{
    "model": {
        "rank": 6031,
        "code": "thing-q188261",
        "model_id": "vr.tr.purine",
        "name": "purine",
        "purpose": "Enable an AI agent to recognise parent purine, assess the identity and condition of a purine-containing material, and determine which handling, analytical or chemical actions are justified by available evidence.",
        "family": "Thing Registry",
        "category": "Physical world and living systems",
        "status": "research-draft",
        "kind": "thing",
        "plane": "PHY",
        "domain": "PHY.MAT",
        "industry": "",
        "version": "",
        "url": "/models/thing/q188261/",
        "tier": 2,
        "score": 63,
        "payload": {
            "layer": "wikidata",
            "aliases": [],
            "aliasCount": 0,
            "merged": 0,
            "knownIn": 63,
            "facets": null,
            "markers": [],
            "lexicalClass": "",
            "senseRank": null,
            "alsoRegisteredAs": null,
            "source": {
                "dataset": "wikidata",
                "item": "Q188261",
                "url": "https://www.wikidata.org/wiki/Q188261",
                "license": "CC0 1.0"
            }
        },
        "research": {
            "vercy": "1.0-draft",
            "publication": {
                "status": "research-draft",
                "adjudicationStatus": "unreviewed",
                "publishableCanonical": false,
                "generatedAt": "2026-09-07T11:05:50Z",
                "providers": [
                    "Codex",
                    "Grok"
                ],
                "missingProviders": [],
                "pass": 2,
                "cost": {
                    "grok": {
                        "usd": 0.00522852,
                        "turns": 1,
                        "seconds": 74.7,
                        "error": null
                    },
                    "codex": {
                        "seconds": 82.6,
                        "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.3\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a07b88-5598-7a31-94d5-57fe9bf4f41a\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: purine\nRegistry id: vr.tr.purine\nPlane / domain: PHY / PHY.MAT\nRegistry definition: (none recorded)\nNames folded into this entry: (none)\n\nA Vercy mod"
                    }
                }
            },
            "metaModel": {
                "id": "THING-Q188261",
                "registryId": "vr.tr.purine",
                "name": "purine",
                "version": "0.1.0-research.1",
                "entryKind": "thing",
                "family": "Thing Registry",
                "domain": [
                    "PHY.MAT"
                ],
                "status": "research-draft"
            },
            "canonicalUrl": "https://ver.cy/models/thing/q188261/",
            "model": {
                "registry_id": "vr.tr.purine",
                "name": "purine",
                "purpose": "Enable an AI agent to recognise parent purine, assess the identity and condition of a purine-containing material, and determine which handling, analytical or chemical actions are justified by available evidence.",
                "definition": "Purine is the fused pyrimidine-imidazole heterocycle that is the parent scaffold of the nucleobases adenine and guanine and of their nucleosides, nucleotides, and catabolites.",
                "scope_statement": "This model owns purine as the parent chemical entity and the evidence needed to identify and assess its occurrence in a material, while explicitly distinguishing that entity from the broader family of purine derivatives.",
                "in_scope": [
                    "Identity of the parent purine ring system and molecular composition",
                    "Evidence that a material contains parent purine rather than only purine derivatives",
                    "Tautomeric, protonation and physical states under recorded conditions",
                    "Purine content, impurities and changes in a specimen",
                    "Purine-specific analytical, transformation and handling decisions"
                ],
                "out_of_scope": [
                    "Independent models of substituted purines such as adenine and guanine",
                    "Nucleosides, nucleotides and nucleic acids containing purine-derived bases",
                    "Purine biosynthesis, salvage and degradation pathways as biological systems",
                    "Clinical interpretation of dietary purines, uric acid or gout",
                    "Full equipment, container and laboratory procedure models"
                ],
                "distinguishing_features": [
                    "The assigned structure must have the fused six-membered and five-membered ring connectivity of purine, including its four ring nitrogen positions; a formula match alone is insufficient.",
                    "Neutral parent purine has molecular formula C5H4N4; additional amino, oxo, methyl or other substituents identify derivatives rather than the parent entity.",
                    "A single six-membered nitrogen heterocycle is insufficient: pyrimidine lacks purine's fused five-membered ring.",
                    "A covalently attached sugar or sugar-phosphate component identifies a nucleoside or nucleotide rather than free parent purine.",
                    "A result reported as 'total purines' does not establish the presence or amount of parent purine without a method that distinguishes the relevant compounds."
                ],
                "characteristics": [
                    {
                        "name": "Chemical referent",
                        "kind": "category",
                        "unit_or_values": "parent purine | purine derivative | collective purines | unresolved",
                        "why_it_matters": "Prevents family-level labels and biological measurements from being treated as evidence about the parent compound."
                    },
                    {
                        "name": "Structural identity evidence",
                        "kind": "relation",
                        "unit_or_values": "assigned molecular structure linked to analytical observations, reference material or documented supplier identity",
                        "why_it_matters": "Supports recognition through connectivity and composition rather than an ambiguous name."
                    },
                    {
                        "name": "Protonation and tautomer assignment",
                        "kind": "state",
                        "unit_or_values": "assigned form or unresolved mixture, with method, solvent, pH where applicable and temperature",
                        "why_it_matters": "Hydrogen placement and charge affect interpretation of spectra, interactions and chemical behaviour."
                    },
                    {
                        "name": "Physical presentation",
                        "kind": "state",
                        "unit_or_values": "solid | dissolved | suspension | other documented phase; solid form assigned or unresolved",
                        "why_it_matters": "Determines whether sampling, dissolution or solid-state characterisation is needed before use."
                    },
                    {
                        "name": "Parent purine content",
                        "kind": "measurement",
                        "unit_or_values": "mol/L for solutions, or mass fraction or mole fraction with explicit basis and uncertainty",
                        "why_it_matters": "Makes quantities usable while avoiding confusion with total purines or uncalibrated analytical response."
                    },
                    {
                        "name": "Associated chemical species",
                        "kind": "relation",
                        "unit_or_values": "identified derivatives, counterions, solvents, water and impurities, with quantities where established",
                        "why_it_matters": "Distinguishes the purine entity from the complete composition of the material being assessed."
                    },
                    {
                        "name": "Condition history",
                        "kind": "relation",
                        "unit_or_values": "dated exposure and analytical records linked to a specimen or batch",
                        "why_it_matters": "Allows an agent to judge whether earlier identity and content measurements still support the proposed use."
                    },
                    {
                        "name": "Fitness for intended use",
                        "kind": "state",
                        "unit_or_values": "supported | conditional | unsupported | unassessed, against stated acceptance criteria",
                        "why_it_matters": "Connects identity, composition and condition evidence to a specific analytical or chemical action."
                    }
                ],
                "affordances": [
                    "Resolve whether a record denotes parent purine, a derivative or a collective purines measurement.",
                    "Select an analytical comparison that can test parent purine identity against plausible alternatives.",
                    "Calculate a usable quantity from measured parent purine content and its reporting basis.",
                    "Evaluate dissolution or changes in chemical conditions using evidence applicable to the actual material.",
                    "Assess a proposed chemical transformation and link resulting derivatives to their own identities.",
                    "Approve, condition or defer handling and use according to material-specific evidence and the intended operation."
                ]
            },
            "sources": [
                {
                    "id": "iupac-gold-book-purines",
                    "title": "purines (IUPAC Gold Book)",
                    "url": "https://goldbook.iupac.org/terms/view/P04947",
                    "what_it_supports": "Specialist definition of the fused heterocyclic parent and its derivatives.",
                    "url_status": "blocked"
                },
                {
                    "id": "pubchem-purine",
                    "title": "Purine (compound)",
                    "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1044",
                    "what_it_supports": "CAS, molecular formula, identifiers, and physicochemical data for the parent compound.",
                    "url_status": "live"
                },
                {
                    "id": "chebi-purine",
                    "title": "purine (CHEBI:17258)",
                    "url": "https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:17258",
                    "what_it_supports": "Ontology class, tautomer preference, and relationship to nucleobases and nucleotides.",
                    "url_status": "live"
                },
                {
                    "id": "wikidata-purine",
                    "title": "purine (Q47477)",
                    "url": "https://www.wikidata.org/wiki/Q47477",
                    "what_it_supports": "Cross-registry identifiers (CAS, ChEBI, PubChem, InChIKey).",
                    "url_status": "live"
                }
            ],
            "structure": {
                "bundles": [
                    {
                        "id": "parent-purine-identity",
                        "name": "Parent purine identity",
                        "description": "Establishes what the name purine denotes and whether the chemical evidence supports that interpretation.",
                        "rationale": "Purine can denote a particular parent compound or appear in language referring to a broad chemical family.",
                        "layers": [
                            {
                                "id": "referent-boundary",
                                "name": "Referent boundary",
                                "description": "Separates the parent compound from derivatives and collective measurements.",
                                "findings": [
                                    {
                                        "id": "parent-or-family",
                                        "name": "Parent or family",
                                        "description": "Record the intended referent and the evidence that resolves ambiguous use of the name.",
                                        "questions": [
                                            {
                                                "text": "Does this record mean parent purine, a named derivative or a collection reported as purines?",
                                                "kind": "definition",
                                                "id": "parent-or-family-q01"
                                            },
                                            {
                                                "text": "Which original label, structure or analytical report establishes that interpretation?",
                                                "kind": "provenance",
                                                "id": "parent-or-family-q02"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "molecular-recognition",
                                "name": "Molecular recognition",
                                "description": "Tests the parent ring connectivity and absence of derivative-defining substitutions.",
                                "findings": [
                                    {
                                        "id": "parent-structure-evidence",
                                        "name": "Parent structure evidence",
                                        "description": "Record evidence for the purine skeleton and distinguish a supported assignment from a name or formula match.",
                                        "questions": [
                                            {
                                                "text": "What evidence supports the fused ring connectivity and nitrogen positions of parent purine?",
                                                "kind": "measurement",
                                                "id": "parent-structure-evidence-q01"
                                            },
                                            {
                                                "text": "Does the assigned structure contain an added substituent or covalently attached sugar that places it outside parent purine?",
                                                "kind": "boundary",
                                                "id": "parent-structure-evidence-q02"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "purine-material-composition",
                        "name": "Purine material composition",
                        "description": "Connects the chemical identity to the composition and measured content of a particular material.",
                        "rationale": "A purine-labelled specimen may contain solvents, impurities or derivatives that change what its measured quantity means.",
                        "layers": [
                            {
                                "id": "specimen-assignment",
                                "name": "Specimen assignment",
                                "description": "Connects identity evidence to the actual batch, aliquot or preparation being used.",
                                "findings": [
                                    {
                                        "id": "identity-evidence-transfer",
                                        "name": "Identity evidence transfer",
                                        "description": "Record how the material under consideration is linked to the purine identity evidence.",
                                        "questions": [
                                            {
                                                "text": "Which batch or aliquot was examined to establish parent purine identity?",
                                                "kind": "provenance",
                                                "id": "identity-evidence-transfer-q01"
                                            },
                                            {
                                                "text": "What preparation or mixing steps occurred between that examination and the material now proposed for use?",
                                                "kind": "provenance",
                                                "id": "identity-evidence-transfer-q02"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "content-and-co-components",
                                "name": "Content and co-components",
                                "description": "Distinguishes parent purine quantity from total material mass and other analytical signals.",
                                "findings": [
                                    {
                                        "id": "specific-purine-assay",
                                        "name": "Specific purine assay",
                                        "description": "Record parent purine content with its measurement basis and relevant chemical interferences.",
                                        "questions": [
                                            {
                                                "text": "What parent purine content was measured, on what basis and with what uncertainty?",
                                                "kind": "measurement",
                                                "id": "specific-purine-assay-q01"
                                            },
                                            {
                                                "text": "Which derivatives or other components could contribute to the reported signal, and how were they distinguished?",
                                                "kind": "measurement",
                                                "id": "specific-purine-assay-q02"
                                            },
                                            {
                                                "text": "Does the reported purity describe parent purine mass fraction, chromatographic area fraction or another explicitly defined quantity?",
                                                "kind": "definition",
                                                "id": "specific-purine-assay-q03"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "purine-form-and-environment",
                        "name": "Purine form and environment",
                        "description": "Records the chemical and physical forms relevant to interpreting or using purine under specified conditions.",
                        "rationale": "A parent identity alone does not settle charge, hydrogen placement, dissolution state or solid form.",
                        "layers": [
                            {
                                "id": "protonation-and-tautomerism",
                                "name": "Protonation and tautomerism",
                                "description": "Tracks supported assignments of charge and mobile hydrogen positions without assuming one form applies universally.",
                                "findings": [
                                    {
                                        "id": "condition-dependent-form",
                                        "name": "Condition-dependent form",
                                        "description": "Record any assigned protonation or tautomeric state together with the conditions and evidence supporting it.",
                                        "questions": [
                                            {
                                                "text": "Which protonation or tautomeric form is supported, or is the assignment unresolved?",
                                                "kind": "definition",
                                                "id": "condition-dependent-form-q01"
                                            },
                                            {
                                                "text": "Under which solvent, temperature and acid-base conditions was that assignment established?",
                                                "kind": "measurement",
                                                "id": "condition-dependent-form-q02"
                                            },
                                            {
                                                "text": "Is that assignment applicable under the conditions of the proposed action?",
                                                "kind": "action",
                                                "id": "condition-dependent-form-q03"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "phase-and-dissolution",
                                "name": "Phase and dissolution",
                                "description": "Establishes whether purine is present in a solid phase, solution or a mixture of phases.",
                                "findings": [
                                    {
                                        "id": "available-purine-phase",
                                        "name": "Available purine phase",
                                        "description": "Record the observed physical presentation and whether the intended quantity is actually dissolved or otherwise accessible.",
                                        "questions": [
                                            {
                                                "text": "Is the purine fully dissolved, suspended or present as a characterised or uncharacterised solid?",
                                                "kind": "measurement",
                                                "id": "available-purine-phase-q01"
                                            },
                                            {
                                                "text": "What evidence under the intended solvent, temperature and concentration supports complete dissolution or predicts precipitation?",
                                                "kind": "action",
                                                "id": "available-purine-phase-q02"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "purine-change-and-products",
                        "name": "Purine change and products",
                        "description": "Distinguishes changes in form from chemical conversion and tracks the evidence for resulting identities.",
                        "rationale": "An agent must know when a material still represents parent purine and when a transformation has produced another chemical entity.",
                        "layers": [
                            {
                                "id": "condition-change",
                                "name": "Condition change",
                                "description": "Assesses whether exposure or storage has changed parent purine content or introduced additional species.",
                                "findings": [
                                    {
                                        "id": "retained-parent-identity",
                                        "name": "Retained parent identity",
                                        "description": "Record observed change relative to an earlier characterisation without presuming a degradation mechanism.",
                                        "questions": [
                                            {
                                                "text": "Do measurements after storage or exposure still support the earlier parent purine identity and content?",
                                                "kind": "measurement",
                                                "id": "retained-parent-identity-q01"
                                            },
                                            {
                                                "text": "Which recorded exposures are relevant to investigating any newly observed species or loss of parent purine?",
                                                "kind": "provenance",
                                                "id": "retained-parent-identity-q02"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "chemical-conversion",
                                "name": "Chemical conversion",
                                "description": "Connects proposed reactions and observed products to the boundary of the parent purine model.",
                                "findings": [
                                    {
                                        "id": "transformation-and-identity-boundary",
                                        "name": "Transformation and identity boundary",
                                        "description": "Record the intended structural change, supporting reaction evidence and the resulting chemical identity.",
                                        "questions": [
                                            {
                                                "text": "Which atom or bond change is intended, and what evidence supports that transformation for parent purine under the proposed conditions?",
                                                "kind": "action",
                                                "id": "transformation-and-identity-boundary-q01"
                                            },
                                            {
                                                "text": "Does the observed change represent protonation or tautomerism, or does it produce a distinct derivative or decomposition product?",
                                                "kind": "boundary",
                                                "id": "transformation-and-identity-boundary-q02"
                                            },
                                            {
                                                "text": "What analysis distinguishes remaining parent purine from the proposed products?",
                                                "kind": "measurement",
                                                "id": "transformation-and-identity-boundary-q03"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "purine-use-decisions",
                        "name": "Purine use decisions",
                        "description": "Connects the actual purine material and proposed operation to evidence-based acceptance and handling decisions.",
                        "rationale": "Neither a family-level biological association nor an unverified parent-compound label is enough to justify a laboratory action.",
                        "layers": [
                            {
                                "id": "fitness-for-operation",
                                "name": "Fitness for operation",
                                "description": "Assesses whether the material meets the requirements of a particular use as parent purine.",
                                "findings": [
                                    {
                                        "id": "operation-specific-acceptance",
                                        "name": "Operation-specific acceptance",
                                        "description": "Record the required identity confidence, content and impurity limits for the intended operation.",
                                        "questions": [
                                            {
                                                "text": "Does the intended operation require parent purine specifically, and what identity, content and impurity criteria apply?",
                                                "kind": "action",
                                                "id": "operation-specific-acceptance-q01"
                                            },
                                            {
                                                "text": "Which available measurements satisfy those criteria, and which unresolved issue requires further analysis before use?",
                                                "kind": "action",
                                                "id": "operation-specific-acceptance-q02"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "handling-evidence",
                                "name": "Handling evidence",
                                "description": "Matches handling information to parent purine in the actual formulation and operation.",
                                "findings": [
                                    {
                                        "id": "applicable-handling-basis",
                                        "name": "Applicable handling basis",
                                        "description": "Record an applicable handling basis without transferring claims from dietary purines or unrelated derivatives.",
                                        "questions": [
                                            {
                                                "text": "Which safety and compatibility information explicitly applies to parent purine and this material's formulation?",
                                                "kind": "provenance",
                                                "id": "applicable-handling-basis-q01"
                                            },
                                            {
                                                "text": "Given its physical form, co-components and proposed operation, which handling and disposal measures are supported by that information?",
                                                "kind": "action",
                                                "id": "applicable-handling-basis-q02"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "evidence-and-external-alignment",
                        "name": "Evidence and external alignment",
                        "description": "What the world already says about this thing, gathered so the model can be checked against it.",
                        "rationale": "A model that cannot be lined up against existing standards, identifiers and practice cannot be adopted by anyone who already uses them.",
                        "layers": [
                            {
                                "id": "reported-evidence",
                                "name": "Reported evidence",
                                "description": "Findings from the breadth pass, kept separate from the structural claims.",
                                "findings": [
                                    {
                                        "id": "evidence-kinds",
                                        "name": "Kinds and varieties",
                                        "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.",
                                        "evidence": [
                                            "parent heterocycle (purine, C5H4N4)",
                                            "nucleobases (adenine, guanine, hypoxanthine, xanthine)",
                                            "nucleosides (adenosine, guanosine, inosine)",
                                            "nucleotides and cofactors (AMP, ATP, GTP, NAD, FAD, coenzyme A)",
                                            "uric acid and urate (human end-product of purine catabolism)",
                                            "methylxanthine alkaloids (caffeine, theophylline, theobromine)",
                                            "dietary purines in food",
                                            "synthetic purine analogues used as drugs (e.g. 6-mercaptopurine, allopurinol, aciclovir)"
                                        ],
                                        "questions": [
                                            {
                                                "id": "evidence-kinds-q01",
                                                "text": "Which of these kinds and varieties hold for the sense of purine this model covers, and on what evidence?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    },
                                    {
                                        "id": "evidence-identifiers",
                                        "name": "Identifiers and schemes",
                                        "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.",
                                        "evidence": [
                                            {
                                                "scheme": "CAS Registry Number",
                                                "value_or_pattern": "120-73-0",
                                                "note": "Parent heterocycle purine."
                                            },
                                            {
                                                "scheme": "PubChem CID",
                                                "value_or_pattern": "1044",
                                                "note": "Parent compound record."
                                            },
                                            {
                                                "scheme": "ChEBI",
                                                "value_or_pattern": "CHEBI:17258",
                                                "note": "Preferred 7H/9H tautomer class for the parent."
                                            },
                                            {
                                                "scheme": "Wikidata",
                                                "value_or_pattern": "Q47477",
                                                "note": "Item for the chemical compound purine."
                                            },
                                            {
                                                "scheme": "InChIKey",
                                                "value_or_pattern": "KDCGOANMDULRCW-UHFFFAOYSA-N",
                                                "note": "Standard InChIKey for unsubstituted purine."
                                            },
                                            {
                                                "scheme": "UNII",
                                                "value_or_pattern": "W97O5H3Wmk",
                                                "note": "FDA Unique Ingredient Identifier; confirm case in FDA SRS."
                                            }
                                        ],
                                        "questions": [
                                            {
                                                "id": "evidence-identifiers-q01",
                                                "text": "Which of these identifiers and schemes hold for the sense of purine this model covers, and on what evidence?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    },
                                    {
                                        "id": "evidence-standards-and-regulation",
                                        "name": "Standards and regulation",
                                        "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.",
                                        "evidence": [
                                            "IUPAC recommendations on fused heterocyclic nomenclature (purine numbering, 7H/9H tautomerism).",
                                            "Pharmacopoeial monographs for individual purine drugs and methylxanthines (USP, Ph. Eur., JP) rather than for the parent heterocycle.",
                                            "Clinical practice guidelines on hyperuricaemia and gout that treat dietary purine load and serum urate as managed quantities (ACR, EULAR)."
                                        ],
                                        "questions": [
                                            {
                                                "id": "evidence-standards-and-regulation-q01",
                                                "text": "Which of these standards and regulation hold for the sense of purine this model covers, and on what evidence?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    },
                                    {
                                        "id": "evidence-real-world-use",
                                        "name": "Real-world use",
                                        "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.",
                                        "evidence": [
                                            "DNA and RNA nucleobases adenine and guanine, and the corresponding nucleosides and nucleotides.",
                                            "Cellular energy and signalling cofactors (ATP, GTP, cAMP, NAD, FAD).",
                                            "Dietary constituents whose intake is managed in gout and urate-kidney-stone care.",
                                            "Plant alkaloids in coffee, tea, cocoa, and related drugs (caffeine, theophylline, theobromine).",
                                            "Antimetabolite, antiviral, and urate-lowering medicines built on the purine scaffold."
                                        ],
                                        "questions": [
                                            {
                                                "id": "evidence-real-world-use-q01",
                                                "text": "Which of these real-world use hold for the sense of purine this model covers, and on what evidence?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    },
                                    {
                                        "id": "evidence-measurements",
                                        "name": "Typical measurements",
                                        "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.",
                                        "evidence": [
                                            {
                                                "quantity": "molecular mass of parent purine",
                                                "typical_range": "120.11",
                                                "unit": "g mol−1"
                                            },
                                            {
                                                "quantity": "melting point of parent purine",
                                                "typical_range": "214-217",
                                                "unit": "°C"
                                            },
                                            {
                                                "quantity": "dietary purine content of foods",
                                                "typical_range": "about 10-400 (much higher in some organ meats and some seafood)",
                                                "unit": "mg per 100 g edible portion"
                                            },
                                            {
                                                "quantity": "serum urate (clinical proxy of purine end-product in humans)",
                                                "typical_range": "about 200-420 in adults, with laboratory- and sex-specific reference intervals",
                                                "unit": "µmol L−1"
                                            }
                                        ],
                                        "questions": [
                                            {
                                                "id": "evidence-measurements-q01",
                                                "text": "Which of these typical measurements hold for the sense of purine this model covers, and on what evidence?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    },
                                    {
                                        "id": "evidence-failure-modes-and-hazards",
                                        "name": "Failure modes and hazards",
                                        "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.",
                                        "evidence": [
                                            "Excess net purine load or underexcretion of urate causing hyperuricaemia, gouty arthritis, and urate nephrolithiasis.",
                                            "Tumour lysis releasing nucleic-acid purines and precipitating acute uric-acid nephropathy.",
                                            "Cytotoxicity of some purine antimetabolites (bone-marrow suppression, immunosuppression).",
                                            "Acute methylxanthine toxicity (caffeine, theophylline) at high dose.",
                                            "The parent heterocycle itself is not a bulk industrial hazard in ordinary use."
                                        ],
                                        "questions": [
                                            {
                                                "id": "evidence-failure-modes-and-hazards-q01",
                                                "text": "Which of these failure modes and hazards hold for the sense of purine this model covers, and on what evidence?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    },
                                    {
                                        "id": "evidence-regional-variation",
                                        "name": "Regional variation",
                                        "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.",
                                        "evidence": [
                                            "Low-purine diet lists and cut-offs differ by country and by food-composition table, not by a single global food-law definition of \"purine content\".",
                                            "Clinical serum-urate targets and gout-treatment algorithms differ between ACR (US) and EULAR (Europe) practice.",
                                            "Nitrogen-excretion biology differs across taxa (uric acid in humans and uricotelic animals versus allantoin in most other mammals), which changes what \"purine end-product\" means in veterinary versus human settings."
                                        ],
                                        "questions": [
                                            {
                                                "id": "evidence-regional-variation-q01",
                                                "text": "Which of these regional variation hold for the sense of purine this model covers, and on what evidence?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    },
                                    {
                                        "id": "evidence-neighbours",
                                        "name": "Neighbouring kinds and how to tell them apart",
                                        "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.",
                                        "evidence": [
                                            {
                                                "name": "pyrimidine",
                                                "difference": "Pyrimidine is a single six-membered diazine; purine is that ring fused to imidazole. Elemental formula and fused-ring numbering separate them."
                                            },
                                            {
                                                "name": "pteridine",
                                                "difference": "Pteridine is pyrimidine fused to pyrazine (two six-membered rings); purine is pyrimidine fused to imidazole. Ring-size count and ChEBI/IUPAC parent distinguish them."
                                            },
                                            {
                                                "name": "uric acid",
                                                "difference": "Uric acid is a trioxygenated purine catabolite (7,9-dihydro-1H-purine-2,6,8-trione), not the unsubstituted parent; CAS 69-93-2 versus 120-73-0."
                                            },
                                            {
                                                "name": "pyridine",
                                                "difference": "Pyridine is a six-membered monoazine with no fused imidazole and only one nitrogen; mass spectrum and nitrogen count separate it from purine."
                                            }
                                        ],
                                        "questions": [
                                            {
                                                "id": "evidence-neighbours-q01",
                                                "text": "Which of these neighbouring kinds and how to tell them apart hold for the sense of purine this model covers, and on what evidence?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    }
                ]
            },
            "openQuestions": [
                "Does the registry intend purine to denote the parent compound exclusively, or must this entry also resolve references to the chemical family?",
                "Which accessible reference materials and analytical methods provide sufficient discrimination of parent purine from likely derivatives and other interfering compounds?",
                "Which protonation and tautomer assignments are experimentally supported under the conditions relevant to intended uses?",
                "What reliable evidence establishes solubility, solid forms and stability across the intended storage and preparation conditions?",
                "Which authoritative handling information and use-specific acceptance criteria apply to the actual purine materials agents will encounter?"
            ],
            "statistics": {
                "bundles": 6,
                "layers": 11,
                "findings": 18,
                "questions": 31
            }
        },
        "draft": {
            "generator": "vr.draft.v3",
            "status": "draft-generated",
            "researched": false,
            "archetype": "chemical substance or material",
            "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.",
            "facetsInferred": true,
            "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.",
            "purpose": "Give an agent a durable, checkable way to recognise a purine, record what state it is in, and decide what may be done with it.",
            "whatItIs": "Enable an AI agent to recognise parent purine, assess the identity and condition of a purine-containing material, and determine which handling, analytical or chemical actions are justified by available evidence.",
            "characteristics": {
                "substance": "material",
                "origin": "natural",
                "agency": "inert",
                "mobility": "varies"
            },
            "whatYouCanDoWithIt": [
                "observed and measured",
                "consumed or used up"
            ],
            "distinguishingFeatures": [
                "Described in 63 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is."
            ],
            "openQuestionsForResearch": [
                "Which of the bundles below does a real task actually need, and which are ceremony?",
                "What does this thing have that the facets do not capture at all?",
                "Which neighbouring kind is most often confused with a purine, and on what evidence are they told apart?"
            ],
            "whatItIsMadeOf": "matter you can touch",
            "physicalCharacter": [
                "Mobility varies between examples.",
                "Does nothing on its own; everything it does, something else did to it.",
                "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing."
            ],
            "whatCanBeDoneWithIt": [
                "observe it, measure it, record its state",
                "use it up, and then need more of it"
            ],
            "howItIsRecognised": [
                "Not recognisable by sight in any reliable way. Appearance varies with grade, form and additives; identification is by label, by documentation, or by assay."
            ],
            "relatedModels": [],
            "standing": "Described in 63 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is.",
            "structure": {
                "bundles": [
                    {
                        "id": "identity-and-classification",
                        "name": "Identity, naming and classification",
                        "description": "How an agent tells one purine from another, and a purine from things that resemble it.",
                        "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.",
                        "layers": [
                            {
                                "id": "naming-and-identifiers",
                                "name": "Names and identifiers",
                                "description": "The names this thing goes by and the identifiers that survive translation and time.",
                                "findings": [
                                    {
                                        "id": "preferred-name-and-aliases",
                                        "name": "Preferred name, aliases and local names",
                                        "description": "Which name to use, which names mean the same thing, and which merely sound similar.",
                                        "questions": [
                                            {
                                                "id": "preferred-name-and-aliases-q01",
                                                "text": "What identifies and describes the name of a purine, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "preferred-name-and-aliases-q02",
                                                "text": "Who or what asserted this about the name of a purine, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "preferred-name-and-aliases-q03",
                                                "text": "What may an agent decide or do once the name of a purine is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    },
                                    {
                                        "id": "stable-identifiers",
                                        "name": "Stable identifiers and external keys",
                                        "description": "Identifiers that keep pointing at this kind of thing across systems and languages.",
                                        "questions": [
                                            {
                                                "id": "stable-identifiers-q01",
                                                "text": "What identifies and describes an identifier for a purine, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "stable-identifiers-q02",
                                                "text": "Who or what asserted this about an identifier for a purine, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "stable-identifiers-q03",
                                                "text": "What may an agent decide or do once an identifier for a purine is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "classification-and-granularity",
                                "name": "Classification and granularity",
                                "description": "Where a purine sits among kinds, and how finely a task needs to cut it.",
                                "findings": [
                                    {
                                        "id": "kind-and-parents",
                                        "name": "Kind, parents and neighbouring kinds",
                                        "description": "The classes this thing belongs to and the ones it is next to.",
                                        "questions": [
                                            {
                                                "id": "kind-and-parents-q01",
                                                "text": "What identifies and describes the kind of a purine, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "kind-and-parents-q02",
                                                "text": "Who or what asserted this about the kind of a purine, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "kind-and-parents-q03",
                                                "text": "What may an agent decide or do once the kind of a purine is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    },
                                    {
                                        "id": "distinguishing-features",
                                        "name": "Distinguishing features",
                                        "description": "What separates a purine from the things most often confused with it.",
                                        "questions": [
                                            {
                                                "id": "distinguishing-features-q01",
                                                "text": "What identifies and describes what distinguishes a purine, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "distinguishing-features-q02",
                                                "text": "Who or what asserted this about what distinguishes a purine, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "distinguishing-features-q03",
                                                "text": "What may an agent decide or do once what distinguishes a purine is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "form-and-composition",
                        "name": "Form, composition and condition",
                        "description": "What a purine is made of, what shape and size it takes, and what state it is in.",
                        "rationale": "A physical thing can be measured, and a model that cannot record its measurements cannot support any decision that depends on them.",
                        "layers": [
                            {
                                "id": "form-and-dimensions",
                                "name": "Form and dimensions",
                                "description": "Shape, size, mass and the ranges these take across examples.",
                                "findings": [
                                    {
                                        "id": "measurable-dimensions",
                                        "name": "Measurable dimensions and their units",
                                        "description": "The quantities worth recording and the units they are recorded in.",
                                        "questions": [
                                            {
                                                "id": "measurable-dimensions-q01",
                                                "text": "What identifies and describes the dimensions of a purine, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "measurable-dimensions-q02",
                                                "text": "Who or what asserted this about the dimensions of a purine, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "measurable-dimensions-q03",
                                                "text": "What may an agent decide or do once the dimensions of a purine is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "material-and-composition",
                                "name": "Material and composition",
                                "description": "Materials, parts and how they are put together.",
                                "findings": [
                                    {
                                        "id": "parts-and-materials",
                                        "name": "Parts and materials",
                                        "description": "What a purine is built from and which parts are replaceable.",
                                        "questions": [
                                            {
                                                "id": "parts-and-materials-q01",
                                                "text": "What identifies and describes the composition of a purine, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "parts-and-materials-q02",
                                                "text": "Who or what asserted this about the composition of a purine, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "parts-and-materials-q03",
                                                "text": "What may an agent decide or do once the composition of a purine is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "condition-and-integrity",
                                "name": "Condition and integrity",
                                "description": "Wear, damage, health and the difference between working and broken.",
                                "findings": [
                                    {
                                        "id": "condition-assessment",
                                        "name": "Condition, damage and health",
                                        "description": "How the condition of a purine is judged and by whom.",
                                        "questions": [
                                            {
                                                "id": "condition-assessment-q01",
                                                "text": "What identifies and describes the condition of a purine, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "condition-assessment-q02",
                                                "text": "Who or what asserted this about the condition of a purine, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "condition-assessment-q03",
                                                "text": "What may an agent decide or do once the condition of a purine is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "place-and-movement",
                        "name": "Place and movement",
                        "description": "Where a purine is, how it got there and where it may go (varies).",
                        "rationale": "A thing that can move needs its position recorded with a time, or every later claim about it is about a place it has left.",
                        "layers": [
                            {
                                "id": "location-and-placement",
                                "name": "Location and placement",
                                "description": "Position, containment and the reference frame the position is given in.",
                                "findings": [
                                    {
                                        "id": "position-and-frame",
                                        "name": "Position, container and reference frame",
                                        "description": "Where a purine is, and what that position is measured against.",
                                        "questions": [
                                            {
                                                "id": "position-and-frame-q01",
                                                "text": "What identifies and describes the location of a purine, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "position-and-frame-q02",
                                                "text": "Who or what asserted this about the location of a purine, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "position-and-frame-q03",
                                                "text": "What may an agent decide or do once the location of a purine is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "movement-and-transfer",
                                "name": "Movement and transfer",
                                "description": "How a purine is carried, installed or relocated.",
                                "findings": [
                                    {
                                        "id": "movement-events",
                                        "name": "Movement events and constraints",
                                        "description": "What counts as a movement, what records it and what limits it.",
                                        "questions": [
                                            {
                                                "id": "movement-events-q01",
                                                "text": "What identifies and describes the movement of a purine, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "movement-events-q02",
                                                "text": "Who or what asserted this about the movement of a purine, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "movement-events-q03",
                                                "text": "What may an agent decide or do once the movement of a purine is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "state-and-lifecycle",
                        "name": "State and lifecycle",
                        "description": "The states a purine passes through and the events that move it between them.",
                        "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.",
                        "layers": [
                            {
                                "id": "lifecycle-stages",
                                "name": "Lifecycle stages",
                                "description": "From coming into existence to ceasing to be one of these.",
                                "findings": [
                                    {
                                        "id": "stages-and-transitions",
                                        "name": "Stages and transitions",
                                        "description": "The stages worth naming and what moves a purine between them.",
                                        "questions": [
                                            {
                                                "id": "stages-and-transitions-q01",
                                                "text": "What identifies and describes the lifecycle of a purine, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "stages-and-transitions-q02",
                                                "text": "Who or what asserted this about the lifecycle of a purine, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "stages-and-transitions-q03",
                                                "text": "What may an agent decide or do once the lifecycle of a purine is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "observations-and-status",
                                "name": "Observations and current status",
                                "description": "What is observed about a purine, how often and by whom.",
                                "findings": [
                                    {
                                        "id": "observation-record",
                                        "name": "Observation record",
                                        "description": "How an observation of a purine is recorded so that it can be superseded rather than overwritten.",
                                        "questions": [
                                            {
                                                "id": "observation-record-q01",
                                                "text": "What identifies and describes an observation of a purine, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "observation-record-q02",
                                                "text": "Who or what asserted this about an observation of a purine, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "observation-record-q03",
                                                "text": "What may an agent decide or do once an observation of a purine is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "use-and-operation",
                        "name": "Use and operation",
                        "description": "What can be done with a purine and what it takes to do it.",
                        "rationale": "An agent that can recognise a thing but not act on it has only half a model.",
                        "layers": [
                            {
                                "id": "intended-use",
                                "name": "Intended use and function",
                                "description": "What a purine is for, and what it is used for anyway.",
                                "findings": [
                                    {
                                        "id": "function-and-purpose",
                                        "name": "Function, purpose and misuse",
                                        "description": "The function a purine performs and the uses that fall outside it.",
                                        "questions": [
                                            {
                                                "id": "function-and-purpose-q01",
                                                "text": "What identifies and describes the use of a purine, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "function-and-purpose-q02",
                                                "text": "Who or what asserted this about the use of a purine, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "function-and-purpose-q03",
                                                "text": "What may an agent decide or do once the use of a purine is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "handling-and-procedure",
                                "name": "Handling and procedure",
                                "description": "The steps, skills and tools involved in using a purine.",
                                "findings": [
                                    {
                                        "id": "procedures-and-skills",
                                        "name": "Procedures, skills and required tools",
                                        "description": "What an agent needs before it can act on a purine at all.",
                                        "questions": [
                                            {
                                                "id": "procedures-and-skills-q01",
                                                "text": "What identifies and describes handling a purine, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "procedures-and-skills-q02",
                                                "text": "Who or what asserted this about handling a purine, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "procedures-and-skills-q03",
                                                "text": "What may an agent decide or do once handling a purine is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "supply-and-consumption",
                                "name": "Supply and consumption",
                                "description": "Quantities, rates and what running out means.",
                                "findings": [
                                    {
                                        "id": "consumption-and-stock",
                                        "name": "Consumption, stock and replenishment",
                                        "description": "How much of a purine there is and how fast it goes.",
                                        "questions": [
                                            {
                                                "id": "consumption-and-stock-q01",
                                                "text": "What identifies and describes the supply of a purine, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "consumption-and-stock-q02",
                                                "text": "Who or what asserted this about the supply of a purine, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "consumption-and-stock-q03",
                                                "text": "What may an agent decide or do once the supply of a purine is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "composition-and-identity",
                        "name": "Composition, grade and chemical identity",
                        "description": "What purine is made of and how pure the thing in hand is.",
                        "rationale": "Grade decides what a substance may be used for, so a model that records only the name cannot support any decision about use.",
                        "layers": [
                            {
                                "id": "chemical-identity",
                                "name": "Chemical identity",
                                "description": "Formula, structure and the registry numbers that name it unambiguously.",
                                "findings": [
                                    {
                                        "id": "identity-record",
                                        "name": "Identity and registry numbers",
                                        "description": "What identifies this substance across suppliers and regulators.",
                                        "questions": [
                                            {
                                                "id": "identity-record-q01",
                                                "text": "What formula, structure and registry identifiers name purine unambiguously?",
                                                "kind": "definition"
                                            },
                                            {
                                                "id": "identity-record-q02",
                                                "text": "Which related substances share a name in common use but not an identifier?",
                                                "kind": "boundary"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "grade-and-impurities",
                                "name": "Grade, purity and impurities",
                                "description": "The specification a batch meets and what else is in it.",
                                "findings": [
                                    {
                                        "id": "specification",
                                        "name": "Specification and assay",
                                        "description": "How purity is stated and measured, and which impurities matter.",
                                        "questions": [
                                            {
                                                "id": "specification-q01",
                                                "text": "What grades of purine exist, how is purity assayed, and which impurities are limited?",
                                                "kind": "measurement"
                                            },
                                            {
                                                "id": "specification-q02",
                                                "text": "Which use requires which grade, and what happens when a lower grade is substituted?",
                                                "kind": "action"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "properties-and-behaviour",
                        "name": "Properties and behaviour",
                        "description": "How purine behaves under conditions an agent can measure or change.",
                        "rationale": "Physical constants are the part of a substance model that transfers between contexts, and each needs its unit and its conditions.",
                        "layers": [
                            {
                                "id": "physical-constants",
                                "name": "Physical constants",
                                "description": "Values that hold for the pure substance, with their conditions.",
                                "findings": [
                                    {
                                        "id": "constants-record",
                                        "name": "Constants and conditions",
                                        "description": "The quantities worth recording and the state they apply in.",
                                        "questions": [
                                            {
                                                "id": "constants-record-q01",
                                                "text": "What are the defining physical constants of purine, in what units and under what conditions?",
                                                "kind": "measurement"
                                            },
                                            {
                                                "id": "constants-record-q02",
                                                "text": "Which of these values change with grade or form rather than being fixed?",
                                                "kind": "boundary"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "stability-and-reactivity",
                                "name": "Stability and reactivity",
                                "description": "What it reacts with, degrades into, and how it is stored.",
                                "findings": [
                                    {
                                        "id": "incompatibilities",
                                        "name": "Incompatibilities and degradation",
                                        "description": "What must not meet it, and what it becomes over time.",
                                        "questions": [
                                            {
                                                "id": "incompatibilities-q01",
                                                "text": "What is purine incompatible with, and what does it degrade into under storage?",
                                                "kind": "definition"
                                            },
                                            {
                                                "id": "incompatibilities-q02",
                                                "text": "What storage and handling does that require, and who is competent to do it?",
                                                "kind": "action"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "hazard-and-regulation",
                        "name": "Hazard classification and regulation",
                        "description": "How purine can harm, and what the law says about holding and moving it.",
                        "rationale": "A substance model without its hazard class and its regulatory identity is unusable in exactly the situations that matter.",
                        "layers": [
                            {
                                "id": "hazard-class",
                                "name": "Hazard classification",
                                "description": "Classified hazards, exposure limits and protective measures.",
                                "findings": [
                                    {
                                        "id": "classified-hazards",
                                        "name": "Classified hazards and limits",
                                        "description": "The classification, the scheme it belongs to, and the limits set.",
                                        "questions": [
                                            {
                                                "id": "classified-hazards-q01",
                                                "text": "How is purine classified for hazard, under which scheme, and what exposure limits apply?",
                                                "kind": "definition"
                                            },
                                            {
                                                "id": "classified-hazards-q02",
                                                "text": "What protection does handling require, and what must an agent refuse to do without it?",
                                                "kind": "action"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "regulatory-identity",
                                "name": "Regulatory identity and control",
                                "description": "Registration, restriction and transport rules by jurisdiction.",
                                "findings": [
                                    {
                                        "id": "controls",
                                        "name": "Controls and jurisdiction",
                                        "description": "Where it is restricted and what the restriction attaches to.",
                                        "questions": [
                                            {
                                                "id": "controls-q01",
                                                "text": "Which registrations, restrictions or transport rules cover purine, and where?",
                                                "kind": "provenance"
                                            },
                                            {
                                                "id": "controls-q02",
                                                "text": "Does the control attach to the substance, its concentration, or its intended use?",
                                                "kind": "boundary"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "provenance-and-evidence",
                        "name": "Provenance, evidence and time",
                        "description": "Where every claim about a purine came from and when it held.",
                        "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.",
                        "layers": [
                            {
                                "id": "source-and-authority",
                                "name": "Source and authority",
                                "description": "Who said it, on what evidence, and how strongly.",
                                "findings": [
                                    {
                                        "id": "claim-provenance",
                                        "name": "Claim provenance and confidence",
                                        "description": "The authority behind each claim about a purine and how confident it is.",
                                        "questions": [
                                            {
                                                "id": "claim-provenance-q01",
                                                "text": "What identifies and describes a claim about a purine, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "claim-provenance-q02",
                                                "text": "Who or what asserted this about a claim about a purine, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "claim-provenance-q03",
                                                "text": "What may an agent decide or do once a claim about a purine is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "time-and-versions",
                                "name": "Time, versions and supersession",
                                "description": "When a claim was true, when it was learnt, and what replaced it.",
                                "findings": [
                                    {
                                        "id": "validity-and-supersession",
                                        "name": "Validity period and supersession",
                                        "description": "How an old claim about a purine is retired without being erased.",
                                        "questions": [
                                            {
                                                "id": "validity-and-supersession-q01",
                                                "text": "What identifies and describes the validity of a claim about a purine, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "validity-and-supersession-q02",
                                                "text": "Who or what asserted this about the validity of a claim about a purine, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "validity-and-supersession-q03",
                                                "text": "What may an agent decide or do once the validity of a claim about a purine is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    }
                ]
            },
            "statistics": {
                "bundles": 9,
                "layers": 20,
                "findings": 22,
                "questions": 60
            }
        }
    }
}