{ "model": { "rank": 5085, "code": "thing-q212961", "model_id": "vr.tr.pancreatic-cancer", "name": "pancreatic cancer", "purpose": "Let an agent explain pancreatic cancer and its types, risk factors and symptoms in general terms, relay diagnosis, treatment and support information from health bodies, describe research, and route personal medical questions to clinicians with sensitivity.", "family": "Thing Registry", "category": "Cross-cutting context", "status": "research-draft", "kind": "thing", "plane": "XCT", "domain": "XCT.STA", "industry": "", "version": "", "url": "/models/thing/q212961/", "tier": 2, "score": 70, "payload": { "layer": "wikidata", "aliases": [ "Intraductal papillary mucinous neoplasm", "pancreas lymphoma", "cancer of exocrine pancreas", "pancreas sarcoma", "islet cell tumor", "pancreatic carcinoma", "adenosquamous pancreas carcinoma", "secondary malignant neoplasm to the pancreas", "recurrent cancer of pancreas", "exocrine pancreatic cancer", "pancreatic squamous cell carcinoma", "solid pseudopapillary tumour" ], "aliasCount": 12, "merged": 12, "knownIn": 70, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q212961", "url": "https://www.wikidata.org/wiki/Q212961", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-12T06:14:37Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 2, "engine": "claude" }, "metaModel": { "id": "THING-Q212961", "registryId": "vr.tr.pancreatic-cancer", "name": "pancreatic cancer", "version": "0.2.0-wave.2", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.STA" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q212961/", "model": { "registry_id": "vr.tr.pancreatic-cancer", "name": "pancreatic cancer", "purpose": "Let an agent explain pancreatic cancer and its types, risk factors and symptoms in general terms, relay diagnosis, treatment and support information from health bodies, describe research, and route personal medical questions to clinicians with sensitivity.", "definition": "A cancer arising in the pancreas, most often adenocarcinoma of the exocrine pancreas and less often neuroendocrine islet cell tumours, cystic neoplasms such as intraductal papillary mucinous neoplasms with malignant potential, and rare lymphomas and sarcomas, often diagnosed late because early symptoms are vague, and among the cancers with the lowest survival; risk factors include smoking, chronic pancreatitis, diabetes, obesity and inherited syndromes, and treatment involves surgery, chemotherapy, radiotherapy and supportive care under clinical guidelines.", "what_it_is_for": "Cancer of the pancreas.", "affordances": [ "explain types and risk factors", "relay diagnosis and treatment information", "describe research", "route personal questions" ], "distinguishing_features": [ "Often late diagnosis", "Low survival", "Exocrine and endocrine types", "Inherited risk in some" ], "appearance": "Not visible; found by imaging and biopsy.", "visual_identification": [ "Malignant tumour of the pancreas", "Exocrine adenocarcinoma, neuroendocrine, cystic, rare types", "Pancreatitis is inflammation; benign cysts are not cancer" ], "physical_properties": [], "families_and_kinds": [ "pancreatic ductal adenocarcinoma", "pancreatic neuroendocrine tumours", "intraductal papillary mucinous and other cystic neoplasms", "rare pancreatic lymphomas and sarcomas", "hereditary pancreatic cancer syndromes" ], "related_models": [ { "relation": "is a kind of", "target": "gastrointestinal system cancer", "why": "category" }, { "relation": "is a kind of", "target": "endocrine gland cancer", "why": "category" }, { "relation": "is related to", "target": "stomach cancer", "why": "another gastrointestinal cancer" }, { "relation": "is related to", "target": "medical ultrasonography", "why": "endoscopic ultrasound used in diagnosis" } ], "identifiers": [], "standards_and_regulation": [ "Clinical guidelines for pancreatic cancer", "Cancer registry and staging standards", "Drug regulation for cancer therapies" ], "failure_modes_and_hazards": [ "Agents giving personal diagnosis, prognosis or treatment advice", "Unproven treatments", "Insensitive communication" ], "in_scope": [], "out_of_scope": [], "characteristics": [] }, "sources": [], "structure": { "bundles": [ { "id": "understand", "name": "Understand", "description": "What pancreatic cancer is.", "rationale": "General information.", "layers": [ { "id": "concept", "name": "Concept", "description": "Concept and types.", "findings": [ { "id": "concept-finding", "name": "Concept", "description": "Concept.", "questions": [ { "text": "What is pancreatic cancer, and how do exocrine, neuroendocrine, cystic and rare types differ?", "kind": "definition" }, { "text": "Is the user asking about their own or a loved one diagnosis, which needs their clinical team?", "kind": "boundary" } ] } ] }, { "id": "risk", "name": "Risk", "description": "Risk factors and symptoms.", "findings": [ { "id": "risk-finding", "name": "Risk", "description": "Risk.", "questions": [ { "text": "What risk factors and symptoms do health bodies describe, and why is diagnosis often late?", "kind": "provenance" }, { "text": "Is urgent assessment needed for symptoms such as jaundice?", "kind": "boundary" } ] } ] } ] }, { "id": "manage", "name": "Manage", "description": "Diagnosis and treatment.", "rationale": "Guidance.", "layers": [ { "id": "diagnosis", "name": "Diagnosis", "description": "Diagnosis and staging.", "findings": [ { "id": "diagnosis-finding", "name": "Diagnosis", "description": "Diagnosis.", "questions": [ { "text": "How is pancreatic cancer diagnosed and staged with imaging, endoscopic ultrasound and biopsy, in general terms?", "kind": "provenance" }, { "text": "Which entry fits cancer staging?", "kind": "action" } ] } ] }, { "id": "treatment", "name": "Treatment", "description": "Treatment and support.", "findings": [ { "id": "treatment-finding", "name": "Treatment", "description": "Treatment.", "questions": [ { "text": "What treatments and supportive and palliative care do guidelines describe, in general terms?", "kind": "provenance" }, { "text": "Is the presentation free of unproven treatment claims and sensitive in tone?", "kind": "boundary" } ] } ] } ] }, { "id": "science", "name": "Science", "description": "Research and prevention.", "rationale": "Science.", "layers": [ { "id": "research", "name": "Research", "description": "Research.", "findings": [ { "id": "research-finding", "name": "Research", "description": "Research.", "questions": [ { "text": "What research is under way on early detection and new therapies, with findings attributed?", "kind": "provenance" }, { "text": "Which findings are contested?", "kind": "boundary" } ] } ] }, { "id": "prevention", "name": "Prevention", "description": "Prevention and screening.", "findings": [ { "id": "prevention-finding", "name": "Prevention", "description": "Prevention.", "questions": [ { "text": "What do health bodies say about risk reduction and surveillance for high-risk families?", "kind": "provenance" }, { "text": "Which entry fits genetic counselling?", "kind": "action" } ] } ] } ] }, { "id": "learn", "name": "Learn", "description": "Support and teaching.", "rationale": "Education.", "layers": [ { "id": "support", "name": "Support", "description": "Support organisations.", "findings": [ { "id": "support-finding", "name": "Support", "description": "Support.", "questions": [ { "text": "Which patient organisations and resources support people affected by pancreatic cancer?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] }, { "id": "teach", "name": "Teach", "description": "Teaching.", "findings": [ { "id": "teach-finding", "name": "Teach", "description": "Teaching.", "questions": [ { "text": "How can pancreatic cancer be taught in oncology education?", "kind": "action" }, { "text": "Which misconceptions arise?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Should neuroendocrine tumours be a separate entry?", "How should guidelines be linked?", "How should patient organisations be linked?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "disease or condition", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a pancreatic cancer, record what state it is in, and decide what may be done with it.", "whatItIs": "Let an agent explain pancreatic cancer and its types, risk factors and symptoms in general terms, relay diagnosis, treatment and support information from health bodies, describe research, and route personal medical questions to clinicians with sensitivity.", "characteristics": { "substance": "abstract", "origin": "conceptual", "agency": "inert" }, "whatYouCanDoWithIt": [ "observed and measured" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: Intraductal papillary mucinous neoplasm, pancreas lymphoma, cancer of exocrine pancreas, pancreas sarcoma, islet cell tumor, pancreatic carcinoma, adenosquamous pancreas carcinoma, secondary malignant neoplasm to the pancreas, recurrent cancer of pancreas, exocrine pancreatic cancer, pancreatic squamous cell carcinoma, solid pseudopapillary tumour.", "12 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.", "Described in 70 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a pancreatic cancer, and on what evidence are they told apart?" ], "whatItIsMadeOf": "an abstraction with no physical instance", "physicalCharacter": [ "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state" ], "howItIsRecognised": [ "Recognised by criteria applied to signs and findings, not by appearance. Two conditions can look identical and be distinguished only by test." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "Intraductal papillary mucinous neoplasm", "pancreas lymphoma", "cancer of exocrine pancreas", "pancreas sarcoma", "islet cell tumor", "pancreatic carcinoma", "adenosquamous pancreas carcinoma", "secondary malignant neoplasm to the pancreas", "recurrent cancer of pancreas", "exocrine pancreatic cancer", "pancreatic squamous cell carcinoma", "solid pseudopapillary tumour" ] } ], "standing": "Described in 70 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 12 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one pancreatic cancer from another, and a pancreatic cancer from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a pancreatic cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a pancreatic cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a pancreatic cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a pancreatic cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a pancreatic cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a pancreatic cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a pancreatic cancer sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a pancreatic cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a pancreatic cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a pancreatic cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a pancreatic cancer from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a pancreatic cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a pancreatic cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a pancreatic cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a pancreatic cancer passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a pancreatic cancer between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a pancreatic cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a pancreatic cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a pancreatic cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a pancreatic cancer, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a pancreatic cancer is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a pancreatic cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a pancreatic cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a pancreatic cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "diagnosis-and-criteria", "name": "Diagnosis, criteria and coding", "description": "What makes a case of pancreatic cancer a case, and under which revision.", "rationale": "Criteria change between revisions, so a diagnosis without its coding revision cannot be compared with a later one.", "layers": [ { "id": "criteria", "name": "Diagnostic criteria", "description": "The criteria in force and who issues them.", "findings": [ { "id": "criteria-record", "name": "Criteria, issuer and revision", "description": "What must be true for a diagnosis, according to whom.", "questions": [ { "id": "criteria-record-q01", "text": "What criteria define pancreatic cancer, issued by which body, in which revision?", "kind": "definition" }, { "id": "criteria-record-q02", "text": "What changed between revisions that would reclassify existing cases?", "kind": "boundary" } ] } ] }, { "id": "coding", "name": "Coding and terminology", "description": "The codes used to record it and their mapping.", "findings": [ { "id": "coding-record", "name": "Codes and mappings", "description": "Which classification codes apply and how they map.", "questions": [ { "id": "coding-record-q01", "text": "Which classification and terminology codes cover pancreatic cancer, and how do they map to each other?", "kind": "definition" }, { "id": "coding-record-q02", "text": "What is lost when a case is mapped from one scheme to another?", "kind": "boundary" } ] } ] } ] }, { "id": "course-and-population", "name": "Course, population and care", "description": "How pancreatic cancer develops, whom it affects, and what is done about it.", "rationale": "The condition, the diagnosis and the episode of care are three different things, and an agent must not merge them.", "layers": [ { "id": "course", "name": "Course and stages", "description": "Onset, progression, remission and outcome.", "findings": [ { "id": "course-record", "name": "Stages and transitions", "description": "The stages recorded and what moves a case between them.", "questions": [ { "id": "course-record-q01", "text": "What course does pancreatic cancer typically take, and what marks each stage?", "kind": "definition" }, { "id": "course-record-q02", "text": "What separates the condition itself from an episode of care for it?", "kind": "boundary" } ] } ] }, { "id": "population", "name": "Affected populations", "description": "Who is affected, how often, and on what evidence.", "findings": [ { "id": "epidemiology", "name": "Prevalence and its basis", "description": "Rates with their population, period and source.", "questions": [ { "id": "epidemiology-q01", "text": "What prevalence or incidence is reported for pancreatic cancer, in which population and period?", "kind": "measurement" }, { "id": "epidemiology-q02", "text": "What may an agent not conclude about an individual from a population rate?", "kind": "action" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a pancreatic cancer came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a pancreatic cancer and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a pancreatic cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a pancreatic cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a pancreatic cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a pancreatic cancer is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a pancreatic cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a pancreatic cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a pancreatic cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 5, "layers": 10, "findings": 12, "questions": 32 } } } }