{ "model": { "rank": 5154, "code": "thing-q190875", "model_id": "vr.tr.cortisol", "name": "cortisol", "purpose": "Enable an AI agent to identify cortisol, assess a material sample or biological measurement in context, and determine what handling, comparison or further investigation is justified.", "family": "Thing Registry", "category": "Physical world and living systems", "status": "research-draft", "kind": "thing", "plane": "PHY", "domain": "PHY.MAT", "industry": "", "version": "", "url": "/models/thing/q190875/", "tier": 2, "score": 69, "payload": { "layer": "wikidata", "aliases": [], "aliasCount": 0, "merged": 0, "knownIn": 69, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q190875", "url": "https://www.wikidata.org/wiki/Q190875", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-09T21:47:16Z", "providers": [ "Codex" ], "breadth": "recalled by Codex without web access - no source was read", "missingProviders": [], "pass": 2, "cost": { "grok": { "seconds": 20.3, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a08822-a340-7590-b4cf-4303521c2041\n--------\nuser\nDescribe what is already known about one registered thing. Answer as JSON only, no prose around it.\n\nThing: cortisol\nSense to describe: (none recorded)\nDomain code: PHY.MAT\nAlso known as: (none)\n\n\nContext for this batch of 1001 things:\n# Batch 005: 1001 regist", "usd": 0, "recall": true }, "codex": { "seconds": 70.7, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a08822-a33a-7763-ae26-ff48f3c396b5\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: cortisol\nRegistry id: vr.tr.cortisol\nPlane / domain: PHY / PHY.MAT\nRegistry definition: (none recorded)\nNames folded into this entry: (none)\n\n\nContex" } } }, "metaModel": { "id": "THING-Q190875", "registryId": "vr.tr.cortisol", "name": "cortisol", "version": "0.1.0-research.1", "entryKind": "thing", "family": "Thing Registry", "domain": [ "PHY.MAT" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q190875/", "model": { "registry_id": "vr.tr.cortisol", "name": "cortisol", "purpose": "Enable an AI agent to identify cortisol, assess a material sample or biological measurement in context, and determine what handling, comparison or further investigation is justified.", "definition": "Cortisol, also called hydrocortisone, is a steroid hormone produced primarily by the adrenal cortex that acts through glucocorticoid receptors to regulate metabolism, immune activity and physiological responses to stress.", "scope_statement": "This model owns cortisol as the chemical substance registered as vr.tr.cortisol in PHY / PHY.MAT, including its identity, material quality, biological occurrence, measurement context and use constraints; it distinguishes the substance from medicinal products, laboratory procedures and clinical diagnoses.", "in_scope": [ "Chemical identity of cortisol, including its relationship to the name hydrocortisone", "Composition, purity, physical form and stability of cortisol material", "Endogenous occurrence, production, transport and conversion relationships", "Cortisol measurements qualified by specimen, timing, method and measured fraction", "Evidence governing material handling, storage and suitability for an intended use" ], "out_of_scope": [ "Finished hydrocortisone medicines, their formulations and prescribing regimens", "Cortisol esters, conjugates, cortisone and other related substances as independent chemical entities", "Adrenal or pituitary disorders and their diagnostic or treatment pathways", "Stress as a psychological experience or a complete physiological response", "Complete assay protocols, laboratory instruments and specimen collection devices", "Whole-organism endocrine regulation beyond relationships needed to interpret cortisol" ], "distinguishing_features": [ "Resolve cortisol and hydrocortisone to the same parent chemical identity while distinguishing a named medicinal product from that substance.", "Require structural agreement, including stereochemistry; a steroid label or molecular formula alone does not establish cortisol identity.", "Distinguish cortisol from cortisone by the chemical state at carbon 11 rather than treating their similar names as synonyms.", "Distinguish unmodified cortisol from hydrocortisone esters and cortisol conjugates even when a product or assay reports an amount as cortisol equivalent.", "Distinguish free cortisol, total cortisol and a specimen-specific excretion result; they are different observables rather than interchangeable cortisol levels." ], "characteristics": [ { "name": "Parent substance identity", "kind": "category", "unit_or_values": "Verified structural representation, stereochemistry and cross-referenced chemical identifiers", "why_it_matters": "Prevents related steroids, derivatives or product names from being mistaken for cortisol." }, { "name": "Material or observation context", "kind": "category", "unit_or_values": "Isolated material; reference standard; solution; biological constituent; reported analytical result", "why_it_matters": "Determines which quality, state and interpretation questions apply." }, { "name": "Purity and content basis", "kind": "measurement", "unit_or_values": "Mass fraction or percentage with method, uncertainty and as-received or corrected basis", "why_it_matters": "Separates actual cortisol content from a supplier label or chromatographic area percentage." }, { "name": "Physical form and medium", "kind": "state", "unit_or_values": "Solid form or dissolved state, solvent or matrix, temperature and relevant solution conditions", "why_it_matters": "Conditions affect preparation, stability and suitability for use." }, { "name": "Measured cortisol quantity", "kind": "measurement", "unit_or_values": "Matrix-appropriate concentration, amount or timed excretion, with explicit units and uncertainty", "why_it_matters": "Prevents comparisons between quantities that represent different measurements." }, { "name": "Measured fraction and analyte specificity", "kind": "category", "unit_or_values": "Free; total; otherwise operationally defined, with cross-reactivity or analyte inclusions stated", "why_it_matters": "Defines what the reported number actually represents." }, { "name": "Specimen and collection interval", "kind": "category", "unit_or_values": "Serum; plasma; saliva; urine; hair; other specified matrix, with collection time or interval", "why_it_matters": "Different specimens and intervals require different interpretation." }, { "name": "Physiological and exposure context", "kind": "relation", "unit_or_values": "Links to sleep and waking times, relevant physiological state, medication exposure and sampling event", "why_it_matters": "Supports contextual interpretation without assigning a diagnosis from cortisol alone." }, { "name": "Binding and conversion relationships", "kind": "relation", "unit_or_values": "Links to binding proteins, free fraction, cortisone and relevant production or conversion processes", "why_it_matters": "Connects measured cortisol to transport and metabolism without equating concentration with production rate." }, { "name": "Storage and stability status", "kind": "state", "unit_or_values": "Documented conditions, elapsed storage, excursions and evidence-supported validity", "why_it_matters": "Determines whether material or a specimen remains suitable for its intended purpose." }, { "name": "Use qualification", "kind": "category", "unit_or_values": "Research material; analytical standard; pharmacopoeial material; other documented grade", "why_it_matters": "Chemical identity alone does not establish fitness for calibration, manufacture or administration." } ], "affordances": [ "Resolve names and identifiers to cortisol while flagging derivatives and finished products.", "Assess whether a cortisol lot or solution meets the documented requirements of an intended laboratory use.", "Normalize compatible measurement units while preserving specimen, fraction and collection interval.", "Determine whether two cortisol observations are comparable and explain missing context.", "Trace an unexpected result to possible collection, stability, method or exposure factors for further investigation.", "Retrieve applicable handling and use requirements from documentation for the actual material." ] }, "sources": [], "structure": { "bundles": [ { "id": "cortisol-identity", "name": "Cortisol identity", "description": "Establish the exact parent substance and resolve nearby chemical and product names.", "rationale": "Cortisol commonly appears under the name hydrocortisone and near chemically distinct derivatives.", "layers": [ { "id": "parent-structure", "name": "Parent structure", "description": "Anchor identity in a verified structure and identifier record.", "findings": [ { "id": "structural-identity-check", "name": "Structural identity check", "description": "Record evidence sufficient to identify cortisol rather than merely a steroid with a matching formula.", "questions": [ { "text": "Which verified structure, stereochemistry and chemical identifiers establish that this entity is cortisol?", "kind": "definition", "id": "structural-identity-check-q01" }, { "text": "Which authoritative records were read to reconcile the names cortisol and hydrocortisone?", "kind": "provenance", "id": "structural-identity-check-q02" } ] } ] }, { "id": "related-substance-boundaries", "name": "Related substance boundaries", "description": "Separate the parent substance from conversion products, derivatives and formulations.", "findings": [ { "id": "parent-versus-related-entity", "name": "Parent versus related entity", "description": "Classify mentions of cortisone, conjugated cortisol and hydrocortisone esters without merging their identities.", "questions": [ { "text": "Does the name refer to parent cortisol, cortisone, a conjugate, an ester or a finished product?", "kind": "boundary", "id": "parent-versus-related-entity-q01" }, { "text": "If an amount is expressed as cortisol or hydrocortisone equivalent, which actual chemical species and conversion basis underlie it?", "kind": "measurement", "id": "parent-versus-related-entity-q02" } ] } ] } ] }, { "id": "cortisol-material-quality", "name": "Cortisol material quality", "description": "Describe the composition and condition of isolated cortisol and prepared solutions.", "rationale": "A cortisol label does not establish usable content, physical form or stability.", "layers": [ { "id": "lot-composition", "name": "Lot composition", "description": "Qualify cortisol content, impurities and grade using lot-specific evidence.", "findings": [ { "id": "content-and-impurity-evidence", "name": "Content and impurity evidence", "description": "Distinguish measured cortisol content from nominal purity and identify relevant related substances or residual materials.", "questions": [ { "text": "What cortisol content and impurity profile were measured, by which methods and on what reporting basis?", "kind": "measurement", "id": "content-and-impurity-evidence-q01" }, { "text": "Which certificate, lot history or qualification record supports the stated grade and intended use?", "kind": "provenance", "id": "content-and-impurity-evidence-q02" } ] } ] }, { "id": "form-and-stability", "name": "Form and stability", "description": "Record the conditions under which the material's physical state and usable content are established.", "findings": [ { "id": "condition-dependent-properties", "name": "Condition-dependent properties", "description": "Attach physical-property and stability claims to the actual solid form or solution conditions.", "questions": [ { "text": "Which solid form or solution medium is present, and what evidence supports applicable solubility, thermal behavior and storage limits?", "kind": "measurement", "id": "condition-dependent-properties-q01" }, { "text": "After preparation, storage or a temperature excursion, what evidence supports continued use or requires requalification?", "kind": "action", "id": "condition-dependent-properties-q02" } ] } ] } ] }, { "id": "cortisol-biological-context", "name": "Cortisol biological context", "description": "Capture the biological relationships needed to understand cortisol occurrence and change.", "rationale": "Cortisol amount depends on timing, transport, metabolism and exposure rather than on a single interpretation such as stress.", "layers": [ { "id": "origin-and-timing", "name": "Origin and timing", "description": "Locate cortisol observations within organism, sampling and exposure context.", "findings": [ { "id": "production-and-exposure-context", "name": "Production and exposure context", "description": "Record contextual evidence without assuming a measured molecule reveals whether its origin was endogenous or administered.", "questions": [ { "text": "For which organism and physiological context is cortisol being described, and what supports the proposed source?", "kind": "provenance", "id": "production-and-exposure-context-q01" }, { "text": "When was the sample collected relative to waking, sleep, relevant events and hydrocortisone or other glucocorticoid exposure?", "kind": "measurement", "id": "production-and-exposure-context-q02" } ] } ] }, { "id": "binding-and-conversion", "name": "Binding and conversion", "description": "Connect cortisol to its bound and free fractions and to relevant metabolic relationships.", "findings": [ { "id": "availability-and-metabolism", "name": "Availability and metabolism", "description": "Keep circulating amount, free fraction, local availability and conversion to or from cortisone conceptually distinct.", "questions": [ { "text": "Does the observation concern free cortisol, protein-bound cortisol, total cortisol or a tissue-specific quantity?", "kind": "definition", "id": "availability-and-metabolism-q01" }, { "text": "Which documented binding or cortisol-cortisone conversion factors are relevant to interpreting this observation?", "kind": "boundary", "id": "availability-and-metabolism-q02" } ] } ] } ] }, { "id": "cortisol-measurement", "name": "Cortisol measurement", "description": "Define what a cortisol result measures and whether it can be compared with another result.", "rationale": "Specimen, collection interval and analytical specificity materially change the meaning of a cortisol value.", "layers": [ { "id": "specimen-and-observable", "name": "Specimen and observable", "description": "Describe collection and the exact reported quantity.", "findings": [ { "id": "measurement-context-completeness", "name": "Measurement context completeness", "description": "Require enough specimen and collection information to distinguish an instantaneous concentration from an interval-based result.", "questions": [ { "text": "What matrix, cortisol fraction, units and collection time or interval define the reported quantity?", "kind": "measurement", "id": "measurement-context-completeness-q01" }, { "text": "What collection completeness, contamination, processing and storage evidence establishes specimen suitability?", "kind": "provenance", "id": "measurement-context-completeness-q02" } ] } ] }, { "id": "analytical-specificity", "name": "Analytical specificity", "description": "Qualify the method, calibration and interpretation limits.", "findings": [ { "id": "result-comparability", "name": "Result comparability", "description": "Evaluate whether method specificity and contextual differences permit comparison or conversion.", "questions": [ { "text": "Which assay, calibration traceability, quantification limits and known interferences support this cortisol result?", "kind": "measurement", "id": "result-comparability-q01" }, { "text": "Are the matrix, fraction, timing, method and reference population compatible with the proposed comparison?", "kind": "boundary", "id": "result-comparability-q02" }, { "text": "What missing information or confirmatory measurement is needed before acting on an unexpected result?", "kind": "action", "id": "result-comparability-q03" } ] } ] } ] }, { "id": "cortisol-use-constraints", "name": "Cortisol use constraints", "description": "Connect handling and intended use to evidence for the actual cortisol material.", "rationale": "Biological familiarity and chemical identity do not establish safe handling or qualification for every use.", "layers": [ { "id": "handling-evidence", "name": "Handling evidence", "description": "Determine applicable requirements for a specified form, concentration and activity.", "findings": [ { "id": "material-specific-handling", "name": "Material-specific handling", "description": "Ground handling, exposure control and disposal decisions in current documentation rather than inferred hazard labels.", "questions": [ { "text": "Which current safety documentation applies to this cortisol material, concentration, solvent and jurisdiction?", "kind": "provenance", "id": "material-specific-handling-q01" }, { "text": "What handling, containment, storage and disposal measures does that evidence require for the proposed activity?", "kind": "action", "id": "material-specific-handling-q02" } ] } ] }, { "id": "qualification-for-use", "name": "Qualification for use", "description": "Establish whether documented quality supports the intended role.", "findings": [ { "id": "intended-use-gate", "name": "Intended use gate", "description": "Assess suitability for research, calibration or manufacturing while routing finished-medicine decisions to their own model.", "questions": [ { "text": "What documented quality and traceability requirements must this cortisol material meet for its proposed use?", "kind": "action", "id": "intended-use-gate-q01" }, { "text": "Does the requested decision concern the substance itself or require a separate medicinal-product, manufacturing or clinical model?", "kind": "boundary", "id": "intended-use-gate-q02" } ] } ] } ] }, { "id": "evidence-and-external-alignment", "name": "Evidence and external alignment", "description": "What the world already says about this thing, gathered so the model can be checked against it.", "rationale": "A model that cannot be lined up against existing standards, identifiers and practice cannot be adopted by anyone who already uses them.", "layers": [ { "id": "reported-evidence", "name": "Reported evidence", "description": "Findings from the breadth pass, kept separate from the structural claims.", "findings": [ { "id": "evidence-confidence-notes", "name": "Check these first", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "This is recalled knowledge; no sources were consulted.", "Biological reference intervals require the specimen type, collection time, assay and laboratory population; no universal interval is supplied.", "Current pharmacopoeial requirements, jurisdiction-specific regulation and grade-specific hazard classifications require verification." ], "questions": [ { "id": "evidence-confidence-notes-q01", "text": "Which of these check these first hold for the sense of cortisol this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-identifiers", "name": "Identifiers and schemes", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "scheme": "CAS Registry Number", "value_or_pattern": "50-23-7", "note": "Identifies cortisol itself, not its ester derivatives." }, { "scheme": "PubChem CID", "value_or_pattern": "5754", "note": "Recalled identifier for cortisol." }, { "scheme": "Molecular formula", "value_or_pattern": "C21H30O5", "note": "Describes elemental composition but does not distinguish stereoisomers." }, { "scheme": "International Nonproprietary Name", "value_or_pattern": "hydrocortisone", "note": "The pharmaceutical name for the same molecule." } ], "questions": [ { "id": "evidence-identifiers-q01", "text": "Which of these identifiers and schemes hold for the sense of cortisol this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-standards-and-regulation", "name": "Standards and regulation", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "United States Pharmacopeia: the Hydrocortisone monograph specifies pharmaceutical substance identity and quality requirements.", "European Pharmacopoeia, published by the EDQM: the Hydrocortisone monograph specifies pharmaceutical substance quality requirements." ], "questions": [ { "id": "evidence-standards-and-regulation-q01", "text": "Which of these standards and regulation hold for the sense of cortisol this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-real-world-use", "name": "Real-world use", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Endogenous regulation of glucose metabolism, immune responses and adaptation to stress.", "Hydrocortisone medicines for glucocorticoid replacement and treatment of inflammatory conditions.", "Measurement in serum, saliva or urine to investigate adrenal function and cortisol secretion.", "Reference material and experimental reagent in analytical chemistry and endocrine research." ], "questions": [ { "id": "evidence-real-world-use-q01", "text": "Which of these real-world use hold for the sense of cortisol this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-measurements", "name": "Typical measurements", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "quantity": "Molar mass", "typical_range": "362.46", "unit": "g/mol" } ], "questions": [ { "id": "evidence-measurements-q01", "text": "Which of these typical measurements hold for the sense of cortisol this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-failure-modes-and-hazards", "name": "Failure modes and hazards", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Sustained endogenous excess can produce the metabolic and systemic abnormalities of Cushing syndrome.", "Inadequate cortisol production can contribute to adrenal insufficiency.", "Systemic medicinal exposure can suppress the hypothalamic-pituitary-adrenal axis and increase susceptibility to infection.", "Interpretation of cortisol measurements can be distorted by sampling time, acute stress, binding-protein changes and assay interference.", "Confusing hydrocortisone with its ester derivatives can lead to errors in formulation identity or stated substance content." ], "questions": [ { "id": "evidence-failure-modes-and-hazards-q01", "text": "Which of these failure modes and hazards hold for the sense of cortisol this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-regional-variation", "name": "Regional variation", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Medicine availability and prescription requirements vary by jurisdiction, formulation, strength and route of administration." ], "questions": [ { "id": "evidence-regional-variation-q01", "text": "Which of these regional variation hold for the sense of cortisol this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-neighbours", "name": "Neighbouring kinds and how to tell them apart", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "name": "hydrocortisone", "difference": "It is the same molecule; the distinction is naming context, especially pharmaceutical use." }, { "name": "cortisone", "difference": "Cortisone has an 11-keto group where cortisol has an 11β-hydroxyl group; enzymes interconvert them." }, { "name": "corticosterone", "difference": "Corticosterone lacks cortisol's 17α-hydroxyl group." }, { "name": "hydrocortisone acetate", "difference": "It is an acetate ester derivative with a different chemical identity and formulation properties." }, { "name": "glucocorticoid", "difference": "Glucocorticoid denotes a hormone and drug class; cortisol is one member." } ], "questions": [ { "id": "evidence-neighbours-q01", "text": "Which of these neighbouring kinds and how to tell them apart hold for the sense of cortisol this model covers, and on what evidence?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Which existing Vercy publication, if any, already owns cortisol or hydrocortisone and should serve as the single source of truth?", "Which authoritative records establish the accepted identifiers, stereochemical representation and synonym boundaries for this registry entry?", "Which physical constants and stability limits are supported for specified cortisol forms and media, and which thermal values reflect decomposition rather than boiling?", "Which specimen- and method-specific interpretation sources adequately address collection timing, binding changes, assay interference and administered hydrocortisone?", "Which current jurisdiction- and material-specific hazard classifications, exposure limits if established, and grade requirements apply to the intended uses?" ], "statistics": { "bundles": 6, "layers": 11, "findings": 18, "questions": 29 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "chemical substance or material", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a cortisol, record what state it is in, and decide what may be done with it.", "whatItIs": "Enable an AI agent to identify cortisol, assess a material sample or biological measurement in context, and determine what handling, comparison or further investigation is justified.", "characteristics": { "substance": "material", "origin": "natural", "agency": "inert", "mobility": "varies" }, "whatYouCanDoWithIt": [ "observed and measured", "consumed or used up" ], "distinguishingFeatures": [ "Described in 69 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a cortisol, and on what evidence are they told apart?" ], "whatItIsMadeOf": "matter you can touch", "physicalCharacter": [ "Mobility varies between examples.", "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state", "use it up, and then need more of it" ], "howItIsRecognised": [ "Not recognisable by sight in any reliable way. Appearance varies with grade, form and additives; identification is by label, by documentation, or by assay." ], "relatedModels": [], "standing": "Described in 69 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one cortisol from another, and a cortisol from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a cortisol, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a cortisol, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a cortisol is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a cortisol, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a cortisol, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a cortisol is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a cortisol sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a cortisol, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a cortisol, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a cortisol is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a cortisol from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a cortisol, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a cortisol, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a cortisol is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "form-and-composition", "name": "Form, composition and condition", "description": "What a cortisol is made of, what shape and size it takes, and what state it is in.", "rationale": "A physical thing can be measured, and a model that cannot record its measurements cannot support any decision that depends on them.", "layers": [ { "id": "form-and-dimensions", "name": "Form and dimensions", "description": "Shape, size, mass and the ranges these take across examples.", "findings": [ { "id": "measurable-dimensions", "name": "Measurable dimensions and their units", "description": "The quantities worth recording and the units they are recorded in.", "questions": [ { "id": "measurable-dimensions-q01", "text": "What identifies and describes the dimensions of a cortisol, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "measurable-dimensions-q02", "text": "Who or what asserted this about the dimensions of a cortisol, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "measurable-dimensions-q03", "text": "What may an agent decide or do once the dimensions of a cortisol is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "material-and-composition", "name": "Material and composition", "description": "Materials, parts and how they are put together.", "findings": [ { "id": "parts-and-materials", "name": "Parts and materials", "description": "What a cortisol is built from and which parts are replaceable.", "questions": [ { "id": "parts-and-materials-q01", "text": "What identifies and describes the composition of a cortisol, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "parts-and-materials-q02", "text": "Who or what asserted this about the composition of a cortisol, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "parts-and-materials-q03", "text": "What may an agent decide or do once the composition of a cortisol is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "condition-and-integrity", "name": "Condition and integrity", "description": "Wear, damage, health and the difference between working and broken.", "findings": [ { "id": "condition-assessment", "name": "Condition, damage and health", "description": "How the condition of a cortisol is judged and by whom.", "questions": [ { "id": "condition-assessment-q01", "text": "What identifies and describes the condition of a cortisol, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "condition-assessment-q02", "text": "Who or what asserted this about the condition of a cortisol, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "condition-assessment-q03", "text": "What may an agent decide or do once the condition of a cortisol is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "place-and-movement", "name": "Place and movement", "description": "Where a cortisol is, how it got there and where it may go (varies).", "rationale": "A thing that can move needs its position recorded with a time, or every later claim about it is about a place it has left.", "layers": [ { "id": "location-and-placement", "name": "Location and placement", "description": "Position, containment and the reference frame the position is given in.", "findings": [ { "id": "position-and-frame", "name": "Position, container and reference frame", "description": "Where a cortisol is, and what that position is measured against.", "questions": [ { "id": "position-and-frame-q01", "text": "What identifies and describes the location of a cortisol, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "position-and-frame-q02", "text": "Who or what asserted this about the location of a cortisol, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "position-and-frame-q03", "text": "What may an agent decide or do once the location of a cortisol is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "movement-and-transfer", "name": "Movement and transfer", "description": "How a cortisol is carried, installed or relocated.", "findings": [ { "id": "movement-events", "name": "Movement events and constraints", "description": "What counts as a movement, what records it and what limits it.", "questions": [ { "id": "movement-events-q01", "text": "What identifies and describes the movement of a cortisol, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "movement-events-q02", "text": "Who or what asserted this about the movement of a cortisol, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "movement-events-q03", "text": "What may an agent decide or do once the movement of a cortisol is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a cortisol passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a cortisol between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a cortisol, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a cortisol, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a cortisol is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a cortisol, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a cortisol is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a cortisol, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a cortisol, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a cortisol is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "use-and-operation", "name": "Use and operation", "description": "What can be done with a cortisol and what it takes to do it.", "rationale": "An agent that can recognise a thing but not act on it has only half a model.", "layers": [ { "id": "intended-use", "name": "Intended use and function", "description": "What a cortisol is for, and what it is used for anyway.", "findings": [ { "id": "function-and-purpose", "name": "Function, purpose and misuse", "description": "The function a cortisol performs and the uses that fall outside it.", "questions": [ { "id": "function-and-purpose-q01", "text": "What identifies and describes the use of a cortisol, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "function-and-purpose-q02", "text": "Who or what asserted this about the use of a cortisol, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "function-and-purpose-q03", "text": "What may an agent decide or do once the use of a cortisol is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "handling-and-procedure", "name": "Handling and procedure", "description": "The steps, skills and tools involved in using a cortisol.", "findings": [ { "id": "procedures-and-skills", "name": "Procedures, skills and required tools", "description": "What an agent needs before it can act on a cortisol at all.", "questions": [ { "id": "procedures-and-skills-q01", "text": "What identifies and describes handling a cortisol, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "procedures-and-skills-q02", "text": "Who or what asserted this about handling a cortisol, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "procedures-and-skills-q03", "text": "What may an agent decide or do once handling a cortisol is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "supply-and-consumption", "name": "Supply and consumption", "description": "Quantities, rates and what running out means.", "findings": [ { "id": "consumption-and-stock", "name": "Consumption, stock and replenishment", "description": "How much of a cortisol there is and how fast it goes.", "questions": [ { "id": "consumption-and-stock-q01", "text": "What identifies and describes the supply of a cortisol, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "consumption-and-stock-q02", "text": "Who or what asserted this about the supply of a cortisol, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "consumption-and-stock-q03", "text": "What may an agent decide or do once the supply of a cortisol is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "composition-and-identity", "name": "Composition, grade and chemical identity", "description": "What cortisol is made of and how pure the thing in hand is.", "rationale": "Grade decides what a substance may be used for, so a model that records only the name cannot support any decision about use.", "layers": [ { "id": "chemical-identity", "name": "Chemical identity", "description": "Formula, structure and the registry numbers that name it unambiguously.", "findings": [ { "id": "identity-record", "name": "Identity and registry numbers", "description": "What identifies this substance across suppliers and regulators.", "questions": [ { "id": "identity-record-q01", "text": "What formula, structure and registry identifiers name cortisol unambiguously?", "kind": "definition" }, { "id": "identity-record-q02", "text": "Which related substances share a name in common use but not an identifier?", "kind": "boundary" } ] } ] }, { "id": "grade-and-impurities", "name": "Grade, purity and impurities", "description": "The specification a batch meets and what else is in it.", "findings": [ { "id": "specification", "name": "Specification and assay", "description": "How purity is stated and measured, and which impurities matter.", "questions": [ { "id": "specification-q01", "text": "What grades of cortisol exist, how is purity assayed, and which impurities are limited?", "kind": "measurement" }, { "id": "specification-q02", "text": "Which use requires which grade, and what happens when a lower grade is substituted?", "kind": "action" } ] } ] } ] }, { "id": "properties-and-behaviour", "name": "Properties and behaviour", "description": "How cortisol behaves under conditions an agent can measure or change.", "rationale": "Physical constants are the part of a substance model that transfers between contexts, and each needs its unit and its conditions.", "layers": [ { "id": "physical-constants", "name": "Physical constants", "description": "Values that hold for the pure substance, with their conditions.", "findings": [ { "id": "constants-record", "name": "Constants and conditions", "description": "The quantities worth recording and the state they apply in.", "questions": [ { "id": "constants-record-q01", "text": "What are the defining physical constants of cortisol, in what units and under what conditions?", "kind": "measurement" }, { "id": "constants-record-q02", "text": "Which of these values change with grade or form rather than being fixed?", "kind": "boundary" } ] } ] }, { "id": "stability-and-reactivity", "name": "Stability and reactivity", "description": "What it reacts with, degrades into, and how it is stored.", "findings": [ { "id": "incompatibilities", "name": "Incompatibilities and degradation", "description": "What must not meet it, and what it becomes over time.", "questions": [ { "id": "incompatibilities-q01", "text": "What is cortisol incompatible with, and what does it degrade into under storage?", "kind": "definition" }, { "id": "incompatibilities-q02", "text": "What storage and handling does that require, and who is competent to do it?", "kind": "action" } ] } ] } ] }, { "id": "hazard-and-regulation", "name": "Hazard classification and regulation", "description": "How cortisol can harm, and what the law says about holding and moving it.", "rationale": "A substance model without its hazard class and its regulatory identity is unusable in exactly the situations that matter.", "layers": [ { "id": "hazard-class", "name": "Hazard classification", "description": "Classified hazards, exposure limits and protective measures.", "findings": [ { "id": "classified-hazards", "name": "Classified hazards and limits", "description": "The classification, the scheme it belongs to, and the limits set.", "questions": [ { "id": "classified-hazards-q01", "text": "How is cortisol classified for hazard, under which scheme, and what exposure limits apply?", "kind": "definition" }, { "id": "classified-hazards-q02", "text": "What protection does handling require, and what must an agent refuse to do without it?", "kind": "action" } ] } ] }, { "id": "regulatory-identity", "name": "Regulatory identity and control", "description": "Registration, restriction and transport rules by jurisdiction.", "findings": [ { "id": "controls", "name": "Controls and jurisdiction", "description": "Where it is restricted and what the restriction attaches to.", "questions": [ { "id": "controls-q01", "text": "Which registrations, restrictions or transport rules cover cortisol, and where?", "kind": "provenance" }, { "id": "controls-q02", "text": "Does the control attach to the substance, its concentration, or its intended use?", "kind": "boundary" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a cortisol came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a cortisol and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a cortisol, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a cortisol, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a cortisol is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a cortisol is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a cortisol, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a cortisol, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a cortisol is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 9, "layers": 20, "findings": 22, "questions": 60 } } } }