting brain arteries; arteriosclerosis reduces blood flow and causes conditions such as intermittent claudication, heart attack and stroke, is driven by age, smoking, high blood pressure, diabetes and cholesterol, and is managed by risk reduction, medicines and procedures.", "what_it_is_for": "Not applicable; a group of diseases.", "affordances": [ "explain kinds and mechanisms", "relay consequences and prevention", "distinguish subtypes", "route personal concerns to clinicians" ], "distinguishing_features": [ "Arterial wall change", "Multiple subtypes", "Major cause of heart attack and stroke", "Modifiable risk factors" ], "appearance": "Not a visible object; thickened, stiffened arteries seen on imaging and in pathology.", "visual_identification": [ "Thickening and stiffening of artery walls", "Atherosclerosis, medial calcification and arteriolosclerosis", "Atherosclerosis is the plaque subtype; aneurysm is a different arterial disease" ], "physical_properties": [ { "quantity": "cardiovascular disease deaths worldwide", "typical_range": "about 18 million", "unit": "per year", "note": "WHO estimate, all causes" } ], "families_and_kinds": [ "atherosclerosis", "Monckeberg medial calcific sclerosis", "arteriolosclerosis", "intracranial arteriosclerosis", "peripheral arterial disease with intermittent claudication", "rare syndromes such as Determann syndrome" ], "related_models": [ { "relation": "is a kind of", "target": "artery disease", "why": "in registry terms" }, { "relation": "includes", "target": "atherosclerosis", "why": "the main subtype" }, { "relation": "causes", "target": "peripheral artery disease", "why": "and coronary and cerebrovascular disease" }, { "relation": "is prevented by", "target": "cardiovascular risk reduction", "why": "lifestyle and medicines" } ], "identifiers": [ { "scheme": "ICD-10", "value_or_pattern": "I70", "note": "atherosclerosis" }, { "scheme": "ICD-11", "value_or_pattern": "BD40", "note": "atherosclerotic chronic arterial occlusive disease" } ], "standards_and_regulation": [ "Cardiovascular prevention guidelines", "Guidelines on peripheral arterial disease", "Public health policies on smoking, diet and blood pressure" ], "failure_modes_and_hazards": [ "Heart attack, stroke and limb ischaemia", "Missed peripheral disease", "Agents giving personal medical advice" ], "in_scope": [], "out_of_scope": [], "characteristics": [] }, "sources": [], "structure": { "bundles": [ { "id": "understand", "name": "Understand", "description": "What arteriosclerosis is.", "rationale": "General information.", "layers": [ { "id": "definition", "name": "Definition", "description": "Definition and kinds.", "findings": [ { "id": "definition-finding", "name": "Definition", "description": "Definition.", "questions": [ { "text": "What is arteriosclerosis, and how do atherosclerosis, medial calcification and arteriolosclerosis differ?", "kind": "definition" }, { "text": "Is the user describing chest pain, leg pain or neurological symptoms, which need urgent assessment?", "kind": "boundary" } ] } ] }, { "id": "causes", "name": "Causes", "description": "Causes and risk factors.", "findings": [ { "id": "causes-finding", "name": "Causes", "description": "Causes.", "questions": [ { "text": "What causes arteriosclerosis, and what risk factors do guidelines identify?", "kind": "definition" }, { "text": "Which entry fits the specific subtype?", "kind": "action" } ] } ] } ] }, { "id": "clinical", "name": "Clinical", "description": "Consequences and management.", "rationale": "Clinical.", "layers": [ { "id": "consequences", "name": "Consequences", "description": "Consequences.", "findings": [ { "id": "consequences-finding", "name": "Consequences", "description": "Consequences.", "questions": [ { "text": "What conditions result, from intermittent claudication to heart attack and stroke?", "kind": "provenance" }, { "text": "Is the presentation free of personal medical advice?", "kind": "boundary" } ] } ] }, { "id": "management", "name": "Management", "description": "Management principles.", "findings": [ { "id": "management-finding", "name": "Management", "description": "Management.", "questions": [ { "text": "What prevention and treatment principles do guidelines describe, in general terms?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] } ] }, { "id": "public", "name": "Public health", "description": "Burden and prevention.", "rationale": "Public health.", "layers": [ { "id": "burden", "name": "Burden", "description": "Burden.", "findings": [ { "id": "burden-finding", "name": "Burden", "description": "Burden.", "questions": [ { "text": "What do health bodies report about the burden of arterial disease, with sources?", "kind": "measurement" }, { "text": "Which sources are cited?", "kind": "provenance" } ] } ] }, { "id": "prevention", "name": "Prevention", "description": "Population prevention.", "findings": [ { "id": "prevention-finding", "name": "Prevention", "description": "Prevention.", "questions": [ { "text": "What population measures reduce arteriosclerosis, with evidence attributed?", "kind": "provenance" }, { "text": "Which entry fits cardiovascular disease prevention?", "kind": "action" } ] } ] } ] }, { "id": "context", "name": "Context", "description": "Research and history.", "rationale": "Context.", "layers": [ { "id": "research", "name": "Research", "description": "Research.", "findings": [ { "id": "research-finding", "name": "Research", "description": "Research.", "questions": [ { "text": "What are current research directions, such as inflammation and new lipid therapies?", "kind": "provenance" }, { "text": "Which entry fits cardiology?", "kind": "action" } ] } ] }, { "id": "history", "name": "History", "description": "History.", "findings": [ { "id": "history-finding", "name": "History", "description": "History.", "questions": [ { "text": "How was arteriosclerosis understood historically, and how did risk factor epidemiology develop?", "kind": "provenance" }, { "text": "Which entry fits the Framingham Heart Study?", "kind": "action" } ] } ] } ] } ] }, "openQuestions": [ "Should atherosclerosis be the primary entry?", "How should guidelines be linked?", "The registry entry has merged aliases naming symptoms and rare syndromes; should they be split off?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "disease or condition", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a arteriosclerosis, record what state it is in, and decide what may be done with it.", "whatItIs": "Let an agent explain arteriosclerosis and its kinds in general terms, relay causes, consequences and prevention from cardiovascular guidelines, distinguish it from atherosclerosis as a subtype, and route personal concerns to clinicians.", "characteristics": { "substance": "abstract", "origin": "conceptual", "agency": "inert" }, "whatYouCanDoWithIt": [ "observed and measured" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: intermittent claudication, Determann syndrome, Monckeberg arteriosclerosis, intracranial arteriosclerosis.", "4 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.", "Described in 58 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a arteriosclerosis, and on what evidence are they told apart?" ], "whatItIsMadeOf": "an abstraction with no physical instance", "physicalCharacter": [ "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state" ], "howItIsRecognised": [ "Recognised by criteria applied to signs and findings, not by appearance. Two conditions can look identical and be distinguished only by test." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "intermittent claudication", "Determann syndrome", "Monckeberg arteriosclerosis", "intracranial arteriosclerosis" ] } ], "standing": "Described in 58 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 4 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one arteriosclerosis from another, and a arteriosclerosis from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a arteriosclerosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a arteriosclerosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a arteriosclerosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a arteriosclerosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a arteriosclerosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a arteriosclerosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a arteriosclerosis sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a arteriosclerosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a arteriosclerosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a arteriosclerosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a arteriosclerosis from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a arteriosclerosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a arteriosclerosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a arteriosclerosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a arteriosclerosis passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a arteriosclerosis between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a arteriosclerosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a arteriosclerosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a arteriosclerosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a arteriosclerosis, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a arteriosclerosis is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a arteriosclerosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a arteriosclerosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a arteriosclerosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "diagnosis-and-criteria", "name": "Diagnosis, criteria and coding", "description": "What makes a case of arteriosclerosis a case, and under which revision.", "rationale": "Criteria change between revisions, so a diagnosis without its coding revision cannot be compared with a later one.", "layers": [ { "id": "criteria", "name": "Diagnostic criteria", "description": "The criteria in force and who issues them.", "findings": [ { "id": "criteria-record", "name": "Criteria, issuer and revision", "description": "What must be true for a diagnosis, according to whom.", "questions": [ { "id": "criteria-record-q01", "text": "What criteria define arteriosclerosis, issued by which body, in which revision?", "kind": "definition" }, { "id": "criteria-record-q02", "text": "What changed between revisions that would reclassify existing cases?", "kind": "boundary" } ] } ] }, { "id": "coding", "name": "Coding and terminology", "description": "The codes used to record it and their mapping.", "findings": [ { "id": "coding-record", "name": "Codes and mappings", "description": "Which classification codes apply and how they map.", "questions": [ { "id": "coding-record-q01", "text": "Which classification and terminology codes cover arteriosclerosis, and how do they map to each other?", "kind": "definition" }, { "id": "coding-record-q02", "text": "What is lost when a case is mapped from one scheme to another?", "kind": "boundary" } ] } ] } ] }, { "id": "course-and-population", "name": "Course, population and care", "description": "How arteriosclerosis develops, whom it affects, and what is done about it.", "rationale": "The condition, the diagnosis and the episode of care are three different things, and an agent must not merge them.", "layers": [ { "id": "course", "name": "Course and stages", "description": "Onset, progression, remission and outcome.", "findings": [ { "id": "course-record", "name": "Stages and transitions", "description": "The stages recorded and what moves a case between them.", "questions": [ { "id": "course-record-q01", "text": "What course does arteriosclerosis typically take, and what marks each stage?", "kind": "definition" }, { "id": "course-record-q02", "text": "What separates the condition itself from an episode of care for it?", "kind": "boundary" } ] } ] }, { "id": "population", "name": "Affected populations", "description": "Who is affected, how often, and on what evidence.", "findings": [ { "id": "epidemiology", "name": "Prevalence and its basis", "description": "Rates with their population, period and source.", "questions": [ { "id": "epidemiology-q01", "text": "What prevalence or incidence is reported for arteriosclerosis, in which population and period?", "kind": "measurement" }, { "id": "epidemiology-q02", "text": "What may an agent not conclude about an individual from a population rate?", "kind": "action" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a arteriosclerosis came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a arteriosclerosis and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a arteriosclerosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a arteriosclerosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a arteriosclerosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a arteriosclerosis is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a arteriosclerosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a arteriosclerosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a arteriosclerosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 5, "layers": 10, "findings": 12, "questions": 32 } } } }