{ "model": { "rank": 3936, "code": "thing-q201989", "model_id": "vr.tr.lyme-disease", "name": "Lyme disease", "purpose": "Let an agent explain Lyme disease and its stages, relay transmission, diagnosis, treatment and prevention from infectious disease guidelines in general terms, route people with symptoms to clinicians, present contested topics such as chronic Lyme claims with attribution, and distinguish Lyme disease from other tick-borne infections.", "family": "Thing Registry", "category": "Cross-cutting context", "status": "research-draft", "kind": "thing", "plane": "XCT", "domain": "XCT.STA", "industry": "", "version": "", "url": "/models/thing/q201989/", "tier": 2, "score": 80, "payload": { "layer": "wikidata", "aliases": [ "acrodermatitis chronica atrophicans", "neuroborreliosis", "Lyme arthritis" ], "aliasCount": 3, "merged": 3, "knownIn": 80, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q201989", "url": "https://www.wikidata.org/wiki/Q201989", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-13T13:11:03Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 4, "engine": "claude" }, "metaModel": { "id": "THING-Q201989", "registryId": "vr.tr.lyme-disease", "name": "Lyme disease", "version": "0.2.0-wave.4", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.STA" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q201989/", "model": { "registry_id": "vr.tr.lyme-disease", "name": "Lyme disease", "purpose": "Let an agent explain Lyme disease and its stages, relay transmission, diagnosis, treatment and prevention from infectious disease guidelines in general terms, route people with symptoms to clinicians, present contested topics such as chronic Lyme claims with attribution, and distinguish Lyme disease from other tick-borne infections.", "definition": "A tick-borne infection caused by Borrelia bacteria, the most common vector-borne disease in the Northern Hemisphere, beginning often with the erythema migrans rash and flu-like symptoms and, if untreated, progressing to neuroborreliosis affecting nerves and brain, Lyme arthritis of large joints, carditis and the late skin condition acrodermatitis chronica atrophicans; it is treated with antibiotics, and anyone with a tick bite followed by rash or symptoms should see a clinician.", "what_it_is_for": "Not applicable; a disease.", "affordances": [ "explain stages", "relay diagnosis, treatment and prevention", "route to clinicians", "distinguish related infections" ], "distinguishing_features": [ "Tick-borne", "Staged course", "Antibiotic treatable", "Contested chronic claims" ], "appearance": "Not a visible object; an expanding ring rash in many early cases.", "visual_identification": [ "Borrelia infection from tick bites", "Erythema migrans, neuroborreliosis, Lyme arthritis, acrodermatitis chronica atrophicans", "Anaplasmosis, babesiosis and tick-borne encephalitis are other tick-borne diseases" ], "physical_properties": [ { "quantity": "cause", "typical_range": "Borrelia burgdorferi sensu lato", "unit": "organism", "note": "" }, { "quantity": "vector", "typical_range": "Ixodes ticks", "unit": "note", "note": "" }, { "quantity": "US cases", "typical_range": "about 476000", "unit": "per year", "note": "CDC estimates" }, { "quantity": "named after", "typical_range": "Lyme, Connecticut, 1975", "unit": "note", "note": "" } ], "families_and_kinds": [ "early localised Lyme disease with erythema migrans", "early disseminated disease including neuroborreliosis and carditis", "late Lyme disease including Lyme arthritis and acrodermatitis chronica atrophicans", "post-treatment Lyme disease symptoms", "European and North American variants" ], "related_models": [ { "relation": "is a kind of", "target": "borreliosis", "why": "in registry terms" }, { "relation": "is caused by", "target": "Borrelia burgdorferi", "why": "and related species" }, { "relation": "is transmitted by", "target": "Ixodes tick", "why": "bites" }, { "relation": "is contrasted with", "target": "tick-borne encephalitis", "why": "a viral tick-borne disease" } ], "identifiers": [ { "scheme": "ICD-10", "value_or_pattern": "A69.2", "note": "Lyme disease" }, { "scheme": "MeSH", "value_or_pattern": "D008193", "note": "Lyme Disease" } ], "standards_and_regulation": [ "IDSA, NICE and ESGBOR guidelines", "Notifiable disease rules in many countries", "Tick surveillance programmes" ], "failure_modes_and_hazards": [ "Missed or delayed diagnosis", "Agents giving personal medical advice", "Misinformation about chronic Lyme and unproven treatments" ], "in_scope": [], "out_of_scope": [], "characteristics": [] }, "sources": [], "structure": { "bundles": [ { "id": "understand", "name": "Understand", "description": "What Lyme disease is.", "rationale": "Clinical.", "layers": [ { "id": "definition", "name": "Definition", "description": "Definition and stages.", "findings": [ { "id": "definition-finding", "name": "Definition", "description": "Definition.", "questions": [ { "text": "What is Lyme disease, and how do early, disseminated and late stages including neuroborreliosis, arthritis and acrodermatitis differ?", "kind": "definition" }, { "text": "Is the user describing a tick bite or symptoms of their own, which need a clinician?", "kind": "boundary" } ] } ] }, { "id": "transmission", "name": "Transmission", "description": "Transmission.", "findings": [ { "id": "transmission-finding", "name": "Transmission", "description": "Transmission.", "questions": [ { "text": "How do Ixodes ticks transmit Borrelia, and where is the disease found?", "kind": "provenance" }, { "text": "Which entry fits Ixodes?", "kind": "action" } ] } ] } ] }, { "id": "care", "name": "Care", "description": "Diagnosis and treatment.", "rationale": "Clinical.", "layers": [ { "id": "diagnosis", "name": "Diagnosis", "description": "Diagnosis.", "findings": [ { "id": "diagnosis-finding", "name": "Diagnosis", "description": "Diagnosis.", "questions": [ { "text": "How is Lyme disease diagnosed clinically and by two-tier serology, as guidelines describe?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] }, { "id": "treatment", "name": "Treatment", "description": "Treatment.", "findings": [ { "id": "treatment-finding", "name": "Treatment", "description": "Treatment.", "questions": [ { "text": "What antibiotic treatments do guidelines recommend by stage, in general terms?", "kind": "provenance" }, { "text": "Which sources are cited?", "kind": "provenance" } ] } ] } ] }, { "id": "prevent", "name": "Prevent", "description": "Prevention.", "rationale": "Application.", "layers": [ { "id": "prevention", "name": "Prevention", "description": "Tick avoidance.", "findings": [ { "id": "prevention-finding", "name": "Prevention", "description": "Prevention.", "questions": [ { "text": "How are tick bites prevented and ticks removed safely, as health authorities advise?", "kind": "action" }, { "text": "Which entry fits tick bite?", "kind": "action" } ] } ] }, { "id": "vaccines", "name": "Vaccines", "description": "Vaccines.", "findings": [ { "id": "vaccines-finding", "name": "Vaccines", "description": "Vaccines.", "questions": [ { "text": "What is the status of Lyme vaccines, past and in development?", "kind": "provenance" }, { "text": "Which entry fits Lyme disease vaccine?", "kind": "action" } ] } ] } ] }, { "id": "context", "name": "Context", "description": "Controversy and history.", "rationale": "Context.", "layers": [ { "id": "controversy", "name": "Controversy", "description": "Chronic Lyme debate.", "findings": [ { "id": "controversy-finding", "name": "Controversy", "description": "Controversy.", "questions": [ { "text": "What is the debate about chronic Lyme disease and post-treatment symptoms, with positions of medical bodies and patient groups attributed?", "kind": "provenance" }, { "text": "Is the presentation evidence-based and attributed?", "kind": "boundary" } ] } ] }, { "id": "history", "name": "History", "description": "History.", "findings": [ { "id": "history-finding", "name": "History", "description": "History.", "questions": [ { "text": "How was Lyme disease identified in Connecticut and its cause discovered by Burgdorfer?", "kind": "provenance" }, { "text": "Which entry fits the history of infectious disease?", "kind": "action" } ] } ] } ] } ] }, "openQuestions": [ "Should neuroborreliosis and Lyme arthritis be separate primary entries?", "How should guideline sources be linked?", "The registry entry has merged aliases naming stages and manifestations; should they be split off?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "disease or condition", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a Lyme disease, record what state it is in, and decide what may be done with it.", "whatItIs": "Let an agent explain Lyme disease and its stages, relay transmission, diagnosis, treatment and prevention from infectious disease guidelines in general terms, route people with symptoms to clinicians, present contested topics such as chronic Lyme claims with attribution, and distinguish Lyme disease from other tick-borne infections.", "characteristics": { "substance": "abstract", "origin": "conceptual", "agency": "inert" }, "whatYouCanDoWithIt": [ "observed and measured" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: acrodermatitis chronica atrophicans, neuroborreliosis, Lyme arthritis.", "3 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.", "Described in 80 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a Lyme disease, and on what evidence are they told apart?" ], "whatItIsMadeOf": "an abstraction with no physical instance", "physicalCharacter": [ "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state" ], "howItIsRecognised": [ "Recognised by criteria applied to signs and findings, not by appearance. Two conditions can look identical and be distinguished only by test." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "acrodermatitis chronica atrophicans", "neuroborreliosis", "Lyme arthritis" ] } ], "standing": "Described in 80 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 3 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one Lyme disease from another, and a Lyme disease from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a Lyme disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a Lyme disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a Lyme disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a Lyme disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a Lyme disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a Lyme disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a Lyme disease sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a Lyme disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a Lyme disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a Lyme disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a Lyme disease from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a Lyme disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a Lyme disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a Lyme disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a Lyme disease passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a Lyme disease between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a Lyme disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a Lyme disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a Lyme disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a Lyme disease, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a Lyme disease is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a Lyme disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a Lyme disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a Lyme disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "diagnosis-and-criteria", "name": "Diagnosis, criteria and coding", "description": "What makes a case of Lyme disease a case, and under which revision.", "rationale": "Criteria change between revisions, so a diagnosis without its coding revision cannot be compared with a later one.", "layers": [ { "id": "criteria", "name": "Diagnostic criteria", "description": "The criteria in force and who issues them.", "findings": [ { "id": "criteria-record", "name": "Criteria, issuer and revision", "description": "What must be true for a diagnosis, according to whom.", "questions": [ { "id": "criteria-record-q01", "text": "What criteria define Lyme disease, issued by which body, in which revision?", "kind": "definition" }, { "id": "criteria-record-q02", "text": "What changed between revisions that would reclassify existing cases?", "kind": "boundary" } ] } ] }, { "id": "coding", "name": "Coding and terminology", "description": "The codes used to record it and their mapping.", "findings": [ { "id": "coding-record", "name": "Codes and mappings", "description": "Which classification codes apply and how they map.", "questions": [ { "id": "coding-record-q01", "text": "Which classification and terminology codes cover Lyme disease, and how do they map to each other?", "kind": "definition" }, { "id": "coding-record-q02", "text": "What is lost when a case is mapped from one scheme to another?", "kind": "boundary" } ] } ] } ] }, { "id": "course-and-population", "name": "Course, population and care", "description": "How Lyme disease develops, whom it affects, and what is done about it.", "rationale": "The condition, the diagnosis and the episode of care are three different things, and an agent must not merge them.", "layers": [ { "id": "course", "name": "Course and stages", "description": "Onset, progression, remission and outcome.", "findings": [ { "id": "course-record", "name": "Stages and transitions", "description": "The stages recorded and what moves a case between them.", "questions": [ { "id": "course-record-q01", "text": "What course does Lyme disease typically take, and what marks each stage?", "kind": "definition" }, { "id": "course-record-q02", "text": "What separates the condition itself from an episode of care for it?", "kind": "boundary" } ] } ] }, { "id": "population", "name": "Affected populations", "description": "Who is affected, how often, and on what evidence.", "findings": [ { "id": "epidemiology", "name": "Prevalence and its basis", "description": "Rates with their population, period and source.", "questions": [ { "id": "epidemiology-q01", "text": "What prevalence or incidence is reported for Lyme disease, in which population and period?", "kind": "measurement" }, { "id": "epidemiology-q02", "text": "What may an agent not conclude about an individual from a population rate?", "kind": "action" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a Lyme disease came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a Lyme disease and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a Lyme disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a Lyme disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a Lyme disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a Lyme disease is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a Lyme disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a Lyme disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a Lyme disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 5, "layers": 10, "findings": 12, "questions": 32 } } } }