{ "model": { "rank": 6220, "code": "thing-q184564", "model_id": "vr.tr.aldosterone", "name": "aldosterone", "purpose": "Enable an AI agent to recognise aldosterone, assess the identity and fitness of a material or measurement, and determine which handling, analytical or biological interpretations are justified.", "family": "Thing Registry", "category": "Physical world and living systems", "status": "research-draft", "kind": "thing", "plane": "PHY", "domain": "PHY.MAT", "industry": "", "version": "", "url": "/models/thing/q184564/", "tier": 2, "score": 61, "payload": { "layer": "wikidata", "aliases": [], "aliasCount": 0, "merged": 0, "knownIn": 61, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q184564", "url": "https://www.wikidata.org/wiki/Q184564", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-09T22:56:09Z", "providers": [ "Codex" ], "breadth": "recalled by Codex without web access - no source was read", "missingProviders": [], "pass": 2, "cost": { "grok": { "seconds": 20.1, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a08861-e1d8-7811-b2fb-824603f8e861\n--------\nuser\nDescribe what is already known about one registered thing. Answer as JSON only, no prose around it.\n\nThing: aldosterone\nSense to describe: (none recorded)\nDomain code: PHY.MAT\nAlso known as: (none)\n\n\nContext for this batch of 188 things:\n# Batch 006: 1001 regi", "usd": 0, "recall": true }, "codex": { "seconds": 58.6, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a08861-e1ce-7f82-90ad-40d38276ebf6\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: aldosterone\nRegistry id: vr.tr.aldosterone\nPlane / domain: PHY / PHY.MAT\nRegistry definition: (none recorded)\nNames folded into this entry: (none)\n\n\n" } } }, "metaModel": { "id": "THING-Q184564", "registryId": "vr.tr.aldosterone", "name": "aldosterone", "version": "0.1.0-research.1", "entryKind": "thing", "family": "Thing Registry", "domain": [ "PHY.MAT" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q184564/", "model": { "registry_id": "vr.tr.aldosterone", "name": "aldosterone", "purpose": "Enable an AI agent to recognise aldosterone, assess the identity and fitness of a material or measurement, and determine which handling, analytical or biological interpretations are justified.", "definition": "Aldosterone is a C21 steroid mineralocorticoid hormone produced chiefly by the adrenal cortex's zona glomerulosa that promotes renal sodium reabsorption and potassium excretion through mineralocorticoid receptor activation, helping regulate extracellular fluid volume and blood pressure.", "scope_statement": "This model owns aldosterone as a chemically specified substance, including its material forms, biological context, analytical identification and use constraints; it distinguishes molecular identity from preparation quality and measured concentration.", "in_scope": [ "Chemical identity, stereochemistry and verified substance identifiers", "Aldosterone preparations, purity, concentration, impurities and storage state", "Endogenous production, molecular targets and transformations as contextual relationships", "Measurement of aldosterone in biological specimens and laboratory preparations", "Evidence governing handling, analytical suitability and permitted uses" ], "out_of_scope": [ "Complete models of adrenal glands, kidneys or endocrine regulatory systems", "Diagnosis and treatment of disorders associated with aldosterone", "Mineralocorticoid receptor antagonists and other distinct compounds", "Finished medicinal products, assay kits and their complete specifications", "Detailed manufacturing processes and clinical testing protocols" ], "distinguishing_features": [ "Require agreement with a verified aldosterone structure, including stereochemistry, rather than accepting a steroid-family label or molecular formula alone.", "Distinguish aldosterone from related steroids such as corticosterone and cortisol through structure-specific identification or demonstrated analytical separation.", "Identify isotope-labelled aldosterone separately from unlabelled aldosterone when evaluating reference materials and analytical results.", "Separate unconjugated aldosterone from conjugates, metabolites and quantities reported after hydrolysis.", "Distinguish the substance from an aldosterone-containing solution, biological specimen or product by recording the surrounding matrix and actual aldosterone content." ], "characteristics": [ { "name": "Verified chemical identity", "kind": "category", "unit_or_values": "Structure, stereochemistry, molecular formula and source-verified CAS, PubChem and applicable regulatory identifiers", "why_it_matters": "Prevents a synonym, related steroid or preparation identifier from being mistaken for the substance." }, { "name": "Isotopic and chemical form", "kind": "category", "unit_or_values": "Unlabelled parent; specified isotope-labelled form; conjugate or derivative requiring a separate identity", "why_it_matters": "Determines whether a material represents aldosterone itself, an analytical standard or a neighbouring substance." }, { "name": "Preparation and matrix", "kind": "category", "unit_or_values": "Neat material; solution with named solvent; biological specimen with named matrix", "why_it_matters": "Controls how concentration, stability, hazards and analytical suitability should be interpreted." }, { "name": "Purity and impurity profile", "kind": "measurement", "unit_or_values": "Percent with stated basis and method; identified impurities and their amounts", "why_it_matters": "A chromatographic purity result alone may not establish the amount of aldosterone available for calibration." }, { "name": "Aldosterone content or concentration", "kind": "measurement", "unit_or_values": "Mass fraction, mol/L or mass/volume with uncertainty, matrix and measurement method", "why_it_matters": "Makes quantities comparable while preserving the distinction between stock solutions and specimen results." }, { "name": "Physical properties under stated conditions", "kind": "measurement", "unit_or_values": "Phase; melting or decomposition behaviour in °C; solubility with solvent and temperature; boiling data only if established", "why_it_matters": "Supports preparation and handling without treating unsupported constants as known." }, { "name": "Storage and stability status", "kind": "state", "unit_or_values": "Documented conditions met; excursion recorded; expired; stability unverified", "why_it_matters": "Determines whether an identified material remains fit for its intended use." }, { "name": "Biological production and action", "kind": "relation", "unit_or_values": "Evidence-linked producing tissue, regulatory inputs, molecular targets and transformations, with species and experimental context", "why_it_matters": "Connects aldosterone to physiology without attributing an entire organism's condition to one substance measurement." }, { "name": "Hazard and use status", "kind": "category", "unit_or_values": "Source-dated classification, applicable jurisdiction, preparation-specific safety information and documented use restrictions", "why_it_matters": "Prevents safety or suitability claims for one preparation from being transferred to another." } ], "affordances": [ "Resolve a name or identifier to a verified aldosterone identity and flag conflicting records.", "Evaluate whether an aldosterone lot or stock solution is suitable for a specified analytical or research task.", "Compare aldosterone measurements after checking units, analyte definition, matrix and method.", "Trace an aldosterone preparation or result to its source, certificate and supporting evidence.", "Identify missing biological context that prevents interpretation of an aldosterone result.", "Select documented handling and storage requirements for the actual preparation." ] }, "sources": [], "structure": { "bundles": [ { "id": "aldosterone-identity", "name": "Aldosterone identity", "description": "Establishes which molecular entity a name, material or analytical result denotes.", "rationale": "Related steroids, labelled standards and metabolite measurements can be associated with aldosterone without being interchangeable with it.", "layers": [ { "id": "structure-and-identifiers", "name": "Structure and identifiers", "description": "Anchors the entry to a verified molecular structure and identifier record.", "findings": [ { "id": "structure-specific-recognition", "name": "Structure-specific recognition", "description": "Record the structure and stereochemistry that establish aldosterone identity, together with the evidence linking identifiers to that structure.", "questions": [ { "text": "Which verified structure and stereochemical specification define aldosterone for this entry?", "kind": "definition", "id": "structure-specific-recognition-q01" }, { "text": "Which authoritative records support its synonyms, CAS number, PubChem CID and any applicable EC identifier?", "kind": "provenance", "id": "structure-specific-recognition-q02" } ] } ] }, { "id": "parent-and-related-entities", "name": "Parent and related entities", "description": "Separates aldosterone from related steroids, isotopologues and chemically transformed forms.", "findings": [ { "id": "aldosterone-identity-boundary", "name": "Aldosterone identity boundary", "description": "Specify whether a record concerns the unlabelled parent, an isotope-labelled material, a conjugate or a derivative.", "questions": [ { "text": "Does the material contain parent aldosterone, isotope-labelled aldosterone or a chemically distinct conjugate or derivative?", "kind": "boundary", "id": "aldosterone-identity-boundary-q01" }, { "text": "What structural or analytical evidence distinguishes it from corticosterone, cortisol and other relevant steroid interferents?", "kind": "measurement", "id": "aldosterone-identity-boundary-q02" } ] } ] } ] }, { "id": "aldosterone-material-fitness", "name": "Aldosterone material fitness", "description": "Describes the composition and condition of an aldosterone preparation.", "rationale": "Knowing the compound name does not establish the concentration, stability or suitability of a particular lot or solution.", "layers": [ { "id": "preparation-composition", "name": "Preparation composition", "description": "Records aldosterone content, solvent or carrier, and impurities at preparation level.", "findings": [ { "id": "aldosterone-content-assignment", "name": "Aldosterone content assignment", "description": "Distinguish stated purity from assigned aldosterone content and document the basis for either quantity.", "questions": [ { "text": "What aldosterone content is assigned to this preparation, in which units, by which method and with what uncertainty?", "kind": "measurement", "id": "aldosterone-content-assignment-q01" }, { "text": "Which lot certificate identifies the solvent or carrier, water or residual solvent content, and relevant steroid impurities?", "kind": "provenance", "id": "aldosterone-content-assignment-q02" } ] } ] }, { "id": "physical-state-and-stability", "name": "Physical state and stability", "description": "Connects physical properties and storage history to the usability of neat and dissolved aldosterone.", "findings": [ { "id": "preparation-stability-evidence", "name": "Preparation stability evidence", "description": "Record supported solubility, thermal behaviour and stability limits for the specific preparation.", "questions": [ { "text": "What evidence establishes aldosterone solubility and thermal behaviour under the conditions relevant to this preparation?", "kind": "measurement", "id": "preparation-stability-evidence-q01" }, { "text": "Which documented storage conditions, solution lifetime and excursion criteria determine whether the preparation can still be used?", "kind": "action", "id": "preparation-stability-evidence-q02" } ] } ] } ] }, { "id": "aldosterone-biological-context", "name": "Aldosterone biological context", "description": "Records the biological relationships needed to interpret the presence and activity of aldosterone.", "rationale": "Aldosterone's biological meaning depends on production, regulation, target context and transformation rather than concentration alone.", "layers": [ { "id": "production-and-regulation", "name": "Production and regulation", "description": "Links endogenous aldosterone to producing tissues, biosynthetic steps and regulatory conditions.", "findings": [ { "id": "endogenous-origin-and-control", "name": "Endogenous origin and control", "description": "Capture sourced relationships between aldosterone production, adrenal context, regulatory signals and species.", "questions": [ { "text": "Which tissues and biosynthetic steps are established sources of aldosterone in the species being modelled?", "kind": "provenance", "id": "endogenous-origin-and-control-q01" }, { "text": "How are angiotensin signalling, potassium status and other supported regulatory inputs related to production in the recorded context?", "kind": "definition", "id": "endogenous-origin-and-control-q02" } ] } ] }, { "id": "targets-and-transformations", "name": "Targets and transformations", "description": "Separates molecular action from downstream physiological outcomes and metabolic products.", "findings": [ { "id": "context-dependent-aldosterone-action", "name": "Context-dependent aldosterone action", "description": "Record evidence for receptor-mediated activity and transformation without treating receptor binding as proof of an organism-level outcome.", "questions": [ { "text": "Which molecular targets and response measurements support an aldosterone effect in the specified tissue and experimental conditions?", "kind": "measurement", "id": "context-dependent-aldosterone-action-q01" }, { "text": "Which metabolites or conjugates require separate records, and how are their measurements related to parent aldosterone?", "kind": "boundary", "id": "context-dependent-aldosterone-action-q02" } ] } ] } ] }, { "id": "aldosterone-measurement-and-use", "name": "Aldosterone measurement and use", "description": "Determines what an aldosterone result or preparation supports an agent in doing.", "rationale": "Method selectivity, specimen context and preparation-specific restrictions constrain valid comparison, interpretation and handling.", "layers": [ { "id": "analyte-definition-and-assay", "name": "Analyte definition and assay", "description": "Establishes what an assay measures and the conditions under which results are comparable.", "findings": [ { "id": "aldosterone-result-comparability", "name": "Aldosterone result comparability", "description": "Record specimen matrix, collection context, analytical selectivity and whether processing changes the measured analyte pool.", "questions": [ { "text": "Does the method quantify unconjugated aldosterone or a quantity obtained after hydrolysis, and how are cross-reactivity, recovery and quantification limits established?", "kind": "measurement", "id": "aldosterone-result-comparability-q01" }, { "text": "Which collection conditions, including timing, posture, medication exposure and sodium or potassium context, must accompany a result before comparison or interpretation?", "kind": "boundary", "id": "aldosterone-result-comparability-q02" } ] } ] }, { "id": "handling-and-use-eligibility", "name": "Handling and use eligibility", "description": "Connects actual preparation hazards and documented quality to an intended task.", "findings": [ { "id": "preparation-specific-use-decision", "name": "Preparation-specific use decision", "description": "Base handling and suitability decisions on the aldosterone preparation's documentation, including solvent hazards and certified purpose.", "questions": [ { "text": "Which current safety documentation and jurisdiction-specific records establish the hazards and any exposure limits applicable to this preparation?", "kind": "provenance", "id": "preparation-specific-use-decision-q01" }, { "text": "Does the lot's documented grade, traceability and stability support the proposed calibration, laboratory research or other specified use?", "kind": "action", "id": "preparation-specific-use-decision-q02" } ] } ] } ] }, { "id": "evidence-and-external-alignment", "name": "Evidence and external alignment", "description": "What the world already says about this thing, gathered so the model can be checked against it.", "rationale": "A model that cannot be lined up against existing standards, identifiers and practice cannot be adopted by anyone who already uses them.", "layers": [ { "id": "reported-evidence", "name": "Reported evidence", "description": "Findings from the breadth pass, kept separate from the structural claims.", "findings": [ { "id": "evidence-confidence-notes", "name": "Check these first", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "This is recall-based information; no sources were consulted.", "Verify clinical reference intervals and diagnostic thresholds against the specific assay and collection protocol.", "Confirm physical constants, purity specifications and hazard classifications for the specific laboratory material; physiological effects do not establish a reagent's GHS classification." ], "questions": [ { "id": "evidence-confidence-notes-q01", "text": "Which of these check these first hold for the sense of aldosterone this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-identifiers", "name": "Identifiers and schemes", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "scheme": "CAS Registry Number", "value_or_pattern": "52-39-1", "note": "Identifies aldosterone; labelled derivatives and related compounds have separate identities." }, { "scheme": "Molecular formula", "value_or_pattern": "C21H28O5", "note": "Describes elemental composition but does not uniquely identify stereochemistry or distinguish isomers." } ], "questions": [ { "id": "evidence-identifiers-q01", "text": "Which of these identifiers and schemes hold for the sense of aldosterone this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-real-world-use", "name": "Real-world use", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Measurement in blood and urine to investigate disorders of aldosterone production.", "Interpretation alongside renin in screening for primary aldosteronism.", "Research on mineralocorticoid receptors, electrolyte transport and cardiovascular physiology.", "Use as an analytical reference substance for assay calibration." ], "questions": [ { "id": "evidence-real-world-use-q01", "text": "Which of these real-world use hold for the sense of aldosterone this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-measurements", "name": "Typical measurements", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "quantity": "Molar mass", "typical_range": "360.44", "unit": "g/mol" }, { "quantity": "Plasma or serum aldosterone concentration", "typical_range": "Reference intervals depend on assay, posture, collection time, sodium intake and medications.", "unit": "pmol/L or ng/dL" }, { "quantity": "Urinary aldosterone excretion", "typical_range": "Reference intervals depend on assay, sodium intake and completeness of collection.", "unit": "µg/24 h or nmol/24 h" } ], "questions": [ { "id": "evidence-measurements-q01", "text": "Which of these typical measurements hold for the sense of aldosterone this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-failure-modes-and-hazards", "name": "Failure modes and hazards", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Inappropriate excess can cause hypertension, potassium depletion and metabolic alkalosis.", "Deficiency or impaired mineralocorticoid action can cause salt wasting, low blood pressure, hyperkalemia and metabolic acidosis.", "Persistent inappropriate mineralocorticoid receptor activation can contribute to cardiovascular and renal injury.", "Assay interference and unaccounted effects of medications, potassium status, sodium intake or posture can mislead interpretation." ], "questions": [ { "id": "evidence-failure-modes-and-hazards-q01", "text": "Which of these failure modes and hazards hold for the sense of aldosterone this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-regional-variation", "name": "Regional variation", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Laboratories use different concentration units, analytical methods and reference intervals." ], "questions": [ { "id": "evidence-regional-variation-q01", "text": "Which of these regional variation hold for the sense of aldosterone this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-neighbours", "name": "Neighbouring kinds and how to tell them apart", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "name": "cortisol", "difference": "Cortisol is primarily a glucocorticoid; aldosterone is primarily a mineralocorticoid." }, { "name": "corticosterone", "difference": "Corticosterone is a distinct adrenal steroid and biosynthetic precursor; aldosterone has an aldehyde group at carbon 18." }, { "name": "renin", "difference": "Renin is a protein enzyme that initiates the renin-angiotensin cascade; aldosterone is a steroid hormone whose secretion is stimulated downstream." }, { "name": "fludrocortisone", "difference": "Fludrocortisone is a synthetic corticosteroid used for its mineralocorticoid activity; aldosterone is an endogenous hormone." }, { "name": "primary aldosteronism", "difference": "Primary aldosteronism is a disorder of inappropriate adrenal aldosterone production, not the hormone itself." } ], "questions": [ { "id": "evidence-neighbours-q01", "text": "Which of these neighbouring kinds and how to tell them apart hold for the sense of aldosterone this model covers, and on what evidence?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Which authoritative chemical records reconcile aldosterone identifiers, stereochemical representations and any solution-dependent structural forms?", "Which measured physical constants and stability limits are supported for neat aldosterone and commonly used stock solvents, and where are data absent or conflicting?", "Which assay methods distinguish parent aldosterone from relevant steroid interferents and conjugate-derived measurements with sufficient evidence for comparison?", "Which biological and specimen-collection variables are essential for each intended interpretation, and which remain method- or species-dependent?", "Which hazard classifications, exposure limits and use restrictions are documented for aldosterone itself versus specific commercial preparations in the applicable jurisdictions?" ], "statistics": { "bundles": 5, "layers": 9, "findings": 15, "questions": 23 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "chemical substance or material", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a aldosterone, record what state it is in, and decide what may be done with it.", "whatItIs": "Enable an AI agent to recognise aldosterone, assess the identity and fitness of a material or measurement, and determine which handling, analytical or biological interpretations are justified.", "characteristics": { "substance": "material", "origin": "natural", "agency": "inert", "mobility": "varies" }, "whatYouCanDoWithIt": [ "observed and measured", "consumed or used up" ], "distinguishingFeatures": [ "Described in 61 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a aldosterone, and on what evidence are they told apart?" ], "whatItIsMadeOf": "matter you can touch", "physicalCharacter": [ "Mobility varies between examples.", "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state", "use it up, and then need more of it" ], "howItIsRecognised": [ "Not recognisable by sight in any reliable way. Appearance varies with grade, form and additives; identification is by label, by documentation, or by assay." ], "relatedModels": [], "standing": "Described in 61 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one aldosterone from another, and a aldosterone from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a aldosterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a aldosterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a aldosterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a aldosterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a aldosterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a aldosterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a aldosterone sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a aldosterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a aldosterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a aldosterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a aldosterone from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a aldosterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a aldosterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a aldosterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "form-and-composition", "name": "Form, composition and condition", "description": "What a aldosterone is made of, what shape and size it takes, and what state it is in.", "rationale": "A physical thing can be measured, and a model that cannot record its measurements cannot support any decision that depends on them.", "layers": [ { "id": "form-and-dimensions", "name": "Form and dimensions", "description": "Shape, size, mass and the ranges these take across examples.", "findings": [ { "id": "measurable-dimensions", "name": "Measurable dimensions and their units", "description": "The quantities worth recording and the units they are recorded in.", "questions": [ { "id": "measurable-dimensions-q01", "text": "What identifies and describes the dimensions of a aldosterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "measurable-dimensions-q02", "text": "Who or what asserted this about the dimensions of a aldosterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "measurable-dimensions-q03", "text": "What may an agent decide or do once the dimensions of a aldosterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "material-and-composition", "name": "Material and composition", "description": "Materials, parts and how they are put together.", "findings": [ { "id": "parts-and-materials", "name": "Parts and materials", "description": "What a aldosterone is built from and which parts are replaceable.", "questions": [ { "id": "parts-and-materials-q01", "text": "What identifies and describes the composition of a aldosterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "parts-and-materials-q02", "text": "Who or what asserted this about the composition of a aldosterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "parts-and-materials-q03", "text": "What may an agent decide or do once the composition of a aldosterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "condition-and-integrity", "name": "Condition and integrity", "description": "Wear, damage, health and the difference between working and broken.", "findings": [ { "id": "condition-assessment", "name": "Condition, damage and health", "description": "How the condition of a aldosterone is judged and by whom.", "questions": [ { "id": "condition-assessment-q01", "text": "What identifies and describes the condition of a aldosterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "condition-assessment-q02", "text": "Who or what asserted this about the condition of a aldosterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "condition-assessment-q03", "text": "What may an agent decide or do once the condition of a aldosterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "place-and-movement", "name": "Place and movement", "description": "Where a aldosterone is, how it got there and where it may go (varies).", "rationale": "A thing that can move needs its position recorded with a time, or every later claim about it is about a place it has left.", "layers": [ { "id": "location-and-placement", "name": "Location and placement", "description": "Position, containment and the reference frame the position is given in.", "findings": [ { "id": "position-and-frame", "name": "Position, container and reference frame", "description": "Where a aldosterone is, and what that position is measured against.", "questions": [ { "id": "position-and-frame-q01", "text": "What identifies and describes the location of a aldosterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "position-and-frame-q02", "text": "Who or what asserted this about the location of a aldosterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "position-and-frame-q03", "text": "What may an agent decide or do once the location of a aldosterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "movement-and-transfer", "name": "Movement and transfer", "description": "How a aldosterone is carried, installed or relocated.", "findings": [ { "id": "movement-events", "name": "Movement events and constraints", "description": "What counts as a movement, what records it and what limits it.", "questions": [ { "id": "movement-events-q01", "text": "What identifies and describes the movement of a aldosterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "movement-events-q02", "text": "Who or what asserted this about the movement of a aldosterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "movement-events-q03", "text": "What may an agent decide or do once the movement of a aldosterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a aldosterone passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a aldosterone between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a aldosterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a aldosterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a aldosterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a aldosterone, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a aldosterone is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a aldosterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a aldosterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a aldosterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "use-and-operation", "name": "Use and operation", "description": "What can be done with a aldosterone and what it takes to do it.", "rationale": "An agent that can recognise a thing but not act on it has only half a model.", "layers": [ { "id": "intended-use", "name": "Intended use and function", "description": "What a aldosterone is for, and what it is used for anyway.", "findings": [ { "id": "function-and-purpose", "name": "Function, purpose and misuse", "description": "The function a aldosterone performs and the uses that fall outside it.", "questions": [ { "id": "function-and-purpose-q01", "text": "What identifies and describes the use of a aldosterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "function-and-purpose-q02", "text": "Who or what asserted this about the use of a aldosterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "function-and-purpose-q03", "text": "What may an agent decide or do once the use of a aldosterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "handling-and-procedure", "name": "Handling and procedure", "description": "The steps, skills and tools involved in using a aldosterone.", "findings": [ { "id": "procedures-and-skills", "name": "Procedures, skills and required tools", "description": "What an agent needs before it can act on a aldosterone at all.", "questions": [ { "id": "procedures-and-skills-q01", "text": "What identifies and describes handling a aldosterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "procedures-and-skills-q02", "text": "Who or what asserted this about handling a aldosterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "procedures-and-skills-q03", "text": "What may an agent decide or do once handling a aldosterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "supply-and-consumption", "name": "Supply and consumption", "description": "Quantities, rates and what running out means.", "findings": [ { "id": "consumption-and-stock", "name": "Consumption, stock and replenishment", "description": "How much of a aldosterone there is and how fast it goes.", "questions": [ { "id": "consumption-and-stock-q01", "text": "What identifies and describes the supply of a aldosterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "consumption-and-stock-q02", "text": "Who or what asserted this about the supply of a aldosterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "consumption-and-stock-q03", "text": "What may an agent decide or do once the supply of a aldosterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "composition-and-identity", "name": "Composition, grade and chemical identity", "description": "What aldosterone is made of and how pure the thing in hand is.", "rationale": "Grade decides what a substance may be used for, so a model that records only the name cannot support any decision about use.", "layers": [ { "id": "chemical-identity", "name": "Chemical identity", "description": "Formula, structure and the registry numbers that name it unambiguously.", "findings": [ { "id": "identity-record", "name": "Identity and registry numbers", "description": "What identifies this substance across suppliers and regulators.", "questions": [ { "id": "identity-record-q01", "text": "What formula, structure and registry identifiers name aldosterone unambiguously?", "kind": "definition" }, { "id": "identity-record-q02", "text": "Which related substances share a name in common use but not an identifier?", "kind": "boundary" } ] } ] }, { "id": "grade-and-impurities", "name": "Grade, purity and impurities", "description": "The specification a batch meets and what else is in it.", "findings": [ { "id": "specification", "name": "Specification and assay", "description": "How purity is stated and measured, and which impurities matter.", "questions": [ { "id": "specification-q01", "text": "What grades of aldosterone exist, how is purity assayed, and which impurities are limited?", "kind": "measurement" }, { "id": "specification-q02", "text": "Which use requires which grade, and what happens when a lower grade is substituted?", "kind": "action" } ] } ] } ] }, { "id": "properties-and-behaviour", "name": "Properties and behaviour", "description": "How aldosterone behaves under conditions an agent can measure or change.", "rationale": "Physical constants are the part of a substance model that transfers between contexts, and each needs its unit and its conditions.", "layers": [ { "id": "physical-constants", "name": "Physical constants", "description": "Values that hold for the pure substance, with their conditions.", "findings": [ { "id": "constants-record", "name": "Constants and conditions", "description": "The quantities worth recording and the state they apply in.", "questions": [ { "id": "constants-record-q01", "text": "What are the defining physical constants of aldosterone, in what units and under what conditions?", "kind": "measurement" }, { "id": "constants-record-q02", "text": "Which of these values change with grade or form rather than being fixed?", "kind": "boundary" } ] } ] }, { "id": "stability-and-reactivity", "name": "Stability and reactivity", "description": "What it reacts with, degrades into, and how it is stored.", "findings": [ { "id": "incompatibilities", "name": "Incompatibilities and degradation", "description": "What must not meet it, and what it becomes over time.", "questions": [ { "id": "incompatibilities-q01", "text": "What is aldosterone incompatible with, and what does it degrade into under storage?", "kind": "definition" }, { "id": "incompatibilities-q02", "text": "What storage and handling does that require, and who is competent to do it?", "kind": "action" } ] } ] } ] }, { "id": "hazard-and-regulation", "name": "Hazard classification and regulation", "description": "How aldosterone can harm, and what the law says about holding and moving it.", "rationale": "A substance model without its hazard class and its regulatory identity is unusable in exactly the situations that matter.", "layers": [ { "id": "hazard-class", "name": "Hazard classification", "description": "Classified hazards, exposure limits and protective measures.", "findings": [ { "id": "classified-hazards", "name": "Classified hazards and limits", "description": "The classification, the scheme it belongs to, and the limits set.", "questions": [ { "id": "classified-hazards-q01", "text": "How is aldosterone classified for hazard, under which scheme, and what exposure limits apply?", "kind": "definition" }, { "id": "classified-hazards-q02", "text": "What protection does handling require, and what must an agent refuse to do without it?", "kind": "action" } ] } ] }, { "id": "regulatory-identity", "name": "Regulatory identity and control", "description": "Registration, restriction and transport rules by jurisdiction.", "findings": [ { "id": "controls", "name": "Controls and jurisdiction", "description": "Where it is restricted and what the restriction attaches to.", "questions": [ { "id": "controls-q01", "text": "Which registrations, restrictions or transport rules cover aldosterone, and where?", "kind": "provenance" }, { "id": "controls-q02", "text": "Does the control attach to the substance, its concentration, or its intended use?", "kind": "boundary" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a aldosterone came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a aldosterone and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a aldosterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a aldosterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a aldosterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a aldosterone is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a aldosterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a aldosterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a aldosterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 9, "layers": 20, "findings": 22, "questions": 60 } } } }