{ "model": { "rank": 6735, "code": "thing-q261327", "model_id": "vr.tr.thrombosis", "name": "thrombosis", "purpose": "Let an agent explain thrombosis and its types, causes and complications, relay prevention, symptom and treatment information from health bodies and regulators, and route personal medical questions to clinicians and emergencies to services.", "family": "Thing Registry", "category": "Cross-cutting context", "status": "research-draft", "kind": "thing", "plane": "XCT", "domain": "XCT.STA", "industry": "", "version": "", "url": "/models/thing/q261327/", "tier": 2, "score": 59, "payload": { "layer": "wikidata", "aliases": [ "marantic endocarditis", "thromboinflammation", "embolic and thrombotic events after COVID-19 vaccination", "mesenteric thrombosis", "ovarian vein thrombosis", "portal vein thrombosis", "stent thrombosis", "venous thrombosis", "arterial thrombosis", "Phlebothrombosis", "Thrombotic storm", "thromboembolism", "feline arterial thromboembolism", "Pylephlebitis", "Cerebral venous thrombosis", "Jugular vein thrombosis", "renal vein thrombosis", "superficial vein thrombosis", "systemic thromboembolism", "venous thromboembolism" ], "aliasCount": 20, "merged": 20, "knownIn": 59, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q261327", "url": "https://www.wikidata.org/wiki/Q261327", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-12T04:14:57Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 2, "engine": "claude" }, "metaModel": { "id": "THING-Q261327", "registryId": "vr.tr.thrombosis", "name": "thrombosis", "version": "0.2.0-wave.2", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.STA" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q261327/", "model": { "registry_id": "vr.tr.thrombosis", "name": "thrombosis", "purpose": "Let an agent explain thrombosis and its types, causes and complications, relay prevention, symptom and treatment information from health bodies and regulators, and route personal medical questions to clinicians and emergencies to services.", "definition": "The formation of a blood clot, or thrombus, inside a blood vessel that obstructs blood flow, occurring in veins as deep vein and portal, mesenteric or ovarian vein thrombosis and in arteries causing heart attacks and strokes, with clots that break off causing embolism; thrombosis arises from vessel injury, slowed flow and increased clotting tendency, is linked to inflammation as thromboinflammation, and is prevented and treated with anticoagulants and other measures under clinical guidelines, with rare events after some vaccines monitored and characterised by regulators.", "what_it_is_for": "Blood clots obstructing vessels.", "affordances": [ "explain types and causes", "relay prevention and treatment information", "describe rare vaccine-associated events with attribution", "route personal questions" ], "distinguishing_features": [ "Clot formation in vessels", "Venous and arterial forms", "Embolism risk", "Anticoagulant treatment" ], "appearance": "Not physical as a concept; clots seen on imaging.", "visual_identification": [ "Clot forming within a blood vessel", "Venous or arterial", "Embolism is a travelling clot; haemorrhage is bleeding" ], "physical_properties": [], "families_and_kinds": [ "deep vein thrombosis and pulmonary embolism", "arterial thrombosis in heart attack and stroke", "thrombosis of abdominal and pelvic veins", "thrombosis in cancer and inflammatory conditions", "rare vaccine-associated thrombotic syndromes as characterised by regulators" ], "related_models": [ { "relation": "is a kind of", "target": "embolism and thrombosis", "why": "category" }, { "relation": "is a kind of", "target": "hematologic disorder", "why": "category" }, { "relation": "is related to", "target": "vaccine", "why": "rare monitored adverse events" }, { "relation": "is related to", "target": "emergency", "why": "thrombosis as a medical emergency" } ], "identifiers": [], "standards_and_regulation": [ "Clinical guidelines for venous and arterial thrombosis", "Pharmacovigilance on rare vaccine-associated events", "Medicines regulation for anticoagulants" ], "failure_modes_and_hazards": [ "Agents giving personal medical advice", "Missing emergency signs such as chest pain or stroke symptoms", "Misrepresenting rare vaccine events without regulator context" ], "in_scope": [], "out_of_scope": [], "characteristics": [] }, "sources": [], "structure": { "bundles": [ { "id": "act", "name": "Act", "description": "Emergency signs.", "rationale": "Safety first.", "layers": [ { "id": "signs", "name": "Signs", "description": "Warning signs.", "findings": [ { "id": "signs-finding", "name": "Signs", "description": "Signs.", "questions": [ { "text": "Which symptoms of thrombosis and embolism do health bodies identify as emergencies requiring immediate care?", "kind": "provenance" }, { "text": "Is a possible thrombosis or embolism happening now, requiring emergency services?", "kind": "boundary" } ] } ] }, { "id": "seek", "name": "Seek", "description": "Seeking care.", "findings": [ { "id": "seek-finding", "name": "Seek", "description": "Seeking care.", "questions": [ { "text": "How should someone with suspected thrombosis seek care?", "kind": "provenance" }, { "text": "Which entry fits emergency medical services?", "kind": "action" } ] } ] } ] }, { "id": "understand", "name": "Understand", "description": "What thrombosis is.", "rationale": "General information.", "layers": [ { "id": "mechanism", "name": "Mechanism", "description": "Mechanism and types.", "findings": [ { "id": "mechanism-finding", "name": "Mechanism", "description": "Mechanism.", "questions": [ { "text": "How do vessel injury, slowed flow and clotting tendency cause thrombosis, and how do venous and arterial forms differ?", "kind": "definition" }, { "text": "Is the user asking about their own risk, which needs a clinician?", "kind": "boundary" } ] } ] }, { "id": "risks", "name": "Risks", "description": "Risk factors.", "findings": [ { "id": "risks-finding", "name": "Risks", "description": "Risks.", "questions": [ { "text": "What risk factors such as immobility, surgery, cancer, hormones and inherited conditions are described by health bodies?", "kind": "provenance" }, { "text": "Which entry fits a specific risk factor?", "kind": "action" } ] } ] } ] }, { "id": "care", "name": "Care", "description": "Prevention and treatment.", "rationale": "Guidelines.", "layers": [ { "id": "prevent", "name": "Prevent", "description": "Prevention.", "findings": [ { "id": "prevent-finding", "name": "Prevent", "description": "Prevention.", "questions": [ { "text": "How is thrombosis prevented in hospital, travel and daily life, according to guidelines?", "kind": "provenance" }, { "text": "Which entry fits anticoagulants?", "kind": "action" } ] } ] }, { "id": "vaccines", "name": "Vaccines", "description": "Rare vaccine-associated events.", "findings": [ { "id": "vaccines-finding", "name": "Vaccines", "description": "Vaccines.", "questions": [ { "text": "What have regulators concluded about rare thrombotic events after certain vaccines, and how do they weigh benefits and risks, with findings attributed?", "kind": "provenance" }, { "text": "Is the presentation grounded in regulator findings?", "kind": "boundary" } ] } ] } ] }, { "id": "learn", "name": "Learn", "description": "Epidemiology and history.", "rationale": "Education.", "layers": [ { "id": "epidemiology", "name": "Epidemiology", "description": "Epidemiology.", "findings": [ { "id": "epidemiology-finding", "name": "Epidemiology", "description": "Epidemiology.", "questions": [ { "text": "How common is thrombosis, and what is its burden worldwide?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] }, { "id": "history", "name": "History", "description": "History.", "findings": [ { "id": "history-finding", "name": "History", "description": "History.", "questions": [ { "text": "How did understanding of thrombosis develop from Virchow to modern anticoagulation?", "kind": "provenance" }, { "text": "Which misconceptions arise?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Should venous and arterial thrombosis be separate entries?", "How should guidelines be linked?", "How should pharmacovigilance reports be linked?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "disease or condition", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a thrombosis, record what state it is in, and decide what may be done with it.", "whatItIs": "Let an agent explain thrombosis and its types, causes and complications, relay prevention, symptom and treatment information from health bodies and regulators, and route personal medical questions to clinicians and emergencies to services.", "characteristics": { "substance": "abstract", "origin": "conceptual", "agency": "inert" }, "whatYouCanDoWithIt": [ "observed and measured" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: marantic endocarditis, thromboinflammation, embolic and thrombotic events after COVID-19 vaccination, mesenteric thrombosis, ovarian vein thrombosis, portal vein thrombosis, stent thrombosis, venous thrombosis, arterial thrombosis, Phlebothrombosis, Thrombotic storm, thromboembolism.", "20 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.", "Described in 59 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a thrombosis, and on what evidence are they told apart?" ], "whatItIsMadeOf": "an abstraction with no physical instance", "physicalCharacter": [ "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state" ], "howItIsRecognised": [ "Recognised by criteria applied to signs and findings, not by appearance. Two conditions can look identical and be distinguished only by test." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "marantic endocarditis", "thromboinflammation", "embolic and thrombotic events after COVID-19 vaccination", "mesenteric thrombosis", "ovarian vein thrombosis", "portal vein thrombosis", "stent thrombosis", "venous thrombosis", "arterial thrombosis", "Phlebothrombosis", "Thrombotic storm", "thromboembolism" ] } ], "standing": "Described in 59 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 20 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one thrombosis from another, and a thrombosis from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a thrombosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a thrombosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a thrombosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a thrombosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a thrombosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a thrombosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a thrombosis sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a thrombosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a thrombosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a thrombosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a thrombosis from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a thrombosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a thrombosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a thrombosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a thrombosis passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a thrombosis between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a thrombosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a thrombosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a thrombosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a thrombosis, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a thrombosis is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a thrombosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a thrombosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a thrombosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "diagnosis-and-criteria", "name": "Diagnosis, criteria and coding", "description": "What makes a case of thrombosis a case, and under which revision.", "rationale": "Criteria change between revisions, so a diagnosis without its coding revision cannot be compared with a later one.", "layers": [ { "id": "criteria", "name": "Diagnostic criteria", "description": "The criteria in force and who issues them.", "findings": [ { "id": "criteria-record", "name": "Criteria, issuer and revision", "description": "What must be true for a diagnosis, according to whom.", "questions": [ { "id": "criteria-record-q01", "text": "What criteria define thrombosis, issued by which body, in which revision?", "kind": "definition" }, { "id": "criteria-record-q02", "text": "What changed between revisions that would reclassify existing cases?", "kind": "boundary" } ] } ] }, { "id": "coding", "name": "Coding and terminology", "description": "The codes used to record it and their mapping.", "findings": [ { "id": "coding-record", "name": "Codes and mappings", "description": "Which classification codes apply and how they map.", "questions": [ { "id": "coding-record-q01", "text": "Which classification and terminology codes cover thrombosis, and how do they map to each other?", "kind": "definition" }, { "id": "coding-record-q02", "text": "What is lost when a case is mapped from one scheme to another?", "kind": "boundary" } ] } ] } ] }, { "id": "course-and-population", "name": "Course, population and care", "description": "How thrombosis develops, whom it affects, and what is done about it.", "rationale": "The condition, the diagnosis and the episode of care are three different things, and an agent must not merge them.", "layers": [ { "id": "course", "name": "Course and stages", "description": "Onset, progression, remission and outcome.", "findings": [ { "id": "course-record", "name": "Stages and transitions", "description": "The stages recorded and what moves a case between them.", "questions": [ { "id": "course-record-q01", "text": "What course does thrombosis typically take, and what marks each stage?", "kind": "definition" }, { "id": "course-record-q02", "text": "What separates the condition itself from an episode of care for it?", "kind": "boundary" } ] } ] }, { "id": "population", "name": "Affected populations", "description": "Who is affected, how often, and on what evidence.", "findings": [ { "id": "epidemiology", "name": "Prevalence and its basis", "description": "Rates with their population, period and source.", "questions": [ { "id": "epidemiology-q01", "text": "What prevalence or incidence is reported for thrombosis, in which population and period?", "kind": "measurement" }, { "id": "epidemiology-q02", "text": "What may an agent not conclude about an individual from a population rate?", "kind": "action" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a thrombosis came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a thrombosis and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a thrombosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a thrombosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a thrombosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a thrombosis is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a thrombosis, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a thrombosis, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a thrombosis is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 5, "layers": 10, "findings": 12, "questions": 32 } } } }